{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:07:00Z","timestamp":1785773220709,"version":"3.56.0"},"reference-count":69,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["facialplastic.theclinics.com","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Facial Plastic Surgery Clinics of North America"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.fsc.2015.01.010","type":"journal-article","created":{"date-parts":[[2015,4,23]],"date-time":"2015-04-23T06:15:55Z","timestamp":1429769755000},"page":"243-255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["The Role of Neurotoxins in the Periorbital and Midfacial Areas"],"prefix":"10.1016","volume":"23","author":[{"given":"Benjamin P.","family":"Erickson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy W.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa D.","family":"Grunebaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsc.2015.01.010_bib1","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/S0161-6420(80)35127-0","article-title":"Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery","volume":"87","author":"Scott","year":"1980","journal-title":"Ophthalmology"},{"key":"10.1016\/j.fsc.2015.01.010_bib2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1524-4725.1992.tb03295.x","article-title":"Treatment of glabellar frown lines with C. Botulinum A exotoxin","volume":"18","author":"Carruthers","year":"1992","journal-title":"J\u00a0Dermatol Surg Oncol"},{"issue":"10","key":"10.1016\/j.fsc.2015.01.010_bib3","first-page":"1434","article-title":"Botulinum toxin in men: review of relevant anatomy and clinical trial data","volume":"39","author":"Keaney","year":"2013","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib4","unstructured":"American Society of Plastic Surgeons. 2013 Plastic surgery statistics report. Web. November 8, 2014."},{"issue":"3","key":"10.1016\/j.fsc.2015.01.010_bib5","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/phar.1196","article-title":"Abo-, inco-, ona-, and rima-botulinum toxins in clinical therapy: a primer","volume":"33","author":"Chen","year":"2013","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.fsc.2015.01.010_bib6","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1080\/09638280701568296","article-title":"Pharmacology of therapeutic botulinum toxin preparations","volume":"29","author":"Dressler","year":"2007","journal-title":"Disabil Rehabil"},{"issue":"1","key":"10.1016\/j.fsc.2015.01.010_bib7","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1473-2165.2010.00545.x","article-title":"A\u00a0succinct review of botulinum toxin in dermatology; update of cosmetic and noncosmetic use","volume":"10","author":"Feily","year":"2011","journal-title":"J\u00a0Cosmet Dermatol"},{"issue":"1 Suppl","key":"10.1016\/j.fsc.2015.01.010_bib8","first-page":"23S","article-title":"IncobotulinumtoxinA in clinical literature","volume":"33","author":"Lorenc","year":"2013","journal-title":"Aesthet Surg J"},{"issue":"3","key":"10.1016\/j.fsc.2015.01.010_bib9","doi-asserted-by":"crossref","first-page":"183","DOI":"10.2165\/11530110-000000000-00000","article-title":"Botulinum toxin: examining duration of effect in facial aesthetic applications","volume":"11","author":"Flynn","year":"2010","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.fsc.2015.01.010_bib10","doi-asserted-by":"crossref","first-page":"14316","DOI":"10.1021\/bi701564f","article-title":"Comparative role of neurotoxin-associated proteins in the structural stability and endopeptidase activity of botulinum neurotoxin complex A and E","volume":"46","author":"Kukreja","year":"2007","journal-title":"Biochemistry"},{"issue":"3","key":"10.1016\/j.fsc.2015.01.010_bib11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/IIO.0b013e31828c0472","article-title":"Update on botulinum toxins in oculofacial plastic surgery","volume":"53","author":"Giacometti","year":"2013","journal-title":"Int Ophthalmol Clin"},{"issue":"1","key":"10.1016\/j.fsc.2015.01.010_bib12","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1473-2165.2011.00593.x","article-title":"Advances in the use of botulinum neurotoxins in facial esthetics","volume":"11","author":"Flynn","year":"2012","journal-title":"J\u00a0Cosmet Dermatol"},{"issue":"1","key":"10.1016\/j.fsc.2015.01.010_bib13","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.clindermatol.2003.12.026","article-title":"Contraindications and complications with the use of botulinum toxin","volume":"22","author":"Klein","year":"2004","journal-title":"Clin