{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T20:26:06Z","timestamp":1793910366551,"version":"4.8.0"},"reference-count":46,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.fertnstert.2026.04.016","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:07:18Z","timestamp":1777561638000},"page":"265-274","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Obesity is associated with an increased risk of early pregnancy loss after euploid frozen embryo transfer"],"prefix":"10.1016","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6373-1746","authenticated-orcid":false,"given":"Christine","family":"Whitehead","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin","family":"Lefebvre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emre","family":"Seli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2026.04.016_bib1","series-title":"Obesity and severe obesity prevalence in adults: United States, August 2021-August 2023","author":"Emmerich","year":"2024"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib2","series-title":"Obesity among women of childbearing age: United States, 2012\u20132023","year":"2025"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib3","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/j.fertnstert.2021.08.018","article-title":"Obesity and reproduction: a committee opinion","volume":"116","author":"Penzias","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib4","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1093\/biolre\/ioab228","article-title":"Obesity and oocyte quality: significant implications for ART and emerging mechanistic insights","volume":"106","author":"Gonzalez","year":"2022","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib5","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.fertnstert.2023.07.027","article-title":"Frozen embryo transfer outcomes decline with increasing female body mass index in female but not male factor infertility: analysis of 56,564 euploid blastocyst transfers","volume":"121","author":"Bakkensen","year":"2024","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib6","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.fertnstert.2023.11.005","article-title":"Higher live birth rates are associated with a normal body mass index in preimplantation genetic testing for aneuploidy frozen embryo transfer cycles: a Society for Assisted Reproductive Technology Clinic Outcome Reporting System study","volume":"121","author":"Peterson","year":"2024","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib7","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.fertnstert.2025.07.022","article-title":"The reproductive journey of women with obesity undergoing assisted reproductive technology: an analysis of 48,595 in vitro fertilization cycles in 31,829 women","volume":"124","author":"Bellver","year":"2025","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib8","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.fertnstert.2020.12.037","article-title":"The Appraisal of Body Content (ABC) trial: increased male or female adiposity does not significantly impact in vitro fertilization laboratory or clinical outcomes","volume":"116","author":"Kim","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib9","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1093\/humrep\/det292","article-title":"IVF outcomes in obese donor oocyte recipients: a systematic review and meta-analysis","volume":"28","author":"Jungheim","year":"2013","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib10","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.fertnstert.2013.06.001","article-title":"Obesity reduces uterine receptivity: clinical experience from 9,587 first cycles of ovum donation with normal weight donors","volume":"100","author":"Bellver","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib11","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.fertnstert.2015.10.015","article-title":"Pregnancy outcomes decline with increasing recipient body mass index: an analysis of 22,317 fresh donor\/recipient cycles from the 2008\u20132010 Society for Assisted Reproductive Technology Clinic Outcome Reporting System registry","volume":"105","author":"Provost","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib13","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1089\/jwh.2021.0433","article-title":"Elevated body mass index in donor oocyte recipients does not affect implantation of euploid embryos","volume":"31","author":"Moreta","year":"2022","journal-title":"J Womens Health (Larchmt)"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib14","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.fertnstert.2023.07.029","article-title":"Association between oocyte donors' or recipients' body mass index and clinical outcomes after first single blastocyst transfers-the uterus is the most affected","volume":"121","author":"Fabozzi","year":"2024","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib12","first-page":"394","article-title":"Overweight and obesity significantly reduce pregnancy, implantation, and live birth rates in women undergoing in vitro fertilization procedures","volume":"25","author":"Garc\u00eda-Ferreyra","year":"2021","journal-title":"JBRA Assist Reprod"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib15","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.rbmo.2021.07.006","article-title":"Maternal body mass index associates with blastocyst euploidy and live birth rates: the tip of an iceberg?","volume":"43","author":"Fabozzi","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib16","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1093\/humrep\/deaa010","article-title":"Female obesity does not impact live birth rate after frozen-thawed blastocyst transfer","volume":"35","author":"Prost","year":"2020","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib17","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/humupd\/dmz011","article-title":"Female obesity is negatively associated with live birth rate following IVF: a systematic review and meta-analysis","volume":"25","author":"Sermondade","year":"2019","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib18","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph182413143","article-title":"Psychosocial aspects of gestational grief in women undergoing infertility treatment: a systematic review of qualitative and quantitative evidence","volume":"18","author":"de Castro","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib19","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.fertnstert.2020.07.052","article-title":"A multicenter, prospective, blinded, nonselection study evaluating the predictive value of an aneuploid diagnosis using a targeted next-generation sequencing\u2013based preimplantation genetic testing for aneuploidy assay and impact of biopsy","volume":"115","author":"Tiegs","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib20","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.fertnstert.2013.02.056","article-title":"In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial","volume":"100","author":"Forman","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib21","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/s41586-025-09964-2","article-title":"Common variation in meiosis genes shapes human recombination and aneuploidy","volume":"651","author":"Carioscia","year":"2026","journal-title":"Nature"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib22","doi-asserted-by":"crossref","DOI":"10.1093\/aje\/kwaf232","article-title":"Choosing between modified Poisson and log-binomial regression: evidence