{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T21:23:59Z","timestamp":1794000239598,"version":"4.8.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.fertnstert.2026.07.015","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T01:06:04Z","timestamp":1784855164000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Safety and effectiveness of an in situ-forming hydrogel barrier in preventing intrauterine adhesions after adhesiogenic hysteroscopic procedures: a multicenter, randomized, controlled trial"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3925-9282","authenticated-orcid":false,"given":"Christina A.","family":"Salazar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott G.","family":"Chudnoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly H.","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather G.","family":"Huddleston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bala","family":"Bhagavath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R.","family":"Movilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Bortoletto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Grainger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles E.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Flyckt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig J.","family":"Sobolewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Livers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"James K.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vadim V.","family":"Morozov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica F.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian B.","family":"Feldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette M.","family":"Fagnant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malcolm G.","family":"Munro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2026.07.015_bib1","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.fertnstert.2008.02.096","article-title":"Asherman syndrome--one century later","volume":"89","author":"Yu","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s00404-007-0419-0","article-title":"Genital tuberculosis: an important cause of Asherman's syndrome in India","volume":"277","author":"Sharma","year":"2008","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib3","first-page":"1067","article-title":"Intrauterine adhesions: causes and treatment outcomes among Thai women","volume":"99","author":"Pongpattanawut","year":"2016","journal-title":"J Med Assoc Thai"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib4","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1111\/1471-0528.17701","article-title":"Laparoscopic and hysteroscopic findings in women with sub-fertility and tuberculosis: a case series","volume":"131","author":"Mondal","year":"2024","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib5","first-page":"588","article-title":"The epidemiology, clinical burden, and prevention of intrauterine adhesions (IUAs) related to surgically induced endometrial trauma: a systematic literature review and selective meta-analyses","volume":"31","author":"Munro","year":"2025","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib6","doi-asserted-by":"crossref","first-page":"51","DOI":"10.52054\/FVVO.14.1.005","article-title":"Reproductive performance following hysteroscopic treatment of intrauterine adhesions: single surgeon data","volume":"14","author":"Direk","year":"2022","journal-title":"Facts Views Vis Obgyn"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12958-024-01222-w","article-title":"Comparing the efficacy and pregnancy outcome of intrauterine balloon and intrauterine contraceptive device in the prevention of adhesion reformation after hysteroscopic adhesiolysis in infertile women: a prospective, randomized, controlled trial study","volume":"22","author":"Ding","year":"2024","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib8","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1093\/humrep\/dey237","article-title":"Live birth rate and obstetric complications following the hysteroscopic management of intrauterine adhesions including Asherman syndrome","volume":"33","author":"Deans","year":"2018","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib9","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.bpobgyn.2018.12.009","article-title":"Reproductive outcomes after surgical treatment of Asherman syndrome: a systematic review","volume":"59","author":"Guo","year":"2019","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib10","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jmig.2022.11.013","article-title":"Incidence and clinical implications of placenta accreta spectrum after treatment for Asherman syndrome","volume":"30","author":"Tavcar","year":"2023","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1126740","article-title":"A meta-analysis of obstetric and neonatal outcomes in patients after treatment of hysteroscopic adhesiolysis","volume":"14","author":"Wenzhi","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib12","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1016\/j.fertnstert.2025.06.027","article-title":"The threat of Asherman syndrome: a propensity score-matched study of fetal-maternal outcomes","volume":"124","author":"Hanstede","year":"2025","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib13","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1186\/s12884-022-05164-2","article-title":"The link between intrauterine adhesions and impaired reproductive performance: a systematic review of the literature","volume":"22","author":"Hooker","year":"2022","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib14","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.ajog.2021.09.015","article-title":"Postsurgical barrier strategies to avoid the recurrence of intrauterine adhesion formation after hysteroscopic adhesiolysis: a network meta-analysis of randomized controlled trials","volume":"226","author":"Vitale","year":"2022","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib15","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1186\/s12884-026-08778-y","article-title":"Comparing durations of intrauterine balloon placement for intrauterine adhesions after hysteroscopic surgery: a systematic review and meta-analysis","volume":"26","author":"Xu","year":"2026","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib16","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/0002-9378(78)90322-8","article-title":"Hysteroscopic management of intrauterine adhesions","volume":"130","author":"March","year":"1978","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib17","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/ijgo.12666","article-title":"The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions","volume":"143","author":"Munro","year":"2018","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib18","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.jmig.2022.04.004","article-title":"The effect of estrogen in the prevention of adhesion reformation after hysteroscopic adhesiolysis: a prospective randomized control