{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:04:30Z","timestamp":1777982670869,"version":"3.51.4"},"reference-count":60,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Guangxi Science and technology Research Program","award":["14121004-1-1"],"award-info":[{"award-number":["14121004-1-1"]}]},{"name":"Tilapia Industrial Technology system of China","award":["CARS-49"],"award-info":[{"award-number":["CARS-49"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.fsi.2015.06.027","type":"journal-article","created":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T21:53:56Z","timestamp":1435182836000},"page":"346-353","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":80,"title":["Trancriptomic profiling revealed the signatures of acute immune response in tilapia (Oreochromis niloticus) following Streptococcus iniae challenge"],"prefix":"10.1016","volume":"46","author":[{"given":"Jiajie","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuwei","family":"Ao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongju","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yafen","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganqiu","family":"Lan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hesheng","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Gan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2015.06.027_bib1","series-title":"The Genetic Improvement of Farmed Tilapias (GIFT) Project: the Story 80 Far","author":"Pullin","year":"1991"},{"key":"10.1016\/j.fsi.2015.06.027_bib2","first-page":"445","article-title":"Tilapia Bacterial Diseases","author":"Plumb","year":"1999"},{"key":"10.1016\/j.fsi.2015.06.027_bib3","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0044-8486(00)00346-X","article-title":"Density and dose: factors affecting mortality of Streptococcusiniae infected tilapia (Oreochromisniloticus)","volume":"188","author":"Shoemaker","year":"2000","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2015.06.027_bib4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.gene.2015.04.025","article-title":"\u03b2-Defensin in Nile tilapia (Oreochromis niloticus): sequence, tissue expression, and anti-bacterial activity of synthetic peptides","volume":"566","author":"Dong","year":"2015","journal-title":"Gene"},{"key":"10.1016\/j.fsi.2015.06.027_bib5","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.fsi.2012.11.048","article-title":"Major histocompatibility complex class IIA and IIB genes of Nile tilapia Oreochromis niloticus: genomic structure, molecular polymorphism and expression patterns","volume":"34","author":"Pang","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib6","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.dci.2015.03.008","article-title":"Cloning and primary immunological study of TGF-\u03b21 and its receptors T\u03b2R I\/T\u03b2R II in tilapia (Oreochromis niloticus)","volume":"51","author":"Zhan","year":"2015","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib7","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.fsi.2015.01.035","article-title":"Molecular and functional characterization of CD59 from Nile tilapia (Oreochromis niloticus) involved in the immune response to Streptococcus agalactiae","volume":"44","author":"Gan","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib8","first-page":"1","article-title":"Molecular characterization and expression of Lck in Nile tilapia (Oreochromis niloticus) in response to Streptococcus agalactiae stimulus","author":"Gan","year":"2014","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.fsi.2015.06.027_bib9","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.gene.2014.07.032","article-title":"Molecular characterization and expression of CD2BP2 in Nile tilapia (Oreochromis niloticus) in response to Streptococcus agalactiae stimulus","volume":"548","author":"Gan","year":"2014","journal-title":"Gene"},{"key":"10.1016\/j.fsi.2015.06.027_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cellimm.2013.12.008","article-title":"Immunological enhancement action of endotoxin-free tilapia heat shock protein 70 against Streptococcus iniae","volume":"290","author":"Chen","year":"2014","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib11","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/jfb.12004","article-title":"Identification of multiple genes and their expression profiles in four strains of Oreochromis spp. in response to Streptococcus iniae","volume":"82","author":"Wang","year":"2013","journal-title":"J.\u00a0Fish Biol."},{"key":"10.1016\/j.fsi.2015.06.027_bib12","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.vetimm.2011.05.015","article-title":"Identification and expression profile of multiple genes in Nile tilapia in response to formalin killed Streptococcus iniae vaccination","volume":"142","author":"Pridgeon","year":"2011","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.fsi.2015.06.027_bib13","first-page":"e108","article-title":"Use of RNA-seq in aquaculture research","volume":"2","author":"Li","year":"2014","journal-title":"Poult. Fish. Wildl. Sci."