{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T14:35:52Z","timestamp":1777991752844,"version":"3.51.4"},"reference-count":51,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.fsi.2013.08.029","type":"journal-article","created":{"date-parts":[[2013,9,12]],"date-time":"2013-09-12T15:00:18Z","timestamp":1378998018000},"page":"1779-1787","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Excretory products of the cestode, Schistocephalus solidus, modulate in\u00a0vitro responses of leukocytes from its specific host, the three-spined stickleback (Gasterosteus aculeatus)"],"prefix":"10.1016","volume":"35","author":[{"given":"J\u00f6rn Peter","family":"Scharsack","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anabel","family":"Gossens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederik","family":"Franke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Kurtz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2013.08.029_bib1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0304-4017(99)00039-4","article-title":"Parasites in cultured and feral fish","volume":"84","author":"Scholz","year":"1999","journal-title":"Vet Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1079\/JOH2006346","article-title":"How parasitism and pollution affect the physiological homeostasis of aquatic hosts","volume":"80","author":"Sures","year":"2006","journal-title":"J\u00a0Helminthol"},{"key":"10.1016\/j.fsi.2013.08.029_bib3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1017\/S0031182000052483","article-title":"Ultrastructural studies on the cellular response of fish hosts following experimental infection with the plerocercoid of Ligula intestinalis (Cestoda: Pseudophyllidae)","volume":"87","author":"Hoole","year":"1983","journal-title":"Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib4","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1017\/S0031182000067792","article-title":"Ligula intestinalis (L.) (Cestoda: Pseudophyllidea): polarization of cyprinid leucocytes as an indicator of host- and parasite-derived chemoattractants","volume":"107","author":"Taylor","year":"1993","journal-title":"Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib5","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S1050-4648(05)80013-0","article-title":"The chemiluminescence of cyprinid leucocytes in response to zymosan and extracts of Ligula intestinalis (Cestoda)","volume":"5","author":"Taylor","year":"1995","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2013.08.029_bib6","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1017\/S0022149X00700988","article-title":"Effects of Bothriocephalus acheilognathi on the polarization response of pronephric leucocytes of carp, Cyprinus carpio","volume":"74","author":"Nie","year":"2000","journal-title":"J\u00a0Helminthol"},{"key":"10.1016\/j.fsi.2013.08.029_bib7","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1017\/S0031182000060911","article-title":"Sequential development of the immune response in rainbow trout [Oncorhynchus mykiss (Walbaum, 1792)] to experimental plerocercoid infections of Diphyllobothrium dendriticum (Nitzsch, 1824)","volume":"104","author":"Sharp","year":"1992","journal-title":"Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib8","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1365-2761.1990.tb00784.x","article-title":"Protection of rainbow trout (Salmo gaidneri) against Diplostomum spathaceum (Digenea): the role of specific antibody and activated macrophages","volume":"13","author":"Whyte","year":"1990","journal-title":"J\u00a0Fish Dis"},{"key":"10.1016\/j.fsi.2013.08.029_bib9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0959-8030(92)90056-4","article-title":"The role of phagocytes in the protective mechanisms of fish","volume":"2","author":"Secombes","year":"1992","journal-title":"Ann Rev Fish Dis"},{"key":"10.1016\/j.fsi.2013.08.029_bib10","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0959-8030(96)90012-5","article-title":"Fish immune responses to experimental and natural infection with helminth parasites","volume":"6","author":"Secombes","year":"1996","journal-title":"Ann Rev Fish Dis"},{"key":"10.1016\/j.fsi.2013.08.029_bib11","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3354\/dao059141","article-title":"Modulation of granulocyte responses in three-spined sticklebacks Gasterosteus aculeatus infected with the tapeworm Schistocephalus solidus","volume":"59","author":"Scharsack","year":"2004","journal-title":"Dis Aquat Org"},{"key":"10.1016\/j.fsi.2013.08.029_bib12","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1095-8649.1989.tb02986.x","article-title":"Cytotoxic reactions of rainbow trout, Salmo gaidneri Richardson, macrophages for larvae of the eye fluke Diplostomum spathaceum (Digenea)","volume":"35","author":"Whyte","year":"1989","journal-title":"J\u00a0Fish Biol"},{"key":"10.1016\/j.fsi.2013.08.029_bib13","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/j.1365-2761.2012.01385.x","article-title":"Fish immune responses against endoparasitic nematodes \u2013 experimental models","volume":"35","author":"Buchman","year":"2012","journal-title":"J\u00a0Fish Dis"},{"key":"10.1016\/j.fsi.2013.08.029_bib14","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.molimm.2007.05.005","article-title":"Molecular cloning and expression analysis of T-bet in ginbuna crucian carp (Carassius auratus langsdorfii)","volume":"45","author":"Takizawa","year":"2008","journal-title":"Mol Immunol"},{"key":"10.1016\/j.fsi.2013.08.029_bib15","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/j.dci.2008.01.004","article-title":"GATA3 mRNA in ginbuna crucian carp (Carassius auratus langsdorfii): cDNA cloning, splice variants and expression analysis","volume":"32","author":"Takizawa","year":"2008","journal-title":"Dev Comp Immunol"},{"key":"10.1016\/j.fsi.2013.08.029_bib16","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1017\/S0031182009991466","article-title":"The three-spined stickleback-Schistocephalus solidus system: an experimental