{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:26:20Z","timestamp":1784042780489,"version":"3.55.0"},"reference-count":119,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China (973 Program)","doi-asserted-by":"crossref","award":["2014CB138600"],"award-info":[{"award-number":["2014CB138600"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100013286","name":"Specialized Research Fund for the Doctoral Program of Higher Education of China","doi-asserted-by":"crossref","award":["20135103110001"],"award-info":[{"award-number":["20135103110001"]}],"id":[{"id":"10.13039\/501100013286","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Science and Technology Support Program of Sichuan Province of China","award":["2014NZ0003"],"award-info":[{"award-number":["2014NZ0003"]}]},{"name":"Major Scientific and Technological Achievement Transformation Project of Sichuan Province of China","award":["2012NC0007"],"award-info":[{"award-number":["2012NC0007"]}]},{"name":"Major Scientific and Technological Achievement Transformation Project of Sichuan Province of China","award":["2013NC0045"],"award-info":[{"award-number":["2013NC0045"]}]},{"name":"Demonstration of Major Scientific and Technological Achievement Transformation Project of Sichuan Province of China","award":["2015CC0011"],"award-info":[{"award-number":["2015CC0011"]}]},{"name":"Natural Science Foundation for Young Scientists of Sichuan Province","award":["2014JQ0007"],"award-info":[{"award-number":["2014JQ0007"]}]},{"name":"Sichuan Province Research Foundation for Basic Research","award":["2013JY0082"],"award-info":[{"award-number":["2013JY0082"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish &amp; Shellfish Immunology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.fsi.2016.07.020","type":"journal-article","created":{"date-parts":[[2016,7,16]],"date-time":"2016-07-16T06:04:47Z","timestamp":1468649087000},"page":"208-228","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":83,"special_numbering":"C","title":["Methionine hydroxy analogue enhanced fish immunity via modulation of NF-\u03baB, TOR, MLCK, MAPKs and Nrf2 signaling in young grass carp ( Ctenopharyngodon idella )"],"prefix":"10.1016","volume":"56","author":[{"given":"Fei-Yu","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Dan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Yao","family":"Kuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu-Neng","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-An","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Qiu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2016.07.020_bib1","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.fsi.2007.03.010","article-title":"Oral administration of Eclipta alba leaf aqueous extract enhances the non-specific immune responses and disease resistance of Oreochromis mossambicus","volume":"23","author":"Christybapita","year":"2007","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib2","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.anifeedsci.2011.12.015","article-title":"Fish immune system and its nutritional modulation for preventive health care","volume":"173","author":"Kiron","year":"2012","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.fsi.2016.07.020_bib3","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1023\/B:AQUI.0000004181.89420.a2","article-title":"Dietary methionine requirement of fingerling Indian major carp, Cirrhinus mrigala (Hamilton)","volume":"11","author":"Ahmed","year":"2003","journal-title":"Aquac. Int."},{"key":"10.1016\/j.fsi.2016.07.020_bib4","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1111\/j.1365-2095.2008.00613.x","article-title":"Effect of methionine on intestinal enzymes activities, microflora and humoral immune of juvenile Jian carp (Cyprinus carpio var. Jian)","volume":"15","author":"Tang","year":"2009","journal-title":"Aquac. Nutr."},{"key":"10.1016\/j.fsi.2016.07.020_bib5","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/j.1365-2109.2007.01704.x","article-title":"Expanding the utilization of sustainable plant products in aquafeeds: a review","volume":"38","author":"Gatlin","year":"2007","journal-title":"Aquac. Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib6","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.fsi.2014.11.024","article-title":"Dietary tryptophan and methionine as modulators of European seabass (Dicentrarchus labrax) immune status and inflammatory response","volume":"42","author":"Machado","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib7","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.aquaculture.2013.07.021","article-title":"Comparative study on the effects of L-methionine or 2-hydroxy-4-(methylthio) butanoic acid as dietary methionine source on growth performance and anti-oxidative responses of turbot (Psetta maxima)","volume":"412\u2013413","author":"Ma","year":"2013","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib8","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.fsi.2011.12.012","article-title":"Effects of graded levels of dietary methionine hydroxy analogue on immune response and antioxidant status of immune organs in juvenile Jian carp (Cyprinus carpio var. Jian)","volume":"32","author":"Kuang","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib9","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.fsi.2005.03.007","article-title":"Phylogeny and ontogeny of fish leucocytes","volume":"19","author":"Rombout","year":"2005","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib10","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1006\/fsim.1998.0181","article-title":"The morphology of the immune system in teleost fishes","volume":"9","author":"Press","year":"1999","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.peptides.2013.07.026","article-title":"Effects of recombinant trout leptin in superoxide production and NF-\u03baB\/MAPK phosphorylation in blood leukocytes","volume":"48","author":"Mariano","year":"2013","journal-title":"Peptides"},{"key":"10.1016\/j.fsi.2016.07.020_bib12","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.immuni.2008.08.012","article-title":"The TSC-mTOR signaling pathway regulates the innate inflammatory response","volume":"29","author":"Weichhart","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.fsi.2016.07.020_bib13","doi-asserted-by":"crossref","first-page":"6414","DOI":"10.4238\/2013.December.10.2","article-title":"Dietary methionine effects on IGF-I and GHR mRNA expression in broilers","volume":"12","author":"Del","year":"2013","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib14","doi-asserted-by":"crossref","first-page":"5583","DOI":"10.4049\/jimmunol.170.11.5583","article-title":"Wound healing and expression of antimicrobial peptides\/polypeptides in human keratinocytes, a consequence of common growth factors","volume":"170","author":"S\u00f8rensen","year":"2003","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib15","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1093\/ps\/85.11.1932","article-title":"Conversion of the methionine hydroxy analogue DL-2-hydroxy-(4-methylthio) butanoic acid to sulfur-containing amino acids in the chicken small intestine","volume":"85","author":"Venegas","year":"2006","journal-title":"Poult. Sci."},{"key":"10.1016\/j.fsi.2016.07.020_bib16","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.4049\/jimmunol.167.4.2275","article-title":"Taurine chloramine inhibits inducible nitric oxide synthase and TNF-\u03b1 gene expression in activated alveolar macrophages: decreased NF-\u03baB activation and I\u03baB kinase activity","volume":"167","author":"Barua","year":"2001","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib17","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1093\/jn\/114.9.1716","article-title":"Conversion of 2-hydroxy-4- (methylthio) butanoic acid to L-methionine in the chick: a stereospecific pathway","volume":"114","author":"Dibner","year":"1984","journal-title":"J.\u00a0Nutr."},{"key":"10.1016\/j.fsi.2016.07.020_bib18","doi-asserted-by":"crossref","first-page":"6717","DOI":"10.1016\/S0021-9258(18)32277-4","article-title":"Methionine synthesis from 5\u2032-S-methylthioadenosine. Resolution of enzyme activities and identification of 1-phospho-5-S-methylthioribulose","volume":"258","author":"Trackman","year":"1983","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2016.07.020_bib19","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1002\/hep.20154","article-title":"5\u2032-Methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes","volume":"39","author":"Hevia","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.fsi.2016.07.020_bib20","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/j.ijrobp.2009.08.034","article-title":"Radiation-induced interleukin-6 expression through MAPK\/p38\/NF-kappaB signaling pathway and the resultant antiapoptotic effect on endothelial cells through Mcl-1 expression with sIL6-Ralpha","volume":"75","author":"Chou","year":"2009","journal-title":"Int. J. Radiat. Oncol."