{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T19:43:11Z","timestamp":1771270991323,"version":"3.50.1"},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.fertnstert.2022.11.018","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T10:57:03Z","timestamp":1669028223000},"page":"444-453","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Antim\u00fcllerian hormone is not associated with embryo ploidy in patients with and without infertility undergoing in\u00a0vitro fertilization with preimplantation genetic testing"],"prefix":"10.1016","volume":"119","author":[{"given":"Yael R.","family":"Stovezky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip A.","family":"Romanski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Bortoletto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven D.","family":"Spandorfer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2022.11.018_bib1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1098\/rspb.1963.0055","article-title":"A quantitative and cytological study of germ cells in human ovaries","volume":"158","author":"Baker","year":"1963","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib2","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1159\/000140595","article-title":"Quantitative morphological investigations of the follicular system in women; variations at different ages","volume":"14","author":"Block","year":"1952","journal-title":"Acta Anat (Basel)"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib3","first-page":"165","article-title":"The effect of maternal age on the frequency of trisomy: change in meiosis or in utero selection?","volume":"311","author":"Warburton","year":"1989","journal-title":"Prog Clin Biol Res"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib4","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1210\/er.2009-0006","article-title":"Ovarian aging: mechanisms and clinical consequences","volume":"30","author":"Broekmans","year":"2009","journal-title":"Endocr Rev"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12916-016-0699-y","article-title":"Back to the basics of ovarian aging: a population-based study on longitudinal antim\u00fcllerian hormone decline","volume":"14","author":"de Kat","year":"2016","journal-title":"BMC Med"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib6","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.fertnstert.2011.10.031","article-title":"A characterization of the relationship of ovarian reserve markers with age","volume":"97","author":"Rosen","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2011.01.151","article-title":"A lower antral follicle count is associated with infertility","volume":"95","author":"Rosen","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib8","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.fertnstert.2020.08.028","article-title":"AMH highly correlates with assisted reproduction cumulative live birth rate in women with dimished ovarian reserve independent of age: an analysis of 34,540 cycles from the SART database for 2014-2016","volume":"114","author":"Tal","year":"2020","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib9","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1093\/humrep\/dep404","article-title":"A reduced size of the ovarian follicle pool is associated with an increased risk of a trisomic pregnancy in IVF-treated women","volume":"25","author":"Haadsma","year":"2010","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib10","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.fertnstert.2011.07.1149","article-title":"Early menopause in mothers of children with Down syndrome?","volume":"96","author":"van der Stroom","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib11","doi-asserted-by":"crossref","first-page":"494","DOI":"10.5468\/ogs.2015.58.6.494","article-title":"Maternal antim\u00fcllerian hormone as a predictor of fetal aneuploidy occurring in an early pregnancy loss","volume":"58","author":"Shim","year":"2015","journal-title":"Obstet Gynecol Sci"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib12","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.fertnstert.2018.01.039","article-title":"Antim\u00fcllerian hormone as a risk factor for miscarriage in naturally conceived pregnancies","volume":"109","author":"Lyttle Schumacher","year":"2018","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib13","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1093\/humrep\/dew032","article-title":"Infertile women below the age of 40 have similar antim\u00fcllerian hormone levels and antral follicle count compared with women of the same age with no history of infertility","volume":"31","author":"Hvidman","year":"2016","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib14","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1001\/jama.2017.14588","article-title":"Association between biomarkers of ovarian reserve and infertility among older women of reproductive age","volume":"318","author":"Steiner","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib15","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/j.fertnstert.2012.08.008","article-title":"Low concentration of circulating antim\u00fcllerian hormone is not predictive of reduced fecundability in young healthy women: a prospective cohort study","volume":"98","author":"Hagen","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib16","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1016\/j.fertnstert.2015.12.003","article-title":"Antim\u00fcllerian hormone and pregnancy loss from the Effects of Aspirin in Gestation and Reproduction trial","volume":"105","author":"Zarek","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib17","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1093\/humrep\/der091","article-title":"Trisomic pregnancy and elevated FSH: implications for the oocyte pool hypothesis","volume":"26","author":"Kline","year":"2011","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib18","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.fertnstert.2016.06.016","article-title":"Higher rates of aneuploidy in blastocysts and higher risk of no embryo transfer in recurrent pregnancy loss patients with diminished ovarian reserve undergoing in\u00a0vitro fertilization","volume":"106","author":"Shahine","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib19","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1093\/humrep\/dey238","article-title":"Diminished ovarian reserve and poor response to stimulation in patients <38 years old: a quantitative but not qualitative reduction in performance","volume":"33","author":"Morin","year":"2018","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib20","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.fertnstert.2017.08.029","article-title":"Female age, serum antim\u00fcllerian hormone level, and number of oocytes affect the rate and number of euploid blastocysts in in\u00a0vitro fertilization\/intracytoplasmic sperm injection cycles","volume":"108","author":"La Marca","year":"2017","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib21","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.rbmo.2017.06.027","article-title":"Significant correlation between antim\u00fcllerian hormone and embryo euploidy in a subpopulation of infertile patients","volume":"35","author":"Gat","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib22","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.rbmo.2018.04.039","article-title":"Low antim\u00fcllerian hormone concentration is associated with increased risk of embryonic aneuploidy in women of advanced