{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T21:37:56Z","timestamp":1782855476840,"version":"3.54.5"},"reference-count":20,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.fertnstert.2023.08.953","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T01:49:06Z","timestamp":1693187346000},"page":"1220-1226","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Euploid programmed frozen embryo transfer cycles are associated with a higher live birth rate when estradiol levels more closely mimic physiology"],"prefix":"10.1016","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6652-1760","authenticated-orcid":false,"given":"Nina","family":"Vyas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nissiya","family":"Adjei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Spandorfer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2023.08.953_bib2","first-page":"CD003414","article-title":"Cycle regimens for frozen-thawed embryo transfer","volume":"7","author":"Ghobara","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib3","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.fertnstert.2018.05.013","article-title":"Impact of method of endometrial preparation for frozen blastocyst transfer on pregnancy outcome: a retrospective cohort study","volume":"110","author":"Alur-Gupta","year":"2018","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib4","first-page":"85","article-title":"Hormonal replacement treatment improves clinical pregnancy in frozen-thawed embryos transfer cycles: a retrospective cohort study","volume":"6","author":"Zheng","year":"2013","journal-title":"Am J Transl Res"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib5","article-title":"Estrogen receptor function: impact on the human endometrium","volume":"13","author":"Yu","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib6","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1210\/jcem-57-4-792","article-title":"Hormonal dynamics at midcycle: a reevaluation","volume":"57","author":"Hoff","year":"1983","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib7","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.placenta.2005.04.005","article-title":"Suppression of extravillous trophoblast invasion of uterine spiral arteries by estrogen during early baboon pregnancy","volume":"27","author":"Albrecht","year":"2006","journal-title":"Placenta"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib8","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1007\/s10815-017-0983-6","article-title":"Replacing\u00a0single frozen-thawed euploid embryos in a natural cycle in ovulatory\u00a0women may increase live birth rates compared to medicated cycles\u00a0in anovulatory women","volume":"34","author":"Melnick","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib9","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1007\/s10815-022-02521-0","article-title":"Association between serum estradiol level on day of progesterone start and outcomes from frozen blastocyst transfer cycles utilizing oral estradiol","volume":"39","author":"Goldman","year":"2022","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib10","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.fertnstert.2016.11.012","article-title":"Morphologic grading of euploid blastocysts influences implantation and ongoing pregnancy rates","volume":"107","author":"Irani","year":"2017","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib11","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/978-1-4939-0659-8_8","article-title":"Assisted reproductive techniques","volume":"1154","author":"Huang","year":"2014","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib12","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0015-0282(00)00518-5","article-title":"Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer","volume":"73","author":"Gardner","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib13","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1093\/oxfordjournals.aje.a115101","article-title":"The impact of confounder selection criteria on effect estimation","volume":"129","author":"Mickey","year":"1989","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib14","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1093\/humrep\/deaa051","article-title":"Confounding and effect measure modification in reproductive medicine research","volume":"35","author":"Correia","year":"2020","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib15","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1007\/s10815-017-1016-1","article-title":"Elevated serum estradiol levels in artificial autologous frozen embryo transfer cycles negatively impact ongoing pregnancy and live birth rates","volume":"34","author":"Fritz","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib21","doi-asserted-by":"crossref","first-page":"5592","DOI":"10.1038\/s41598-022-09545-7","article-title":"Elevated estradiol levels in frozen embryo transfer have different effects on pregnancy outcomes depending on the stage of transferred embryos","volume":"12","author":"Li","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib16","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1126\/science.1071601","article-title":"Deciphering the cross-talk of implantation: advances and challenges","volume":"296","author":"Paria","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib17","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0002-9378(00)70235-3","article-title":"The role of estrogen in the maintenance of primate pregnancy","volume":"182","author":"Albrecht","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib18","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1093\/oxfordjournals.humrep.a136313","article-title":"Implantation: clinical evidence for a detrimental effect on uterine receptivity of high serum oestradiol concentrations in high and normal responder patients","volume":"10","author":"Sim\u00f3n","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib19","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0015-0282(16)59661-7","article-title":"Evidence for an adverse effect of elevated serum estradiol concentrations on embryo implantation","volume":"49","author":"Forman","year":"1988","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2023.08.953_bib20","first-page":"463","article-title":"High peak estradiol predicts higher miscarriage and lower live birth rates in high responders triggered with a GnRH agonist in IVF\/ICSI cycles","volume":"60","author":"Steward","year":"2015","journal-title":"J Reprod Med"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028223017211?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028223017211?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:41:15Z","timestamp":1758012075000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028223017211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S0015028223017211"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2023.08.953","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Euploid programmed frozen embryo transfer cycles are associated with a higher live birth rate when estradiol levels more closely mimic physiology","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2023.08.953","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92023 American Society for Reproductive Medicine, Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}