},{"key":"10.1016\/j.fsi.2016.07.020_bib21","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1474-9726.2005.00152.x","article-title":"Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance","volume":"4","author":"Miller","year":"2005","journal-title":"Aging Cell"},{"key":"10.1016\/j.fsi.2016.07.020_bib22","doi-asserted-by":"crossref","first-page":"27975","DOI":"10.1074\/jbc.M204152200","article-title":"Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase\/target of rapamycin-dependent signaling pathway","volume":"277","author":"Treins","year":"2002","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2016.07.020_bib23","first-page":"277","article-title":"Fish immune system. A crossroads between innate and adaptive responses","volume":"22","author":"Tort","year":"2003","journal-title":"Inmunolog\u00eda"},{"key":"10.1016\/j.fsi.2016.07.020_bib24","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.fsi.2012.07.014","article-title":"The influence of dietary \u03b2-glucan, PAMP exposure and Aeromonas salmonicida on apoptosis modulation in common carp (Cyprinus carpio)","volume":"33","author":"Miest","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib25","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1083\/jcb.141.6.1423","article-title":"The regulation of reactive oxygen species production during programmed cell death","volume":"141","author":"Tan","year":"1998","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.fsi.2016.07.020_bib26","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1128\/MCB.26.1.221-229.2006","article-title":"Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1","volume":"26","author":"Kobayashi","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.fsi.2016.07.020_bib27","doi-asserted-by":"crossref","first-page":"3282","DOI":"10.1016\/j.chroma.2010.01.025","article-title":"Quantification of intermediates of the methionine and polyamine metabolism by liquid chromatography-tandem mass spectrometry in cultured tumor cells and liver biopsies","volume":"1217","author":"Stevens","year":"2010","journal-title":"J.\u00a0Chromatogr. A"},{"key":"10.1016\/j.fsi.2016.07.020_bib28","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.mehy.2011.07.014","article-title":"Spermidine may decrease ER stress in pancreatic beta cells and may reduce apoptosis via activating AMPK dependent autophagy pathway","volume":"77","author":"Tirupathi Pichiah","year":"2011","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.fsi.2016.07.020_bib29","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1079\/WPS20030006","article-title":"Review of the metabolism of 2-hydroxy-4- (methylthio) butanoic acid","volume":"59","author":"Dibner","year":"2003","journal-title":"World Poult. Sci. J."},{"key":"10.1016\/j.fsi.2016.07.020_bib30","doi-asserted-by":"crossref","first-page":"11908","DOI":"10.1073\/pnas.172398899","article-title":"Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants","volume":"99","author":"Dinkova-Kostova","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.fsi.2016.07.020_bib31","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1152\/physrev.00012.2005","article-title":"Signaling mechanisms regulating endothelial permeability","volume":"86","author":"Mehta","year":"2006","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.fsi.2016.07.020_bib32","doi-asserted-by":"crossref","first-page":"8237","DOI":"10.1073\/pnas.0908869107","article-title":"MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function","volume":"107","author":"Yu","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.fsi.2016.07.020_bib33","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s13105-015-0386-z","article-title":"Modulation by thyroid hormone of myosin light chain phosphorylation and aquaporin 5 protein expression in intact lung","volume":"71","author":"Pajouhi","year":"2015","journal-title":"J.\u00a0Physiol. Biochem."},{"key":"10.1016\/j.fsi.2016.07.020_bib34","series-title":"Statistical Yearbook 2013: World Food and Agriculture","author":"FAO","year":"2013"},{"key":"10.1016\/j.fsi.2016.07.020_bib35","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.aquaculture.2004.08.002","article-title":"Evaluation of different sulfur amino acid compounds in the diet of red drum, Sciaenops ocellatus, and sparing value of cystine for methionine","volume":"241","author":"Goff","year":"2004","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib36","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1111\/j.1365-2109.2006.01593.x","article-title":"Refined understanding of sulphur amino acid nutrition in hybrid striped bass, Morone chrysops \u2640\u00a0\u00d7 M.\u00a0saxatilis \u2642","volume":"37","author":"Kelly","year":"2006","journal-title":"Aquac. Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib37","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.aquaculture.2005.04.005","article-title":"Quantitative dietary lysine requirement of juvenile grass carp (Ctenopharyngodon idella)","volume":"249","author":"Wang","year":"2005","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib38","first-page":"2263","article-title":"Methionine requirement of grass carp (Ctenopharyngodon idell) during middle growth stage","volume":"24","author":"Tang","year":"2012","journal-title":"Chin. J. Anim. Nutr."