{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T23:09:26Z","timestamp":1778800166109,"version":"3.51.4"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100020702","name":"Instituto Potosino de Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020702","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["A1-S-9550"],"award-info":[{"award-number":["A1-S-9550"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["225311"],"award-info":[{"award-number":["225311"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fungal Genetics and Biology"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.fgb.2021.103656","type":"journal-article","created":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T11:55:46Z","timestamp":1640865346000},"page":"103656","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Candida glabrata Hst1-Rfm1-Sum1 complex evolved to control virulence-related genes"],"prefix":"10.1016","volume":"159","author":[{"given":"Norma","family":"V\u00e1zquez-Franco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guadalupe","family":"Guti\u00e9rrez-Escobedo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Ju\u00e1rez-Reyes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Orta-Zavalza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Casta\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"De Las Pe\u00f1as","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fgb.2021.103656_b0005","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/978-1-4939-7380-4_3","article-title":"How to combine ChIP with qPCR","volume":"1689","author":"Asp","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.fgb.2021.103656_b0010","unstructured":"Ausubel, F.M., 1992. Short protocols in molecular biology. In: A Compendium of Methods From \u201cCurrent Protocols in Molecular Biology,\u201d 2nd ed. John Wiley & Sons."},{"issue":"14","key":"10.1016\/j.fgb.2021.103656_b0015","doi-asserted-by":"crossref","first-page":"3329","DOI":"10.1093\/nar\/21.14.3329","article-title":"A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae","volume":"21","author":"Baudin","year":"1993","journal-title":"Nucleic Acids Res."},{"issue":"10","key":"10.1016\/j.fgb.2021.103656_b0020","doi-asserted-by":"crossref","first-page":"5976","DOI":"10.1128\/AAC.02786-14","article-title":"Pivotal Role for a Tail Subunit of the RNA Polymerase II Mediator Complex CgMed2 in Azole Tolerance and Adherence in Candida glabrata","volume":"58","author":"Borah","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.fgb.2021.103656_bib355","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/(SICI)1097-0061(19980130)14:2<115::AID-YEA204>3.0.CO;2-2","article-title":"Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications","volume":"14","author":"Brachmann","year":"1998","journal-title":"Yeast"},{"key":"10.1016\/j.fgb.2021.103656_b0025","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1099\/mic.0.000006","article-title":"The superoxide dismutases of Candida glabrata protect against oxidative damage and are required for lysine biosynthesis, DNA integrity and chronological life survival","volume":"161","author":"Briones-Martin-del-Campo","year":"2015","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2021.103656_b0030","doi-asserted-by":"crossref","unstructured":"Byrne, K.P., Wolfe, K.H., 2005. The Yeast Gene Order Browser: Combining curated homology and syntenic context reveals gene fate in polyploid species 1456\u20131461. DOI: 10.1101\/gr.3672305.","DOI":"10.1101\/gr.3672305"},{"issue":"5","key":"10.1016\/j.fgb.2021.103656_b0035","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1101\/gr.848203","article-title":"Tn7-based genome-wide random insertional mutagenesis of Candida glabrata","volume":"13","author":"Casta\u00f1o","year":"2003","journal-title":"Genome Res."},{"key":"10.1016\/j.fgb.2021.103656_bib351","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1128\/jb.170.6.2796-2801.1988","article-title":"High-efficiency transformation of bacterial cells by electroporation","volume":"170","author":"Calvin","year":"1988","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.fgb.2021.103656_b0040","first-page":"66","article-title":"Virulence of the opportunistic pathogen mushroom Candida glabrata","volume":"48","author":"Casta\u00f1o","year":"2006","journal-title":"Rev. Latinoam. Microbiol."