model for investigating host\u2013parasite interactions in fish","volume":"137","author":"Barber","year":"2010","journal-title":"Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib17","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1530\/rep.1.00742","article-title":"The tapeworm Ligula intestinalis (Cestoda: Pseudophyllidea) inhibits LH expression and puberty in its teleost host, Rutilus rutilus","volume":"130","author":"Carter","year":"2005","journal-title":"Reproduction"},{"key":"10.1016\/j.fsi.2013.08.029_bib18","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1365-2761.1982.tb00466.x","article-title":"Ultrastructural studies on the cellular response of roach, Rutilus rutilus L., to the plerocercoid larva of the pseudophyllidean cestode, Ligula intestinalis","volume":"5","author":"Hoole","year":"1982","journal-title":"J\u00a0Fish Dis"},{"key":"10.1016\/j.fsi.2013.08.029_bib19","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.fsi.2008.03.018","article-title":"Living of a fish: a trade-off between parasites and the immune system","volume":"25","author":"Sitja-Bobadilla","year":"2008","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2013.08.029_bib20","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1134\/S1062359011060069","article-title":"Composition of leucocytes of the head kidney of the crucian carp (Carassius auratus gibelio, Cypriniformes: Cyprinidae) as affected by invasion of cestode Digramma interrupta (Cestoda; Pseudophyllidea)","volume":"38","author":"Kutyrev","year":"2011","journal-title":"Biol Bullet"},{"key":"10.1016\/j.fsi.2013.08.029_bib21","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1017\/S0031182000071687","article-title":"Host specificity in Schistocephalus solidus","volume":"56","author":"Braten","year":"1966","journal-title":"Parasitology"},{"key":"10.1016\/j.fsi.2013.08.029_bib22","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF00310212","article-title":"Parasites determine a predators optimal feeding strategy","volume":"15","author":"Milinski","year":"1984","journal-title":"Behav Ecol Sociobiol"},{"key":"10.1016\/j.fsi.2013.08.029_bib23","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1163\/156853986X00883","article-title":"Risk of predation of parasitized sticklebacks (Gasterosteus aculeatus) under competition for food","volume":"93","author":"Milinski","year":"1985","journal-title":"Behav"},{"key":"10.1016\/j.fsi.2013.08.029_bib24","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1139\/z88-350","article-title":"Risk taking in parasitized sticklebacks under threat of predation: effects of energetic need and food availability","volume":"66","author":"Godin","year":"1988","journal-title":"Canad J Zool"},{"key":"10.1016\/j.fsi.2013.08.029_bib25","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1163\/156853995X00540","article-title":"The effect of Schistocephalus solidus (Cestoda: Pseudophyllidea) on the foraging and shoaling behaviour of three-spined sticklebacks, Gasterosteus aculeatus","volume":"132","author":"Barber","year":"1995","journal-title":"Behav"},{"key":"10.1016\/j.fsi.2013.08.029_bib26","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1017\/S0031182000031206","article-title":"Host specificity and rejection of Schistocephalus solidus","volume":"59","author":"Orr","year":"1969","journal-title":"Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib27","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.exppara.2006.12.013","article-title":"Schistocephalus solidus: establishment of tapeworms in sticklebacks \u2013 fast food or fast lane?","volume":"116","author":"Hammerschmidt","year":"2007","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib28","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1016\/j.ijpara.2005.08.011","article-title":"Surface carbohydrate composition of a tapeworm in its consecutive intermediate hosts: individual variation and fitness consequences","volume":"35","author":"Hammerschmidt","year":"2005","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib29","first-page":"3151","article-title":"Who is in control of the stickleback immune system: interactions between Schistocephalus solidus and its specific vertebrate host","volume":"274","author":"Scharsack","year":"2007","journal-title":"Proc R Soc Lond B"},{"key":"10.1016\/j.fsi.2013.08.029_bib30","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1645\/GE-225R","article-title":"The clearance of hidden cestode infection triggered by an independent activation of host defense in a teleost fish","volume":"90","author":"Wedekind","year":"2004","journal-title":"J\u00a0Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib31","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/j.0014-3820.2006.tb01141.x","article-title":"Multiple infections: relatedness and time between infections affect the establishment and growth of the cestode Schistocephalus solidus in its stickleback host","volume":"60","author":"J\u00e4ger","year":"2006","journal-title":"Evol"},{"key":"10.1016\/j.fsi.2013.08.029_bib32","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1098\/rspb.2003.2567","article-title":"Major histocompatibility complex diversity influences parasite resistance and innate immunity in sticklebacks","volume":"271","author":"Kurtz","year":"2004","journal-title":"Proc R Soc Lond B"},{"key":"10.1016\/j.fsi.2013.08.029_bib33","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s10682-005-0883-6","article-title":"Geographical and temporal FA variation in threespine stickleback populations from Galicia (NW Spain)","volume":"19","author":"Prieto","year":"2005","journal-title":"Evol Ecol"},{"key":"10.1016\/j.fsi.2013.08.029_bib34","first-page":"1030","article-title":"Simultaneous hermaphrodites reproducing in pairs self-fertilize some of their eggs: an experimental test of predictions of mixed-mating and Hermaphrodite's Dilemma theory","volume":"16","author":"L\u00fcscher","year":"2003","journal-title":"J\u00a0Evol