{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T01:02:38Z","timestamp":1784768558671,"version":"3.55.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.fertnstert.2026.03.034","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T01:43:45Z","timestamp":1775180625000},"page":"67-74","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Congenital heart disease in a singleton pregnancy conceived through assisted reproductive technology"],"prefix":"10.1016","volume":"126","author":[{"given":"Ho Yeon","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Hoon","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon-Cheol","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Jeong","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geum Joon","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2026.03.034_bib1","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.fertnstert.2012.05.019","article-title":"Obstetric and perinatal outcomes in singleton pregnancies resulting from the transfer of frozen thawed versus fresh embryos generated through in vitro fertilization treatment: a systematic review and meta-analysis","volume":"98","author":"Maheshwari","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib2","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00404-017-4291-2","article-title":"Worldwide prevalence of adverse pregnancy outcomes associated with in vitro fertilization\/intracytoplasmic sperm injection among multiple births: a systematic review and meta-analysis based on cohort studies","volume":"295","author":"Qin","year":"2017","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib3","doi-asserted-by":"crossref","first-page":"4840","DOI":"10.1093\/eurheartj\/ehae572","article-title":"Congenital heart defects in children born after assisted reproductive technology: a CoNARTaS study","volume":"45","author":"Sargisian","year":"2024","journal-title":"Eur Heart J"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib4","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1097\/AOG.0b013e318269c282","article-title":"Assisted reproductive technology and major birth defects in Western Australia","volume":"120","author":"Hansen","year":"2012","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib5","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1093\/humupd\/dmt006","article-title":"Assisted reproductive technology and birth defects: a systematic review and meta-analysis","volume":"19","author":"Hansen","year":"2013","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib6","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/humupd\/dms018","article-title":"Obstetric and perinatal outcomes in singleton pregnancies resulting from IVF\/ICSI: a systematic review and meta-analysis","volume":"18","author":"Pandey","year":"2012","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib7","doi-asserted-by":"crossref","first-page":"2674","DOI":"10.1016\/j.fertnstert.2010.02.043","article-title":"Adverse obstetric and perinatal outcomes in subfertile women conceiving without assisted reproductive technologies","volume":"94","author":"Jaques","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib8","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.fertnstert.2012.02.053","article-title":"Birth defects in children conceived by in vitro fertilization and intracytoplasmic sperm injection: a meta-analysis","volume":"97","author":"Wen","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib9","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/uog.18932","article-title":"Congenital heart defects in IVF\/ICSI pregnancy: systematic review and meta-analysis","volume":"51","author":"Giorgione","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib10","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3961\/jpmph.16.122","article-title":"Congenital malformations in infants of mothers undergoing assisted reproductive technologies: a systematic review and meta-analysis study","volume":"50","author":"Hoorsan","year":"2017","journal-title":"J Prev Med Public Health"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib11","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1001\/jamapediatrics.2019.6096","article-title":"Associations of assisted reproductive technology and twin pregnancy with risk of congenital heart defects","volume":"174","author":"Wen","year":"2020","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib12","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.earlhumdev.2005.07.005","article-title":"Prenatal stress, the hypothalamic-pituitary-adrenal axis, and fetal and infant neurobehaviour","volume":"81","author":"Austin","year":"2005","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib13","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jad.2021.05.002","article-title":"Maternal psychological stress during pregnancy and risk of congenital heart disease in offspring: a systematic review and meta-analysis","volume":"291","author":"Gu","year":"2021","journal-title":"J Affect Disord"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib14","doi-asserted-by":"crossref","first-page":"e1225","DOI":"10.1542\/peds.2012-3024","article-title":"Prenatal maternal bereavement and congenital heart defects in offspring: a registry-based study","volume":"131","author":"Zhu","year":"2013","journal-title":"Pediatrics"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2025.105736","article-title":"Rare damaging variants in the sex differences of congenital heart disease: an exome sequencing study","volume":"116","author":"Sun","year":"2025","journal-title":"EBioMedicine"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib16","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1093\/humrep\/dex234","article-title":"The international glossary on infertility and fertility care, 2017","volume":"32","author":"Zegers-Hochschild","year":"2017","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib17","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1002\/ajmg.a.38237","article-title":"Recurrence of congenital heart defects among siblings-a nationwide study","volume":"173","author":"Brodwall","year":"2017","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib18","article-title":"Birth defects surveillance after assisted