{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T04:49:27Z","timestamp":1782190167078,"version":"3.54.5"},"reference-count":38,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T00:00:00Z","timestamp":1766016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.fertnstert.2025.12.015","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T16:14:34Z","timestamp":1766420074000},"page":"852-859","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Recurrent pregnancy loss and the role of Mycoplasma and Ureaplasma: a prospective cohort study with outcome after treatment"],"prefix":"10.1016","volume":"125","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8341-5448","authenticated-orcid":false,"given":"Sierra","family":"Bishop","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Truong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Jaslow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6049-3842","authenticated-orcid":false,"given":"William","family":"Kutteh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2025.12.015_bib1","doi-asserted-by":"crossref","first-page":"4074","DOI":"10.3390\/jcm12124074","article-title":"Recurrent pregnancy loss etiology, risk factors, diagnosis, and management. fresh look into a full box","volume":"12","author":"Turesheva","year":"2023","journal-title":"J Clin Med"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib2","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0140-6736(90)92159-F","article-title":"Recurrent miscarriage I: definition and epidemiology","volume":"336","author":"Stirrat","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib3","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.fertnstert.2012.06.048","article-title":"Evaluation and treatment of recurrent pregnancy loss: a committee opinion","volume":"98","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib4","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.fertnstert.2009.01.166","article-title":"Diagnostic factors identified in 1020 women with two versus three or more recurrent pregnancy losses","volume":"93","author":"Jaslow","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib5","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.fertnstert.2013.12.031","article-title":"Chronic endometritis in women with recurrent early pregnancy loss and\/or fetal demise","volume":"101","author":"McQueen","year":"2014","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib6","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1177\/1933719113508817","article-title":"Chronic endometritis due to common bacteria is prevalent in women with recurrent miscarriage as confirmed by improved pregnancy outcome after antibiotic treatment","volume":"21","author":"Cicinelli","year":"2014","journal-title":"Reprod Sci"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1427454","article-title":"Chronic endometritis and recurrent reproductive failure: a systematic review and meta-analysis","volume":"15","author":"Ticconi","year":"2024","journal-title":"Front Immunol"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib8","doi-asserted-by":"crossref","first-page":"602.e1","DOI":"10.1016\/j.ajog.2018.02.012","article-title":"The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology","volume":"218","author":"Moreno","year":"2018","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib9","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.fertnstert.2021.04.036","article-title":"Redefining chronic endometritis: the importance of endometrial stromal changes","volume":"116","author":"McQueen","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib10","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.fertnstert.2018.04.012","article-title":"Endometritis: new time, new concepts","volume":"110","author":"Kitaya","year":"2018","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib11","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.rbmo.2021.02.003","article-title":"Impact of chronic endometritis in infertility: a SWOT analysis","volume":"42","author":"Espin\u00f3s","year":"2021","journal-title":"Reprod BioMed Online"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib12","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.ogc.2014.08.010","article-title":"The role of Mycoplasma and Ureaplasma in adverse pregnancy outcomes","volume":"41","author":"Murtha","year":"2014","journal-title":"Obstet Gynecol Clin North Am"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib13","article-title":"Adverse pregnancy and birth outcomes associated with Mycoplasma hominis, Ureaplasma urealyticum and Ureaplasma parvum: a systematic review and meta-analysis","volume":"12","author":"Jonduo","year":"2022","journal-title":"Br Med J Open"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib14","first-page":"329","article-title":"Infectious agents in tissues from spontaneous abortions in the first trimester of pregnancy","volume":"26","author":"Penta","year":"2003","journal-title":"New Microbiol"},{"issue":"43","key":"10.1016\/j.fertnstert.2025.12.015_bib15","first-page":"e1","article-title":"The Alabama preterm birth study: umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants","volume":"198","author":"Goldenberg","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib16","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.3855\/jidc.15134","article-title":"Is there an association between recurrent spontaneous abortion and mycoplasma infection?","volume":"16","author":"Yu","year":"2022","journal-title":"J Infect Dev Ctries"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib17","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/S0002-9378(96)70610-5","article-title":"Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone","volume":"174","author":"Kutteh","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib18","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1016\/j.fertnstert.2013.01.152","article-title":"Effect of prior birth and miscarriage frequency on the prevalence of acquired and congenital uterine anomalies in women with recurrent miscarriage: a cross-sectional study","volume":"99","author":"Jaslow","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib19","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1128\/jcm.16.4.709-714.1982","article-title":"Comparative evaluation of media for isolation of Ureaplasma urealyticum and genital mycoplasma species","volume":"16","author":"Leland","year":"1982","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib20","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1001\/jama.2022.1246","article-title":"CDC