{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:22:49Z","timestamp":1761744169575},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100010803","name":"Department of Biotechnology","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010803","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Ministry of Science and Technology"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fungal Genetics and Biology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.fgb.2015.08.004","type":"journal-article","created":{"date-parts":[[2015,8,17]],"date-time":"2015-08-17T17:24:28Z","timestamp":1439832268000},"page":"45-57","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Mapping of functional domains and characterization of the transcription factor Cph1 that mediate morphogenesis in Candida albicans"],"prefix":"10.1016","volume":"83","author":[{"given":"Protiti","family":"Maiti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priyanka","family":"Ghorai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumit","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohan","family":"Kamthan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh Kumar","family":"Tyagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asis","family":"Datta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fgb.2015.08.004_b0005","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1515\/BC-2011-252","article-title":"Polyglutamine tracts as modulators of transcriptional activation from yeast to mammals","volume":"393","author":"Atanesyan","year":"2012","journal-title":"Biol. Chem."},{"key":"10.1016\/j.fgb.2015.08.004_b0010","first-page":"551","article-title":"Candida endophthalmitis: a critical diagnosis in the critically ill","volume":"1","author":"Au","year":"2007","journal-title":"Clin. Ophthalmol."},{"key":"10.1016\/j.fgb.2015.08.004_b0015","doi-asserted-by":"crossref","first-page":"5353","DOI":"10.1128\/jb.178.18.5353-5360.1996","article-title":"The Candida albicans HYR1 gene, which is activated in response to hyphal development, belongs to a gene family encoding yeast cell wall proteins","volume":"178","author":"Bailey","year":"1996","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.fgb.2015.08.004_b0020","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1038\/nrg948","article-title":"Candida albicans: a molecular revolution built on lessons from budding yeast","volume":"3","author":"Berman","year":"2002","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.fgb.2015.08.004_b0025","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1128\/MMBR.00009-06","article-title":"Environmental sensing and signal transduction pathways regulating morphopathogenic determinants of Candida albicans","volume":"71","author":"Biswas","year":"2007","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.fgb.2015.08.004_b0030","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1126\/science.1140748","article-title":"Divergence of transcription factor binding sites across related yeast species","volume":"317","author":"Borneman","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.fgb.2015.08.004_b0035","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1128\/EC.3.4.900-909.2004","article-title":"Ectopic expression of URA3 can influence the virulence phenotypes and proteome of Candida albicans but can be overcome by targeted reintegration of URA3 at RP10 locus","volume":"3","author":"Brand","year":"2004","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.fgb.2015.08.004_b0040","first-page":"167","article-title":"Signal Transduction and Morphogenesis in Candida albicans","volume":"vol. 8","author":"Brown","year":"2007"},{"key":"10.1016\/j.fgb.2015.08.004_b0045","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0966-842X(01)02094-7","article-title":"Virulence factors of Candida albicans","volume":"9","author":"Calderone","year":"2001","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0050","doi-asserted-by":"crossref","first-page":"6101","DOI":"10.1128\/IAI.71.10.6101-6103.2003","article-title":"Evaluation of the roles of four Candida albicans genes in virulence by using gene disruption strains that express URA3 from the native locus","volume":"71","author":"Cheng","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fgb.2015.08.004_b0055","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1101\/gad.2.12a.1570","article-title":"The B-cell-specific Oct-2 protein contains POU box-and homeo box-type domains","volume":"2","author":"Clerc","year":"1988","journal-title":"Genes Dev."},{"issue":"9","key":"10.1016\/j.fgb.2015.08.004_b0060","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1089\/ars.2012.5080","article-title":"Reactive oxygen species in plant pathogenesis: the role of perylenequinone photosensitizers","volume":"19","author":"Daub","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.fgb.2015.08.004_b0065","first-page":"971","article-title":"RIM10-dependent and -independent pathways govern pH responses in Candida albicans","volume":"20","author":"Davis","year":"2000","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.fgb.2015.08.004_b0070","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1002\/(SICI)1097-0061(199911)15:15<1609::AID-YEA485>3.0.CO;2-Y","article-title":"Transformation of Candida albicans by electroporation","volume":"15","author":"De Backer","year":"1999","journal-title":"Yeast"},{"issue":"3","key":"10.1016\/j.fgb.2015.08.004_b0075","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1534\/genetics.113.159368","article-title":"New Insights into the role of NADPH oxidases in sexual development and ascospore germination in Sordaria macrospora","volume":"196","author":"Dirschnabel","year":"2014","journal-title":"Genetics"},{"key":"10.1016\/j.fgb.2015.08.004_b0080","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1128\/EC.5.2.347-358.2006","article-title":"The Cek1 and Hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen Candida albicans","volume":"5","author":"Eisman","year":"2006","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.fgb.2015.08.004_b0085","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/BF00328721","article-title":"Isolation of the Candida albicans gene for orotidine-5\u2032-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations","volume":"198","author":"Gillum","year":"1984","journal-title":"Mol. Gen. Genet."