},{"key":"10.1016\/j.fgb.2021.103656_b0045","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1111\/j.1365-2958.2004.04465.x","article-title":"Telomere length control and transcriptional regulation of subtelomeric adhesins in Candida glabrata","volume":"55","author":"Casta\u00f1o","year":"2005","journal-title":"Mol. Microbiol."},{"issue":"12","key":"10.1016\/j.fgb.2021.103656_b0050","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1128\/MCB.01413-13","article-title":"Multisite phosphorylation of the Sum1 transcriptional repressor by S-phase kinases controls exit from meiotic prophase in yeast","volume":"34","author":"Corbi","year":"2014","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.fgb.2021.103656_bib354","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1093\/genetics\/151.3.979","article-title":"Efficient homologous and illegitimate recombination in the opportunistic yeast pathogen Candida glabrata","volume":"151","author":"Cormack","year":"1999","journal-title":"Genetics"},{"issue":"5427","key":"10.1016\/j.fgb.2021.103656_b0055","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1126\/science.285.5427.578","article-title":"An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells","volume":"285","author":"Cormack","year":"1999","journal-title":"Science (80-.)"},{"issue":"5","key":"10.1016\/j.fgb.2021.103656_b0060","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1128\/EC.00011-08","article-title":"High resistance to oxidative stress in the fungal pathogen Candida glabrata is mediated by a single catalase, Cta1p, and is controlled by the transcription factors Yap1p, Skn7p, Msn2p, and Msn4p","volume":"7","author":"Cu\u00e9llar-Cruz","year":"2008","journal-title":"Eukaryot. Cell"},{"issue":"4","key":"10.1016\/j.fgb.2021.103656_b0065","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1128\/EC.00364-12","article-title":"Adhesins in human fungal pathogens: Glue with plenty of stick","volume":"12","author":"de Groot","year":"2013","journal-title":"Eukaryot. Cell"},{"issue":"11","key":"10.1016\/j.fgb.2021.103656_b0070","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1128\/EC.00284-08","article-title":"The cell wall of the human pathogen Candida glabrata: Differential incorporation of novel adhesin-like wall proteins","volume":"7","author":"de Groot","year":"2008","journal-title":"Eukaryot. Cell"},{"issue":"18","key":"10.1016\/j.fgb.2021.103656_b0075","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1101\/gad.1121003","article-title":"Virulence-related surface glycoproteins in the yeast pathogen Candida glabrata are encoded in subtelomeric clusters and subject to RAP1- and SIR-dependent transcriptional silencing","volume":"17","author":"De Las Pe\u00f1as","year":"2003","journal-title":"Genes Dev."},{"issue":"5","key":"10.1016\/j.fgb.2021.103656_b0080","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/BF00583901","article-title":"PDR3, a new yeast regulatory gene, is homologous toPDR1 and controls the multidrug resistance phenomenon","volume":"244","author":"Delaveau","year":"1994","journal-title":"Mol. Gen. Genet. MGG"},{"issue":"7","key":"10.1016\/j.fgb.2021.103656_b0085","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1567-1364.2011.00743.x","article-title":"Candida glabrata Pwp7p and Aed1p are required for adherence to human endothelial cells","volume":"11","author":"Desai","year":"2011","journal-title":"FEMS Yeast Res."},{"issue":"5723","key":"10.1016\/j.fgb.2021.103656_b0090","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1126\/science.1108640","article-title":"Nicotinic acid limitation regulates silencing of Candida Adhesins during UTI","volume":"308","author":"Domergue","year":"2005","journal-title":"Science (80-.)"},{"issue":"5","key":"10.1016\/j.fgb.2021.103656_b0095","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1093\/nar\/gkh340","article-title":"MUSCLE: multiple sequence alignment with high accuracy and high throughput","volume":"32","author":"Edgar","year":"2004","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1016\/j.fgb.2021.103656_b0100","doi-asserted-by":"crossref","first-page":"e1000268","DOI":"10.1371\/journal.ppat.1000268","article-title":"Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence","volume":"5","author":"Ferrari","year":"2009","journal-title":"PLoS Pathog."},{"issue":"6","key":"10.1016\/j.fgb.2021.103656_b0105","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1007\/s11103-005-2150-1","article-title":"Monitoring dynamic expression of nuclear genes in Chlamydomonas reinhardtii by using a synthetic luciferase reporter gene","volume":"55","author":"Fuhrmann","year":"2004","journal-title":"Plant Mol. Biol."