trial","volume":"29","author":"Yang","year":"2022","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib19","doi-asserted-by":"crossref","DOI":"10.1002\/rmb2.12526","article-title":"Hormonal support in women with Asherman syndrome does not lead to better outcomes: a randomized trial","volume":"22","author":"Hanstede","year":"2023","journal-title":"Reprod Med Biol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib20","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1093\/humrep\/deh238","article-title":"Effectiveness of auto-crosslinked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopic surgery: a prospective, randomized, controlled study","volume":"19","author":"Guida","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib21","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/j.fertnstert.2015.08.039","article-title":"Results of centralized Asherman surgery, 2003\u20132013","volume":"104","author":"Hanstede","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib22","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.ajog.2016.05.001","article-title":"Intrauterine adhesion prevention after hysteroscopy: a systematic review and meta-analysis","volume":"215","author":"Healy","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib23","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.tjog.2019.09.002","article-title":"Meta-analysis on the use of hyaluronic acid gel to prevent recurrence of intrauterine adhesion after hysteroscopic adhesiolysis","volume":"58","author":"Fei","year":"2019","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib24","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.ejogrb.2016.05.050","article-title":"Prevention of intrauterine post-surgical adhesions in hysteroscopy. A systematic review","volume":"203","author":"Di Spiezio Sardo","year":"2016","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib25","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3389\/fsurg.2019.00050","article-title":"Early second-look hysteroscopy: prevention and treatment of intrauterine post-surgical adhesions","volume":"6","author":"Sebbag","year":"2019","journal-title":"Front Surg"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib26","first-page":"67","article-title":"Crosslinked hyaluronic acid gels for the prevention of intrauterine adhesions after a hysteroscopic myomectomy in women with submucosal myomas: a prospective, randomized, controlled trial","volume":"10","author":"Huang","year":"2020","journal-title":"Life (Basel)"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib27","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1097\/PAS.0b013e318159a2a0","article-title":"Diagnosing endometrial hyperplasia: why is it so difficult to agree?","volume":"32","author":"Allison","year":"2008","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib28","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/sj.bjc.6604102","article-title":"Endometrial carcinoma risk among women diagnosed with endometrial hyperplasia: the 34-year experience in a large health plan","volume":"98","author":"Lacey","year":"2008","journal-title":"Br J Cancer"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0302252","article-title":"Factors associated with interobserver variation amongst pathologists in the diagnosis of endometrial hyperplasia: a systematic review","volume":"19","author":"McCoy","year":"2024","journal-title":"PLoS One"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib30","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1093\/humupd\/dmt045","article-title":"Systematic review and meta-analysis of intrauterine adhesions after miscarriage: prevalence, risk factors and long-term reproductive outcome","volume":"20","author":"Hooker","year":"2014","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib31","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1007\/s00404-024-07460-y","article-title":"Intrauterine interventions options for preventing recurrence after hysteroscopic adhesiolysis: a systematic review and network meta-analysis of randomized controlled trials","volume":"309","author":"Tang","year":"2024","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib32","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1093\/humrep\/deg368","article-title":"Effectiveness of auto-cross-linked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopic adhesiolysis: a prospective, randomized, controlled study","volume":"18","author":"Acunzo","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib33","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.fertnstert.2024.07.020","article-title":"Effectiveness of degradable polymer film in the management of severe or moderate intrauterine adhesions (PREG-2): a randomized, double-blind, multicenter, stratified, superiority trial","volume":"122","author":"Fernandez","year":"2024","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib34","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s00404-019-05368-6","article-title":"Cross-linked hyaluronan gel to improve pregnancy rate of women patients with moderate to severe intrauterine adhesion treated with IVF: a randomized controlled trial","volume":"301","author":"Mao","year":"2020","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib35","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.jmig.2022.05.004","article-title":"Postsurgical intrauterine adhesions after hysteroscopic myomectomy using the myoma pseudocapsule preservation technique evaluated bv second-look hysteroscopy: a retrospective comparative study","volume":"29","author":"Ikemoto","year":"2022","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib36","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.fertnstert.2007.05.027","article-title":"Office hysteroscopic early lysis of intrauterine adhesion after transcervical resection of multiple apposing submucous myomas","volume":"89","author":"Yang","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2026.07.015_bib37","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/jog.15499","article-title":"Intrauterine adhesion after hysteroscopic myomectomy of submucous myomas","volume":"49","author":"Takasaki","year":"2023","journal-title":"J Obstet Gynaecol Res"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028226005716?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028226005716?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:25:44Z","timestamp":1793996744000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028226005716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":37,"alternative-id":["S0015028226005716"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2026.07.015","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Safety and effectiveness of an in situ-forming hydrogel barrier in preventing intrauterine adhesions after adhesiogenic hysteroscopic procedures: a multicenter, randomized, controlled trial","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2026.07.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92026 The Authors. Published by Elsevier Inc. on behalf of the American Society for Reproductive Medicine.","name":"copyright","label":"Copyright"}]}}