{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:46:52Z","timestamp":1790668012168,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["fsijournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Forensic Science International"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.forsciint.2013.10.025","type":"journal-article","created":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T18:05:44Z","timestamp":1383242744000},"page":"29-38","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"special_numbering":"C","title":["Characterization of heroin samples by 1H NMR and 2D DOSY 1H NMR"],"prefix":"10.1016","volume":"234","author":[{"given":"St\u00e9phane","family":"Balayssac","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Retailleau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevi\u00e8ve","family":"Bertrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Pierre","family":"Escot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Martino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Malet-Martino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Gilard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.forsciint.2013.10.025_bib0005","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/BF02258915","article-title":"Profiling of illicit heroin samples by high-resolution capillary gas-chromatography for forensic application","volume":"16","author":"Neumann","year":"1982","journal-title":"Chromatographia"},{"key":"10.1016\/j.forsciint.2013.10.025_bib0010","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.scijus.2011.07.005","article-title":"Gas chromatographic method validation for the analysis of major components in illicit heroin seized in Malaysia","volume":"52","author":"Chan","year":"2012","journal-title":"Sci. Justice"},{"key":"10.1016\/j.forsciint.2013.10.025_bib0015","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1021\/ac00297a005","article-title":"Determination of neutral manufacturing impurities in heroin by capillary gas-chromatography with electron-capture detection after reduction with lithium aluminum-hydride and derivatization with heptafluorobutyric anhydride","volume":"58","author":"Moore","year":"1986","journal-title":"Anal. Chem."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0020","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1556-4029.2006.00057.x","article-title":"Neutral heroin impurities from tetrahydrobenzylisoquinoline alkaloids","volume":"51","author":"Toske","year":"2006","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0025","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1556-4029.2009.01220.x","article-title":"Signature profiling and classification of illicit heroin by GC\u2013MS analysis of acidic and neutral manufacturing impurities","volume":"55","author":"Morello","year":"2010","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0030","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.chroma.2008.05.028","article-title":"Application of two-dimensional gas chromatography combined with pixel-based chemometric processing for the chemical profiling of illicit drug samples","volume":"1200","author":"Groger","year":"2008","journal-title":"J. Chromatogr. A."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0035","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.chroma.2004.01.062","article-title":"Use of dynamically coated capillaries for the determination of heroin basic impurities adulterants with capillary electrophoresis","volume":"1034","author":"Lurie","year":"2004","journal-title":"J. Chromatogr. A."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0040","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0021-9673(01)00732-4","article-title":"Profiling of impurities in heroin by capillary electrochromatography and laser-induced fluorescence detection","volume":"924","author":"Lurie","year":"2001","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.forsciint.2013.10.025_bib0045","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1520\/JFS12164J","article-title":"High-performance liquid-chromatographic analysis of heroin by reverse phase ion-pair chromatography","volume":"27","author":"Lurie","year":"1982","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0050","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.chroma.2008.03.011","article-title":"Applicability of ultra-performance liquid chromatography\u2013tandem mass spectrometry for heroin profiling","volume":"1188","author":"Lurie","year":"2008","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.forsciint.2013.10.025_bib0055","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1007\/s00216-010-4282-7","article-title":"Innovative methodology to transfer conventional GC\u2013MS heroin profiling to UHPLC-MS\/MS","volume":"399","author":"Debrus","year":"2011","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0060","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1520\/JFS15244J","article-title":"Classification of narcotics in solid mixtures using Principal Component Analysis and Raman spectroscopy","volume":"47","author":"Ryder","year":"2002","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0065","doi-asserted-by":"crossref","first-page":"7257","DOI":"10.1021\/ac800781c","article-title":"Nondestructive direct determination of heroin in seized illicit street drugs by diffuse reflectance near-infrared spectroscopy","volume":"80","author":"Moros","year":"2008","journal-title":"Anal. Chem."