{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T09:53:07Z","timestamp":1785577987278,"version":"3.56.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"crossref","award":["KSCX2-YW-N-101"],"award-info":[{"award-number":["KSCX2-YW-N-101"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"crossref","award":["KSCX2-1W\u2013N-004"],"award-info":[{"award-number":["KSCX2-1W\u2013N-004"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30970341"],"award-info":[{"award-number":["30970341"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31172070"],"award-info":[{"award-number":["31172070"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.fsi.2015.06.023","type":"journal-article","created":{"date-parts":[[2015,6,22]],"date-time":"2015-06-22T17:53:28Z","timestamp":1434995608000},"page":"334-345","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":75,"title":["Transcriptome-wide identification, molecular evolution and expression analysis of Toll-like receptor family in a Tibet fish, Gymnocypris przewalskii"],"prefix":"10.1016","volume":"46","author":[{"given":"Chao","family":"Tong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqiu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cunfang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianquan","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfang","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2015.06.023_bib1","series-title":"The Qinghai-Tibetan Plateau Fish","author":"Wu","year":"1991"},{"key":"10.1016\/j.fsi.2015.06.023_bib2","first-page":"244","article-title":"Uplift of the Tibetan Plateau influenced the morphological evolution of animals","volume":"6","author":"Wen","year":"2014","journal-title":"J.\u00a0Agric. Sci."},{"key":"10.1016\/j.fsi.2015.06.023_bib3","series-title":"Study of Fish Fauna in Qinghai Lake","author":"Zhu","year":"1975"},{"key":"10.1016\/j.fsi.2015.06.023_bib4","series-title":"The Protection Research of Gymnocypris Przewalskii","author":"Chen","year":"2011"},{"key":"10.1016\/j.fsi.2015.06.023_bib5","first-page":"80","article-title":"An overview on the resource enhancement of Gymnocypris przewalskii (Kessler)","volume":"27","author":"Shi","year":"2009","journal-title":"Chin. Fish. Econ."},{"key":"10.1016\/j.fsi.2015.06.023_bib6","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/35100529","article-title":"Toll-like receptors and innate immunity","volume":"1","author":"Medzhitov","year":"2001","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib7","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/ni.1863","article-title":"The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors","volume":"11","author":"Kawai","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib8","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.4049\/jimmunol.179.2.1129","article-title":"Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii","volume":"179","author":"Debierre-Grockiego","year":"2007","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib9","doi-asserted-by":"crossref","first-page":"416","DOI":"10.4049\/jimmunol.167.1.416","article-title":"Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite","volume":"167","author":"Campos","year":"2001","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib10","doi-asserted-by":"crossref","first-page":"3515","DOI":"10.4049\/jimmunol.177.6.3515","article-title":"Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection","volume":"177","author":"Bafica","year":"2006","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib11","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1126\/science.1109893","article-title":"TLR11 activation of dendritic cells by a protozoan profilin-like protein","volume":"308","author":"Yarovinsky","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.fsi.2015.06.023_bib12","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.dci.2011.03.006","article-title":"Toll-like receptors in bony fish: from genomics to function","volume":"35","author":"Palti","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib13","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.fsi.2011.11.021","article-title":"Molecular cloning of orange-spotted grouper (Epinephelus coioides) TLR21 and expression analysis post Cryptocaryon irritans infection","volume":"32","author":"Li","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib14","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1016\/j.fsi.2011.04.012","article-title":"Orange-spotted grouper (Epinephelus coioides) TLR2, MyD88 and IL-1\u03b2 involved in anti-Cryptocaryon irritans response","volume":"30","author":"Li","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib15","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.fsi.2013.05.023","article-title":"Expression profiles of toll-like receptors in channel catfish (Ictalurus punctatus) after infection with Ichthyophthirius multifiliis","volume":"35","author":"Zhao","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib16","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.fsi.2010.09.007","article-title":"Transcriptome analysis of rainbow trout infected with high and low virulence strains of infectious hematopoietic necrosis virus","volume":"30","author":"Purcell","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib17","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.fsi.2014.10.040","article-title":"Transcriptome analysis of medaka following epinecidin-1 and TH1-5 treatment of NNV infection","volume":"42","author":"Wang","year":"2015","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2015.06.023_bib18","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.fsi.2014.11.018","article-title":"Transcriptome analysis revealed changes of multiple genes involved in immunity in Cynoglossus semilaevis during Vibrio anguillarum infection","volume":"43","author":"Zhang","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib19","doi-asserted-by":"crossref","first-page":"9780","DOI":"10.1038\/srep09780","article-title":"Local adaptation and ecological speciation of Gymnocypris przewalskii (Cyprinidae) on the Tibetan