},{"key":"10.1016\/j.fsi.2015.06.027_bib14","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.fsi.2012.02.004","article-title":"RNA-seq analysis of mucosal immune responses reveals signatures of intestinal barrier disruption and pathogen entry following Edwardsiella ictaluri infection in channel catfish, Ictalurus punctatus","volume":"32","author":"Li","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib15","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.molimm.2013.04.014","article-title":"Basal polarization of the mucosal compartment in Flavobacterium columnare susceptible and resistant channel catfish (Ictalurus punctatus)","volume":"56","author":"Peatman","year":"2013","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib16","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.1007\/s11033-013-2667-3","article-title":"Transcriptome profiling and digital gene expression analysis of Nile tilapia (Oreochromis niloticus) infected by Streptococcus agalactiae","volume":"40","author":"Zhang","year":"2013","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.fsi.2015.06.027_bib17","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/nbt.1883","article-title":"Full-length transcriptome assembly from RNA-Seq data without a reference genome","volume":"29","author":"Grabherr","year":"2011","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.fsi.2015.06.027_bib18","doi-asserted-by":"crossref","first-page":"3420","DOI":"10.1093\/nar\/gkn176","article-title":"High-throughput functional annotation and data mining with the Blast2GO suite","volume":"36","author":"Gotz","year":"2008","journal-title":"Nucleic Acid. Res."},{"key":"10.1016\/j.fsi.2015.06.027_bib19","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1091\/mbc.10.6.1859","article-title":"Dynamics of gene expression revealed by comparison of serial analysis of gene expression transcript profiles from yeast grown on two different carbon sources","volume":"10","author":"Kal","year":"1999","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.fsi.2015.06.027_bib20","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1186\/gb-2010-11-3-r25","article-title":"A\u00a0scaling normalization method for differential expression analysis of RNA-seq data","volume":"11","author":"Robinson","year":"2010","journal-title":"Genome Biol."},{"key":"10.1016\/j.fsi.2015.06.027_bib21","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1093\/bioinformatics\/btn250","article-title":"Ontologizer 2.0\u2013a multifunctional tool for GO term enrichment analysis and data exploration","volume":"24","author":"Bauer","year":"2008","journal-title":"Bioinformatics"},{"key":"10.1016\/j.fsi.2015.06.027_bib22","doi-asserted-by":"crossref","first-page":"3024","DOI":"10.1093\/bioinformatics\/btm440","article-title":"Improved detection of overrepresentation of Gene-Ontology annotations with parent child analysis","volume":"23","author":"Grossmann","year":"2007","journal-title":"Bioinformatics"},{"key":"10.1016\/j.fsi.2015.06.027_bib23","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.vetmic.2012.04.035","article-title":"PCR detection and PFGE genotype analyses of streptococcal clinical isolates from tilapia in China","volume":"159","author":"Chen","year":"2012","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.fsi.2015.06.027_bib24","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.fsi.2015.03.002","article-title":"Dietary Aloe vera supplementation on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT)","volume":"44","author":"Gabriel","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib25","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.dci.2013.12.014","article-title":"Nutritional impacts on gene expression in the surface mucosa of blue catfish (Ictalurus furcatus)","volume":"44","author":"Li","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib26","doi-asserted-by":"crossref","first-page":"e74581","DOI":"10.1371\/journal.pone.0074581","article-title":"Short-term feed deprivation alters immune status of surface mucosa in channel catfish (Ictalurus punctatus)","volume":"8","author":"Liu","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.fsi.2015.06.027_bib27","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1007\/s10126-012-9466-z","article-title":"Characterization of European sea bass transcripts by RNA SEQ after oral vaccine against V.\u00a0anguillarum","volume":"14","author":"Sarropoulou","year":"2012","journal-title":"Mar. Biotechnol."},{"key":"10.1016\/j.fsi.2015.06.027_bib28","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1093\/dnares\/dst022","article-title":"Analysis of stress-responsive transcriptome in the intestine of Asian seabass (Lates calcarifer) using RNA-Seq","volume":"20","author":"Xia","year":"2013","journal-title":"DNA Res."