},{"issue":"4","key":"10.1016\/j.fgb.2021.103656_b0110","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1128\/IAI.00851-12","article-title":"Transcriptional profiling of Candida glabrata during phagocytosis by neutrophils and in the infected mouse spleen","volume":"81","author":"Fukuda","year":"2013","journal-title":"Infect. Immun."},{"issue":"1","key":"10.1016\/j.fgb.2021.103656_b0115","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1186\/1471-2164-14-623","article-title":"Comparative genomics of emerging pathogens in the Candida glabrata clade","volume":"14","author":"Gabald\u00f3n","year":"2013","journal-title":"BMC Genomics"},{"key":"10.1016\/j.fgb.2021.103656_bib352","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1534\/genetics.111.138099","article-title":"A novel downstream regulatory element cooperates with the silencing machinery to repress EPA1 expression in Candida glabrata","volume":"190","author":"Gallegos-Garcia","year":"2012","journal-title":"Genetics"},{"key":"10.1016\/j.fgb.2021.103656_b0120","doi-asserted-by":"crossref","first-page":"103287","DOI":"10.1016\/j.fgb.2019.103287","article-title":"Candida glabrata peroxiredoxins, Tsa1 and Tsa2, and sulfiredoxin, Srx1, protect against oxidative damage and are necessary for virulence","volume":"135","author":"Guti\u00e9rrez-Escobedo","year":"2020","journal-title":"Fungal Genet. Biol."},{"issue":"3","key":"10.1016\/j.fgb.2021.103656_b0125","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00294-013-0390-1","article-title":"Role of glutathione in the oxidative stress response in the fungal pathogen Candida glabrata","volume":"59","author":"Guti\u00e9rrez-Escobedo","year":"2013","journal-title":"Curr. Genet."},{"issue":"48","key":"10.1016\/j.fgb.2021.103656_b0130","doi-asserted-by":"crossref","first-page":"37347","DOI":"10.1074\/jbc.M007338200","article-title":"Multiple signals from dysfunctional mitochondria activate the pleiotropic drug resistance pathway in Saccharomyces cerevisiae","volume":"275","author":"Hallstrom","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fgb.2021.103656_b0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1746-4811-3-11","article-title":"Chromatin immunoprecipitation: Optimization, quantitative analysis and data normalization","volume":"3","author":"Haring","year":"2007","journal-title":"Plant Methods"},{"issue":"4","key":"10.1016\/j.fgb.2021.103656_b0140","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S1130-1406(05)70046-2","article-title":"Evolutionary relationships between Saccharomyces cerevisiae and other fungal species as determined from genome comparisons","volume":"22","author":"Herrero","year":"2005","journal-title":"Rev. Iberoam. Micol."},{"key":"10.1016\/j.fgb.2021.103656_b0145","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0076-6879(96)66024-8","article-title":"[22] Using CLUSTAL for multiple sequence alignments","author":"Higgins","year":"1996","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.fgb.2021.103656_b0150","doi-asserted-by":"crossref","unstructured":"Huerta-Cepas, J., Capella-Guti\u00e9rrez, S., Pryszcz, L.P., Denisov, I., Kormes, D., Marcet-houben, M., Gabaldon, T., 2011. PhylomeDB v3.0\u00a0: an expanding repository of genome-wide collections of trees, alignments and phylogeny-based orthology and paralogy predictions. 39, 556\u2013560. DOI: 10.1093\/nar\/gkq1109.","DOI":"10.1093\/nar\/gkq1109"},{"issue":"4","key":"10.1016\/j.fgb.2021.103656_b0155","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00294-015-0473-2","article-title":"The EPA2 adhesin encoding gene is responsive to oxidative stress in the opportunistic fungal pathogen Candida glabrata","volume":"61","author":"Ju\u00e1rez-Cepeda","year":"2015","journal-title":"Curr. Genet."},{"issue":"6","key":"10.1016\/j.fgb.2021.103656_b0160","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/nmeth.4285","article-title":"ModelFinder: fast model selection for accurate phylogenetic estimates","volume":"14","author":"Kalyaanamoorthy","year":"2017","journal-title":"Nat. Methods"},{"issue":"6","key":"10.1016\/j.fgb.2021.103656_b0165","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/mmi.13913","article-title":"Positive autoregulation and repression of transactivation are key regulatory features of the Candida glabrata Pdr1 transcription factor","volume":"107","author":"Khakhina","year":"2018","journal-title":"Mol. Microbiol."