Plateau","volume":"5","author":"Zhang","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fsi.2015.06.023_bib20","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"Tamura","year":"2011","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.fsi.2015.06.023_bib21","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1093\/molbev\/msm088","article-title":"PAML 4: phylogenetic analysis by maximum likelihood","volume":"24","author":"Yang","year":"2007","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.fsi.2015.06.023_bib22","series-title":"The PyMOL Molecular Graphics System","author":"DeLano","year":"2002"},{"key":"10.1016\/j.fsi.2015.06.023_bib23","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1093\/bioinformatics\/btp612","article-title":"DEGseq: an R package for identifying differentially expressed genes from RNA-seq data","volume":"26","author":"Wang","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.fsi.2015.06.023_bib24","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.ygcen.2009.02.005","article-title":"Growth hormone and insulin-like growth factor of naked carp (Gymnocypris przewalskii) in Lake Qinghai: expression in different water environments","volume":"161","author":"Cao","year":"2009","journal-title":"General Comp. Endocrinol."},{"key":"10.1016\/j.fsi.2015.06.023_bib25","first-page":"38","article-title":"Expression and cloning of two glyceraldehyde 3-phosphate dehydrogenase mRNAs from Gymnocypris przewalskii in Qinghai Lake","volume":"21","author":"Wei","year":"2013","journal-title":"Acta Lab. Anim. Sci. Sin."},{"key":"10.1016\/j.fsi.2015.06.023_bib26","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using Real-Time quantitative PCR and the 2 \u2212 \u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2015.06.023_bib27","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1365-2052.2011.02178.x","article-title":"Mapping of the Toll-like receptor family in channel catfish, Ictalurus punctatus","volume":"42","author":"Quiniou","year":"2011","journal-title":"Anim. Genet."},{"key":"10.1016\/j.fsi.2015.06.023_bib28","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.molimm.2003.10.001","article-title":"Toll-like receptor gene family and TIR-domain adapters in Danio rerio","volume":"40","author":"Jault","year":"2004","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib29","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s10126-010-9268-0","article-title":"Construction and characterization of two bacterial artificial chromosome libraries of grass carp","volume":"12","author":"Jang","year":"2010","journal-title":"Mar. Biotechnol."},{"key":"10.1016\/j.fsi.2015.06.023_bib30","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.fsi.2014.09.022","article-title":"Toll-like receptor recognition of bacteria in fish: Ligand specificity and signal pathways","volume":"41","author":"Zhang","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib31","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.4049\/jimmunol.0801755","article-title":"Evolution of lipopolysaccharide (LPS) recognition and signaling: fish TLR4 does not recognize LPS and negatively regulates NF-\u03baB activation","volume":"182","author":"Sepulcre","year":"2009","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib32","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.fsi.2014.10.006","article-title":"Identification and characterisation of TLR18-21 genes in Atlantic salmon (Salmo salar)","volume":"41","author":"Lee","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib33","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/j.fsi.2012.02.024","article-title":"Cloning and characterization of the grass carp (Ctenopharyngodon idella) Toll-like receptor 22 gene, a fish-specific gene","volume":"32","author":"Lv","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib34","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.fsi.2010.04.013","article-title":"SNP discovery and development of genetic markers for mapping innate immune response genes in common carp (Cyprinus carpio)","volume":"29","author":"Kongchum","year":"2010","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib35","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00251-013-0751-4","article-title":"Identification and functional characterization of nonmammalian Toll-like receptor 20","volume":"66","author":"Pietretti","year":"2014","journal-title":"Immunogenetics"},{"key":"10.1016\/j.fsi.2015.06.023_bib36","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.fsi.2013.07.027","article-title":"Molecular characterization and expression analysis of Toll-like receptor 21 cDNA from Paralichthys olivaceus","volume":"35","author":"Gao","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib37","first-page":"27","article-title":"Duplicated Gene Evolution Following Whole-genome Duplication in Teleost Fish","author":"Guo","year":"2011"},{"key":"10.1016\/j.fsi.2015.06.023_bib38","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.molimm.2003.10.003","article-title":"Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish","volume":"40","author":"Meijer","year":"2004","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib39","doi-asserted-by":"crossref","first-page":"e71331","DOI":"10.1371\/journal.pone.0071331","article-title":"Ongoing speciation in the Tibetan Plateau Gymnocypris species complex","volume":"8","author":"Ry","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.fsi.2015.06.023_bib40","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.dci.2006.08.007","article-title":"Characterization of twin toll-like receptors from rainbow trout (Oncorhynchus mykiss): evolutionary relationship and induced expression by Aeromonas salmonicida salmonicida","volume":"31","author":"Rebl","year":"2007","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib41","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00251-013-0694-9","article-title":"Comprehensive survey and genomic characterization of Toll-like receptors (TLRs) in channel catfish, Ictalurus punctatus: identification of novel fish TLRs","volume":"65","author":"Quiniou","year":"2013","journal-title":"Immunogenetics"},{"key":"10.1016\/j.fsi.2015.06.023_bib42","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1186\/1471-2148-11-368","article-title":"Signatures of positive selection in Toll-like receptor (TLR) genes in mammals","volume":"11","author":"Areal","year":"2011","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.fsi.2015.06.023_bib43","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/gbe\/evu266","article-title":"Constraint and adaptation in newt Toll-like receptor genes","volume":"7","author":"Babik","year":"2015","journal-title":"Genome Biol. Evol."