},{"key":"10.1016\/j.fgb.2015.08.004_b0090","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1126\/science.1496375","article-title":"The logic of cell division in the life cycle of yeast","volume":"257","author":"Gimeno","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.fgb.2015.08.004_b0095","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S1369-5274(02)00338-7","article-title":"Fungal morphogenesis and host invasion","volume":"5","author":"Gow","year":"2002","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0100","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nrmicro2711","article-title":"Candida albicans morphogenesis and host defence: discriminating invasion from colonization","volume":"10","author":"Gow","year":"2011","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0105","doi-asserted-by":"crossref","first-page":"14637","DOI":"10.1073\/pnas.141366998","article-title":"The human salivary peptide histatin 5 exerts its antifungal activity through the formation of reactive species","volume":"98","author":"Helmerhorst","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.fgb.2015.08.004_b0110","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.micres.2008.03.001","article-title":"Transcript profiling of a MAP kinase pathway in C. albicans","volume":"163","author":"Huang","year":"2008","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.fgb.2015.08.004_b0115","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/nrmicro752","article-title":"The biology of mating in Candida albicans","volume":"1","author":"Johnson","year":"2003","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0120","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/yea.837","article-title":"Inhibitory effect of nikkomycin Z on chitin synthases in Candida albicans","volume":"19","author":"Kim","year":"2002","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2015.08.004_b0125","doi-asserted-by":"crossref","first-page":"e39405","DOI":"10.1371\/journal.pone.0039405","article-title":"Calcofluor white combination antifunfal treatments for Trichophyton rubrum and Candida albicans","volume":"7","author":"Kingsbury","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.fgb.2015.08.004_b0130","doi-asserted-by":"crossref","first-page":"8988","DOI":"10.1074\/jbc.M104484200","article-title":"DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans","volume":"276","author":"Lane","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fgb.2015.08.004_b0135","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.cmet.2013.07.005","article-title":"Loss of cytochrome c oxidase promotes RAS-dependent ROS production from the ER resident NADPH oxidase, Yno1p, in yeast","volume":"18","author":"Leadsham","year":"2013","journal-title":"Cell Metab."},{"key":"10.1016\/j.fgb.2015.08.004_b0140","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1080\/00362177585190271","article-title":"An amino acid liquid synthetic medium for the development of mycelial and yeast forms of Candida albicans","volume":"13","author":"Lee","year":"1975","journal-title":"Sabouraudia"},{"key":"10.1016\/j.fgb.2015.08.004_b0145","doi-asserted-by":"crossref","first-page":"e1003305","DOI":"10.1371\/journal.ppat.1003305","article-title":"Genetic control of conventional and pheromone-stimulated biofilm formation in Candida albicans","volume":"9","author":"Lin","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.fgb.2015.08.004_b0150","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1126\/science.7992058","article-title":"Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog","volume":"266","author":"Liu","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.fgb.2015.08.004_b0155","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/S0092-8674(00)80358-X","article-title":"Nonfilamentous C. albicans mutants are avirulent","volume":"90","author":"Lo","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.fgb.2015.08.004_b0160","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0021-9258(17)31601-0","article-title":"Identification of a putative transcription factor in Candida albicans that can complement mating defect of Saccharomyces cerevisiae ste12 mutants","volume":"269","author":"Malathi","year":"1994","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.fgb.2015.08.004_b0165","first-page":"775","article-title":"Mechanism of action of nikkomycin and the peptide transport system of Candida albicans","volume":"131","author":"McCarthy","year":"1985","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0170","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.1128\/AAC.00446-08","article-title":"CYP56 (Dit2p) in Candida albicans: characterization and investigation of its role in growth and antifungal drug susceptibility","volume":"52","author":"Melo","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.fgb.2015.08.004_b0175","doi-asserted-by":"crossref","first-page":"14392","DOI":"10.1074\/jbc.273.23.14392","article-title":"The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism","volume":"273","author":"Mio","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fgb.2015.08.004_b0180","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1128\/jb.178.8.2416-2419.1996","article-title":"Role of three chitin synthase genes in the growth of Candida albicans","volume":"178","author":"Mio","year":"1996","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.fgb.2015.08.004_b0185","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1099\/mic.0.28616-0","article-title":"The MAP kinase signal transduction network in Candida albicans","volume":"152","author":"Monge","year":"2006","journal-title":"Microbiology"},{"issue":"2","key":"10.1016\/j.fgb.2015.08.004_b0190","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1365-2958.2004.04414.x","article-title":"Differential expression of the NRG1 repressor controls species-specific regulation of