},{"key":"10.1016\/j.fsi.2015.06.027_bib29","doi-asserted-by":"crossref","first-page":"e63604","DOI":"10.1371\/journal.pone.0063604","article-title":"Characterization of gonadal transcriptomes from Nile tilapia (Oreochromis niloticus) reveals differentially expressed genes","volume":"8","author":"Tao","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.fsi.2015.06.027_bib30","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.fsi.2015.01.022","article-title":"Transcriptome analysis revealed positive selection of immune-related genes in tilapia","volume":"44","author":"Xiao","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib31","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.aquaculture.2014.06.009","article-title":"Deep sequencing of the tilapia (Oreochromis niloticus) liver transcriptome response to dietary protein to starch ratio","volume":"433","author":"Xiong","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2015.06.027_bib32","doi-asserted-by":"crossref","first-page":"64","DOI":"10.17485\/ijst\/2011\/v4is.52","article-title":"Transcriptome analysis of the molecular mechanisms for Tilapia sex determination, differentiation and sex reversal","volume":"4","author":"Wang","year":"2011","journal-title":"Ind. J. Sci. Technol."},{"key":"10.1016\/j.fsi.2015.06.027_bib33","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.dci.2012.05.006","article-title":"Transcriptomic signatures of attachment, NF-\u03baB suppression and IFN stimulation in the catfish gill following columnaris bacterial infection","volume":"38","author":"Sun","year":"2012","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib34","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.fsi.2012.08.018","article-title":"Putative roles for a rhamnose binding lectin in Flavobacterium columnare pathogenesis in channel catfish Ictalurus punctatus","volume":"33","author":"Beck","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib35","first-page":"2011","article-title":"Diversified carbohydrate-binding lectins from marine resources","author":"Ogawa","year":"2011","journal-title":"J.\u00a0Amino Acids"},{"key":"10.1016\/j.fsi.2015.06.027_bib36","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.dci.2007.08.007","article-title":"Isolation and characterization of l-rhamnose-binding lectin, which binds to microsporidian Glugea plecoglossi, from ayu (Plecoglossus altivelis) eggs","volume":"32","author":"Watanabe","year":"2008","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib37","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.dci.2014.01.018","article-title":"L-rhamnose-binding lectins (RBLs) in channel catfish, Ictalurus punctatus: characterization and expression profiling in mucosal tissues","volume":"44","author":"Thongda","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib38","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.fsi.2015.03.037","article-title":"Molecular characterization and functional analysis of a novel C-type lectin receptor-like gene from a teleost fish, Plecoglossus altivelis","volume":"44","author":"Yang","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib39","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.dci.2013.10.006","article-title":"Molecular cloning and expression analysis of mannose receptor C type 1 in grass carp (Ctenopharyngodon idella)","volume":"43","author":"Wang","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib40","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/ni.2378","article-title":"The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-kappa B","volume":"13","author":"Schneider","year":"2012","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib41","doi-asserted-by":"crossref","first-page":"e491","DOI":"10.1038\/cddis.2013.23","article-title":"OLA1 protects cells in heat shock by stabilizing HSP70","volume":"4","author":"Mao","year":"2013","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.fsi.2015.06.027_bib42","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.fsi.2013.01.002","article-title":"Early mucosal responses in blue catfish (Ictalurus furcatus) skin to Aeromonas hydrophila infection","volume":"34","author":"Li","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib43","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.dci.2012.11.009","article-title":"Evasion of mucosal defenses during Aeromonas hydrophila infection of channel catfish (Ictalurus punctatus) skin","volume":"39","author":"Li","year":"2013","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib44","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.fsi.2014.01.012","article-title":"Gene expression of pro-and anti-apoptotic proteins in rock bream (Oplegnathus fasciatus) infected with megalocytivirus (family Iridoviridae)","volume":"37","author":"Jung","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib45","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1182\/blood-2005-11-4616","article-title":"Gimap4 accelerates T-cell death","volume":"108","author":"Schnell","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.fsi.2015.06.027_bib46","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0962-8924(03)00037-0","article-title":"Bacterial virulence factors targeting Rho GTPases: parasitism or