{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T20:44:29Z","timestamp":1773953069453,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31760018"],"award-info":[{"award-number":["31760018"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31560016"],"award-info":[{"award-number":["31560016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["2014FA019"],"award-info":[{"award-number":["2014FA019"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007471","name":"Applied Basic Research Foundation of Yunnan Province","doi-asserted-by":"publisher","award":["2018FA006"],"award-info":[{"award-number":["2018FA006"]}],"id":[{"id":"10.13039\/100007471","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fitoterapia"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.fitote.2018.07.019","type":"journal-article","created":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T12:32:08Z","timestamp":1533126728000},"page":"17-25","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["New secondary metabolites from an engineering mutant of endophytic Streptomyces sp. CS"],"prefix":"10.1016","volume":"130","author":[{"given":"Yin-He","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8759-7393","authenticated-orcid":false,"given":"Da-Song","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo-Hong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Wei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke-Qin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4612-1257","authenticated-orcid":false,"given":"Pei-Ji","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fitote.2018.07.019_bb0005","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1039\/b208815k","volume":"20","author":"Firn","year":"2003","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.fitote.2018.07.019_bb0010","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.cell.2014.06.034","volume":"158","author":"Cimermancic","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.fitote.2018.07.019_bb0015","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.copbio.2017.02.008","volume":"48","author":"Ren","year":"2017","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.fitote.2018.07.019_bb0020","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/nrmicro3496","volume":"13","author":"Rutledge","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.fitote.2018.07.019_bb0025","doi-asserted-by":"crossref","first-page":"415","DOI":"10.7164\/antibiotics.56.415","volume":"56","author":"Lu","year":"2003","journal-title":"J. Antibiot."},{"key":"10.1016\/j.fitote.2018.07.019_bb0030","doi-asserted-by":"crossref","first-page":"597","DOI":"10.7164\/antibiotics.57.597","volume":"57","author":"Lu","year":"2005","journal-title":"J. Antibiot."},{"key":"10.1016\/j.fitote.2018.07.019_bb0035","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1002\/hlca.200890075","volume":"91","author":"Li","year":"2008","journal-title":"Helv. Chim. Acta."},{"key":"10.1016\/j.fitote.2018.07.019_bb0040","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1038\/ja.2010.95","volume":"63","author":"Li","year":"2010","journal-title":"J. Antibiot."},{"key":"10.1016\/j.fitote.2018.07.019_bb0045","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/ja.2007.84","volume":"60","author":"Lu","year":"2007","journal-title":"J. Antibiot."},{"key":"10.1016\/j.fitote.2018.07.019_bb0050","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1021\/np300109s","volume":"75","author":"Yang","year":"2012","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.fitote.2018.07.019_bb0055","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S1572-5995(00)80127-1","volume":"23","author":"Funayama","year":"2000","journal-title":"Stud. Nat. Prod. Chem."},{"key":"10.1016\/j.fitote.2018.07.019_bb0060","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1039\/c1mb05036b","volume":"7","author":"Wu","year":"2011","journal-title":"Mol. BioSyst."},{"key":"10.1016\/j.fitote.2018.07.019_bb0065","doi-asserted-by":"crossref","first-page":"7968","DOI":"10.1073\/pnas.092697199","volume":"99","author":"Yu","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.fitote.2018.07.019_bb0070","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/ja.2010.139","volume":"64","author":"Floss","year":"2011","journal-title":"J. Antibiot."},{"key":"10.1016\/j.fitote.2018.07.019_bb0075","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1016\/j.chembiol.2011.11.007","volume":"18","author":"Li","year":"2011","journal-title":"Chem. Biol."},{"key":"10.1016\/j.fitote.2018.07.019_bb0080","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.chembiol.2008.06.007","volume":"15","author":"Zhao","year":"2008","journal-title":"Chem. Biol."},{"key":"10.1016\/j.fitote.2018.07.019_bb0085","doi-asserted-by":"crossref","first-page":"3813","DOI":"10.1021\/jm00019a011","volume":"38","author":"Schnur","year":"1995","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.fitote.2018.07.019_bb0090","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1002\/anie.201106249","volume":"51","author":"Eichner","year":"2012","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.fitote.2018.07.019_bb0095","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0378-1119(92)90603-M","volume":"111","author":"MacNeil","year":"1992","journal-title":"Gene"},{"key":"10.1016\/j.fitote.2018.07.019_bb0100","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0378-1119(92)90627-2","volume":"116","author":"Bierman","year":"1992","journal-title":"Gene"},{"key":"10.1016\/j.fitote.2018.07.019_bb0105","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.fitote.2018.05.026","volume":"128","author":"Duan","year":"2018","journal-title":"Fitoterapia"},{"key":"10.1016\/j.fitote.2018.07.019_bb0110","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1002\/hlca.19860690610","volume":"69","author":"Meyer","year":"1986","journal-title":"Helv. Chim. Acta."},{"key":"10.1016\/j.fitote.2018.07.019_bb0115","doi-asserted-by":"crossref","first-page":"874","DOI":"10.7164\/antibiotics.32.874","volume":"32","author":"Westley","year":"1979","journal-title":"J. Antibiot."},{"key":"10.1016\/j.fitote.2018.07.019_bb0120","author":"Satoshi","year":"1989","journal-title":"Jpn. Kokai Tokkyo Koho"},{"key":"10.1016\/j.fitote.2018.07.019_bb0125","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1007\/BF01941296","volume":"42","author":"Tanida","year":"1986","journal-title":"Experientia"},{"key":"10.1016\/j.fitote.2018.07.019_bb0130","doi-asserted-by":"crossref","first-page":"948","DOI":"10.7164\/antibiotics.38.948","volume":"38","author":"Mukhopadhyay","year":"1985","journal-title":"J. Antibiot."},{"key":"10.1016\/j.fitote.2018.07.019_bb0135","doi-asserted-by":"crossref","first-page":"694","DOI":"10.7164\/antibiotics.53.694","volume":"53","author":"Nonaka","year":"2000","journal-title":"J. Antibiot."},{"key":"10.1016\/j.fitote.2018.07.019_bb0140","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1021\/jo801944d","volume":"74","author":"Kwon","year":"2009","journal-title":"J. Organomet. Chem."},{"key":"10.1016\/j.fitote.2018.07.019_bb0145","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.jbiotec.2005.12.001","volume":"124","author":"Floss","year":"2006","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.fitote.2018.07.019_bb0150","first-page":"823","volume":"9","author":"Sun","year":"2015","journal-title":"Drug Des. Dev. Ther."}],"container-title":["Fitoterapia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0367326X18309973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0367326X18309973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T07:38:51Z","timestamp":1539589131000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0367326X18309973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":30,"alternative-id":["S0367326X18309973"],"URL":"https:\/\/doi.org\/10.1016\/j.fitote.2018.07.019","relation":{},"ISSN":["0367-326X"],"issn-type":[{"value":"0367-326X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"New secondary metabolites from an engineering mutant of endophytic Streptomyces sp. CS","name":"articletitle","label":"Article Title"},{"value":"Fitoterapia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fitote.2018.07.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}