{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T10:46:28Z","timestamp":1770633988000,"version":"3.49.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fungal Genetics and Biology"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.fgb.2012.08.010","type":"journal-article","created":{"date-parts":[[2012,10,15]],"date-time":"2012-10-15T22:32:44Z","timestamp":1350340364000},"page":"1033-1043","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Aspergillus nidulans galactofuranose biosynthesis affects antifungal drug sensitivity"],"prefix":"10.1016","volume":"49","author":[{"given":"Md Kausar","family":"Alam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amira M.","family":"El-Ganiny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharmin","family":"Afroz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.R.","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juxin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan G.W.","family":"Kaminskyj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fgb.2012.08.010_b0005","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.fgb.2011.06.001","article-title":"The UDP-galactofuranose transporter, UgtA in Aspergillus nidulans contributes to wild type hyphal morphogenesis and conidiation","volume":"48","author":"Afroz","year":"2011","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.08.010_b0010","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0161-5890(85)90158-0","article-title":"Galactofuranosyl groups are immunodominant in Aspergillus fumigatus galactomannan","volume":"22","author":"Bennett","year":"1985","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fgb.2012.08.010_b0015","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1365-2958.2009.06936.x","article-title":"The antifungal protein PAF interferes with PKC\/MPK and cAMP\/PKA signalling of Aspergillus nidulans","volume":"75","author":"Binder","year":"2010","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fgb.2012.08.010_b0020","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.jbiotec.2007.08.005","article-title":"Selection of reference genes for normalisation of specific gene quantification data of Aspergillus niger","volume":"132","author":"Bohle","year":"2007","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.fgb.2012.08.010_b0025","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1046\/j.1365-2672.2003.01870.x","article-title":"Metal ion enhancement of fungal growth, gene expression and aflatoxin synthesis in Aspergillus flavus: RT-PCR characterization","author":"Cuero","year":"2003","journal-title":"Appl. Microbiol."},{"key":"10.1016\/j.fgb.2012.08.010_b0030","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1534\/genetics.107.073148","article-title":"A novel screening method for cell wall mutants in Aspergillus niger identifies UDP-galactopyranose mutase as an important protein in fungal cell wall biosynthesis","volume":"178","author":"Damveld","year":"2008","journal-title":"Genetics"},{"key":"10.1016\/j.fgb.2012.08.010_b0035","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/S0140-6736(03)14472-8","article-title":"Echinocandin antifungal drugs","volume":"362","author":"Denning","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.fgb.2012.08.010_b0040","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.fgb.2008.09.008","article-title":"Aspergillus nidulans UDP-galactopyranose mutase (ugmA) plays key roles in colony growth, hyphal morphogensis, and conidiation","volume":"45","author":"El-Ganiny","year":"2008","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.08.010_b0045","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.fgb.2010.03.002","article-title":"Aspergillus nidulans UDP-glucose-4-epimerase UgeA has multiple roles in wall architecture, hyphal morphogenesis, and asexual development","volume":"47","author":"El-Ganiny","year":"2010","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.08.010_b0050","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/j.1469-0691.2009.02929.x","article-title":"Trends in invasive fungal infections, with emphasis on invasive aspergillosis","volume":"15","author":"Erjavec","year":"2009","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.fgb.2012.08.010_b0055","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1130-1406(09)70004-X","article-title":"Novel antifungal agents, targets or therapeutic strategies for the treatment of invasive fungal diseases: a review of the literature (2005\u20132009)","volume":"26","author":"Espinel-Ingroff","year":"2009","journal-title":"Rev. Ibero Micol."},{"key":"10.1016\/j.fgb.2012.08.010_b0060","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1093\/glycob\/cwp206","article-title":"Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus","volume":"2010","author":"Fang","year":"2010","journal-title":"Glycobiology"},{"key":"10.1016\/j.fgb.2012.08.010_b0065","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nature10947","article-title":"Emerging fungal threats to animal, plant, and ecosystem health","volume":"484","author":"Fisher","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.fgb.2012.08.010_b0070","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1128\/AAC.01154-08","article-title":"Differential effects of inhibiting chitin and 1,3-beta-D-glucan synthesis in Ras and calcineurin mutants of Aspergillus fumigatus","volume":"53","author":"Fortwendel","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.fgb.2012.08.010_b0075","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1128\/EC.05080-11","article-title":"Putative stress sensors WscA and WscB are involved in hypo-osmoticand acidic pH stress tolerance in Aspergillus