{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:36:23Z","timestamp":1762252583794,"version":"3.40.5"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Forensic Science International"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.forsciint.2017.07.025","type":"journal-article","created":{"date-parts":[[2017,7,30]],"date-time":"2017-07-30T18:00:38Z","timestamp":1501437638000},"page":"e14-e18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Advantages of analyzing postmortem brain samples in routine forensic drug screening\u2014Case series of three non-natural deaths tested positive for lysergic acid diethylamide (LSD)"],"prefix":"10.1016","volume":"278","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3203-7305","authenticated-orcid":false,"given":"Marie","family":"Mardal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9555-5134","authenticated-orcid":false,"given":"Sys Stybe","family":"Johansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ragnar","family":"Thomsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian","family":"Linnet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"year":"1980","series-title":"LSD\u2014My Problem Child","author":"Hoffman","key":"10.1016\/j.forsciint.2017.07.025_bib0005"},{"issue":"1\u20132","key":"10.1016\/j.forsciint.2017.07.025_bib0010","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0376-8716(98)00076-3","article-title":"Indoleamine and the phenethylamine hallucinogens: mechanisms of psychotomimetic action","volume":"51","author":"Marek","year":"1998","journal-title":"Drug Alcohol Depend."},{"issue":"Suppl. 2","key":"10.1016\/j.forsciint.2017.07.025_bib0015","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1055\/s-2007-979353","article-title":"Advances and pathophysiological models of hallucinogenic drug actions in humans: a preamble to schizophrenia research","volume":"31","author":"Vollenweider","year":"1998","journal-title":"Pharmacopsychiatry"},{"issue":"3","key":"10.1016\/j.forsciint.2017.07.025_bib0020","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1177\/2045125316638008","article-title":"Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years","volume":"6","author":"Dos Santos","year":"2016","journal-title":"Ther. Adv. Psychopharmacol."},{"issue":"3","key":"10.1016\/j.forsciint.2017.07.025_bib0025","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1177\/2045125316640440","article-title":"Lysergic acid diethylamide: a drug of \u2018use\u2019?","volume":"6","author":"Das","year":"2016","journal-title":"Ther. Adv. Psychopharmacol."},{"issue":"11","key":"10.1016\/j.forsciint.2017.07.025_bib0030","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1038\/npp.2016.82","article-title":"LSD acutely impairs fear recognition and enhances emotional empathy and sociality","volume":"41","author":"Dolder","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.forsciint.2017.07.025_bib0035","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0379-0738(85)90067-2","article-title":"A fatal poisoning with LSD","volume":"28","author":"Fysh","year":"1985","journal-title":"Forensic Sci. Int."},{"issue":"4","key":"10.1016\/j.forsciint.2017.07.025_bib0040","first-page":"172","article-title":"LSD toxicity: a suspected cause of death","volume":"75","author":"Griggs","year":"1977","journal-title":"J. Ky. Med. Assoc."},{"issue":"1","key":"10.1016\/j.forsciint.2017.07.025_bib0045","doi-asserted-by":"crossref","DOI":"10.1093\/ijnp\/pyv072","article-title":"Pharmacokinetics and concentration-effect relationship of oral LSD in humans","volume":"19","author":"Dolder","year":"2016","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.forsciint.2017.07.025_bib0050","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jpba.2015.07.001","article-title":"Simultaneous determination of LSD and 2-oxo-3-hydroxy LSD in hair and urine by LC\u2013MS\/MS and its application to forensic cases","volume":"115","author":"Jang","year":"2015","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"6","key":"10.1016\/j.forsciint.2017.07.025_bib0055","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1007\/s00216-014-8388-1","article-title":"Development and validation of a rapid turboflow LC\u2013MS\/MS method for the quantification