{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:15:13Z","timestamp":1788581713788,"version":"build-2803163510"},"reference-count":14,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fitoterapia"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.fitote.2012.10.012","type":"journal-article","created":{"date-parts":[[2012,10,24]],"date-time":"2012-10-24T19:31:32Z","timestamp":1351107092000},"page":"20-24","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"special_numbering":"C","title":["(\u2212)-Carvone: Antispasmodic effect and mode of action"],"prefix":"10.1016","volume":"85","author":[{"given":"F\u00e1bia Val\u00e9ria M.","family":"Souza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelly Barbosa","family":"da Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dami\u00e3o P.","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosilene Moretti","family":"Mar\u00e7al","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fitote.2012.10.012_bb0005","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/ffj.1288","article-title":"Essential oils and fragrance compounds: bioactivity and mechanisms of action","volume":"19","author":"Lahlou","year":"2004","journal-title":"Flavour Fragrance J"},{"key":"10.1016\/j.fitote.2012.10.012_bb0010","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1002\/ffj.1600","article-title":"R-(+)- and S-(\u2212)-carvone: influence of chirality on locomotion activity in mice","volume":"20","author":"Buchbauer","year":"2005","journal-title":"Flavour Fragrance J."},{"key":"10.1016\/j.fitote.2012.10.012_bb0015","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/chir.20379","article-title":"Influence of the chirality of (R)-(\u2212)- and (S)-(+)-carvone in the central nervous system: a comparative study","volume":"19","author":"de Sousa","year":"2007","journal-title":"Chirality"},{"key":"10.1016\/j.fitote.2012.10.012_bb0020","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/chemse\/26.3.281","article-title":"Effects of chiral fragrances on human autonomic nervous system parameters and self-evaluation","volume":"26","author":"Heuberger","year":"2001","journal-title":"Chem Senses"},{"key":"10.1016\/j.fitote.2012.10.012_bb0025","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1515\/znc-2008-11-1205","article-title":"Structure and spasmolytic activity relationships of monoterpene analogues found in many aromatic plants","volume":"63","author":"de Sousa","year":"2008","journal-title":"Z Naturforsch"},{"key":"10.1016\/j.fitote.2012.10.012_bb0030","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1111\/j.1476-5381.1991.tb12233.x","article-title":"Comparison of the effects of several potassium-channel openers on rat bladder and rat portal vein in vitro","volume":"102","author":"Edwards","year":"1991","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.fitote.2012.10.012_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-8741(02)00049-1","article-title":"Relaxant effects of the essential oil of Ocimum gratissimum on isolated ileum of the guinea pig","volume":"81","author":"Madeira","year":"2002","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.fitote.2012.10.012_bb0040","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0031-6997(24)01321-8","article-title":"Calcium movements, distribution, and functions in smooth muscle","volume":"49","author":"Karaki","year":"1997","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.fitote.2012.10.012_bb0045","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1474-8673.1989.tb00069.x","article-title":"Effects of Ca2+ antagonists and K+-channel activators on K+-induced contractions in the rat aorta","volume":"9","author":"Lawson","year":"1989","journal-title":"J Auton Pharmacol"},{"key":"10.1016\/j.fitote.2012.10.012_bb0050","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1476-5381.1957.tb01373.x","article-title":"The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum","volume":"12","author":"Paton","year":"1957","journal-title":"Br J Pharmacol Chemother"},{"key":"10.1016\/j.fitote.2012.10.012_bb0085","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jep.2008.12.019","article-title":"Evidence of the mechanism of action of Erythrina velutina Willd (Fabaceae) leaves aqueous extract","volume":"122","author":"Carvalho","year":"2009","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.fitote.2012.10.012_bb0090","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1248\/bpb.31.1017","article-title":"Antinociceptive activity of (\u2212)-carvone: evidence of association with decreased peripheral nerve excitability","volume":"31","author":"Gon\u00e7alves","year":"2008","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.fitote.2012.10.012_bb0070","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1159\/000138932","article-title":"Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats","volume":"44","author":"Gurdal","year":"1992","journal-title":"Pharmacology"},{"key":"10.1016\/j.fitote.2012.10.012_bb0075","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0014-2999(92)90833-P","article-title":"Antinociceptive effects of Ca2+ channel blockers","volume":"217","author":"Miranda","year":"1992","journal-title":"Eur J Pharmacol"}],"container-title":["Fitoterapia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0367326X12002882?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0367326X12002882?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,19]],"date-time":"2025-04-19T16:18:09Z","timestamp":1745079489000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0367326X12002882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":14,"alternative-id":["S0367326X12002882"],"URL":"https:\/\/doi.org\/10.1016\/j.fitote.2012.10.012","relation":{},"ISSN":["0367-326X"],"issn-type":[{"value":"0367-326X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"(\u2212)-Carvone: Antispasmodic effect and mode of action","name":"articletitle","label":"Article Title"},{"value":"Fitoterapia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fitote.2012.10.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}