{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T02:12:03Z","timestamp":1768270323297,"version":"3.49.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1016\/j.fsi.2012.02.018","type":"journal-article","created":{"date-parts":[[2012,2,21]],"date-time":"2012-02-21T21:04:51Z","timestamp":1329858291000},"page":"899-908","source":"Crossref","is-referenced-by-count":66,"title":["Molecular cloning and characterization of nucleotide binding and oligomerization domain-1 (NOD1) receptor in the Indian Major Carp, rohu (Labeo rohita), and analysis of its inductive expression and down-stream signalling molecules following ligands exposure and Gram-negative bacterial infections"],"prefix":"10.1016","volume":"32","author":[{"given":"Banikalyan","family":"Swain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhubanti","family":"Basu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mrinal","family":"Samanta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2012.02.018_bib1","first-page":"263","article-title":"Molecular innate immunity in Teleost fish: review and future perspectives","author":"Aoki","year":"2008","journal-title":"5th world fisheries congress"},{"key":"10.1016\/j.fsi.2012.02.018_bib2","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.cell.2006.02.015","article-title":"Pathogen recognition and innate immunity","volume":"124","author":"Akira","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.fsi.2012.02.018_bib3","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.fsi.2004.09.006","article-title":"Innate immunity of fish (overview)","volume":"20","author":"Magnadottir","year":"2006","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib4","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0092-8674(00)80412-2","article-title":"Innate immunity: the virtues of a nonclonal system of recognition","volume":"91","author":"Medzhitov","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.fsi.2012.02.018_bib5","doi-asserted-by":"crossref","first-page":"792","DOI":"10.4049\/jimmunol.0900173","article-title":"Cutting edge: TNF-\u03b1 mediated sensitization to ATP and Silica via the NLRP3 inflammasome in the absence of microbial stimulation","volume":"183","author":"Franchi","year":"2009","journal-title":"J\u00a0Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib6","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1146\/annurev.pathol.4.110807.092239","article-title":"NOD-like receptors: role in innate immunity and inflammatory disease","volume":"4","author":"Chen","year":"2009","journal-title":"Annu Rev Pathol Mech"},{"key":"10.1016\/j.fsi.2012.02.018_bib7","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.molimm.2004.06.012","article-title":"Toll-like receptors and Nod proteins in bacterial infection","volume":"41","author":"Philpott","year":"2004","journal-title":"Mol Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib8","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.cyto.2008.07.013","article-title":"The microbial and danger signals that activate NOD-like receptors","volume":"43","author":"Benko","year":"2008","journal-title":"Cytokine"},{"key":"10.1016\/j.fsi.2012.02.018_bib9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1189\/jlb.0607402","article-title":"NLR proteins: integral members of innate immunity and mediators of inflammatory diseases","volume":"83","author":"Wilmanski","year":"2008","journal-title":"J\u00a0Leukoc Biol"},{"key":"10.1016\/j.fsi.2012.02.018_bib10","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.immuni.2008.02.005","article-title":"The NLR gene family: a standard nomenclature","volume":"28","author":"Ting","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.fsi.2012.02.018_bib11","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1160\/TH09-05-0323","article-title":"Roll of Toll-like receptors, NOD-like receptors and RIG-I-like receptors in endothelial cells and systemic infections","volume":"102","author":"Opitz","year":"2009","journal-title":"J\u00a0Thromb Haemost"},{"key":"10.1016\/j.fsi.2012.02.018_bib12","doi-asserted-by":"crossref","first-page":"e2119","DOI":"10.1371\/journal.pone.0002119","article-title":"The NOD-like receptor (NLR) family: a tale of similarities and differences","volume":"3","author":"Proell","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1016\/j.fsi.2012.02.018_bib13","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1038\/ni1412","article-title":"NOD-like proteins in immunity, inflammation and disease","volume":"7","author":"Fritz","year":"2006","journal-title":"Nat Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib14","doi-asserted-by":"crossref","first-page":"14560","DOI":"10.1074\/jbc.274.21.14560","article-title":"Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB","volume":"274","author":"Inohara","year":"1999","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.fsi.2012.02.018_bib15","doi-asserted-by":"crossref","first-page":"12955","DOI":"10.1074\/jbc.274.19.12955","article-title":"Human CARD4 protein is a novel CED-4\/Apaf-1 cell death family member that activates NF-kappaB","volume":"274","author":"Bertin","year":"1999","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.fsi.2012.02.018_bib16","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1126\/science.1084677","article-title":"Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan","volume":"300","author":"Girardin","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.fsi.2012.02.018_bib17","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/ni945","article-title":"An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid","volume":"4","author":"Chamaillard","year":"2003","journal-title":"Nat Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbrc.2006.11.122","article-title":"Crystal