reproductive technology in Beijing: a whole of population-based cohort study","volume":"11","author":"Zhang","year":"2021","journal-title":"BMJ Open"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib19","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.fertnstert.2021.04.035","article-title":"Utility of routine screening fetal echocardiogram in pregnancies conceived by in vitro fertilization","volume":"116","author":"Bjorkman","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib20","doi-asserted-by":"crossref","first-page":"5630","DOI":"10.3390\/jcm10235630","article-title":"Risk assessment of the increased occurrence of congenital cardiac and non-cardiac defects in fetuses with a normal karyotype after assisted fertilization in comparison to natural fertilization based on ultrasound diagnostics","volume":"10","author":"Serafin","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib21","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/pd.4327","article-title":"Comparison of method of conception in fetuses undergoing echocardiography at a tertiary referral center","volume":"34","author":"Votava-Smith","year":"2014","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib22","doi-asserted-by":"crossref","first-page":"2896","DOI":"10.1007\/s43032-023-01252-6","article-title":"Assisted reproductive techniques and risk of congenital heart diseases in children: a systematic review and meta-analysis","volume":"30","author":"Gullo","year":"2023","journal-title":"Reprod Sci"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib23","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.3390\/medicina60081373","article-title":"Fresh versus Frozen embryo transfer in in vitro fertilization\/intracytoplasmic sperm injection cycles: a systematic review and meta-analysis of neonatal outcomes","volume":"60","author":"Tocariu","year":"2024","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib24","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1016\/S0140-6736(18)32843-5","article-title":"Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial","volume":"393","author":"Wei","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib25","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/uog.17527","article-title":"Fetal cardiac remodeling in twin pregnancy conceived by assisted reproductive technology","volume":"51","author":"Valenzuela-Alcaraz","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib26","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1093\/eurheartj\/ehv145","article-title":"Cardiovascular dysfunction in children conceived by assisted reproductive technologies","volume":"36","author":"Scherrer","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib27","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1146\/annurev-physiol-020911-153245","article-title":"Fetal programming and metabolic syndrome","volume":"74","author":"Rinaudo","year":"2012","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib28","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1002\/pd.5770","article-title":"Adverse perinatal outcome and placental abnormalities in pregnancies with major fetal congenital heart defects: a retrospective case-control study","volume":"40","author":"Giorgione","year":"2020","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib29","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1159\/000493938","article-title":"Prenatal growth in fetuses with isolated cyanotic and non-cyanotic congenital heart defects","volume":"47","author":"Inversetti","year":"2020","journal-title":"Fetal Diagn Ther"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib30","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1002\/pd.5052","article-title":"Nuchal translucency measurement, free beta-hCG and PAPP-A concentrations in IVF\/ICSI pregnancies: systematic review and meta-analysis","volume":"37","author":"Cavoretto","year":"2017","journal-title":"Prenat Diagn"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib31","doi-asserted-by":"crossref","first-page":"629","DOI":"10.3389\/fphys.2018.00629","article-title":"Near to one\u2019s heart: the intimate relationship between the placenta and fetal heart","volume":"9","author":"Camm","year":"2018","journal-title":"Front Physiol"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib32","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.placenta.2021.07.297","article-title":"Placenta morphology and biomarkers in pregnancies with congenital heart disease - a systematic review","volume":"112","author":"Snoep","year":"2021","journal-title":"Placenta"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib33","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1161\/CIRCULATIONAHA.106.685859","article-title":"Gender differences in the treatment for acute myocardial infarction: bias or biology?","volume":"115","author":"Anderson","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib34","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1161\/CIRCULATIONAHA.107.758086","article-title":"Gender and outcome in adult congenital heart disease","volume":"118","author":"Verheugt","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.fertnstert.2026.03.034_bib35","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.pedneo.2012.11.010","article-title":"Prevalence, mortality, and the disease burden of pediatric congenital heart disease in Taiwan","volume":"54","author":"Yeh","year":"2013","journal-title":"Pediatr Neonatol"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028226001871?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028226001871?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:39:40Z","timestamp":1784767180000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028226001871"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0015028226001871"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2026.03.034","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Congenital heart disease in a singleton pregnancy conceived through assisted reproductive technology","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2026.03.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92026 American Society for Reproductive Medicine, Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}