},{"key":"10.1016\/j.fsi.2016.07.020_bib39","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1021\/jf00126a038","article-title":"Amino acid analysis of feedstuffs: determination of methionine and cystine after oxidation with performic acid and hydrolysis","volume":"6","author":"Spindler","year":"1984","journal-title":"J.\u00a0Agric. Food Chem."},{"key":"10.1016\/j.fsi.2016.07.020_bib40","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.fsi.2013.05.027","article-title":"Effects of dietary isoleucine on the immune response, antioxidant status and gene expression in the head kidney of juvenile Jian carp (Cyprinus carpio var. Jian)","volume":"35","author":"Zhao","year":"2013","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib41","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1365-2095.2011.00881.x","article-title":"Lipid peroxidation, protein oxidant and antioxidant status of muscle and serum for juvenile Jian carp (Cyprinus carpio var. Jian) fed grade levels of methionine hydroxy analogue","volume":"18","author":"Xiao","year":"2012","journal-title":"Aquac Nutr."},{"key":"10.1016\/j.fsi.2016.07.020_bib42","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/s12011-013-9785-6","article-title":"Effects of dietary copper on growth, digestive, and brush border enzyme activities and antioxidant defense of hepatopancreas and intestine for young grass carp (Ctenopharyngodon idella)","volume":"155","author":"Tang","year":"2013","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib43","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.fsi.2014.07.004","article-title":"Dietary tryptophan modulates intestinal immune response, barrier function, antioxidant status and gene expression of TOR and Nrf2 in young grass carp (Ctenopharyngodon idella)","volume":"40","author":"Wen","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib44","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1016\/j.fsi.2013.02.028","article-title":"Effects of mannan oligosaccharide on the physiological responses, HSP70 gene expression and disease resistance of Allogynogenetic crucian carp (Carassius auratus gibelio) under Aeromonas hydrophila infection","volume":"34","author":"Liu","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib45","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1016\/j.fsi.2013.08.005","article-title":"Effect of dietary supplemented andrographolide on growth, non-specific immune parameters and resistance against Aeromonas hydrophila in Labeo rohita (Hamilton)","volume":"35","author":"Basha","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib46","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.aquaculture.2014.08.015","article-title":"Aeromonas hydrophila induces intestinal inflammation in grass carp (Ctenopharyngodon idella): an experimental model","volume":"434","author":"Song","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib47","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.fsi.2007.10.007","article-title":"Role of the virulence plasmid pR99 and the metalloprotease Vvp in resistance of Vibrio vulnificus serovar E to eel innate immunity","volume":"24","author":"Valiente","year":"2008","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib48","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1111\/j.1365-2109.2009.02201.x","article-title":"Effects of dietary protein levels on the growth performance, digestive capacity and amino acid metabolism of juvenile Jian carp (Cyprinus carpio var. Jian)","volume":"40","author":"Liu","year":"2009","journal-title":"Aquac. Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib49","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1365-2095.2010.00818.x","article-title":"Effects of dietary methionine hydroxy analogue supplement on growth, protein deposition and intestine enzymes activities of juvennile Jian carp (Cyprinus carpio var. Jian)","volume":"17","author":"Xiao","year":"2011","journal-title":"Aquac. Nutr."},{"key":"10.1016\/j.fsi.2016.07.020_bib50","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.fsi.2010.01.017","article-title":"Immunomodulatory effect of dietary Saccharomyces cerevisiae, \u03b2-glucan and laminaran in mercuric chloride treated Nile tilapia (Oreochromis niloticus) and experimentally infected with Aeromonas hydrophila","volume":"28","author":"El-Boshy","year":"2010","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib51","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1177\/10.6.741","article-title":"Histochemical methods for acid phosphatase using hexazonium pararosanalin as coupler","volume":"10","author":"Classics","year":"1962","journal-title":"J.