{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T23:06:10Z","timestamp":1778108770938,"version":"3.51.4"},"reference-count":61,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fungal Genetics and Biology"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.fgb.2012.01.010","type":"journal-article","created":{"date-parts":[[2012,2,8]],"date-time":"2012-02-08T18:47:47Z","timestamp":1328726867000},"page":"322-331","source":"Crossref","is-referenced-by-count":48,"title":["Pga13 in Candida albicans is localized in the cell wall and influences cell surface properties, morphogenesis and virulence"],"prefix":"10.1016","volume":"49","author":[{"given":"Samuel","family":"Gelis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piet W.J.","family":"de Groot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda-Dolores","family":"Moragues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Sentandreu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda-Micaela","family":"G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eulogio","family":"Valent\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fgb.2012.01.010_b0005","doi-asserted-by":"crossref","first-page":"6672","DOI":"10.1073\/pnas.83.18.6672","article-title":"Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Escherichia coli: demonstration of immunogenicity in vivo and expression in vitro","volume":"83","author":"Aldovini","year":"1986","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.fgb.2012.01.010_b0010","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1002\/1097-0061(20000915)16:12<1121::AID-YEA614>3.0.CO;2-U","article-title":"Evaluation of the CaMAL2 promoter for regulated expression of genes in Candida albicans","volume":"16","author":"Backen","year":"2000","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2012.01.010_b0015","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1128\/EC.05044-11","article-title":"Unexpected role for a serine\/threonine-rich domain in the Candida albicans Iff protein family","volume":"10","author":"Boisram\u00e9","year":"2011","journal-title":"Eukaryot. Cell."},{"key":"10.1016\/j.fgb.2012.01.010_b0020","series-title":"Methods in yeast genetics. A Cold Spring Harbor Laboratory Course Manual","author":"Burke","year":"2000"},{"key":"10.1016\/j.fgb.2012.01.010_b0025","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/nature08064","article-title":"Evolution of pathogenicity and sexual reproduction in eight Candida genomes","volume":"459","author":"Butler","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.fgb.2012.01.010_b0030","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1099\/mic.0.038000-0","article-title":"PHR1, a pH-regulated gene of Candida albicans encoding a glucan-remodelling enzyme, is required for adhesion and invasion","volume":"156","author":"Calderon","year":"2010","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2012.01.010_b0035","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0966-842X(01)02094-7","article-title":"Virulence factors of Candida albicans","volume":"9","author":"Calderone","year":"2001","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.fgb.2012.01.010_b0040","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.fbr.2007.02.007","article-title":"Determinants of virulence in the pathogenic fungi","volume":"21","author":"Casadevall","year":"2007","journal-title":"Fungal Biol. Rev."},{"key":"10.1016\/j.fgb.2012.01.010_b0045","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1128\/IAI.57.1.262-271.1989","article-title":"Identification of wall-specific antigens synthesized during germ tube formation by Candida albicans","volume":"57","author":"Casanova","year":"1989","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fgb.2012.01.010_b0050","doi-asserted-by":"crossref","first-page":"3871","DOI":"10.1002\/pmic.200800110","article-title":"A study of the Candida albicans cell wall proteome","volume":"8","author":"Castillo","year":"2008","journal-title":"Proteomics"},{"key":"10.1016\/j.fgb.2012.01.010_b0055","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.fgb.2005.12.002","article-title":"Genomic response programs of Candida albicans following protoplasting and regeneration","volume":"43","author":"Castillo","year":"2006","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.01.010_b0060","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1128\/MMBR.00032-07","article-title":"Candida albicans cell wall proteins","volume":"72","author":"Chaffin","year":"2008","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.fgb.2012.01.010_b0065","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/nrmicro1426","article-title":"Signalling and oxidant adaptation in Candida albicans and Aspergillus fumigatus","volume":"4","author":"Chauhan","year":"2006","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.fgb.2012.01.010_b0070","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/yea.1790","article-title":"The