{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:14:16Z","timestamp":1791378856508,"version":"4.3.2"},"reference-count":52,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012665","name":"Institute for Clinical Evaluative Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000031","name":"CIHR IHDCYH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000031","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001350","name":"Ministry of Health -Singapore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001350","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.fertnstert.2022.09.015","type":"journal-article","created":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T21:06:23Z","timestamp":1666731983000},"page":"1090-1099","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Mode of conception in patients with endometriosis and adverse pregnancy outcomes: a population-based cohort study"],"prefix":"10.1016","volume":"118","author":[{"given":"Maria P.","family":"Velez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Bougie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leah","family":"Bahta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Pudwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Griffiths","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan B.","family":"Brogly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2022.09.015_bib1","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.fertnstert.2011.05.087","article-title":"Incidence of endometriosis by study population and diagnostic method: the ENDO study","volume":"96","author":"Buck Louis","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib2","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s00404-012-2357-8","article-title":"Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress","volume":"286","author":"Augoulea","year":"2012","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0015-0282(97)00191-X","article-title":"Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities","volume":"68","author":"Nisolle","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib4","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/nrendo.2013.255","article-title":"Endometriosis: pathogenesis and treatment","volume":"10","author":"Vercellini","year":"2014","journal-title":"Nat Rev Endocrinology"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib5","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/humupd\/dmz012","article-title":"Reproductive, obstetric, and perinatal outcomes of women with adenomyosis and endometriosis: a systematic review and meta-analysis","volume":"25","author":"Horton","year":"2019","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib6","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1093\/humupd\/dmv045","article-title":"A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and outcomes","volume":"22","author":"Leone Roberti Maggiore","year":"2016","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib7","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.fertnstert.2017.09.028","article-title":"Association between surgically diagnosed endometriosis and adverse pregnancy outcomes","volume":"109","author":"Chen","year":"2018","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib8","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000074815","article-title":"Obstetric outcome in women with endometriosis--a matched case-control study","volume":"56","author":"Kortelahti","year":"2003","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib9","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1093\/humrep\/dem072","article-title":"Endometriosis is associated with a decreased risk of pre-eclampsia","volume":"22","author":"Brosens","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.fertnstert.2008.01.096","article-title":"Preterm birth, ovarian endometriomata, and assisted reproduction technologies","volume":"91","author":"Fernando","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib11","doi-asserted-by":"crossref","first-page":"34","DOI":"10.3109\/09513590.2013.848425","article-title":"A 12-year cohort study on adverse pregnancy outcomes in Eastern Townships of Canada: impact of endometriosis","volume":"30","author":"Aris","year":"2014","journal-title":"Gynecol Endocrinol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib12","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1093\/humrep\/dep123","article-title":"Is there an association between endometriosis and the risk of pre-eclampsia? A population based study","volume":"24","author":"Hadfield","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib13","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1055\/s-0032-1333484","article-title":"Pregnancy outcomes in women with endometriosis","volume":"31","author":"Falconer","year":"2013","journal-title":"Semin Reprod Med"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib14","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.fertnstert.2012.02.024","article-title":"Risks of adverse pregnancy outcome in endometriosis","volume":"98","author":"Brosens","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib15","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1093\/humrep\/dew210","article-title":"Pregnancy outcome in women with endometriosis achieving pregnancy with IVF","volume":"31","author":"Benaglia","year":"2016","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib16","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1097\/AOG.0000000000003410","article-title":"Endometriosis and Risk of adverse pregnancy outcomes","volume":"134","author":"Farland","year":"2019","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib17","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1093\/humrep\/dey269","article-title":"Endometriosis and adverse maternal, fetal and neonatal outcomes, a systematic review and meta-analysis","volume":"33","author":"Lalani","year":"2018","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib18","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.preghy.2018.01.003","article-title":"Systematic review and meta-analysis regarding the association of endometriosis and preeclampsia in women conceiving spontaneously or through assisted reproductive technology","volume":"14","author":"Perez-Lopez","year":"2018","journal-title":"Preg Hypertens"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib19","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s00404-020-05593-4","article-title":"Neonatal outcomes in singleton pregnancies conceived by fresh or frozen embryo transfer compared to spontaneous conceptions: a systematic review and meta-analysis","volume":"302","author":"Elias","year":"2020","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib20","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/s12884-021-03711-x","article-title":"Caesarean section in pregnancies conceived by assisted reproductive technology: a systematic review and meta-analysis","volume":"21","author":"Lodge-Tulloch","year":"2021","journal-title":"BMC Preg Childbirth"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib21","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1186\/s12884-021-03938-8","article-title":"Assisted reproductive technology and hypertensive disorders of pregnancy: systematic review and meta-analyses","volume":"21","author":"Chih","year":"2021","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib22","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1111\/1471-0528.17019","article-title":"Caesarean birth in women with infertility: population-based cohort study","volume":"129","author":"Richmond","year":"2022","journal-title":"Br J Obst Gynaec"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2022.07.028","article-title":"Mode of conception and risk of spontaneous vs. provider-initiated preterm birth: population-based cohort study","author":"Wang","year":"2022","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib24","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1186\/s12913-019-4825-3","article-title":"Data accuracy in the Ontario birth registry: a chart re-abstraction study","volume":"19","author":"Dunn","year":"2019","journal-title":"BMC Health Serv Res"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib25","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.1002\/sim.3697","article-title":"Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples","volume":"28","author":"Austin","year":"2009","journal-title":"Stat Med"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib26","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/aje\/kwh090","article-title":"A modified Poisson regression approach to prospective studies with binary data","volume":"159","author":"Zou","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib27","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/aje\/kwr525","article-title":"A simple unified approach for estimating natural direct and indirect effects","volume":"176","author":"Lange","year":"2012","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib28","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1093\/ije\/dyu149","article-title":"Good practices for quantitative bias analysis","volume":"43","author":"Lash","year":"2014","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib29","unstructured":"Ontario Government. Fact Sheet 9: Ethnic origin and visible minorities,\u00a02022."