for the superiority of modified Poisson regression under heterogeneous risk ratios","author":"Sawada","year":"2025","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib23","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s10815-013-9932-1","article-title":"The simplified SART embryo scoring system is highly correlated to implantation and live birth in single blastocyst transfers","volume":"30","author":"Heitmann","year":"2013","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib24","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.fertnstert.2020.09.139","article-title":"Female obesity increases the risk of miscarriage of euploid embryos","volume":"115","author":"Cozzolino","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib25","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.rbmo.2016.09.011","article-title":"Increased miscarriage of euploid pregnancies in obese women undergoing cryopreserved embryo transfer","volume":"34","author":"Tremellen","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib26","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.fertnstert.2017.08.024","article-title":"Neutral effect of body mass index on implantation rate after frozen-thawed blastocyst transfer","volume":"108","author":"Insogna","year":"2017","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2019.05.043","article-title":"The combined impact of maternal age and body mass index on cumulative live birth following in vitro fertilization","volume":"221","author":"Goldman","year":"2019","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.rbmo.2024.104074","article-title":"Ongoing pregnancy rates in single euploid frozen embryo transfers remain unaffected by female age: a retrospective study","volume":"49","author":"Lawrenz","year":"2024","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib29","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/j.fertnstert.2008.07.1732","article-title":"Point of failure as a predictor of in vitro fertilization treatment discontinuation","volume":"91","author":"Pearson","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib30","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.fertnstert.2006.11.162","article-title":"Obesity and poor reproductive outcome: the potential role of the endometrium","volume":"88","author":"Bellver","year":"2007","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib31","doi-asserted-by":"crossref","first-page":"j1","DOI":"10.1136\/bmj.j1","article-title":"Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child","volume":"356","author":"Catalano","year":"2017","journal-title":"Br Med J"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib32","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1093\/humrep\/dew048","article-title":"Diet-induced obesity impairs endometrial stromal cell decidualization: a potential role for impaired autophagy","volume":"31","author":"Rhee","year":"2016","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib33","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1093\/humrep\/deac003","article-title":"Impact of uterine malformations on pregnancy and neonatal outcomes of IVF\/ICSI-frozen embryo transfer","volume":"37","author":"Qiu","year":"2022","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib34","article-title":"Obesity epidemic and its impact on female fertility: current understanding and future directions","volume":"17","author":"Malhotra","year":"2025","journal-title":"Cureus"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib35","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s12958-018-0382-6","article-title":"Reproductive outcomes in women with unicornuate uterus undergoing in vitro fertilization: a nested case-control retrospective study","volume":"16","author":"Chen","year":"2018","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib36","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ejogrb.2020.12.046","article-title":"Effects of bicornuate uterus on pregnancy and obstetric outcomes of in vitro fertilization \/ intracytoplasmic sperm injection","volume":"258","author":"Kong","year":"2021","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib37","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.rbmo.2017.07.015","article-title":"Pregnancy outcomes of women with a congenital unicornuate uterus after IVF-embryo transfer","volume":"35","author":"Li","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib38","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/uog.18935","article-title":"Outcome of assisted reproduction in women with congenital uterine anomalies: a prospective observational study","volume":"51","author":"Prior","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib39","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.jmig.2022.08.004","article-title":"Reproductive outcomes and overall prognosis of women with Asherman's Syndrome undergoing IVF","volume":"29","author":"Fouks","year":"2022","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib40","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1136\/jech-2019-213364","article-title":"Association between obesity and the risk of uterine fibroids: a systematic review and meta-analysis","volume":"75","author":"Qin","year":"2021","journal-title":"J Epidemiol Community Health"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib41","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/j.fertnstert.2021.08.018","article-title":"Practice Committee of the American Society for Reproductive Medicine. Obesity and reproduction: a committee opinion","volume":"116","year":"2021","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib42","first-page":"2255","article-title":"Pregnancy outcomes following recurrent miscarriage","volume":"192","author":"Fee","year":"2023","journal-title":"Ir J Med Sci"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib43","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/aogs.15039","article-title":"Pregnancy and perinatal outcomes in women with recurrent pregnancy loss-A case-control study","volume":"104","author":"Hautamaki","year":"2025","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2024.104297","article-title":"Evaluating risk factors in recurrent pregnancy loss: a prospective cohort study and its impact on live birth outcomes","volume":"165","author":"Nielsen","year":"2024","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib45","article-title":"Predictors of miscarriage: a matched case-control study","volume":"36","author":"Poorolajal","year":"2014","journal-title":"Epidemiol Health"},{"key":"10.1016\/j.fertnstert.2026.04.016_bib46","article-title":"The role of parity in the relationship between endometriosis and pregnancy outcomes: a systematic review and meta-analysis","volume":"4","author":"Sri Ranjan","year":"2023","journal-title":"Reprod Fertil"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028226002359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028226002359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T19:38:25Z","timestamp":1793907505000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028226002359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S0015028226002359"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2026.04.016","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Obesity is associated with an increased risk of early pregnancy loss after euploid frozen embryo transfer","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2026.04.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92026 American Society for Reproductive Medicine, Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}