Candida albicans cell wall protein Rhd3\/Pga29 is abundant in the yeast form and contributes to virulence","volume":"27","author":"De Boer","year":"2010","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2012.01.010_b0075","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.fgb.2011.12.009","article-title":"ProFASTA: a pipeline web server for fungal protein scanning with integration of cell surface prediction software","volume":"49","author":"De Groot","year":"2012","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.01.010_b0080","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1128\/EC.3.4.955-965.2004","article-title":"Proteomic analysis of Candida albicans cell walls reveals covalently bound carbohydrate-active enzymes and adhesins","volume":"3","author":"De Groot","year":"2004","journal-title":"Eukaryot. Cell."},{"key":"10.1016\/j.fgb.2012.01.010_b0085","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/yea.1007","article-title":"Genome-wide identification of fungal GPI proteins","volume":"20","author":"De Groot","year":"2003","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2012.01.010_b0090","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1128\/EC.00284-08","article-title":"The cell wall of the human pathogen Candida glabrata: differential incorporation of novel adhesin-like wall proteins","volume":"7","author":"De Groot","year":"2008","journal-title":"Eukaryot. Cell."},{"key":"10.1016\/j.fgb.2012.01.010_b0095","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/yea.320060605","article-title":"An assay of relative cell wall porosity in Saccharomyces cerevisiae, Kluyveromyces lactis and Schizosaccharomyces pombe","volume":"6","author":"De Nobel","year":"1990","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2012.01.010_b0100","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1002\/yea.320060606","article-title":"The glucanase-soluble mannoproteins limit cell wall porosity in Saccharomyces cerevisiae","volume":"6","author":"De Nobel","year":"1990","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2012.01.010_b0105","doi-asserted-by":"crossref","first-page":"11523","DOI":"10.1074\/jbc.M600314200","article-title":"PIR-proteins of Saccharomyces cerevisiae are attached to \u03b2-1,3-glucan by a new protein\u2013carbohydrate linkage","volume":"281","author":"Ecker","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fgb.2012.01.010_b0110","first-page":"2393","article-title":"Wall mannoproteins of the yeast and mycelial cells of Candida albicans: nature of the glycosidic bonds and polydispersity of their mannan moieties","volume":"134","author":"Elorza","year":"1988","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.fgb.2012.01.010_b0115","first-page":"2209","article-title":"Dimorphism in Candida albicans: contribution of mannoproteins to the architecture of yeast and mycelial cell walls","volume":"131","author":"Elorza","year":"1985","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.fgb.2012.01.010_b0120","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1093\/genetics\/134.3.717","article-title":"Isogenic strain construction and gene mapping in Candida albicans","volume":"134","author":"Fonzi","year":"1993","journal-title":"Genetics"},{"key":"10.1016\/j.fgb.2012.01.010_b0125","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1099\/mic.0.26301-0","article-title":"Identification and study of a Candida albicans protein homologous to Saccharomyces cerevisiae Ssr1p, an internal cell-wall protein","volume":"149","author":"Garcer\u00e1","year":"2003","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2012.01.010_b0130","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1091\/mbc.E05-01-0071","article-title":"Global roles of Ssn6 in Tup1- and Nrg1-dependent gene regulation in the fungal pathogen, Candida albicans","volume":"16","author":"Garc\u00eda-S\u00e1nchez","year":"2005","journal-title":"Mol. Biol. Cell."},{"key":"10.1016\/j.fgb.2012.01.010_b0135","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1099\/mic.0.049395-0","article-title":"Hyphal induction in the human fungal pathogen Candida albicans reveals a characteristic wall protein profile","volume":"157","author":"Heilmann","year":"2011","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2012.01.010_b0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/13693780701435317","article-title":"Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family \u2013 a sticky pursuit","volume":"46","author":"Hoyer","year":"2008","journal-title":"Med. Mycol."},{"key":"10.1016\/j.fgb.2012.01.010_b0145","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1046\/j.1365-2958.2000.01729.x","article-title":"The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants","volume":"35","author":"Kapteyn","year":"2000","journal-title":"Mol. Microbiol."},{"issue":"Suppl. 