of LSD and 2-oxo-3-hydroxy LSD in serum and urine samples of emergency toxicological cases","volume":"407","author":"Dolder","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"issue":"1","key":"10.1016\/j.forsciint.2017.07.025_bib0060","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jchromb.2004.12.040","article-title":"Liquid chromatography-tandem mass spectrometry determination of LSD, ISO-LSD, and the main metabolite 2-oxo-3-hydroxy-LSD in forensic samples and application in a forensic case","volume":"825","author":"Johansen","year":"2005","journal-title":"J. Chromatogr. B Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.forsciint.2017.07.025_bib0065","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/dta.2042","volume":"9","author":"Steuer","year":"2017","journal-title":"Drug Test. Anal."},{"issue":"1\u20133","key":"10.1016\/j.forsciint.2017.07.025_bib0070","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.forsciint.2011.10.021","article-title":"LSD in pubic hair in a fatality","volume":"218","author":"Gaulier","year":"2012","journal-title":"Forensic Sci. Int."},{"issue":"7","key":"10.1016\/j.forsciint.2017.07.025_bib0075","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/jat\/bkv072","article-title":"Postmortem quetiapine reference concentrations in brain and blood","volume":"39","author":"Skov","year":"2015","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.forsciint.2017.07.025_bib0080","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.forsciint.2016.09.002","article-title":"Nitrobenzodiazepines postmortem brain and blood reference concentrations","volume":"268","author":"Skov","year":"2016","journal-title":"Forensic Sci. Int."},{"issue":"7","key":"10.1016\/j.forsciint.2017.07.025_bib0085","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/jat\/bkw059","article-title":"Postmortem brain and blood reference concentrations of alprazolam, bromazepam, chlordiazepoxide, diazepam, and their metabolites and a review of the literature","volume":"40","author":"Skov","year":"2016","journal-title":"J. Anal. Toxicol."},{"issue":"2","key":"10.1016\/j.forsciint.2017.07.025_bib0090","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S1344-6223(99)80021-2","article-title":"Ethanol distribution in the brain of a victim autopsied after acute subdural hemorrhage","volume":"1","author":"Takahashi","year":"1999","journal-title":"Leg. Med. (Tokyo)"},{"issue":"13","key":"10.1016\/j.forsciint.2017.07.025_bib0095","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1002\/jssc.201200921","article-title":"Screening for illicit and medicinal drugs in whole blood using fully automated SPE and ultra-high-performance liquid chromatography with TOF-MS with data-independent acquisition","volume":"36","author":"Pedersen","year":"2013","journal-title":"J. Sep. Sci."},{"issue":"8","key":"10.1016\/j.forsciint.2017.07.025_bib0100","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1007\/s00216-012-6670-7","article-title":"Quantification of 31 illicit and medicinal drugs and metabolites in whole blood by fully automated solid-phase extraction and ultra-performance liquid chromatography\u2013tandem mass spectrometry","volume":"405","author":"Bjork","year":"2013","journal-title":"Anal. Bioanal. Chem."},{"issue":"2","key":"10.1016\/j.forsciint.2017.07.025_bib0105","first-page":"7","article-title":"Screening of Danish traffic cases for synthetic cannabinoids in whole blood by LC\u2013MS\/MS","volume":"19","author":"Holm NBP","year":"2013","journal-title":"Scand. J. Forensic Sci."},{"key":"10.1016\/j.forsciint.2017.07.025_bib0110","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.forsciint.2016.12.038","article-title":"Postmortem concentrations of gamma-hydroxybutyrate (GHB) in peripheral blood and brain tissue\u2014differentiating between postmortem formation and antemortem intake","volume":"272","author":"Thomsen","year":"2017","journal-title":"Forensic Sci. Int."},{"issue":"11","key":"10.1016\/j.forsciint.2017.07.025_bib0115","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1097\/00007611-199711000-00007","article-title":"Radionuclide angiography as a confirmatory test for brain death: a review of 229 studies in 219 patients","volume":"90","author":"Flowers","year":"1997","journal-title":"South Med. J."