},{"key":"10.1016\/j.fsi.2015.06.023_bib44","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.fsi.2013.04.043","article-title":"Evolutionary analysis of TLR9 genes reveals the positive selection of extant teleosts in Perciformes","volume":"35","author":"Zhu","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib45","doi-asserted-by":"crossref","first-page":"8965","DOI":"10.1007\/s11033-012-1765-y","article-title":"Positive selection pressure within teleost toll-like receptors tlr21 and tlr22 subfamilies and their response to temperature stress and microbial components in zebrafish","volume":"39","author":"Sundaram","year":"2012","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.fsi.2015.06.023_bib46","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/1471-2164-8-124","article-title":"Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors","volume":"8","author":"Matsushima","year":"2007","journal-title":"BMC Genomics"},{"key":"10.1016\/j.fsi.2015.06.023_bib47","doi-asserted-by":"crossref","first-page":"305","DOI":"10.2174\/1567269054087613","article-title":"Leucine-rich repeats (LRRs): structure, function, evolution and interaction with ligands","volume":"2","author":"Matsushima","year":"2005","journal-title":"Drug Des. Rev. Online"},{"key":"10.1016\/j.fsi.2015.06.023_bib48","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.molimm.2003.10.001","article-title":"Toll-like receptor gene family and TIR-domain adapters in Danio rerio","volume":"40","author":"Jault","year":"2004","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib49","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/35099560","article-title":"Recognition of double-stranded RNA and activation of NF-\u03baB by Toll-like receptor 3","volume":"413","author":"Alexopoulou","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.fsi.2015.06.023_bib50","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1126\/science.1093620","article-title":"Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8","volume":"303","author":"Heil","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.fsi.2015.06.023_bib51","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.exppara.2011.03.010","article-title":"Proinflammatory responses by glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum are mainly mediated through the recognition of TLR2\/TLR1","volume":"128","author":"Zhu","year":"2011","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.fsi.2015.06.023_bib52","doi-asserted-by":"crossref","first-page":"8606","DOI":"10.1074\/jbc.M413541200","article-title":"Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity","volume":"280","author":"Krishnegowda","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2015.06.023_bib53","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1111\/j.1550-7408.2001.tb00322.x","article-title":"The I-antigens of Ichthyophthirius multifiliis are GPI-Anchored Proteins","volume":"48","author":"Clark","year":"2001","journal-title":"J.\u00a0Eukaryot. Microbiol."},{"key":"10.1016\/j.fsi.2015.06.023_bib54","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.4049\/jimmunol.173.4.2552","article-title":"Transcriptional regulation of the human TLR9 gene","volume":"173","author":"Takeshita","year":"2004","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib55","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.4049\/jimmunol.182.3.1386","article-title":"TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions","volume":"182","author":"Fakher","year":"2009","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib56","doi-asserted-by":"crossref","first-page":"5688","DOI":"10.4049\/jimmunol.173.9.5688","article-title":"Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T.\u00a0cruzi","volume":"173","author":"Oliveira","year":"2004","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib57","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1186\/1471-2148-12-256","article-title":"Diversification of the expanded teleost-specific toll-like receptor family in Atlantic cod, Gadus morhua","volume":"12","author":"Sundaram","year":"2012","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.fsi.2015.06.023_bib58","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.fsi.2007.11.005","article-title":"Evidence for positive selection in the TLR9 gene of teleosts","volume":"24","author":"Chen","year":"2008","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.023_bib59","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.it.2008.12.001","article-title":"Variation matters: TLR structure and species-specific pathogen recognition","volume":"30","author":"Werling","year":"2009","journal-title":"Trends Immunol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464815300516?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464815300516?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T11:14:52Z","timestamp":1566904492000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464815300516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":59,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S1050464815300516"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2015.06.023","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptome-wide identification, molecular evolution and expression analysis of Toll-like receptor family in a Tibet fish, Gymnocypris przewalskii","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2015.06.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}