},{"issue":"6","key":"10.1016\/j.fgb.2021.103656_b0170","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s11046-011-9446-2","article-title":"Identification and differential gene expression of Adhesin-like wall proteins in Candida glabrata Biofilms","volume":"172","author":"Kraneveld","year":"2011","journal-title":"Mycopathologia"},{"key":"10.1016\/j.fgb.2021.103656_b0175","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1093\/molbev\/msw054","article-title":"MEGA7: molecular evolutionary genetics analysis Version 7.0 for bigger datasets","volume":"33","author":"Kumar","year":"2016","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.fgb.2021.103656_bib356","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S1567-1356(03)00175-2","article-title":"Phylogenetic circumscription of Saccharomyces, Kluyveromyces and other members of the Saccharomycetaceae, and the proposal of the new genera Lachancea, Nakaseomyces, Naumovia, Vanderwaltozyma and Zygotorulaspora","volume":"4","author":"Kurtzman","year":"2003","journal-title":"FEMS Yeast Res."},{"issue":"2","key":"10.1016\/j.fgb.2021.103656_b0180","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/bmb.20999","article-title":"A laboratory practical illustrating the use of the ChIP-qPCR method in a robust model: Estrogen receptor alpha immunoprecipitation using Mcf-7 culture cells","volume":"45","author":"Lacazette","year":"2017","journal-title":"Biochem. Mol. Biol. Educ."},{"issue":"2","key":"10.1016\/j.fgb.2021.103656_b0185","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.fgb.2009.10.007","article-title":"Fungal PDR transporters: Phylogeny, topology, motifs and function","volume":"47","author":"Lamping","year":"2010","journal-title":"Fungal Genet. Biol."},{"issue":"21","key":"10.1016\/j.fgb.2021.103656_b0190","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1093\/bioinformatics\/btm404","article-title":"Clustal W and Clustal X version 2.0","volume":"23","author":"Larkin","year":"2007","journal-title":"Bioinformatics"},{"key":"10.1016\/j.fgb.2021.103656_b0195","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.fgb.2018.05.005","article-title":"Molecular characterization of the silencing complex SIR in Candida glabrata hyperadherent clinical isolates","volume":"118","author":"Leiva-Pel\u00e1ez","year":"2018","journal-title":"Fungal Genet. Biol."},{"key":"10.1016\/j.fgb.2021.103656_b0200","doi-asserted-by":"crossref","unstructured":"L\u00f3pez-Fuentes, E., Hern\u00e1ndez-Hern\u00e1ndez, G., Castanedo, L., Guti\u00e9rrez-Escobedo, G., Oktaba, K., De las Pe\u00f1as, A., Casta\u00f1o, I., 2018. Chromatin loop formation induced by a subtelomeric protosilencer represses EPA genes in Candida glabrata. Genetics 210, 113\u2013128. DOI: 10.1534\/genetics.118.301202.","DOI":"10.1534\/genetics.118.301202"},{"issue":"15","key":"10.1016\/j.fgb.2021.103656_b0205","doi-asserted-by":"crossref","first-page":"4067","DOI":"10.1128\/MCB.01461-08","article-title":"High-affinity transporters for NAD+ precursors in Candida glabrata are regulated by Hst1 and induced in response to niacin limitation","volume":"29","author":"Ma","year":"2009","journal-title":"Mol. Cell. Biol."},{"issue":"3-4","key":"10.1016\/j.fgb.2021.103656_b0210","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s11046-013-9627-2","article-title":"Sir3 Polymorphisms in Candida glabrata Clinical Isolates","volume":"175","author":"Mart\u00ednez-Jim\u00e9nez","year":"2013","journal-title":"Mycopathologia"},{"issue":"5","key":"10.1016\/j.fgb.2021.103656_b0215","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1093\/molbev\/mst024","article-title":"Ultrafast approximation for phylogenetic bootstrap","volume":"30","author":"Minh","year":"2013","journal-title":"Mol. Biol. Evol."},{"issue":"2","key":"10.1016\/j.fgb.2021.103656_b0220","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.fgb.2009.08.002","article-title":"Regulation of multidrug resistance in pathogenic fungi","volume":"47","author":"Morschh\u00e4user","year":"2010","journal-title":"Fungal Genet. Biol."},{"issue":"1","key":"10.1016\/j.fgb.2021.103656_b0225","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00294-018-0870-4","article-title":"Multiple interfaces control activity of the Candida glabrata Pdr1 transcription factor mediating azole drug resistance","volume":"65","author":"Moye-Rowley","year":"2019","journal-title":"Curr. Genet."