Dermatol"},{"issue":"3","key":"10.1016\/j.fsc.2015.01.010_bib14","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1001\/archderm.142.3.320","article-title":"Efficacy and safety of 3- and 5-injection patterns (30 and 50 U) of botulinum toxin A (Dysport) for the treatment of wrinkles in the glabella and the central forehead region","volume":"142","author":"Rzany","year":"2006","journal-title":"Arch Dermatol"},{"issue":"4","key":"10.1016\/j.fsc.2015.01.010_bib15","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.det.2009.08.001","article-title":"Botulinum toxin in facial rejuvenation: an update","volume":"27","author":"Carruthers","year":"2009","journal-title":"Dermatol Clin"},{"issue":"4","key":"10.1016\/j.fsc.2015.01.010_bib16","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/jocd.12059","article-title":"Treatment of forehead\/glabellar rhytide complex with combination botulinum toxin a and hyaluronic acid versus botulinum toxin A injection alone: a split-face, rater-blinded, randomized control trial","volume":"12","author":"Dubina","year":"2013","journal-title":"J\u00a0Cosmet Dermatol"},{"issue":"5","key":"10.1016\/j.fsc.2015.01.010_bib17","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/ICU.0b013e32833ce7bc","article-title":"Update on botulinum toxin and dermal fillers","volume":"21","author":"Berbos","year":"2010","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.fsc.2015.01.010_bib18","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1111\/j.1524-4725.1998.tb04106.x","article-title":"Complications of botulinum A exotoxin for hyperfunctional lines","volume":"24","author":"Matarasso","year":"1998","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib19","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/14764170260030126","article-title":"Botulinum B treatment of the glabellar and frontalis regions: a dose response analysis","volume":"4","author":"Spencer","year":"2002","journal-title":"J\u00a0Cosmet Laser Ther"},{"key":"10.1016\/j.fsc.2015.01.010_bib20","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/2046-4053-2-40","article-title":"A\u00a0comparative assessment of three formulations of botulinum toxin A for facial rhytides: a systematic review and meta-analyses","volume":"2","author":"Bonaparte","year":"2013","journal-title":"Syst Rev"},{"key":"10.1016\/j.fsc.2015.01.010_bib21","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/026119291003800401","article-title":"The current scientific and legal status of alternative methods to the LD50 test for botulinum neurotoxin potency testing","volume":"38","author":"Adler","year":"2010","journal-title":"Altern Lab Anim"},{"issue":"2","key":"10.1016\/j.fsc.2015.01.010_bib22","first-page":"31","article-title":"Comparison and overview of currently available neurotoxins","volume":"7","author":"Walker","year":"2014","journal-title":"J\u00a0Clin Aesthet Dermatol"},{"key":"10.1016\/j.fsc.2015.01.010_bib23","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.toxicon.2008.04.038","article-title":"Xeomin\u00ae is stable without refrigeration: complexing proteins are not required for stability of botulinum toxin type A preparations","volume":"51","author":"Grein","year":"2008","journal-title":"Toxicon"},{"issue":"1","key":"10.1016\/j.fsc.2015.01.010_bib24","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1504\/TBJ.2011.041815","article-title":"Stability of botulinum neurotoxin type A, devoid of complexing proteins","volume":"2","author":"Grein","year":"2011","journal-title":"Botulinum J"},{"key":"10.1016\/j.fsc.2015.01.010_bib25","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2147\/CCID.S26550","article-title":"Botulinum toxin type A treatment to the upper face: retrospective analysis of daily practice","volume":"5","author":"Prager","year":"2012","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"10.1016\/j.fsc.2015.01.010_bib26","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1111\/j.1524-4725.2010.01706.x","article-title":"Noninferiority of incobotulinumtoxinA, free from complexing proteins, compared with another botulinum toxin type A in the treatment of glabellar frown lines","volume":"36","author":"Sattler","year":"2010","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib27","doi-asserted-by":"crossref","first-page":"669","DOI":"10.2165\/00003495-200767050-00003","article-title":"Botulinum neurotoxin type A free of complexing proteins (XEOMIN) in focal dystonia","volume":"67","author":"Jost","year":"2007","journal-title":"Drugs"},{"key":"10.1016\/j.fsc.2015.01.010_bib28","series-title":"Scientific