{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T18:33:14Z","timestamp":1780079594866,"version":"3.54.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["15K08894"],"award-info":[{"award-number":["15K08894"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Forensic Science International"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.forsciint.2018.04.027","type":"journal-article","created":{"date-parts":[[2018,4,22]],"date-time":"2018-04-22T17:59:05Z","timestamp":1524419945000},"page":"23-28","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"special_numbering":"C","title":["Micro-segmental hair analysis for proving drug-facilitated crimes: Evidence that a victim ingested a sleeping aid, diphenhydramine, on a specific day"],"prefix":"10.1016","volume":"288","author":[{"given":"Kenji","family":"Kuwayama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maika","family":"Nariai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Miyaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko T.","family":"Iwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuyuki","family":"Kanamori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Tsujikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5880-2466","authenticated-orcid":false,"given":"Tadashi","family":"Yamamuro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Segawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaro","family":"Iwase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.forsciint.2018.04.027_bib0005","first-page":"83","article-title":"The use of miscellaneous prescription medications to facilitate sexual assault","volume":"22","author":"Couper","year":"2010","journal-title":"Forensic Sci. Rev."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0010","first-page":"15","article-title":"The use of alcohol to facilitate sexual assault","volume":"22","author":"Kerrigan","year":"2010","journal-title":"Forensic Sci. Rev."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0015","doi-asserted-by":"crossref","first-page":"e12","DOI":"10.1016\/j.forsciint.2016.12.010","article-title":"Detection of the antipsychotic drug quetiapine in the blood, urine and hair samples of the victim of a drug-facilitated sexual assault","volume":"270","author":"Johansen","year":"2017","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0020","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.drugpo.2017.07.010","article-title":"Hair testing to assess both known and unknown use of drugs amongst ecstasy users in the electronic dance music scene","volume":"48","author":"Palamar","year":"2017","journal-title":"Int. J. Drug Policy"},{"key":"10.1016\/j.forsciint.2018.04.027_bib0025","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.forsciint.2017.10.044","article-title":"The correlation between concentrations of zolpidem and benzodiazepines in segmental hair samples and use patterns","volume":"282","author":"Kim","year":"2018","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0030","article-title":"Hair testing of GHB: an everlasting issue in forensic toxicology","author":"Busard\u00f2","year":"2017","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0035","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jflm.2015.09.009","article-title":"Review Drug concentrations in hair and their relevance in drug facilitated crimes","volume":"36","author":"Xiang","year":"2015","journal-title":"J. Forensic Leg. Med."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0040","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s00414-011-0597-y","article-title":"Hair analysis of drugs involved in drug-facilitated sexual assault and detection of zolpidem in a suspected case","volume":"126","author":"Salomone","year":"2012","journal-title":"Int. J. Legal Med."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0045","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/FTD.0000000000000333","article-title":"Determination of antidepressants in hair via UHPLC-MS\/MS as a complementary informative tool for clinical and forensic toxicological assessments","volume":"38","author":"Ram\u00edrez","year":"2016","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0050","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s12917-016-0709-5","article-title":"Long-term monitoring of opioid, sedative and anti-inflammatory drugs in horse hair using a selective and sensitive LC-MS\/MS procedure","volume":"12","author":"Madry","year":"2016","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0055","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.forsciint.2015.06.029","article-title":"Relationship between methamphetamine use history and segmental hair analysis findings of MA users","volume":"254","author":"Han","year":"2015","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0060","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1002\/dta.1991","article-title":"Time-course measurements of drug concentrations in hair and toenails after single administrations of pharmaceutical products","volume":"9","author":"Kuwayama","year":"2017","journal-title":"Drug Test. Anal."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0065","series-title":"Hair and Hair Diseases","author":"Orfanos","year":"1990"},{"key":"10.1016\/j.forsciint.2018.04.027_bib0070","first-page":"5502","article-title":"Interest of single hair analysis to document drug exposure: literature review and a case report involving zuclopenthixol","volume":"23","author":"Allibe","year":"2017","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0075","doi-asserted-by":"crossref","first-page":"10328","DOI":"10.1021\/acs.analchem.6b03551","article-title":"Detection and mapping of cannabinoids in single hair samples through rapid derivatization and matrix-assisted laser desorption ionization mass spectrometry","volume":"88","author":"Beasley","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0080","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1021\/acs.analchem.5b03794","article-title":"Analysis of antiretrovirals in single hair strands for evaluation of drug adherence with infrared-matrix-assisted laser desorption electrospray ionization mass spectrometry imaging","volume":"88","author":"Rosen","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0085","doi-asserted-by":"crossref","first-page":"11758","DOI":"10.1021\/ac503193w","article-title":"Single hair analysis of small molecules using MALDI-triple quadrupole MS imaging and LC-MS\/MS: investigations on opportunities and pitfalls","volume":"86","author":"Poetzsch","year":"2014","journal-title":"Anal. Chem."