symbiosis?","volume":"13","author":"Boquet","year":"2003","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.fsi.2015.06.027_bib47","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nrmicro1150","article-title":"Bacterial cytotoxins: targeting eukaryotic switches","volume":"3","author":"Aktories","year":"2005","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.fsi.2015.06.027_bib48","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.fsi.2014.10.001","article-title":"Characterization of myeloid-specific peroxidase, keratin 8, and dual specificity phosphatase 1 as innate immune genes involved in the resistance of crucian carp (Carassius auratus gibelio) to Cyprinid herpesvirus 2 infection","volume":"41","author":"Podok","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib49","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/jmv.23873","article-title":"Keratin 8 is involved in hepatitis B virus replication","volume":"86","author":"Zhong","year":"2014","journal-title":"J.\u00a0Med. Virol."},{"key":"10.1016\/j.fsi.2015.06.027_bib50","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/nature10606","article-title":"Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum","volume":"480","author":"Crosnier","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.fsi.2015.06.027_bib51","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.clim.2004.07.014","article-title":"Targeting of the actin cytoskeleton during infection by Salmonella strains","volume":"114","author":"Guiney","year":"2005","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib52","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1365-2761.2012.01341.x","article-title":"Differential expression profiling of orange-spotted grouper larvae, Epinephelus coioides (Hamilton), that survived a betanodavirus outbreak","volume":"35","author":"Wu","year":"2012","journal-title":"J.\u00a0Fish Dis."},{"key":"10.1016\/j.fsi.2015.06.027_bib53","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02012-14","article-title":"RNase L interacts with Filamin A to regulate actin dynamics and barrier function for viral entry","volume":"5","author":"Malathi","year":"2014","journal-title":"mBio"},{"key":"10.1016\/j.fsi.2015.06.027_bib54","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ygcen.2015.01.004","article-title":"The CXC chemokine receptors of fish: insights into CXCR evolution in the vertebrates","volume":"215","author":"Zou","year":"2015","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.fsi.2015.06.027_bib55","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s10695-008-9218-1","article-title":"Cloning, characterization, and expression analysis of a CC chemokine gene from turbot (Scophthalmus maximus)","volume":"36","author":"Chen","year":"2010","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.fsi.2015.06.027_bib56","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.dci.2006.01.003","article-title":"Molecular and expression analysis of an interferon-gamma-inducible guanylate-binding protein from rainbow trout (Oncorhynchus mykiss)","volume":"30","author":"Robertsen","year":"2006","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib57","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1016\/j.fsi.2012.09.004","article-title":"Trout oral VP2 DNA vaccination mimics transcriptional responses occurring after infection with infectious pancreatic necrosis virus (IPNV)","volume":"33","author":"Ballesteros","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib58","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1128\/IAI.62.4.1268-1274.1994","article-title":"Streptococcal M6 protein binds to fucose-containing glycoproteins on cultured human epithelial cells","volume":"62","author":"Wang","year":"1994","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fsi.2015.06.027_bib59","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.fsi.2007.11.004","article-title":"Cloning and characterization of phospholipase D from olive flounder (Paralichthys olivaceus)","volume":"24","author":"Jeon","year":"2008","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2015.06.027_bib60","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/s00109-014-1157-y","article-title":"Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus","volume":"92","author":"Chang","year":"2014","journal-title":"J.\u00a0Mol. Med."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464815300565?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464815300565?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T02:50:35Z","timestamp":1599187835000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464815300565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":60,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S1050464815300565"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2015.06.027","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trancriptomic profiling revealed the signatures of acute immune response in tilapia (Oreochromis niloticus) following Streptococcus iniae challenge","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2015.06.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}