{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T06:46:33Z","timestamp":1792565193822,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Forensic Science International"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.forsciint.2026.113136","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:50:40Z","timestamp":1789141840000},"page":"113136","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Can a single dose of cetirizine and meclizine be quantified in hair up to one year after intake?"],"prefix":"10.1016","volume":"389","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9669-2829","authenticated-orcid":false,"given":"Jan","family":"B\u00edlek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Katrine Klose","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Kronstrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9555-5134","authenticated-orcid":false,"given":"Sys Stybe","family":"Johansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.forsciint.2026.113136_bib1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jflm.2015.09.009","article-title":"Review: Drug concentrations in hair and their relevance in drug facilitated crimes","volume":"36","author":"Xiang","year":"2015","journal-title":"J. Forensic Leg. Med."},{"issue":"7","key":"10.1016\/j.forsciint.2026.113136_bib2","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1007\/s00216-007-1209-z","article-title":"Bioanalytical procedures for detection of chemical agents in hair in the case of drug-facilitated crimes","volume":"388","author":"Kintz","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"issue":"1\u20132","key":"10.1016\/j.forsciint.2026.113136_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.cca.2006.02.019","article-title":"State of the art in hair analysis for detection of drug and alcohol abuse","volume":"370","author":"Pragst","year":"2006","journal-title":"Clin. Chim. Acta Int. J. Clin. Chem."},{"issue":"2","key":"10.1016\/j.forsciint.2026.113136_bib4","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1080\/15563650.2017.1379603","article-title":"The interpretation of hair analysis for drugs and drug metabolites","volume":"56","author":"Cuypers","year":"2018","journal-title":"Clin. Toxicol."},{"issue":"36","key":"10.1016\/j.forsciint.2026.113136_bib5","doi-asserted-by":"crossref","DOI":"10.2174\/1381612823666170929155628","article-title":"Hair Analysis in Forensic Toxicology: An Updated Review with a Special Focus on Pitfalls","volume":"23","author":"Kintz","year":"2018","journal-title":"Curr. Pharm. Des."},{"issue":"1","key":"10.1016\/j.forsciint.2026.113136_bib6","doi-asserted-by":"crossref","DOI":"10.1002\/wfs2.1196","article-title":"Hair analysis in forensic toxicology","volume":"1","author":"Kintz","year":"2019","journal-title":"WIREs Forensic Sci."},{"issue":"1","key":"10.1016\/j.forsciint.2026.113136_bib7","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00414-016-1429-x","article-title":"Deposition of diazepam and its metabolites in hair following a single dose of diazepam","volume":"131","author":"Wang","year":"2017","journal-title":"Int. J. Leg. Med."},{"key":"10.1016\/j.forsciint.2026.113136_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2019.110074","article-title":"Distribution of zopiclone and main metabolites in hair following a single dose","volume":"306","author":"Hansen","year":"2020","journal-title":"Forensic Sci. Int."},{"issue":"6","key":"10.1016\/j.forsciint.2026.113136_bib9","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/jat\/bkt035","article-title":"Segmental Hair Analysis after a Single Dose of Zolpidem: Comparison with a Previous Study","volume":"37","author":"Cui","year":"2013","journal-title":"J. Anal. Toxicol."},{"issue":"5","key":"10.1016\/j.forsciint.2026.113136_bib10","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1520\/JFS15113J","article-title":"Deposition of 7-Aminoflunitrazepam and Flunitrazepam in Hair After a Single Dose of Rohypnol\u00ae","volume":"46","author":"Negrusz","year":"2001","journal-title":"J. Forensic Sci."},{"issue":"7","key":"10.1016\/j.forsciint.2026.113136_bib11","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1093\/jat\/26.7.471","article-title":"Deposition of 7-Aminoclonazepam and Clonazepam in Hair Following a Single Dose of Klonopin","volume":"26","author":"Negrusz","year":"2002","journal-title":"J. Anal. Toxicol."