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0090","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1007\/s00216-014-7898-1","article-title":"Mass imaging of ketamine in a single scalp hair by MALDI-FTMS","volume":"406","author":"Shen","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0095","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/dta.1453","article-title":"Determination of cocaine, cocaine metabolites and cannabinoids in single hairs by MALDI Fourier transform mass spectrometry\u2014preliminary results","volume":"5","author":"Musshoff","year":"2013","journal-title":"Drug Test Anal."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0100","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/jms.1908","article-title":"MALDI-TOF and MALDI-FTICR imaging mass spectrometry of methamphetamine incorporated into hair","volume":"46","author":"Miki","year":"2011","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0105","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s11419-011-0109-2","article-title":"Imaging of methamphetamine incorporated into hair by MALDI-TOF mass spectrometry","volume":"29","author":"Miki","year":"2011","journal-title":"Forensic Toxicol."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0110","doi-asserted-by":"crossref","first-page":"5476","DOI":"10.1021\/acs.analchem.5b00971","article-title":"Time-course mass spectrometry imaging for depicting drug incorporation into hair","volume":"87","author":"Kamata","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0115","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1124\/dmd.116.074211","article-title":"Incorporation of zolpidem into hair and its distribution after a single administration","volume":"45","author":"Shima","year":"2017","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0120","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.aca.2016.10.029","article-title":"Three-step drug extraction from a single sub-millimeter segment of hair and nail to determine the exact day of drug intake","volume":"948","author":"Kuwayama","year":"2016","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.forsciint.2018.04.027_bib0125","article-title":"Different localizations of drugs simultaneously administered in a strand of hair by micro-segmental analysis","author":"Kuwayama","year":"2017","journal-title":"Drug Test Anal."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0130","doi-asserted-by":"crossref","DOI":"10.1373\/jalm.2017.025346","article-title":"Accurate estimation of drug intake day by micro-segmental analysis of a strand of hair using internal temporal markers","author":"Kuwayama","year":"2018","journal-title":"J. Appl. Lab. Med."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0135","series-title":"Hair Analysis in Clinical and Forensic Toxicology","author":"Kintz","year":"2015"},{"key":"10.1016\/j.forsciint.2018.04.027_bib0140","unstructured":"https:\/\/www.drugs.com\/diphenhydramine.html."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0145","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/PAF.0000000000000106","article-title":"Diphenhydramine\u2019s role in death investigations: an examination of diphenhydramine prevalence in 2 US geographical areas","volume":"35","author":"Botch-Jones","year":"2014","journal-title":"Am. J. Forensic Med. Pathol."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0150","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.forsciint.2006.12.006","article-title":"Hair analysis for diphenhydramine after surreptitious administration to a child","volume":"173","author":"Kintz","year":"2007","journal-title":"Forensic Sci. Int"},{"key":"10.1016\/j.forsciint.2018.04.027_bib0155","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1093\/jat\/bkt054","article-title":"Scientific Working Group for Forensic Toxicology (SWGTOX) standard practices for method validation in forensic toxicology","volume":"37","author":"Scientific Working Group for Forensic Toxicology","year":"2013","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0160","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.forsciint.2017.11.004","article-title":"Role of hair pigmentation in drug incorporation into hair","volume":"281","author":"Yu","year":"2017","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.forsciint.2018.04.027_bib0165","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s11419-014-0256-3","article-title":"Comparison of sample preparation methods for zolpidem extraction from hair","volume":"33","author":"Miyaguchi","year":"2015","journal-title":"Forensic Toxicol."}],"container-title":["Forensic Science International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0379073818301853?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0379073818301853?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,27]],"date-time":"2019-06-27T14:22:42Z","timestamp":1561645362000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0379073818301853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":33,"alternative-id":["S0379073818301853"],"URL":"https:\/\/doi.org\/10.1016\/j.forsciint.2018.04.027","relation":{},"ISSN":["0379-0738"],"issn-type":[{"value":"0379-0738","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Micro-segmental hair analysis for proving drug-facilitated crimes: Evidence that a victim ingested a sleeping aid, diphenhydramine, on a specific day","name":"articletitle","label":"Article Title"},{"value":"Forensic Science International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.forsciint.2018.04.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}