1","key":"10.1016\/j.fgb.2012.01.010_b0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/744118876","article-title":"Molecular organization of the cell wall of Candida albicans","volume":"39","author":"Klis","year":"2001","journal-title":"Med. Mycol."},{"key":"10.1016\/j.fgb.2012.01.010_b0155","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1111\/j.1567-1364.2009.00541.x","article-title":"Covalently linked cell wall proteins of Candida albicans and their role in fitness and virulence","volume":"9","author":"Klis","year":"2009","journal-title":"FEMS Yeast Res."},{"key":"10.1016\/j.fgb.2012.01.010_b0160","first-page":"186","article-title":"Candida biofilms: antifungal resistance and emerging therapeutic options","volume":"5","author":"Kuhn","year":"2004","journal-title":"Curr. Opin. Investig. Drugs"},{"key":"10.1016\/j.fgb.2012.01.010_b0165","series-title":"Reference method for broth dilution antifungal susceptibility testing of yeast; approved standard","author":"Laboratory_Standards_Institute, C.a.","year":"2008"},{"key":"10.1016\/j.fgb.2012.01.010_b0170","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1567-1364.2011.00727.x","article-title":"Pga26 mediates filamentation and biofilm formation and is required for virulence in Candida albicans","volume":"11","author":"Laforet","year":"2011","journal-title":"FEMS Yeast Res."},{"key":"10.1016\/j.fgb.2012.01.010_b0175","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1128\/MMBR.00038-05","article-title":"Cell wall assembly in Saccharomyces cerevisiae","volume":"70","author":"Lesage","year":"2006","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.fgb.2012.01.010_b0180","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1128\/EC.00279-10","article-title":"Candida albicans Als3, a multifunctional adhesin and invasin","volume":"10","author":"Liu","year":"2011","journal-title":"Eukaryot. Cell."},{"key":"10.1016\/j.fgb.2012.01.010_b0185","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0092-8674(00)80358-X","article-title":"Nonfilamentous C. albicans mutants are avirulent","volume":"90","author":"Lo","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.fgb.2012.01.010_b0190","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.fgb.2009.06.005","article-title":"Trifluoromethanesulfonic acid-based proteomic analysis of cell wall and secreted proteins of the ascomycetous fungi Neurospora crassa and Candida albicans","volume":"46","author":"Maddi","year":"2009","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.01.010_b0195","doi-asserted-by":"crossref","first-page":"3341","DOI":"10.1099\/mic.0.27320-0","article-title":"The GPI-anchored protein CaEcm33p is required for cell wall integrity, morphogenesis and virulence in Candida albicans","volume":"150","author":"Martinez-Lopez","year":"2004","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2012.01.010_b0200","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1099\/mic.0.27220-0","article-title":"Role of Pir1 in the construction of the Candida albicans cell wall","volume":"150","author":"Martinez","year":"2004","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2012.01.010_b0205","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1099\/mic.0.028902-0","article-title":"The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integrity","volume":"155","author":"Moreno-Ruiz","year":"2009","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2012.01.010_b0210","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/yea.1733","article-title":"Dosage-dependent roles of the Cwt1 transcription factor for cell wall architecture, morphogenesis, drug sensitivity and virulence in Candida albicans","volume":"27","author":"Moreno","year":"2010","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2012.01.010_b0215","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/1097-0061(20000315)16:4<325::AID-YEA538>3.0.CO;2-#","article-title":"CIp10, an efficient and convenient integrating vector for Candida albicans","volume":"16","author":"Murad","year":"2000","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2012.01.010_b0220","doi-asserted-by":"crossref","first-page":"4742","DOI":"10.1093\/emboj\/20.17.4742","article-title":"NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans","volume":"20","author":"Murad","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.fgb.2012.01.010_b0225","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0076-6879(99)10008-9","article-title":"Genetic approaches to study of biofilms","volume":"310","author":"O\u2019Toole","year":"1999","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.fgb.2012.01.010_b0230","doi-asserted-by":"crossref","first-page":"6263","DOI":"10.1073\/pnas.83.17.6263","article-title":"Synthesis of an O-glycosylated cell surface protein induced in yeast by \u03b1 