},{"issue":"1\u20133","key":"10.1016\/j.forsciint.2026.113136_bib12","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.forsciint.2010.04.046","article-title":"Segmental hair analysis using liquid chromatography\u2013tandem mass spectrometry after a single dose of benzodiazepines","volume":"204","author":"Xiang","year":"2011","journal-title":"Forensic Sci. Int."},{"issue":"5","key":"10.1016\/j.forsciint.2026.113136_bib13","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/dta.1679","article-title":"Determination of GHB in human hair by HPLC-MS\/MS: Development and validation of a method and application to a study group and three possible single exposure cases","volume":"7","author":"Bertol","year":"2015","journal-title":"Drug. Test. Anal."},{"issue":"6","key":"10.1016\/j.forsciint.2026.113136_bib14","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1007\/s00414-010-0534-5","article-title":"Disposition of ketamine and norketamine in hair after a single dose","volume":"125","author":"Xiang","year":"2011","journal-title":"Int. J. Leg. Med."},{"key":"10.1016\/j.forsciint.2026.113136_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2020.110546","article-title":"Temporal patterns of tramadol in hair after a single dose","volume":"316","author":"Johansen","year":"2020","journal-title":"Forensic Sci. Int."},{"issue":"5","key":"10.1016\/j.forsciint.2026.113136_bib16","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s002280050129","article-title":"Codeine disposition in human hair after single and multiple doses","volume":"50","author":"Rollins","year":"1996","journal-title":"Eur. J. Clin. Pharmacol."},{"issue":"9","key":"10.1016\/j.forsciint.2026.113136_bib17","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1093\/clinchem\/45.9.1485","article-title":"Codeine Concentration in Hair after Oral Administration Is Dependent on Melanin Content","volume":"45","author":"Kronstrand","year":"1999","journal-title":"Clin. Chem."},{"issue":"4","key":"10.1016\/j.forsciint.2026.113136_bib18","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1002\/dta.2259","article-title":"Different localizations of drugs simultaneously administered in a strand of hair by micro-segmental analysis","volume":"10","author":"Kuwayama","year":"2018","journal-title":"Drug. Test. Anal."},{"key":"10.1016\/j.forsciint.2026.113136_bib19","doi-asserted-by":"crossref","DOI":"10.1097\/FTD.0000000000001461","article-title":"Testing for hydroxyzine in human hair after a single controlled administration: First quantitative data","author":"Arbouche","year":"2026","journal-title":"Ther. Drug. Monit."},{"issue":"7","key":"10.1016\/j.forsciint.2026.113136_bib20","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1002\/dta.70084","article-title":"Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose","volume":"18","author":"B\u00edlek","year":"2026","journal-title":"Drug. Test. Anal."},{"key":"10.1016\/j.forsciint.2026.113136_bib21","series-title":"Toxicological aspects of drug-facilitated crimes","year":"2014"},{"issue":"9","key":"10.1016\/j.forsciint.2026.113136_bib22","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1177\/0091270011414575","article-title":"Meclizine Metabolism and Pharmacokinetics: Formulation on Its Absorption","volume":"52","author":"Wang","year":"2012","journal-title":"J. Clin. Pharmacol."},{"issue":"21","key":"10.1016\/j.forsciint.2026.113136_bib23","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.2174\/092986708785747625","article-title":"Physicochemical, Pharmacological and Pharmacokinetic Properties of the Zwitterionic Antihistamines Cetirizine and Levocetirizine","volume":"15","author":"Chen","year":"2008","journal-title":"Curr. Med. Chem."},{"issue":"12","key":"10.1016\/j.forsciint.2026.113136_bib24","doi-asserted-by":"crossref","first-page":"3987","DOI":"10.1007\/s00204-024-03867-3","article-title":"Development of two ultra-sensitive UHPLC\u2013QqQ-MS\/MS methods for the simultaneous determination of hydroxyzine and its active metabolite (cetirizine) in human blood: applications to real cases of forensic toxicology","volume":"98","author":"Ch\u0142opa\u015b-Konowa\u0142ek","year":"2024","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.forsciint.2026.113136_bib25","doi-asserted-by":"crossref","first-page":"270.e1","DOI":"10.1016\/j.ajem.2021.08.062","article-title":"Unintentional cetirizine overdose causing anticholinergic syndrome","volume":"52","author":"Renko","year":"2022","journal-title":"Am. J. Emerg. Med."