nidulans","volume":"11","author":"Futagami","year":"2011","journal-title":"Eukaryotic Cell"},{"key":"10.1016\/j.fgb.2012.08.010_b0080","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.drudis.2008.11.013","article-title":"Targeting virulence: a new paradigm for antifungals","volume":"14","author":"Gauwerky","year":"2009","journal-title":"Drug Discovery Today"},{"key":"10.1016\/j.fgb.2012.08.010_b0085","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.ijmm.2011.02.003","article-title":"Studies on galactofuranose-containing microstructures of the pathogenic mold Aspergillus fumigatus","volume":"301","author":"Heesemann","year":"2011","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.fgb.2012.08.010_b0090","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1128\/EC.05270-11","article-title":"1,3 Glucans are dispensable in Aspergillus fumigatus","volume":"11","author":"Henry","year":"2011","journal-title":"Eukaryotic Cell"},{"key":"10.1016\/j.fgb.2012.08.010_b0095","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1371\/journal.ppat.0030024","article-title":"Essential gene identification and drug target prioritization in Aspergillus fumigatus","volume":"3","author":"Hu","year":"2007","journal-title":"PLoS Pathol."},{"key":"10.1016\/j.fgb.2012.08.010_b0100","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1099\/00221287-148-5-1335","article-title":"Repression of chsB expression reveals the functional importance of class IV chitin synthase gene chsD in hyphal growth and conidiation of Aspergillus nidulans","volume":"148","author":"Ichinomiya","year":"2002","journal-title":"Microbiology (Reading)"},{"key":"10.1016\/j.fgb.2012.08.010_b0105","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1099\/mic.0.2008\/019240-0","article-title":"GDP-mannose pyrophosphorylase is essential for cell wall integrity, morphogenesis and viability of Aspergillus fumigatus","volume":"154","author":"Jiang","year":"2008","journal-title":"Microbiology (Reading)"},{"key":"10.1016\/j.fgb.2012.08.010_b0110","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1006\/fgbi.2000.1238","article-title":"Septum position is marked at the tip of Aspergillus nidulans hyphae","volume":"31","author":"Kaminskyj","year":"2000","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.08.010_b0115","first-page":"25","article-title":"Fundamentals of growth, storage, genetics and microscopy of Aspergillus nidulans","volume":"48","author":"Kaminskyj","year":"2001","journal-title":"Fungal Genet Newsl."},{"key":"10.1016\/j.fgb.2012.08.010_b0120","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-60761-795-2_1","article-title":"The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions","volume":"661","author":"Keshet","year":"2010","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.fgb.2012.08.010_b0125","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1128\/AAC.01131-08","article-title":"Antifungal activity of Caspofungin in combination with Amphotericin B against Candida glabrata: comparison of disk diffusion, Etest, and time-kill methods","volume":"53","author":"Kiraz","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.fgb.2012.08.010_b0130","doi-asserted-by":"crossref","first-page":"10498","DOI":"10.1074\/jbc.M700023200","article-title":"Targeted gene deletion of Leishmania major UDP-galactopyranose mutase leads to attenuated virulence","volume":"282","author":"Kleckza","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fgb.2012.08.010_b0135","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1093\/jac\/dkg090","article-title":"Combination of caspofungin with inhibitors of the calcineurin pathway attenuates growth in vitro in Aspergillus species","volume":"51","author":"Kontoyiannis","year":"2003","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.fgb.2012.08.010_b0140","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1439-0507.2009.01691.x","article-title":"The changing face of epidemiology of invasive fungal disease in Europe","volume":"52","author":"Lass-Florl","year":"2009","journal-title":"Mycoses"},{"key":"10.1016\/j.fgb.2012.08.010_b0145","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1365-2958.2007.05872.x","article-title":"The cell wall: a carbohydrate armour for the fungal cell","volume":"66","author":"Latg\u00e9","year":"2007","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fgb.2012.08.010_b0150","doi-asserted-by":"crossref","first-page":"S104","DOI":"10.1080\/13693780802258832","article-title":"Galactofuranose containing molecules in Aspergillus fumigatus","volume":"47","author":"Latg\u00e9","year":"2009","journal-title":"Med. Mycol."},{"key":"10.1016\/j.fgb.2012.08.010_b0155","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2-\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fgb.2012.08.010_b0160","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/jac\/dkp270","article-title":"Identification of novel cell wall destabilizing antifungal compounds using a conditional Aspergillus nidulans protein kinase C mutant","volume":"64","author":"Mircus","year":"2009","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.fgb.2012.08.010_b0165","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.fgb.2009.10.010","article-title":"Study of the essentiality of the Aspergillus fumigatus triA gene, encoding RNA triphosphatase, using the heterokaryon rescue technique and the conditional gene expression driven by the alcA and niiA promoters","volume":"47","author":"Monteiro","year":"2010","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.08.010_b0170","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1038\/nprot.2006.406","article-title":"Identification and analysis of essential Aspergillus nidulans genes using the