\u00a0Histochem. Cytochem"},{"key":"10.1016\/j.fsi.2016.07.020_bib52","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.aquaculture.2006.09.036","article-title":"Growth, immune function, and disease and stress resistance of juvenile Nile tilapia (Oreochromis niloticus) fed graded levels of bovine lactoferrin","volume":"262","author":"Welker","year":"2007","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib53","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0044-8486(93)90139-P","article-title":"Changes in an immunoglobulin M (IgM)-like protein during larval stages in tilapia, Oreochromis mossambicus","volume":"115","author":"Takemura","year":"1993","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib54","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1365-2095.2011.00853.x","article-title":"Methionine hydroxy analogue prevents oxidative damage and improves antioxidant status of intestine and hepatopancreas for juvenile Jian carp (Cyprinus carpio var. Jian)","volume":"17","author":"Feng","year":"2011","journal-title":"Aquac. Nutr."},{"key":"10.1016\/j.fsi.2016.07.020_bib55","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.fsi.2015.04.004","article-title":"Dietary riboflavin deficiency decreases immunity and antioxidant capacity, and changes tight junction proteins and related signaling molecules mRNA expression in the gills of young grass carp (Ctenopharyngodon idella)","volume":"45","author":"Chen","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib56","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.fsi.2011.05.018","article-title":"Effects of dietary \u03b2-glucan, mannan oligosaccharide and their combinations on growth performance, immunity and resistance against Vibrio splendidus of sea cucumber, Apostichopus japonicus","volume":"31","author":"Gu","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib57","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2016.07.020_bib58","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.fsi.2009.06.003","article-title":"Dietary supplementation of mannan oligosaccharide improves the immune responses and survival of marron, Cherax tenuimanus (Smith, 1912) when challenged with different stressors","volume":"27","author":"Sang","year":"2009","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib59","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.fsi.2011.06.006","article-title":"Effects of dietary chitosan and Bacillus subtilis on the growth performance, non-specific immunity and disease resistance of cobia, Rachycentron canadum","volume":"31","author":"Geng","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib60","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1017\/S0007114511005459","article-title":"Effect of dietary arginine on growth, intestinal enzyme activities and gene expression in muscle, hepatopancreas and intestine of juvenile Jian carp (Cyprinus carpio var. Jian)","volume":"108","author":"Chen","year":"2012","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.fsi.2016.07.020_bib61","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.aquaculture.2010.12.011","article-title":"Assessment of dietary lysine requirement for silver perch (Bidyanus bidyanus) juveniles","volume":"312","author":"Yang","year":"2011","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib62","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.aquaculture.2004.10.026","article-title":"Dietary l-ascorbic acid affects growth, nonspecific immune responses and disease resistance in juvenile grouper, Epinephelus malabaricus","volume":"244","author":"Lin","year":"2005","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib63","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.fsi.2004.09.006","article-title":"Innate immunity of fish (overview)","volume":"20","author":"Magnad\u00f3ttir","year":"2006","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib64","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.fsi.2014.10.005","article-title":"Effects of dietary fructooligosaccharide levels and feeding modes on growth, immune responses, antioxidant capability and disease resistance of blunt snout bream (Megalobrama amblycephala)","volume":"41","author":"Zhang","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib65","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/0955-2863(90)90070-2","article-title":"Methionine metabolism in mammals","author":"Finkelstein","year":"1990","journal-title":"J.\u00a0Nutr. Biochem."