Biol"},{"key":"10.1016\/j.fsi.2013.08.029_bib35","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1017\/S0031182097001406","article-title":"The infectivity, growth, and virulence of the cestode Schistocephalus solidus in its first intermediate host, the copepod Macrocyclops albidus","volume":"115","author":"Wedekind","year":"1997","journal-title":"Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib36","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.2307\/3283228","article-title":"Infectivity of plerocercoids of Schistocephalus solidus (Cestoda, Ligulidae) and fecundity of the adults in an experimental definitive host, Gallus gallus","volume":"78","author":"Tierney","year":"1992","journal-title":"J\u00a0Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib37","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/cyto.990160209","article-title":"Rapid quantification of lymphocyte subsets in heterogeneous cell populations by flow-cytometry","volume":"16","author":"Pechhold","year":"1994","journal-title":"Cytom"},{"key":"10.1016\/j.fsi.2013.08.029_bib38","doi-asserted-by":"crossref","first-page":"203","DOI":"10.3354\/dao041203","article-title":"Flow cytometric analysis of proliferative responses of carp (Cyprinus carpio L.) peripheral blood leukocytes to mitogens and to the hemoflagellate Trypanoplasma borreli","volume":"41","author":"Scharsack","year":"2000","journal-title":"Dis Aquat Org"},{"key":"10.1016\/j.fsi.2013.08.029_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molbiopara.2009.04.008","article-title":"Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity","volume":"167","author":"Hewitson","year":"2009","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib40","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.fsi.2004.09.006","article-title":"Innate immunity of fish (overview)","volume":"20","author":"Magnadottir","year":"2006","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2013.08.029_bib41","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/S0020-7519(97)00067-2","article-title":"Effect of Fasciola hepatica excretory\u2013secretory products on the metabolic burst of sheep and human neutrophils","volume":"27","author":"Jefferies","year":"1997","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib42","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1006\/expr.2000.4495","article-title":"Fasciola hepatica: heterologous expression and functional characterization of a thioredoxin peroxidase","volume":"95","author":"Salzar-Calderon","year":"2000","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib43","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.molbiopara.2008.05.002","article-title":"Excretory\u2013secretory products of larval Fasciola hepatica investigated using a two-dimensional proteomic approach","volume":"161","author":"Gourbal","year":"2008","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib44","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1098\/rspb.2001.1668","article-title":"Effects of Schistocephalus solidus infection on brain monoaminergic activity in female three-spined sticklebacks Gasterosteus aculeatus","volume":"268","author":"Overli","year":"2001","journal-title":"Proc R Soc Lond B"},{"key":"10.1016\/j.fsi.2013.08.029_bib45","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.fsi.2010.08.016","article-title":"T\u00a0cell diversity and TcR repertoires in teleost fish","volume":"31","author":"Castro","year":"2011","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/j.fsi.2013.08.029_bib46","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.dci.2011.01.013","article-title":"Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish","volume":"35","author":"Toda","year":"2011","journal-title":"Dev Comp Immunol"},{"key":"10.1016\/j.fsi.2013.08.029_bib47","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0020-7519(94)00076-Z","article-title":"Immunolabelling of fish host molecules on the tegumental surface of Ligula intestinalis (Cestoda: Ppseudophyllidea)","volume":"25","author":"Williams","year":"1995","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib48","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/0020-7519(85)90005-0","article-title":"The in\u00a0vitro culture and tegumental dynamics of the plerocercoid of Ligula intestinalis (Cestoda: Pseudophyllidea)","volume":"15","author":"Hoole","year":"1985","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.fsi.2013.08.029_bib49","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1046\/j.1365-2540.1998.00435.x","article-title":"Local adaptation in host\u2013parasite systems","volume":"81","author":"Kaltz","year":"1998","journal-title":"Hered"},{"key":"10.1016\/j.fsi.2013.08.029_bib50","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1007\/s00436-011-2326-3","article-title":"Host\u2013parasite interactions in sympatric and allopatric populations of European bitterling","volume":"109","author":"Francova","year":"2011","journal-title":"Parasitol Res"},{"key":"10.1016\/j.fsi.2013.08.029_bib51","first-page":"1523","article-title":"Habitat specific adaptation of immune responses of stickleback (Gasterosteus aculeatus) lake and river ecotypes","volume":"274","author":"Scharsack","year":"2007","journal-title":"Proc R Soc Lond B"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464813007432?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464813007432?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T05:07:23Z","timestamp":1760936843000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464813007432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":51,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S1050464813007432"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2013.08.029","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Excretory products of the cestode, Schistocephalus solidus, modulate in\u00a0vitro responses of leukocytes from its specific host, the three-spined stickleback (Gasterosteus aculeatus)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2013.08.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}