},{"issue":"2","key":"10.1016\/j.fgb.2021.103656_b0230","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1128\/AAC.01278-12","article-title":"STB5 is a negative regulator of azole resistance in Candida glabrata","volume":"57","author":"Noble","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"issue":"6","key":"10.1016\/j.fgb.2021.103656_b0235","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1111\/mmi.12247","article-title":"Local silencing controls the oxidative stress response and the multidrug resistance in Candida glabrata","volume":"88","author":"Orta-Zavalza","year":"2013","journal-title":"Mol. Microbiol."},{"issue":"18","key":"10.1016\/j.fgb.2021.103656_b0240","doi-asserted-by":"crossref","first-page":"6417","DOI":"10.1128\/MCB.22.18.6417-6429.2002","article-title":"Regulation of the premiddle and middle phases of expression of the NDT80 gene during sporulation of Saccharomyces cerevisiae","volume":"22","author":"Pak","year":"2002","journal-title":"Mol. Cell. Biol."},{"issue":"2","key":"10.1016\/j.fgb.2021.103656_b0245","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/mmi.14109","article-title":"Negative regulation of Candida glabrata Pdr1 by the deubiquitinase subunit Bre5 occurs in a ubiquitin independent manner","volume":"110","author":"Paul","year":"2018","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fgb.2021.103656_b0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2014.00143","article-title":"Multidrug resistance in fungi: regulation of transporter-encoding gene expression","volume":"5","author":"Paul","year":"2014","journal-title":"Front. Physiol."},{"issue":"7","key":"10.1016\/j.fgb.2021.103656_b0255","doi-asserted-by":"crossref","first-page":"e101510","DOI":"10.1371\/journal.pone.0101510","article-title":"Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: Data from the Prospective Antifungal Therapy (PATH) registry 2004\u20132008","volume":"9","author":"Pfaller","year":"2014","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.fgb.2021.103656_b0260","doi-asserted-by":"crossref","DOI":"10.18388\/abp.2010_2401","article-title":"Regulation of sporulation in the yeast Saccharomyces cerevisiae","volume":"57","author":"Piekarska","year":"2010","journal-title":"Acta Biochim. Pol."},{"key":"10.1016\/j.fgb.2021.103656_b0265","first-page":"4814","article-title":"Sum1 and Ndt80 Proteins Compete for Binding to Middle Sporulation Element Sequences That Control Meiotic","volume":"23","author":"Pierce","year":"2003","journal-title":"Gene Expression"},{"key":"10.1016\/j.fgb.2021.103656_b0270","first-page":"619","article-title":"Multiple Patterns of Resistance to Fluconazole in","volume":"41","author":"Redding","year":"2003","journal-title":"Microbiology"},{"key":"10.1016\/j.fgb.2021.103656_b0275","doi-asserted-by":"crossref","unstructured":"Roetzer, A., Gratz, N., Kovarik, P., Sch\u00c3\u00bcller, C., 2010. Autophagy supports Candida glabrata survival during phagocytosis. Cell. Microbiol. 12, 199\u2013216. DOI: 10.1111\/j.1462-5822.2009.01391.x.","DOI":"10.1111\/j.1462-5822.2009.01391.x"},{"key":"10.1016\/j.fgb.2021.103656_b0280","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.febslet.2010.12.006","article-title":"Regulation of Candida glabrata oxidative stress resistance is adapted to host environment","volume":"585","author":"Roetzer","year":"2011","journal-title":"FEBS Lett."},{"issue":"2","key":"10.1016\/j.fgb.2021.103656_b0285","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s11046-009-9233-5","article-title":"Skn7p is involved in oxidative stress response and virulence of Candida glabrata","volume":"169","author":"Saijo","year":"2010","journal-title":"Mycopathologia"},{"key":"10.1016\/j.fgb.2021.103656_b0290","doi-asserted-by":"crossref","unstructured":"Sanglard, D., Ischer, F., Calabrese, D., Majcherczyk, P.A., Bille, J., 1999. The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents. Antimicrob. Agents Chemother. 