and therapeutic aspects of botulinum toxin","first-page":"409","article-title":"Botulinum toxin: clinical implications of antigenicity and immunoresistance","author":"Jankovic","year":"2002"},{"key":"10.1016\/j.fsc.2015.01.010_bib29","doi-asserted-by":"crossref","first-page":"3739","DOI":"10.1099\/mic.0.28421-0","article-title":"Production of antineurotoxin antibody is enhanced by two subcomponents, HA1 and HA3b, of Clostridium botulinum type B 16S toxin-haemagglutinin","volume":"151","author":"Lee","year":"2005","journal-title":"Microbiology"},{"issue":"6","key":"10.1016\/j.fsc.2015.01.010_bib30","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.jaad.2006.07.006","article-title":"Comparison of two formulations of botulinum toxin type A for the treatment of glabellar lines: a double-blind, randomized study","volume":"55","author":"Lowe","year":"2006","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"Suppl 5","key":"10.1016\/j.fsc.2015.01.010_bib31","first-page":"S22","article-title":"The biochemistry of botulinum toxin type B","volume":"55","author":"Setler","year":"2000","journal-title":"Neurology"},{"issue":"11","key":"10.1016\/j.fsc.2015.01.010_bib32","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1111\/j.1524-4725.2011.02087.x","article-title":"Handling botulinum toxins: an updated literature review","volume":"37","author":"Trindade De Almeida","year":"2011","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib33","first-page":"519","article-title":"Botulinum toxin type B (MYOBLOC) versus botulinum toxin type A (BOTOX) frontalis study: rate of onset and radius of diffusion","volume":"29","author":"Flynn","year":"2003","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib34","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1067\/mhn.2002.124706","article-title":"Botulinum toxin type B (MyoBloc) in the management of hyperkinetic facial lines","volume":"126","author":"Ramirez","year":"2002","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"Suppl 1","key":"10.1016\/j.fsc.2015.01.010_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1468-1331.2006.01439.x","article-title":"Immunological aspects of Botox, Dysport and Myobloc\/NeuroBloc","volume":"13","author":"Dressler","year":"2006","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.fsc.2015.01.010_bib36","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1002\/mds.22157","article-title":"Long-term treatment with botulinum toxin type A in cervical dystonia has low immunogenicity by mouse protection assay","volume":"23","author":"Brin","year":"2008","journal-title":"Mov Disord"},{"key":"10.1016\/j.fsc.2015.01.010_bib37","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1111\/j.1524-4725.2010.01702.x","article-title":"Botulinum toxin A: is it really a fragile molecule?","volume":"36","author":"Shome","year":"2010","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib38","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/IOP.0b013e3181607475","article-title":"Botox: shaken, not stirred","volume":"24","author":"Kazim","year":"2008","journal-title":"Ophthal Plast Reconstr Surg"},{"issue":"6Suppl","key":"10.1016\/j.fsc.2015.01.010_bib39","first-page":"2S","article-title":"Consensus recommendations on the use of botulinum toxin Type A in facial aesthetics","volume":"114","author":"(Walker 25) Carruthers","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib40","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1001\/archderm.138.4.510","article-title":"Pain associated with injection of botulinum A exotoxin reconstituted using isotonic sodium chloride with and without preservative: a double-blind, randomized controlled trial","volume":"138","author":"Alam","year":"2002","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.fsc.2015.01.010_bib41","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s00266-004-0062-0","article-title":"Evaluating effects of preservative-containing saline solution on pain perception during botulinum toxin type-a injections at different locations: a prospective, single-blinded, randomized controlled trial","volume":"29","author":"Sarifakioglu","year":"2005","journal-title":"Aesthetic Plast Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib42","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0025-6196(11)64616-8","article-title":"Addition of an anesthetic agent to enhance the predictability of the effects of botulinum toxin type A injections: a randomized controlled