},{"key":"10.1016\/j.fertnstert.2022.09.015_bib30","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/0002-9378(76)90502-0","article-title":"Endometriosis in the black woman","volume":"125","author":"Chatman","year":"1976","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib31","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s10815-017-0919-1","article-title":"A higher prevalence of endometriosis among Asian women does not contribute to poorer IVF outcomes","volume":"34","author":"Yamamoto","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib32","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/jp.2011.86","article-title":"Racial and ethnic differences in the prevalence of placenta previa","volume":"32","author":"Kim","year":"2012","journal-title":"J Perinatol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib33","first-page":"1","article-title":"Trends and predictors of preterm birth among Asian Americans by ethnicity, 1992-2018","author":"Dongarwar","year":"2021","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib34","doi-asserted-by":"crossref","first-page":"E19","DOI":"10.1503\/cmaj.150464","article-title":"Comparison of black-white disparities in preterm birth between Canada and the United States","volume":"188","author":"McKinnon","year":"2016","journal-title":"Canad Med Assoc J"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib35","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1007\/s40615-021-01057-w","article-title":"Racial and ethnic disparities in cesarean delivery and indications among nulliparous, term, singleton, vertex women","volume":"9","author":"Okwandu","year":"2022","journal-title":"J Racial Ethn Health Disparities"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib36","first-page":"11","article-title":"Maternal race and stillbirth: cohort study and systematic review with meta-analysis","author":"Arechvo","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib37","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.39564","article-title":"Nativity-related disparities in preeclampsia and cardiovascular disease risk among a racially diverse cohort of US women","volume":"4","author":"Boakye","year":"2021","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib38","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1161\/HYPERTENSIONAHA.121.17104","article-title":"Racial disparities in cardiovascular complications with pregnancy-induced hypertension in the United States","volume":"78","author":"Minhas","year":"2021","journal-title":"Hypertension"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib39","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.fertnstert.2017.07.019","article-title":"Endometriosis and obstetrics complications: a systematic review and meta-analysis","volume":"108","author":"Zullo","year":"2017","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib40","doi-asserted-by":"crossref","first-page":"829 e1","DOI":"10.1016\/j.ajog.2021.12.268","article-title":"Pregnancy outcomes among women with endometriosis and fibroids: registry linkage study in Massachusetts","volume":"226","author":"Farland","year":"2022","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib41","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1080\/09513590.2017.1397115","article-title":"Endometriosis and gestational diabetes mellitus risk: a systematic review and meta-analysis","volume":"34","author":"Perez-Lopez","year":"2018","journal-title":"Gynecol Endocrinol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib42","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s13669-020-00281-1","article-title":"Adverse pregnancy outcomes in endometriosis - myths and realities","volume":"9","author":"Farland","year":"2020","journal-title":"Curr Obstet Gynecol Rep"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib43","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1177\/1933719117749760","article-title":"Association between endometriosis and preterm birth in women with spontaneous conception or using assisted reproductive technology: a systematic review and meta-analysis of cohort studies","volume":"25","author":"Perez-Lopez","year":"2018","journal-title":"Reprod Sci"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib44","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph17020401","article-title":"Endometriosis and pregnancy: a single institution experience","volume":"17","author":"Porpora","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib45","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.fertnstert.2016.09.020","article-title":"Endometriosis and pregnancy complications: a Danish cohort study","volume":"107","author":"Glavind","year":"2017","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/oxfordjournals.aje.a116591","article-title":"Toward a clearer definition of confounding","volume":"137","author":"Weinberg","year":"1993","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib47","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1097\/EDE.0b013e3181a819a1","article-title":"Overadjustment bias and unnecessary adjustment in epidemiologic studies","volume":"20","author":"Schisterman","year":"2009","journal-title":"Epidemiology"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib48","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ajog.2010.08.009","article-title":"The \"Great Obstetrical Syndromes\"\u00a0are associated with disorders of deep placentation","volume":"204","author":"Brosens","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib49","article-title":"Estimated reductions in provider-initiated preterm births and hospital length of stay under a universal acetylsalicylic acid prophylaxis strategy: a retrospective cohort study","volume":"5","author":"Ray","year":"2017","journal-title":"Canad Med Assoc J Open"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib50","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.fertnstert.2012.05.031","article-title":"Endometriosis and infertility: a committee opinion","volume":"98","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib51","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1186\/1471-2458-11-450","article-title":"External review and validation of the Swedish national inpatient register","volume":"11","author":"Ludvigsson","year":"2011","journal-title":"BMC Public Health"},{"key":"10.1016\/j.fertnstert.2022.09.015_bib52","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ajog.2021.08.023","article-title":"Administrative health data sets to study endometriosis: a population-based approach","volume":"226","author":"Bougie","year":"2022","journal-title":"Am J Obstet Gynecol"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028222014327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028222014327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T06:17:35Z","timestamp":1762150655000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028222014327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S0015028222014327"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2022.09.015","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.742387733.793597352","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.742387733.793597048","asserted-by":"object"}]},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mode of conception in patients with endometriosis and adverse pregnancy outcomes: a population-based cohort study","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2022.09.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92022 The Authors. Published by Elsevier Inc. on behalf of the American Society for Reproductive Medicine.","name":"copyright","label":"Copyright"}]}}