},{"issue":"3","key":"10.1016\/j.forsciint.2026.113136_bib26","first-page":"228","article-title":"Cetirizine-induced hepatotoxicity: case series and review of the literature","volume":"6","author":"Coskun","year":"2018","journal-title":"Gastroenterol. Rep."},{"issue":"2","key":"10.1016\/j.forsciint.2026.113136_bib27","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1093\/jat\/bkt100","article-title":"Suicide Due to Cyclizine Overdose","volume":"38","author":"Arnestad","year":"2014","journal-title":"J. Anal. Toxicol."},{"issue":"8","key":"10.1016\/j.forsciint.2026.113136_bib28","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/dta.2130","article-title":"Targeted analysis of 116 drugs in hair by UHPLC-MS\/MS and its application to forensic cases","volume":"9","author":"Wang","year":"2017","journal-title":"Drug. Test. Anal."},{"issue":"1\u20133","key":"10.1016\/j.forsciint.2026.113136_bib29","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.forsciint.2011.10.024","article-title":"Society of Hair Testing guidelines for drug testing in hair","volume":"218","author":"Cooper","year":"2012","journal-title":"Forensic Sci. Int."},{"issue":"9","key":"10.1016\/j.forsciint.2026.113136_bib30","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1002\/dta.3526","article-title":"The Society of Hair Testing consensus on general recommendations for hair testing and drugs of abuse testing in hair","volume":"15","author":"Favretto","year":"2023","journal-title":"Drug. Test. Anal."},{"issue":"4","key":"10.1016\/j.forsciint.2026.113136_bib31","doi-asserted-by":"crossref","DOI":"10.1093\/jat\/bkz115","article-title":"ANSI\/ASB Standard 036 for Method Validation in Forensic Toxicology Has Replaced SWGTOX\u2019s Version","volume":"44","author":"LeBeau","year":"2020","journal-title":"J. Anal. Toxicol."},{"issue":"36","key":"10.1016\/j.forsciint.2026.113136_bib32","first-page":"5442","article-title":"Update of Standard Practices for New Method Validation in Forensic Toxicology","volume":"23","author":"Wille","year":"2017","journal-title":"Curr. Pharm. Des."},{"issue":"4","key":"10.1016\/j.forsciint.2026.113136_bib33","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1046\/j.1472-8206.2001.00035.x","article-title":"Absorption and disposition of levocetirizine, the eutomer of cetirizine, administered alone or as cetirizine to healthy volunteers","volume":"15","author":"Baltes","year":"2001","journal-title":"Fundam. Clin. Pharmacol."},{"issue":"09","key":"10.1016\/j.forsciint.2026.113136_bib34","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1055\/s-0031-1296422","article-title":"Pharmacokinetics and Bioequivalence Study of Two Cetirizine Hydrochloride Formulations in Healthy Chinese Male Volunteers","volume":"59","author":"Xu","year":"2011","journal-title":"Arzneimittelforschung"},{"key":"10.1016\/j.forsciint.2026.113136_bib35","series-title":"The Practice of Medicinal Chemistry","first-page":"539","article-title":"Physiological Aspects Determining the Pharmacokinetic Properties of Drugs","author":"Boussery","year":"2008"}],"container-title":["Forensic Science International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0379073826003245?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0379073826003245?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T06:22:52Z","timestamp":1792563772000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0379073826003245"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":35,"alternative-id":["S0379073826003245"],"URL":"https:\/\/doi.org\/10.1016\/j.forsciint.2026.113136","relation":{},"ISSN":["0379-0738"],"issn-type":[{"value":"0379-0738","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Can a single dose of cetirizine and meclizine be quantified in hair up to one year after intake?","name":"articletitle","label":"Article Title"},{"value":"Forensic Science International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.forsciint.2026.113136","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"113136"}}