study","volume":"75","author":"Gassner","year":"2000","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.fsc.2015.01.010_bib43","first-page":"764","article-title":"Simultaneous injection of lidocaine improves predictability of effect of botulinum toxin","volume":"88","author":"Haubner","year":"2009","journal-title":"Laryngorhinootologie"},{"key":"10.1016\/j.fsc.2015.01.010_bib44","first-page":"523","article-title":"Multicenter, double-blind study of the efficacy of injections with botulinum toxin type A reconstituted up to six consecutive weeks before application","volume":"29","author":"Hexsel","year":"2003","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib45","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2147\/CCID.S6492","article-title":"Botulinum toxin type A for the management of glabellar rhytids","volume":"3","author":"Tremaine","year":"2010","journal-title":"Clin Cosmet Investig Dermatol"},{"issue":"6","key":"10.1016\/j.fsc.2015.01.010_bib46","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/IOP.0b013e31815793b7","article-title":"Efficacy of fresh versus refrigerated botulinum toxin in the treatment of lateral periorbital rhytids","volume":"23","author":"Hui","year":"2007","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib47","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.jaad.2011.10.008","article-title":"Recommendations and current practices for the reconstitution and storage of botulinum toxin type A","volume":"67","author":"Liu","year":"2012","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"4","key":"10.1016\/j.fsc.2015.01.010_bib48","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1473-2165.2005.00207.x","article-title":"Botulinum toxin - an update on its use in facial rejuvenation","volume":"4","author":"Lehrer","year":"2005","journal-title":"J\u00a0Cosmet Dermatol"},{"key":"10.1016\/j.fsc.2015.01.010_bib49","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1111\/j.1524-4725.2006.32339.x","article-title":"Dilution volume of botulinum toxin type A for the treatment of glabellar rhytides: does it matter?","volume":"33","author":"Carruthers","year":"2007","journal-title":"Dermatol Surg"},{"issue":"10","key":"10.1016\/j.fsc.2015.01.010_bib50","first-page":"49","article-title":"Two cases of herpes zoster appearing after botulinum toxin type A injections","volume":"4","author":"Graber","year":"2011","journal-title":"J\u00a0Clin Aesthet Dermatol"},{"key":"10.1016\/j.fsc.2015.01.010_bib51","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1046\/j.1524-4725.2000.99147.x","article-title":"Browlift with botulinum toxin","volume":"26","author":"Huang","year":"2000","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib52","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/archotol.124.3.321","article-title":"Chemical browlift","volume":"124","author":"Frankel","year":"1998","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"12","key":"10.1016\/j.fsc.2015.01.010_bib53","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1111\/dsu.12317","article-title":"Consensus recommendations on the aesthetic usage of botulinum toxin type A in Asians","volume":"39","author":"Ahn","year":"2013","journal-title":"Dermatol Surg"},{"issue":"3","key":"10.1016\/j.fsc.2015.01.010_bib54","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1001\/jamafacial.2013.2458","article-title":"Subcutaneous vs. intramuscular botulinum toxin: split-face randomized study","volume":"16","author":"Gordin","year":"2014","journal-title":"JAMA Facial Plast Surg"},{"issue":"1 Spec No","key":"10.1016\/j.fsc.2015.01.010_bib55","doi-asserted-by":"crossref","first-page":"S51","DOI":"10.1111\/j.1524-4725.2006.32332.x","article-title":"A\u00a0randomized, double-blind, placebo-controlled study of botulinum toxin type A for the treatment of glabellar lines: determination of optimal dose","volume":"33","author":"Monheit","year":"2007","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib56","first-page":"508","article-title":"A\u00a0double-blinded, randomized, placebo-controlled pilot study of the safety and efficacy of Myobloc (botulinum toxin type B)-purified neurotoxin complex for the treatment of crow\u2019s feet: a double-blinded, placebo-controlled trial","volume":"29","author":"Baumann","year":"2003","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib57","first-page":"703","article-title":"Botulinum-A toxin treatment of the lower eyelid improves infraorbital rhytides and widens the