age","volume":"37","author":"Jiang","year":"2018","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib23","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s10815-021-02365-0","article-title":"Embryo attrition in planned PGT-A: predicting the number of available blastocysts for transfer","volume":"39","author":"Gordon","year":"2022","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib24","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.rbmo.2021.03.006","article-title":"Serum antim\u00fcllerian hormone levels are not associated with aneuploidy rates in human blastocysts","volume":"42","author":"Pipari","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib25","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.fertnstert.2020.10.051","article-title":"Diminished ovarian reserve is associated with reduced euploid rates via preimplantation genetic testing for aneuploidy independently from age: evidence for concomitant reduction in oocyte quality with quantity","volume":"115","author":"Jaswa","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib26","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1093\/humrep\/der092","article-title":"ESHRE consensus on the definition of \u201cpoor response\u201d to ovarian stimulation for in\u00a0vitro fertilization: the Bologna criteria","volume":"26","author":"Ferraretti","year":"2011","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib27","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.fertnstert.2010.10.011","article-title":"Age-specific serum antim\u00fcllerian hormone values for 17,120 women presenting to fertility centers within the United States","volume":"95","author":"Seifer","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib28","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1093\/humrep\/deh668","article-title":"GnRH antagonist versus long GnRH agonist protocol in poor responders undergoing IVF: a randomized controlled trial","volume":"20","author":"Cheung","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib29","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0015-0282(16)55264-9","article-title":"Randomized, prospective comparison of luteal leuprolide acetate and gonadotropins versus clomiphene citrate and gonadotropins in 408 first cycles of in\u00a0vitro fertilization","volume":"58","author":"Tummon","year":"1992","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib30","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.fertnstert.2008.04.057","article-title":"Antagonist\/letrozole protocol in poor ovarian responders for intracytoplasmic sperm injection: a comparative study with the microdose flare-up protocol","volume":"92","author":"Yarali","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib31","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0015-0282(97)00575-X","article-title":"Clinical and endocrine effects of a microdose GnRH agonist flare regimen administered to poor responders who are undergoing in\u00a0vitro fertilization","volume":"69","author":"Surrey","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib32","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.fertnstert.2005.04.031","article-title":"Use of a luteal estradiol patch and a gonadotropin-releasing hormone antagonist suppression protocol before gonadotropin stimulation for in\u00a0vitro fertilization in poor responders","volume":"84","author":"Dragisic","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0176019","article-title":"Sliding scale HCG trigger yields equivalent pregnancy outcomes and reduces ovarian hyperstimulation syndrome: analysis of 10,427 IVF-ICSI cycles","volume":"12","author":"Gunnala","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib34","series-title":"An atlas of human blastocyts","author":"Veeck","year":"2003"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib35","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.theriogenology.2006.09.014","article-title":"Highly efficient vitrification for cryopreservation of human oocytes and embryos: the Cryotop method","volume":"67","author":"Kuwayama","year":"2007","journal-title":"Theriogenology"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib36","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.fertnstert.2021.02.029","article-title":"Body mass index is not associated with embryo ploidy in patients undergoing in\u00a0vitro fertilization with preimplantation genetic testing","volume":"116","author":"Stovezky","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib37","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.fertnstert.2013.11.004","article-title":"The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening","volume":"101","author":"Franasiak","year":"2014","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib38","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1477-7827-10-48","article-title":"Lessons from elective in\u00a0vitro fertilization (IVF) in, principally, non-infertile women","volume":"10","author":"Gleicher","year":"2012","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib39","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1530\/REP-19-0330","article-title":"Inflammaging is associated with shifted macrophage ontogeny and polarization in the aging mouse ovary","volume":"159","author":"Zhang","year":"2020","journal-title":"Reproduction"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib40","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/s41598-020-79488-4","article-title":"Evaluation of inflammation and follicle depletion during ovarian ageing in mice","volume":"11","author":"Lliberos","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib41","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.713650","article-title":"The role of T cells in ovarian physiology and infertility","volume":"10","author":"Knapik","year":"2022","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib42","doi-asserted-by":"crossref","first-page":"R79","DOI":"10.1530\/REP-18-0583","article-title":"Obesity induces ovarian inflammation and reduces oocyte quality","volume":"158","author":"Snider","year":"2019","journal-title":"Reproduction"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.beem.2019.101323","article-title":"Insights into the autoimmune aspect of premature ovarian insufficiency","volume":"33","author":"Sharif","year":"2019","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2022.11.018_bib44","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.fertnstert.2016.01.040","article-title":"Validation of a next-generation sequencing-based protocol for 24-chromosome aneuploidy screening of blastocysts","volume":"105","author":"Huang","year":"2016","journal-title":"Fertil Steril"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028222020453?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028222020453?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:38:58Z","timestamp":1758011938000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028222020453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S0015028222020453"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2022.11.018","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antim\u00fcllerian hormone is not associated with embryo ploidy in patients with and without infertility undergoing in\u00a0vitro fertilization with preimplantation genetic testing","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2022.11.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92022 Published by Elsevier Inc. on behalf of the American Society for Reproductive Medicine","name":"copyright","label":"Copyright"}]}}