factor","volume":"83","author":"Orlean","year":"1986","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.fgb.2012.01.010_b0235","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1086\/596757","article-title":"Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America","volume":"48","author":"Pappas","year":"2009","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.fgb.2012.01.010_b0240","doi-asserted-by":"crossref","first-page":"40852","DOI":"10.1074\/jbc.M400216200","article-title":"The ATC1 gene encodes a cell wall-linked acid trehalase required for growth on trehalose in Candida albicans","volume":"279","author":"Pedre\u00f1o","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fgb.2012.01.010_b0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408410903241444","article-title":"Epidemiology of invasive mycoses in North America","volume":"36","author":"Pfaller","year":"2010","journal-title":"Crit. Rev. Microbiol."},{"key":"10.1016\/j.fgb.2012.01.010_b0250","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.fgb.2008.08.003","article-title":"Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity","volume":"45","author":"Plaine","year":"2008","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.01.010_b0255","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1002\/(SICI)1097-0061(199612)12:15<1535::AID-YEA59>3.0.CO;2-D","article-title":"A novel cell wall protein specific to the mycelial form of Yarrowia lipolytica","volume":"12","author":"Ram\u00f3n","year":"1996","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2012.01.010_b0260","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1128\/EC.00297-06","article-title":"Comprehensive analysis of glycosylphosphatidylinositol-anchored proteins in Candida albicans","volume":"6","author":"Richard","year":"2007","journal-title":"Eukaryot. Cell."},{"key":"10.1016\/j.fgb.2012.01.010_b0265","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1128\/AAC.47.4.1220-1227.2003","article-title":"Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates","volume":"47","author":"Rogers","year":"2003","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.fgb.2012.01.010_b0270","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1567-1364.2005.00017.x","article-title":"Molecular organization of the cell wall of Candida albicans and its relation to pathogenicity","volume":"6","author":"Ruiz-Herrera","year":"2006","journal-title":"FEMS Yeast Res."},{"key":"10.1016\/j.fgb.2012.01.010_b0305","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1128\/MCB.15.2.601","article-title":"PHR1, a pH regulated gene of Candida albicans, is required for morphogenesis","volume":"15","author":"Saporito-Irwin","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.fgb.2012.01.010_b0275","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1471-2180-9-25","article-title":"A Candida albicans early stage biofilm detachment event in rich medium","volume":"9","author":"Sellam","year":"2009","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.fgb.2012.01.010_b0280","doi-asserted-by":"crossref","first-page":"3042","DOI":"10.1128\/IAI.74.5.3042-3045.2006","article-title":"A fungicidal monoclonal antibody protects against murine invasive candidiasis","volume":"74","author":"Sevilla","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fgb.2012.01.010_b0285","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1099\/mic.0.2007\/012617-0","article-title":"Hypoxic conditions and iron restriction affect the cell wall proteome of Candida albicans grown under vagina-simulative conditions","volume":"154","author":"Sosinska","year":"2008","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2012.01.010_b0290","first-page":"1419","article-title":"Solubilization and analysis of mannoprotein molecules from the cell wall of Saccharomyces cerevisiae","volume":"130","author":"Valentin","year":"1984","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.fgb.2012.01.010_b0295","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1159\/000060351","article-title":"The cell surface of Candida albicans during morphogenesis","volume":"5","author":"Valent\u00edn","year":"2000","journal-title":"Contrib. Microbiol."},{"key":"10.1016\/j.fgb.2012.01.010_b0300","series-title":"Microarrays: Optional Technologies and Informatics","first-page":"141","article-title":"Normalization for cDNA microarray data","author":"Yang","year":"2001"}],"container-title":["Fungal Genetics and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1087184512000278?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1087184512000278?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T06:04:18Z","timestamp":1713506658000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1087184512000278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S1087184512000278"],"URL":"https:\/\/doi.org\/10.1016\/j.fgb.2012.01.010","relation":{},"ISSN":["1087-1845"],"issn-type":[{"value":"1087-1845","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}