},{"issue":"1\u20132","key":"10.1016\/j.forsciint.2017.07.025_bib0120","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0379-0738(97)00155-2","article-title":"Distribution of drugs in various tissues in a brain dead man","volume":"90","author":"Jitsufuchi","year":"1997","journal-title":"Forensic Sci. Int."},{"issue":"Suppl. 1","key":"10.1016\/j.forsciint.2017.07.025_bib0125","doi-asserted-by":"crossref","first-page":"S118","DOI":"10.1016\/S1344-6223(02)00080-9","article-title":"Distributions of ethanol and intubation-related lidocaine in the brain of a trauma patient who was brain dead for about 5 days","volume":"5","author":"Moriya","year":"2003","journal-title":"Leg. Med. (Tokyo)"},{"issue":"2","key":"10.1016\/j.forsciint.2017.07.025_bib0130","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/jat\/26.2.113","article-title":"Distribution study of 3,4-methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine in a fatal overdose","volume":"26","author":"De Letter","year":"2002","journal-title":"J. Anal. Toxicol."},{"issue":"2","key":"10.1016\/j.forsciint.2017.07.025_bib0135","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0379-0738(03)00179-8","article-title":"Tissue concentrations of MDMA and its metabolite MDA in three fatal cases of overdose","volume":"135","author":"Garcia-Repetto","year":"2003","journal-title":"Forensic Sci. Int."},{"issue":"5","key":"10.1016\/j.forsciint.2017.07.025_bib0140","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1093\/jat\/27.5.318","article-title":"Fatality due to combined use of the designer drugs MDMA and PMA: a distribution study","volume":"27","author":"Dams","year":"2003","journal-title":"J. Anal. Toxicol."},{"issue":"5","key":"10.1016\/j.forsciint.2017.07.025_bib0145","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/BF01369826","article-title":"Fatal poisoning by MDMA (ecstasy) and MDEA: a case report","volume":"108","author":"Fineschi","year":"1996","journal-title":"Int. J. Leg. Med."},{"issue":"4","key":"10.1016\/j.forsciint.2017.07.025_bib0150","doi-asserted-by":"crossref","first-page":"R136","DOI":"10.1186\/cc11441","article-title":"Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics","volume":"16","author":"Schulz","year":"2012","journal-title":"Crit. Care"},{"key":"10.1016\/j.forsciint.2017.07.025_bib0155","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1192\/bjp.130.3.244","article-title":"Psychiatric morbidity in a sample of accidents","volume":"130","author":"Holding","year":"1977","journal-title":"Br. J. Psychiatry: J. Mental Sci."},{"issue":"3\u20134","key":"10.1016\/j.forsciint.2017.07.025_bib0160","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0379-0738(85)90133-1","article-title":"Body fluid levels of lysergide (LSD)","volume":"28","author":"Smith","year":"1985","journal-title":"Forensic Sci. Int."},{"issue":"1\u20133","key":"10.1016\/j.forsciint.2017.07.025_bib0165","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.forsciint.2009.11.017","article-title":"Two cases of lysergamide intoxication by ingestion of seeds from Hawaiian Baby Woodrose","volume":"197","author":"Klinke","year":"2010","journal-title":"Forensic Sci. Int."}],"container-title":["Forensic Science International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0379073817302840?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0379073817302840?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T00:34:15Z","timestamp":1538008455000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0379073817302840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":33,"alternative-id":["S0379073817302840"],"URL":"https:\/\/doi.org\/10.1016\/j.forsciint.2017.07.025","relation":{},"ISSN":["0379-0738"],"issn-type":[{"type":"print","value":"0379-0738"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Advantages of analyzing postmortem brain samples in routine forensic drug screening\u2014Case series of three non-natural deaths tested positive for lysergic acid diethylamide (LSD)","name":"articletitle","label":"Article Title"},{"value":"Forensic Science International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.forsciint.2017.07.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}