sexually transmitted infections treatment guidelines, 2021","volume":"327","author":"Hazra","year":"2022","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib21","first-page":"1","article-title":"Sexually transmitted diseases treatment guidelines, 2015","volume":"64","author":"Workowski","year":"2015","journal-title":"MMWR Recomm Rep"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib22","first-page":"538","article-title":"Endometritis-diagnosis, treatment and its impact on fertility-a scoping review","volume":"26","author":"Singh","year":"2022","journal-title":"JBRA Assist Reprod"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib23","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.fertnstert.2015.06.044","article-title":"Pregnancy outcomes in women with chronic endometritis and recurrent pregnancy loss","volume":"104","author":"McQueen","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib24","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0002-9378(83)90499-4","article-title":"Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas","volume":"145","author":"Quinn","year":"1983","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib25","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.fertnstert.2018.01.022","article-title":"Comparison of the prevalence of chronic endometritis as determined by means of different diagnostic methods in women with and without reproductive failure","volume":"109","author":"Liu","year":"2018","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib26","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.fertnstert.2019.03.004","article-title":"Unified diagnostic criteria for chronic endometritis at fluid hysteroscopy: proposal and reliability evaluation through an international randomized-controlled observer study","volume":"112","author":"Cicinelli","year":"2019","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib27","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ajog.2025.03.005","article-title":"Hysteroscopic criteria for the diagnosis of chronic endometritis: a systematic review and diagnostic test accuracy meta-analysis","volume":"233","author":"Riemma","year":"2025","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib28","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.fertnstert.2018.12.007","article-title":"Correlation between hysteroscopy findings and chronic endometritis","volume":"111","author":"Song","year":"2019","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib29","doi-asserted-by":"crossref","first-page":"485","DOI":"10.3892\/etm.2012.824","article-title":"Inter-observer and intra-observer variability in immunohistochemical detection of endometrial stromal plasmacytes in chronic endometritis","volume":"5","author":"Kitaya","year":"2013","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib30","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.fertnstert.2007.03.074","article-title":"Chronic endometritis: correlation among hysteroscopic, histologic, and bacteriologic findings in a prospective trial with 2190 consecutive office hysteroscopies","volume":"89","author":"Cicinelli","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40168-021-01184-w","article-title":"Endometrial microbiota composition is associated with reproductive outcome in infertile patients","volume":"10","author":"Moreno","year":"2022","journal-title":"Microbiome"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib32","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.5858\/2004-128-1000-RSIAIT","article-title":"Routine syndecan-1 immunohistochemistry aids in the diagnosis of chronic endometritis","volume":"128","author":"Bayer-Gamer","year":"2004","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.xfnr.2024.100073","article-title":"Unveiling the silver lining: a narrative review of clinical evaluation and management of chronic endometritis and its impact on fertility","volume":"5","author":"Strug","year":"2024","journal-title":"F&S Reviews"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib34","series-title":"Blaustein\u2019s pathology of the female genital tract","first-page":"305","article-title":"Benign diseases of the endometrium","author":"McCluggage","year":"2011"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib35","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0015-0282(16)53636-X","article-title":"Secretory immune system of the female reproductive tract. II. Local immune system in normal and infected fallopian tube","volume":"54","author":"Kutteh","year":"1990","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib36","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/humrep\/der341","article-title":"The reliability of the histological diagnosis of endometritis in asymptomatic IVF cases: a multicenter observer study","volume":"27","author":"Kasius","year":"2012","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib38","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1159\/000223819","article-title":"Poor reliability of vaginal and endocervical cultures for evaluating microbiology of endometrial cavity in women with chronic endometritis","volume":"68","author":"Cicinelli","year":"2009","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.fertnstert.2025.12.015_bib39","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1136\/sextrans-2017-053384","article-title":"Prevalence of Mycoplasma genitalium in different population groups: systematic review and meta-analysis","volume":"94","author":"Baumann","year":"2018","journal-title":"Sex Transm Infect"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028225023027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028225023027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T09:49:19Z","timestamp":1778924959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028225023027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S0015028225023027"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2025.12.015","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recurrent pregnancy loss and the role of Mycoplasma and Ureaplasma: a prospective cohort study with outcome after treatment","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2025.12.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92025 The Authors. Published by Elsevier Inc. on behalf of the American Society for Reproductive Medicine.","name":"copyright","label":"Copyright"}]}}