43, 2753\u201365. DOI: 10.1128\/AAC.43.11.2753.","DOI":"10.1128\/AAC.43.11.2753"},{"issue":"6","key":"10.1016\/j.fgb.2021.103656_b0295","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.4049\/jimmunol.1003730","article-title":"The Facultative Intracellular Pathogen Candida glabrata Subverts Macrophage Cytokine Production and Phagolysosome Maturation","volume":"187","author":"Seider","year":"2011","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.fgb.2021.103656_b0300","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1128\/EC.00262-13","article-title":"Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages","volume":"13","author":"Seider","year":"2014","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.fgb.2021.103656_bib353","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/genetics\/122.1.19","article-title":"A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae","volume":"122","author":"Sikorski","year":"1989","journal-title":"Genetics"},{"issue":"D1","key":"10.1016\/j.fgb.2021.103656_b0305","doi-asserted-by":"crossref","first-page":"D592","DOI":"10.1093\/nar\/gkw924","article-title":"The Candida Genome Database (CGD): Incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data","volume":"45","author":"Skrzypek","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"7187","key":"10.1016\/j.fgb.2021.103656_b0310","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/nature06836","article-title":"A nuclear receptor-like pathway regulating multidrug resistance in fungi","volume":"452","author":"Thakur","year":"2008","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.fgb.2021.103656_b0315","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3390\/jof4020060","article-title":"Adhesins in Candida glabrata","volume":"4","author":"Timmermans","year":"2018","journal-title":"J. Fungi"},{"key":"10.1016\/j.fgb.2021.103656_b0320","doi-asserted-by":"crossref","unstructured":"Trifinopoulos, J., Nguyen, L., Haeseler, A. Von, Minh, B.Q., 2016. W-IQ-TREE\u00a0: a fast online phylogenetic tool for maximum likelihood analysis 44, 232\u2013235. DOI: 10.1093\/nar\/gkw256.","DOI":"10.1093\/nar\/gkw256"},{"issue":"4","key":"10.1016\/j.fgb.2021.103656_b0325","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1128\/AAC.50.4.1384-1392.2006","article-title":"Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants","volume":"50","author":"Tsai","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"issue":"5","key":"10.1016\/j.fgb.2021.103656_b0330","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1128\/IAI.00074-13","article-title":"Gain-of-function mutations in PDR1, a regulator of antifungal drug resistance in candida glabrata, control adherence to host cells","volume":"81","author":"Vale-Silva","year":"2013","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fgb.2021.103656_b0335","doi-asserted-by":"crossref","unstructured":"Vale-Silva, L.A., Moeckli, B., Torelli, R., Posteraro, B., Sanguinetti, M., Sanglard, D., 2016. Upregulation of the Adhesin Gene EPA1 Mediated by PDR1 in Candida glabrata Leads to Enhanced Host Colonization. mSphere 1, 1\u201316. DOI: 10.1128\/mSphere.00065-15.","DOI":"10.1128\/mSphere.00065-15"},{"issue":"3","key":"10.1016\/j.fgb.2021.103656_b0340","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1111\/j.1365-2958.2006.05235.x","article-title":"Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies","volume":"61","author":"Vermitsky","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fgb.2021.103656_b0345","doi-asserted-by":"crossref","unstructured":"Whaley, S.G., Caudle, K.E., Simonicova, L., Zhang, Q., Moye-Rowley, W.S., Rogers, P.D., 2018. Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata. mSphere 3, 1\u201311. DOI: 10.1128\/msphere.00466-17.","DOI":"10.1128\/mSphere.00466-17"},{"key":"10.1016\/j.fgb.2021.103656_b0350","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s11908-016-0554-5","article-title":"Azole resistance in Candida glabrata","volume":"18","author":"Whaley","year":"2016","journal-title":"Curr. Infect. Dis. Rep."}],"container-title":["Fungal Genetics and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1087184521001407?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1087184521001407?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T22:35:20Z","timestamp":1778798120000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1087184521001407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":76,"alternative-id":["S1087184521001407"],"URL":"https:\/\/doi.org\/10.1016\/j.fgb.2021.103656","relation":{},"ISSN":["1087-1845"],"issn-type":[{"value":"1087-1845","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Candida glabrata Hst1-Rfm1-Sum1 complex evolved to control virulence-related genes","name":"articletitle","label":"Article Title"},{"value":"Fungal Genetics and Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fgb.2021.103656","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103656"}}