eye","volume":"27","author":"Flynn","year":"2001","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib58","first-page":"943","article-title":"Botulinum A toxin (BOTOX) in the lower eyelid: dosefinding study","volume":"29","author":"Flynn","year":"2003","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib59","first-page":"596","article-title":"Botulinum toxin a in the treatment of dermatochalasis: an open-label, randomized, dose comparison study","volume":"5","author":"Cohen","year":"2006","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"5","key":"10.1016\/j.fsc.2015.01.010_bib60","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/dsu.12463","article-title":"Safety of botulinum toxin A in aesthetic treatments: a systematic review of clinical studies","volume":"40","author":"Cavallini","year":"2014","journal-title":"Dermatol Surg"},{"issue":"4","key":"10.1016\/j.fsc.2015.01.010_bib61","first-page":"1089","article-title":"Double-blind, placebo-controlled study of the safety and efficacy of botulinum toxin type A for patients with glabellar lines","volume":"112","author":"Carruthers","year":"2003","journal-title":"Plast Reconstr Surg"},{"issue":"6","key":"10.1016\/j.fsc.2015.01.010_bib62","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1067\/mjd.2002.121356","article-title":"A\u00a0multicenter, double-blind, randomized, placebo-controlled study of the efficacy and safety of botulinum toxin type A in the treatment of glabellar lines","volume":"46","author":"Carruthers","year":"2002","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.fsc.2015.01.010_bib63","first-page":"549","article-title":"Complications, adverse reactions, and insights with the use of botulinum toxin","volume":"29","author":"Klein","year":"2003","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.fsc.2015.01.010_bib64","doi-asserted-by":"crossref","first-page":"11","DOI":"10.2147\/CCID.S51938","article-title":"Neutralizing antibodies to botulinum neurotoxin type A in aesthetic medicine: five case reports","volume":"7","author":"Torres","year":"2013","journal-title":"Clin Cosmet Investig Dermatol"},{"issue":"2","key":"10.1016\/j.fsc.2015.01.010_bib65","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00702-012-0893-9","article-title":"Immunogenicity of botulinum toxins","volume":"120","author":"Naumann","year":"2013","journal-title":"J\u00a0Neural Transm"},{"key":"10.1016\/j.fsc.2015.01.010_bib66","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1016\/S0041-0101(01)00101-5","article-title":"A\u00a0comparison of the safety margins of botulinum neurotoxin serotypes A, B, and F in mice","volume":"39","author":"Aoki","year":"2001","journal-title":"Toxicon"},{"key":"10.1016\/j.fsc.2015.01.010_bib67","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1212\/01.WNL.0000055087.96356.BB","article-title":"Comparison of efficacy and immunogenicity of original versus current botulinum toxin cervical dystonia","volume":"60","author":"Jankovic","year":"2003","journal-title":"Neurology"},{"issue":"9","key":"10.1016\/j.fsc.2015.01.010_bib68","first-page":"968","article-title":"The frontalis activity measurement standard: a novel contralateral method for assessing botulinum neurotoxin type-A activity","volume":"10","author":"Nestor","year":"2011","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"10","key":"10.1016\/j.fsc.2015.01.010_bib69","first-page":"1148","article-title":"Comparing the clinical attributes of abobotulinumtoxinA and onabotulinumtoxinA utilizing a novel contralateral frontalis model and the frontalis activity measurement standard","volume":"10","author":"Nestor","year":"2011","journal-title":"J\u00a0Drugs Dermatol"}],"container-title":["Facial Plastic Surgery Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064740615000115?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064740615000115?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T22:14:03Z","timestamp":1651788843000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1064740615000115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":69,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S1064740615000115"],"URL":"https:\/\/doi.org\/10.1016\/j.fsc.2015.01.010","relation":{},"ISSN":["1064-7406"],"issn-type":[{"value":"1064-7406","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Role of Neurotoxins in the Periorbital and Midfacial Areas","name":"articletitle","label":"Article Title"},{"value":"Facial Plastic Surgery Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsc.2015.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}