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0070","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1520\/JFS14728J","article-title":"Geographic origin determination of heroin and cocaine using site-specific isotopic ratio deuterium NMR","volume":"45","author":"Hays","year":"2000","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0075","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1520\/JFS14818J","article-title":"Identification of heroin in street doses using 1D-TOCSY nuclear magnetic resonance","volume":"45","author":"Suryaprakash","year":"2000","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0080","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1520\/JFS2005124","article-title":"Proton nuclear magnetic resonance spectroscopy (NMR) methods for determining the purity of reference drug standards and illicit forensic drug seizures","volume":"50","author":"Hays","year":"2005","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0085","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jmr.2010.11.012","article-title":"J-modulation effects in DOSY experiments and their suppression: The oneshot45 experiment","volume":"208","author":"Botana","year":"2011","journal-title":"J. Magn. Reson."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0090","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1021\/ac801982h","article-title":"Analytic properties of statistical total correlation spectroscopy based information recovery in H-1 NMR metabolic data sets","volume":"81","author":"Alves","year":"2009","journal-title":"Anal. Chem."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0095","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.chemolab.2013.04.015","article-title":"A toolbox to explore NMR metabolomics data sets using the R environment","volume":"126","author":"Balayssac","year":"2013","journal-title":"Chemom. Intell. Lab. Syst."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0100","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1007\/s00216-010-4321-4","article-title":"pH optimization for a reliable quantification of brain tumor cell and tissue extracts with 1H NMR: focus on choline-containing compounds and taurine","volume":"399","author":"Robert","year":"2011","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0105","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1021\/ac048630x","article-title":"Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets","volume":"77","author":"Cloarec","year":"2005","journal-title":"Anal. Chem."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0110","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.pnmrs.2011.04.003","article-title":"Analysis of complex mixtures using high-resolution nuclear magnetic resonance spectroscopy and chemometrics","volume":"59","author":"McKenzie","year":"2011","journal-title":"Prog. Nucl. Magn. Reson. Spectrosc."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0115","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.cbpa.2010.10.010","article-title":"NMR-spectroscopic analysis of mixtures: from structure to function","volume":"15","author":"Forseth","year":"2011","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0120","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.pnmrs.2010.05.001","article-title":"Quantitative NMR spectroscopy in pharmaceutical applications","volume":"57","author":"Holzgrabe","year":"2010","journal-title":"Prog. Nucl. Magn. Reson. Spectrosc."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0125","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.aca.2003.11.006","article-title":"Exploratory applications of diffusion ordered spectroscopy to liquid foods: an aid towards spectral assignment","volume":"506","author":"Gil","year":"2004","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.forsciint.2013.10.025_bib0130","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jpba.2007.12.033","article-title":"Analysis of illegally manufactured formulations of tadalafil (Cialis) by 1H NMR, 2D DOSY 1H NMR and Raman spectroscopy","volume":"47","author":"Trefi","year":"2008","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0135","doi-asserted-by":"crossref","first-page":"S163","DOI":"10.1002\/mrc.2490","article-title":"The usefulness of 2D DOSY and 3D DOSY-COSY 1H NMR for mixture analysis: application to genuine and fake formulations of sildenafil (Viagra)","volume":"47","author":"Trefi","year":"2009","journal-title":"Magn. Reson. Chem."},{"key":"10.1016\/j.forsciint.2013.10.025_bib0140","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.jpba.2008.10.034","article-title":"2D and 3D DOSY 1H NMR, a useful tool for analysis of complex mixtures: application to herbal drugs or dietary supplements for erectile dysfunction","volume":"50","author":"Balayssac","year":"2009","journal-title":"J. Pharm. Biomed. Anal."}],"container-title":["Forensic Science International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0379073813004702?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0379073813004702?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T00:26:17Z","timestamp":1539217577000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0379073813004702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":28,"alternative-id":["S0379073813004702"],"URL":"https:\/\/doi.org\/10.1016\/j.forsciint.2013.10.025","relation":{},"ISSN":["0379-0738"],"issn-type":[{"value":"0379-0738","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of heroin samples by 1H NMR and 2D DOSY 1H NMR","name":"articletitle","label":"Article Title"},{"value":"Forensic Science International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.forsciint.2013.10.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}