chlamydospore development in Candida albicans and Candida dubliniensis","volume":"55","author":"Staib","year":"2005","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0195","doi-asserted-by":"crossref","first-page":"3629","DOI":"10.1099\/mic.0.26640-0","article-title":"Genetic control of chlamydospore formation in Candida albicans","volume":"149","author":"Nobile","year":"2003","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2015.08.004_b0200","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1111\/j.1462-5822.2008.01198.x","article-title":"Candida albicans transcription factor Rim101 mediates pathogenic interactions through cell wall functions","volume":"10","author":"Nobile","year":"2008","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0205","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1038\/ng.605","article-title":"Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity","volume":"42","author":"Noble","year":"2010","journal-title":"Nat. Genet."},{"key":"10.1016\/j.fgb.2015.08.004_b0210","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1128\/EC.4.2.298-309.2005","article-title":"Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans","volume":"4","author":"Noble","year":"2005","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.fgb.2015.08.004_b0215","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1128\/EC.00033-08","article-title":"Functional mapping of the Candida albicans Efg1 regulator","volume":"7","author":"Noffz","year":"2008","journal-title":"Eukaryot. Cell"},{"issue":"4","key":"10.1016\/j.fgb.2015.08.004_b0220","doi-asserted-by":"crossref","first-page":"e61940","DOI":"10.1371\/journal.pone.0061940","article-title":"Global transcriptome sequencing identifies chlamydospore specific markers in Candida albicans and Candida dubliniensis","volume":"8","author":"Palige","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.fgb.2015.08.004_b0225","first-page":"273","article-title":"Virulence factors and antifungal sensitivity pattern of Candida species isolated from HIV and TB patients","volume":"51","author":"Ramesh","year":"2011","journal-title":"J. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0230","doi-asserted-by":"crossref","first-page":"e53638","DOI":"10.1371\/journal.pone.0053638","article-title":"N-acetyl glucosamine kinase, Hxk1, is involved in morphogenetic transition and metabolic gene expression in Candida albicans","volume":"8","author":"Rao","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.fgb.2015.08.004_b0235","doi-asserted-by":"crossref","first-page":"13459","DOI":"10.1074\/jbc.M708506200","article-title":"Binding of the mature hiv-1 protease the structure, stability, and ligand effect of the active site D25N mutation on","volume":"283","author":"Sayer","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fgb.2015.08.004_b0240","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1128\/MMBR.00045-10","article-title":"Regulatory circuitry governing fungal development, drug resistance, and disease","volume":"75","author":"Shapiro","year":"2011","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.fgb.2015.08.004_b0245","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1101\/gad.5.5.741","article-title":"Pheromone dependent phosphorylation of the yeast STE12 protein correlates with transcriptional activation","volume":"5","author":"Song","year":"1991","journal-title":"Genes Dev."},{"key":"10.1016\/j.fgb.2015.08.004_b9000","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S1087-1845(03)00065-3","article-title":"Disruption of Botrytis cinerea class I chitin synthase gene Bcchs1 results in cell wall weakening and reduced virulence","volume":"40","author":"Soulie","year":"2003","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2015.08.004_b0250","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s10059-012-2244-y","article-title":"A MAP kinase pathway is implicated in the pseudohyphal induction by hydrogen peroxide in Candida albicans","volume":"33","author":"Srinivasa","year":"2012","journal-title":"Mol. Cells"},{"key":"10.1016\/j.fgb.2015.08.004_b0255","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/nrmicro2636","article-title":"Growth of Candida albicans hyphae","volume":"9","author":"Sudbery","year":"2011","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0260","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1099\/jmm.0.030692-0","article-title":"Transcriptional regulation of drug resistance genes in Candida albicans biofilms in response to antifungals","volume":"60","author":"Watamoto","year":"2011","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.fgb.2015.08.004_b0265","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1101\/gad.5.4.670","article-title":"Analysis of the DNA-binding and activation properties of the human transcription factor AP-2","volume":"5","author":"Williams","year":"1991","journal-title":"Genes Dev."},{"key":"10.1016\/j.fgb.2015.08.004_b0270","doi-asserted-by":"crossref","first-page":"5910","DOI":"10.1128\/MCB.11.12.5910","article-title":"Properties of the DNA-binding domain of the Saccharomyces cerevisiae STE12 protein","volume":"11","author":"Yuan","year":"1991","journal-title":"Mol. Cell. Biol."}],"container-title":["Fungal Genetics and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1087184515300165?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1087184515300165?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T14:53:15Z","timestamp":1653058395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1087184515300165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":55,"alternative-id":["S1087184515300165"],"URL":"https:\/\/doi.org\/10.1016\/j.fgb.2015.08.004","relation":{},"ISSN":["1087-1845"],"issn-type":[{"value":"1087-1845","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mapping of functional domains and characterization of the transcription factor Cph1 that mediate morphogenesis in Candida albicans","name":"articletitle","label":"Article Title"},{"value":"Fungal Genetics and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fgb.2015.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}