structure of the Nod1 caspase activation and recruitment domain","volume":"353","author":"Coussens","year":"2007","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.fsi.2012.02.018_bib19","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1042\/BST0351479","article-title":"NOD1 and NOD2 in innate immunity and human inflammatory disorders","volume":"35","author":"Bourhis","year":"2007","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.fsi.2012.02.018_bib20","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.tibs.2009.06.011","article-title":"Activating immunity: lessons from the TLRs and NLRs","volume":"34","author":"Monie","year":"2009","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.fsi.2012.02.018_bib21","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.molimm.2009.09.030","article-title":"Influence of polymorphisms in porcine NOD2 on ligand recognition","volume":"47","author":"Jozaki","year":"2009","journal-title":"Mol Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib22","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.fsi.2009.09.012","article-title":"Molecular characterization and expression analysis of nuclear oligomerisation domain proteins NOD1 and NOD2 in grass carp Ctenopharyngodon idella","volume":"28","author":"Chen","year":"2010","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib23","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/sj.emboj.7601962","article-title":"A\u00a0critical role of RICK\/RIP2 polyubiquitination in Nod-induced NF-\u03baB activation","volume":"27","author":"Hasegawa","year":"2008","journal-title":"EMBO J"},{"key":"10.1016\/j.fsi.2012.02.018_bib24","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1167\/iovs.08-2756","article-title":"Nucleotide oligomerization Domain-2 (NOD-2) induced Uveitis: dependancy on IFN-\u03b3","volume":"50","author":"Rosenzweig","year":"2009","journal-title":"Invest Opthalmol Vis Sci"},{"key":"10.1016\/j.fsi.2012.02.018_bib25","doi-asserted-by":"crossref","first-page":"27823","DOI":"10.1074\/jbc.M003415200","article-title":"An induced proximity model for NF-kB activation in the Nod1\/RICK and RIP signaling pathway","volume":"275","author":"Inohara","year":"2000","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.fsi.2012.02.018_bib26","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1053\/gast.2003.50153","article-title":"CARD15\/NOD2 functions as an antibacterial factor in human intestinal epithelial cells","volume":"124","author":"Hisamatsu","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.fsi.2012.02.018_bib27","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1074\/jbc.M511044200","article-title":"NOD2\/CARD 15 mediates induction of the antimicrobial peptide human beta-defensin-2","volume":"281","author":"Voss","year":"2006","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.fsi.2012.02.018_bib28","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/s00011-003-1170-z","article-title":"Cloning, sequencing and expressional analysis of the mouse NOD2\/CARD15 gene","volume":"52","author":"Iwanaga","year":"2003","journal-title":"Inflamm Res"},{"key":"10.1016\/j.fsi.2012.02.018_bib29","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.molimm.2007.09.029","article-title":"Molecular cloning and functional characterization of porcine Nucleotide-binding oligomerization domain-1 (NOD1) recognizing minimum agonists, meso- diaminopimelic acid and meso-lanthionine","volume":"45","author":"Tohno","year":"2008","journal-title":"Mol Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib30","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1471-2148-8-42","article-title":"A\u00a0genomic review of the NOD-like receptor family in teleost fish: identification of novel NLR subfamily in Zebrafish","volume":"8","author":"Laing","year":"2008","journal-title":"BMC Evo Biol"},{"key":"10.1016\/j.fsi.2012.02.018_bib31","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.006122","article-title":"The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish","author":"Oehlers","year":"2011","journal-title":"Dis Models Mech"},{"key":"10.1016\/j.fsi.2012.02.018_bib32","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.dci.2009.04.004","article-title":"NOD-like subfamily of the nucleotide-binding domain and leucine-rich repeat containing family receptors and their expression in channel catfish","volume":"33","author":"Sha","year":"2009","journal-title":"Dev Comp Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib33","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.fsi.2010.09.014","article-title":"Cloning of two rainbow trout nucleotide-binding oligomerisation domain containing 2 (NOD2) splice variants and functional characterization of the NOD2 effectors domains","volume":"30","author":"Chang","year":"2011","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib34","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.fsi.2011.05.007","article-title":"Molecular characterization, expression and functional analysis of a nuclear oligomerization domain proteins subfamily C (NLRC) in Japanese flounder (Paralichthys olivaceus)","volume":"31","author":"Unajak","year":"2011","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib35","first-page":"291","article-title":"Isolation and preliminary identification of the causative agent of carp erythrodermatitis","volume":"47","author":"Bootsma","year":"1977","journal-title":"Vet Arh"},{"key":"10.1016\/j.fsi.2012.02.018_bib36","series-title":"Dropsy of mixed etiology in Catla catla (Ham.)","author":"Kumar","year":"1986"},{"key":"10.1016\/j.fsi.2012.02.018_bib37","first-page":"1044","article-title":"Aeromonas hydrophila septicemia of Indian major carps in some commercial fish farms of West