{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:01:19Z","timestamp":1792598479704,"version":"4.5.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T00:00:00Z","timestamp":1696636800000},"content-version":"vor","delay-in-days":371,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100010032","name":"Health and Family Planning Commission of Sichuan Province","doi-asserted-by":"publisher","award":["201540237"],"award-info":[{"award-number":["201540237"]}],"id":[{"id":"10.13039\/501100010032","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["202040127"],"award-info":[{"award-number":["202040127"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81501319"],"award-info":[{"award-number":["81501319"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.fertnstert.2022.06.012","type":"journal-article","created":{"date-parts":[[2022,8,6]],"date-time":"2022-08-06T14:44:27Z","timestamp":1659797067000},"page":"701-712","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Comparison of the cumulative live birth rates after 1 in\u00a0vitro fertilization cycle in women using gonadotropin-releasing hormone antagonist protocol vs. progestin-primed ovarian stimulation: a propensity score\u2013matched study"],"prefix":"10.1016","volume":"118","author":[{"given":"Hong","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Ming","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi Li","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0591-5395","authenticated-orcid":false,"given":"Zhi Qin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2022.06.012_bib1","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.rbmo.2014.02.003","article-title":"Novel aspects of the endocrinology of the menstrual cycle","volume":"28","author":"Messinis","year":"2014","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib2","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/humupd\/8.2.129","article-title":"Efficacy of natural cycle IVF: a review of the literature","volume":"8","author":"Pelinck","year":"2002","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib3","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/humupd\/6.4.307","article-title":"Regulation of follicle development and novel approaches to ovarian stimulation for IVF","volume":"6","author":"Smacklon","year":"2000","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1477-7827-10-26","article-title":"GnRH agonist versus GnRH antagonist in in vitro fertilization and embryo transfer (IVF\/ET)","volume":"10","author":"Depalo","year":"2012","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib5","doi-asserted-by":"crossref","first-page":"170","DOI":"10.4103\/0974-1208.142476","article-title":"Gonadotropin-releasing hormone analogs: understanding advantages and limitations","volume":"7","author":"Kumar","year":"2014","journal-title":"J Hum Reprod Sci"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib6","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/humupd\/dml001","article-title":"GnRH antagonists in ovarian stimulation for IVF","volume":"12","author":"Tarlatzis","year":"2006","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib7","first-page":"CD001750","article-title":"Gonadotrophin-releasing hormone antagonists for assisted reproductive technology","volume":"4","author":"Al-Inany","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib8","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.fertnstert.2015.03.022","article-title":"Medroxyprogesterone acetate is an effective oral alternative for preventing premature luteinizing hormone surges in women undergoing controlled ovarian hyperstimulation for in\u00a0vitro fertilization","volume":"104","author":"Kuang","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib9","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00404-018-4856-8","article-title":"New trial of progestin-primed ovarian stimulation using dydrogesterone versus a typical GnRH antagonist regimen in assisted reproductive technology","volume":"298","author":"Iwami","year":"2018","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib10","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1093\/humrep\/dez034","article-title":"Medroxyprogesterone acetate versus ganirelix in oocyte donation: a randomized controlled trial","volume":"34","author":"Beguer\u00eda","year":"2019","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib11","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.fertnstert.2019.06.009","article-title":"Comparison of a novel flexible progestin primed ovarian stimulation protocol and the flexible gonadotropin-releasing hormone antagonist protocol for assisted reproductive technology","volume":"112","author":"Yildiz","year":"2019","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib12","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.rbmo.2020.01.027","article-title":"Progestins versus GnRH analogues for pituitary suppression during ovarian stimulation for assisted reproductive technology: a systematic review and meta-analysis","volume":"40","author":"Alexandru","year":"2020","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib13","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1111\/1471-0528.14622","article-title":"The pregnancy outcome of progestin-primed ovarian stimulation using 4 versus 10 mg of medroxyprogesterone acetate per day in infertile women undergoing in\u00a0vitro fertilisation: a randomised controlled trial","volume":"124","author":"Dong","year":"2017","journal-title":"BJOG"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib14","first-page":"e2939","article-title":"Controlled ovarian stimulation using medroxyprogesterone acetate and hMG in patients with polycystic ovary syndrome treated for IVF: a double-blind randomized crossover clinical trial","volume":"95","author":"Wang","year":"2016","journal-title":"Medicine(Baltimore)"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib15","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1093\/humupd\/dmaa040","article-title":"Progestins for pituitary suppression during ovarian stimulation for ART: a comprehensive and systematic review including