heterokaryon rescue technique","volume":"1","author":"Osmani","year":"2006","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.fgb.2012.08.010_b0175","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1128\/EC.00304-10","article-title":"Quantifying the importance of galactofuranose in Aspergillus nidulans hyphal wall surface organization by atomic force microscopy","volume":"10","author":"Paul","year":"2011","journal-title":"Eukaryotic Cell"},{"key":"10.1016\/j.fgb.2012.08.010_b0180","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s000180300021","article-title":"Galactofuranose metabolism: a potential target for antimicrobial chemotherapy","volume":"60","author":"Pederson","year":"2003","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.fgb.2012.08.010_b0185","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1002\/cbic.200900208","article-title":"Chemistry and biology of galactofuranose-containing polysaccharides","volume":"10","author":"Richards","year":"2009","journal-title":"ChemBioChem"},{"key":"10.1016\/j.fgb.2012.08.010_b0190","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S1087-1845(03)00090-2","article-title":"The Aspergillus nidulans alcA promoter drives tightly regulated conditional gene expression in Aspergillus fumigatus permitting validation of essential genes in this human pathogen","volume":"40","author":"Romero","year":"2003","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.08.010_b0195","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00294-007-0129-y","article-title":"The Aspergillus nidulans pkcA gene is involved in polarized growth, morphogenesis and maintenance of cell wall integrity","volume":"51","author":"Ronen","year":"2007","journal-title":"Curr. Genet."},{"key":"10.1016\/j.fgb.2012.08.010_b0200","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1128\/EC.00109-08","article-title":"Contribution of galactopyranose to the virulence of the opportunistic pathogen Aspergillus fumigatus","volume":"7","author":"Schmalhorst","year":"2008","journal-title":"Eukaryotic Cell"},{"key":"10.1016\/j.fgb.2012.08.010_b0205","doi-asserted-by":"crossref","first-page":"3420","DOI":"10.1099\/mic.0.029967-0","article-title":"The cell wall galactomannan antigen from Malassezia furfur and Malassezia pachydermatis contains \u03b2-1,6-linked linear galactofuranosyl residues and its detection has diagnostic potential","volume":"155","author":"Shibata","year":"2009","journal-title":"Microbiology (Reading)"},{"key":"10.1016\/j.fgb.2012.08.010_b0210","doi-asserted-by":"crossref","first-page":"10136","DOI":"10.1073\/pnas.0914418107","article-title":"Multiple GAL pathway gene clusters evolved independently and by different mechanisms in fungi","volume":"107","author":"Slot","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.fgb.2012.08.010_b0215","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1128\/iai.60.6.2237-2245.1992","article-title":"Rat monoclonal antibodies against Aspergillus galactomannan","volume":"60","author":"Stynen","year":"1992","journal-title":"Infect Immun."},{"key":"10.1016\/j.fgb.2012.08.010_b0220","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1038\/nprot.2006.405","article-title":"Fusion PCR and gene targeting in Aspergillus nidulans","volume":"1","author":"Szewczyk","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.fgb.2012.08.010_b0225","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1091\/mbc.e09-08-0750","article-title":"A novel motif in fungal class 1 histone deacetylases is essential for growth and development of Aspergillus","volume":"21","author":"Tribus","year":"2010","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.fgb.2012.08.010_b0230","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/j.1365-2958.2008.06178.x","article-title":"The role of actin, fimbrin and endocytosis in growth of hyphae in Aspergillus nidulans","volume":"68","author":"Upadhyay","year":"2008","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fgb.2012.08.010_b0235","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.fgb.2009.09.003","article-title":"Fungal echinocandin resistance","volume":"47","author":"Walker","year":"2010","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2012.08.010_b0240","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0378-1119(89)90097-8","article-title":"Characterization of an inducible expression system in Aspergillus nidulans using alcA and tubulin-coding genes","volume":"79","author":"Waring","year":"1989","journal-title":"Gene"},{"key":"10.1016\/j.fgb.2012.08.010_b0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fgb.2004.10.002","article-title":"A rapid method for promoter exchange in Aspergillus nidulans using recombinant PCR","volume":"42","author":"Zarrin","year":"2005","journal-title":"Fungal Genet. Biol."}],"container-title":["Fungal Genetics and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1087184512001727?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1087184512001727?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T17:40:26Z","timestamp":1761068426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1087184512001727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":49,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S1087184512001727"],"URL":"https:\/\/doi.org\/10.1016\/j.fgb.2012.08.010","relation":{},"ISSN":["1087-1845"],"issn-type":[{"value":"1087-1845","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aspergillus nidulans galactofuranose biosynthesis affects antifungal drug sensitivity","name":"articletitle","label":"Article Title"},{"value":"Fungal Genetics and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fgb.2012.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}