Godavari District, Andhra Pradesh","volume":"58","author":"Karunasagar","year":"1989","journal-title":"Curr Sci"},{"issue":"8","key":"10.1016\/j.fsi.2012.02.018_bib38","first-page":"744","article-title":"Etiological charac-terization of acute infectious abdominal dropsy outbreak affecting Indian major carp, Cirrhinus mrigala in South Andaman","volume":"70","author":"Shome","year":"1996","journal-title":"Curr Sci"},{"key":"10.1016\/j.fsi.2012.02.018_bib39","doi-asserted-by":"crossref","first-page":"403e10","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J\u00a0Mol Biol"},{"key":"10.1016\/j.fsi.2012.02.018_bib40","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1093\/nar\/22.22.4673","article-title":"improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice","volume":"22","author":"Thompson","year":"1994","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.fsi.2012.02.018_bib41","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1093\/molbev\/msm092","article-title":"MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0","volume":"24","author":"Tamura","year":"2007","journal-title":"Mol Biol Evol"},{"key":"10.1016\/j.fsi.2012.02.018_bib42","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/1471-2164-8-124","article-title":"Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors","volume":"8","author":"Matsushima","year":"2007","journal-title":"BMC Genomics"},{"key":"10.1016\/j.fsi.2012.02.018_bib43","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/nar\/gkp985","article-title":"The Pfam protein families database","volume":"38","author":"Finn","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.fsi.2012.02.018_bib44","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1471-2105-4-29","article-title":"MatGAT: an application that generates similarity\/identity matrices using protein or DNA sequences","volume":"4","author":"Campanella","year":"2003","journal-title":"BMC Bioinform"},{"key":"10.1016\/j.fsi.2012.02.018_bib45","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C (T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2012.02.018_bib46","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.coi.2010.01.006","article-title":"Host-microb interactions in the developing zebrafish","volume":"22","author":"Kanther","year":"2010","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib47","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.fsi.2005.07.008","article-title":"Carp (Cyprinus carpio L.) innate immune factors are present before hatching","volume":"20","author":"Huttenhuis","year":"2006","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib48","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.fsi.2011.02.014","article-title":"Ontogeny and tissue\u2013specific expression of innate immune related genes in rohu, Labeo rohita (Hamilton)","volume":"30","author":"Nayak","year":"2011","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib49","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.dci.2011.06.018","article-title":"Molecular characterization of nucleotide binding and oligomerization domain (NOD)-2, analysis of its inductive expression and down-stream signaling following ligands exposure and bacterial infection in rohu (Labeo rohita)","volume":"36","author":"Swain","year":"2012","journal-title":"Dev Comp Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dci.2009.08.002","article-title":"Structure and expression pattern of teleost caspase recruitment domain (CARD) containing protein that are potentially involved in NF-\u03baB signaling","volume":"34","author":"Chang","year":"2010","journal-title":"Dev Comp Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib51","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1292\/jvms.68.471","article-title":"Up-regulation of NOD1 and NOD2 through TLR4 and TNF-\u03b1 in LPS-treated murine macrophages","volume":"68","author":"Takahashi","year":"2006","journal-title":"J\u00a0Vet Med Sci"},{"key":"10.1016\/j.fsi.2012.02.018_bib52","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.micinf.2007.01.014","article-title":"Role of nods in bacterial infection","volume":"9","author":"Bourhis","year":"2007","journal-title":"Microbes Infect"},{"key":"10.1016\/j.fsi.2012.02.018_bib53","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cellimm.2005.09.006","article-title":"Induction and localization of NOD2 protein in human endothelial cells","volume":"237","author":"Oh","year":"2005","journal-title":"Cell Immunol"},{"key":"10.1016\/j.fsi.2012.02.018_bib54","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/j.1365-2567.2007.02763.x","article-title":"Regulation and functional impact of lipopolysaccharide induced Nod2 gene expression in the murine\u00a0epididymal epithelial cell line PC1","volume":"124","author":"Muhlbauer","year":"2008","journal-title":"Immunology"},{"key":"10.1016\/j.fsi.2012.02.018_bib55","doi-asserted-by":"crossref","first-page":"32962","DOI":"10.1074\/jbc.M304355200","article-title":"Interferon-gamma augments CARD4\/NOD1 gene and protein expression through interferon regulatory factor-1 in intestinal epithelial cells","volume":"278","author":"Hisamatsu","year":"2003","journal-title":"J\u00a0Biol Chem"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464812000708?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464812000708?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T05:58:05Z","timestamp":1640843885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464812000708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5]]},"references-count":55,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["S1050464812000708"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2012.02.018","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2012,5]]}}}