meta-analyses","volume":"27","author":"Ata","year":"2021","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fendo.2019.00796","article-title":"Progestin vs. gonadotropin-releasing hormone antagonist for the prevention of premature luteinizing hormone surges in poor responders undergoing in vitro fertilization treatment: a randomized controlled trial","volume":"10","author":"Chen","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib17","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1749-6632.1988.tb22263.x","article-title":"Oocyte assessment and biological performance","volume":"541","author":"Veeck","year":"1988","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib18","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1093\/humrep\/dey333","article-title":"A randomized triple blind controlled trial comparing the live birth rate of IVF following brief incubation versus standard incubation of gametes","volume":"34","author":"Chen","year":"2019","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib19","first-page":"671","article-title":"Progesterone-primed ovarian stimulation in polycystic ovarian syndrome: an RCT","volume":"17","author":"Eftekhar","year":"2019","journal-title":"Int J Reprod Biomed"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib20","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jogoh.2018.10.008","article-title":"Progestin-primed ovarian stimulation is a feasible method for poor ovarian responders undergoing in IVF\/ICSI compared to a GnRH antagonist protocol: a retrospective study","volume":"48","author":"Huang","year":"2019","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib21","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1080\/14647273.2020.1794060","article-title":"Effectiveness of the flexible progestin primed ovarian stimulation protocol compared to the flexible GnRH antagonist protocol in women with decreased ovarian reserve","volume":"25","author":"Turkgeldi","year":"2022","journal-title":"Hum Fertil (Camb)"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib22","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1056\/NEJMoa1110238","article-title":"Cumulative birth rates with linked assisted reproductive technology cycles","volume":"366","author":"Luke","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib23","first-page":"2703","article-title":"Cumulative live birth rate: time for a consensus?","volume":"30","author":"Maheshwari","year":"2015","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/humrep\/dev270","article-title":"How do cumulative live birth rates and cumulative multiple live birth rates over complete courses of assisted reproductive technology treatment per woman compare among registries?","volume":"31","author":"De Neubourg","year":"2016","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib25","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1093\/humrep\/dev336","article-title":"Cumulative live birth rates after one or more complete cycles of IVF: a population-based study of linked cycle data from 178,898 women","volume":"31","author":"McLernon","year":"2016","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib26","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1056\/NEJMc0907289","article-title":"Cumulative live-birth rates in a trial of single-embryo or double-embryo transfer","volume":"361","author":"Thurin-Kjellberg","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib27","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.rbmo.2019.03.212","article-title":"Use of progestins to inhibit spontaneous ovulation during ovarian stimulation: the beginning of a new era?","volume":"39","author":"La Marca","year":"2019","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib28","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.fertnstert.2019.12.025","article-title":"Time to pregnancy: as important for patients as underestimated by doctors","volume":"113","author":"Roque","year":"2020","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib29","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jclinepi.2005.07.004","article-title":"A review of the application of propensity score methods yielded increasing use, advantages in specific settings, but not substantially different estimates compared with conventional multivariable methods","volume":"59","author":"St\u00fcrmer","year":"2006","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib30","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/00273171.2011.568786","article-title":"An introduction to propensity score methods for reducing the effects of confounding in observational studies","volume":"46","author":"Austin","year":"2011","journal-title":"Multivariate Behav Res"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib31","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/humupd\/dmz037","article-title":"Ovarian stimulation for freeze-all IVF cycles: a systematic review","volume":"26","author":"Mizrachi","year":"2020","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2022.06.012_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/hropen\/hoz004","article-title":"Cumulative live birth rates following a \u2018freeze-all\u2019strategy: a population-based study","volume":"2019","author":"Li","year":"2019","journal-title":"Hum Reprod Open"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028222003909?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028222003909?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:36:14Z","timestamp":1758011774000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028222003909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0015028222003909"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2022.06.012","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of the cumulative live birth rates after 1 in\u00a0vitro fertilization cycle in women using gonadotropin-releasing hormone antagonist protocol vs. progestin-primed ovarian stimulation: a propensity score\u2013matched study","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2022.06.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92022 American Society for Reproductive Medicine, Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}