},{"key":"10.1016\/j.fsi.2016.07.020_bib66","doi-asserted-by":"crossref","first-page":"486","DOI":"10.17221\/3294-VETMED","article-title":"Innate and adaptive immunity in teleost fish: a review","volume":"56","author":"Uribe","year":"2011","journal-title":"Vet. Med-Czech"},{"key":"10.1016\/j.fsi.2016.07.020_bib67","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.aquaculture.2014.03.020","article-title":"Effects of dietary arachidonic acid (ARA) on lipid metabolism and health status of juvenile grass carp, Ctenopharyngodon idellus","volume":"430","author":"Tian","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2016.07.020_bib68","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.4049\/jimmunol.170.4.2106","article-title":"IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger","volume":"170","author":"Ferretti","year":"2003","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib69","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.fsi.2011.07.008","article-title":"The expression analysis of inflammatory and antimicrobial genes in the goldfish (Carassius auratus L.) infected with Trypanosoma carassii","volume":"31","author":"Oladiran","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib70","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.dci.2012.05.005","article-title":"Diversification of IFN\u03b3-inducible CXCb chemokines in cyprinid fish","volume":"38","author":"van der Aa","year":"2012","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib71","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S0022-3476(77)80692-6","article-title":"Milk protein quantity and quality in low-birth-weight infants. III. Effects on sulfur amino acids in plasma and urine","volume":"90","author":"Gaull","year":"1977","journal-title":"J.\u00a0Pediatr."},{"key":"10.1016\/j.fsi.2016.07.020_bib72","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1002\/1529-0131(200010)43:10<2169::AID-ANR4>3.0.CO;2-#","article-title":"The mechanism of taurine chloramine inhibition of cytokine (interleukin-6, interleukin-8) production by rheumatoid arthritis fibroblast-like synoviocytes","volume":"43","author":"Kontny","year":"2000","journal-title":"Arthritis Rheum-US"},{"key":"10.1016\/j.fsi.2016.07.020_bib73","doi-asserted-by":"crossref","first-page":"29233","DOI":"10.1074\/jbc.M501670200","article-title":"NIBP, a novel NIK and IKK-binding protein that enhances NF-\u03baB activation","volume":"280","author":"Hu","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2016.07.020_bib74","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S1074-7613(02)00423-5","article-title":"The lymphotoxin-\u03b2 receptor induces different patterns of gene expression via two NF-\u03baB pathways","volume":"17","author":"Dejardin","year":"2002","journal-title":"Immunity"},{"key":"10.1016\/j.fsi.2016.07.020_bib75","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1002\/1529-0131(200006)43:6<1244::AID-ANR7>3.0.CO;2-2","article-title":"Macrophage-derived cytokine and nuclear factor kappaB p65 expression in synovial membrane and skin of patients with psoriatic arthritis","volume":"43","author":"Danning","year":"2000","journal-title":"Arthritis Rheum-US"},{"key":"10.1016\/j.fsi.2016.07.020_bib76","first-page":"75","article-title":"Substance P induces TNF-\u03b1 and IL-6 production through NF\u03baB in peritoneal mast cells","volume":"1643","author":"Azzolina","year":"2003","journal-title":"BBA Mol. Cell Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib77","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1172\/JCI0215254","article-title":"Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation","volume":"110","author":"Hilliard","year":"2002","journal-title":"J.\u00a0Clin. Investig."},{"key":"10.1016\/j.fsi.2016.07.020_bib78","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.4049\/jimmunol.168.6.2590","article-title":"Cutting edge: identification of c-Rel-dependent and -independent pathways of IL-12 production during infectious and inflammatory stimuli","volume":"168","author":"Mason","year":"2002","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib79","doi-asserted-by":"crossref","first-page":"10964","DOI":"10.1074\/jbc.M407874200","article-title":"Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway","volume":"280","author":"Shi","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2016.07.020_bib80","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1023\/A:1024918328162","article-title":"The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc","volume":"250","author":"Li","year":"2003","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.fsi.2016.07.020_bib81","doi-asserted-by":"crossref","first-page":"4983","DOI":"10.1158\/0008-5472.CAN-08-4882","article-title":"N-myc downstream regulated gene 1\/cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of \u03baB kinase \u03b2 expression","volume":"69","author":"Hosoi","year":"2009","journal-title":"Cancer Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib82","doi-asserted-by":"crossref","first-page":"3466","DOI":"10.1182\/blood.V97.11.3466","article-title":"Prostaglandin E2 is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer","volume":"97","author":"Kali\u0144ski","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.fsi.2016.07.020_bib83","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/PL00000199","article-title":"Differential anti-inflammatory effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production","volume":"49","author":"Attur","year":"2000","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib84","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.cell.2012.03.017","article-title":"mTOR signaling in growth control and disease","volume":"149","author":"Laplante","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.fsi.2016.07.020_bib85","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/1521-4141(200201)32:1<261::AID-IMMU261>3.0.CO;2-X","article-title":"Contrasting roles of IL12p40 and IL12p35 in the development of hapten-induced colitis","volume":"32","author":"Camoglio","year":"2002","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib86","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.molimm.2011.02.014","article-title":"Constitutive high expression of interleukin-4\/13A and GATA-3 in gill and skin of salmonid fishes suggests that these tissues form Th2-skewed immune environments","volume":"48","author":"Takizawa","year":"2011","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib87","doi-asserted-by":"crossref","first-page":"G529","DOI":"10.1152\/ajpgi.00050.2003","article-title":"Regulation of IL-11 expression in intestinal myofibroblasts: role of c-Jun AP-1- and MAPK-dependent pathways","volume":"285","author":"Bamba","year":"2003","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.fsi.2016.07.020_bib88","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.4049\/jimmunol.0902544","article-title":"TCR-dependent translational control of GATA-3 enhances Th2 differentiation","volume":"185","author":"Cook","year":"2010","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib89","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s00251-008-0299-x","article-title":"Comprehensive clarification of two paralogous interleukin 4\/13 loci in teleost fish","volume":"60","author":"Ohtani","year":"2008","journal-title":"Immunogenetics"},{"key":"10.1016\/j.fsi.2016.07.020_bib90","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1046\/j.1440-1711.2000.00929.x","article-title":"Insulin induces epidermal growth factor (EGF) receptor clustering and potentiates EGF-stimulated DNA synthesis in Swiss 3T3 cells: a mechanism for costimulation in mitogenic synergy","volume":"78","author":"Crouch","year":"2000","journal-title":"Immunol. Cell Biol."},{"key":"10.1016\/j.fsi.2016.07.020_bib91","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1095\/biolreprod60.6.1304","article-title":"Expression and action of transforming growth factor beta (TGF\u03b21, TGF\u03b22, and TGF\u03b23) during embryonic rat testis development1","volume":"60","author":"Cupp","year":"1999","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.fsi.2016.07.020_bib92","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1126\/science.281.5381.1312","article-title":"Caspases: enemies within","volume":"281","author":"Thornberry","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.fsi.2016.07.020_bib93","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/82732","article-title":"Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule","volume":"1","author":"Holler","year":"2000","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib94","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nrm2308","article-title":"The Bcl-2 protein family: opposing activities that mediate cell death","volume":"9","author":"Youle","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.fsi.2016.07.020_bib95","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s10495-006-4689-y","article-title":"JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL\/caspase-8 and mitochondria-dependent pathways","volume":"11","author":"Lauricella","year":"2006","journal-title":"Apoptosis"},{"key":"10.1016\/j.fsi.2016.07.020_bib96","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0891-5849(00)00302-6","article-title":"Triggering and modulation of apoptosis by oxidative stress","volume":"29","author":"Chandraa","year":"2000","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.fsi.2016.07.020_bib97","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/(SICI)1099-0844(200006)18:2<77::AID-CBF851>3.0.CO;2-Z","article-title":"Allergy to drugs: antioxidant enzymic activities, lipid peroxidation and protein oxidative damage in human blood","volume":"18","author":"Mates","year":"2000","journal-title":"Cell Biochem. Funct."},{"key":"10.1016\/j.fsi.2016.07.020_bib98","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.chemosphere.2003.10.048","article-title":"Effects of chronic exposure of 2,4-dichlorophenol on the antioxidant system in liver of freshwater fish Carassius auratus","volume":"55","author":"Zhang","year":"2004","journal-title":"Chemosphere"},{"key":"10.1016\/j.fsi.2016.07.020_bib99","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.mad.2006.12.006","article-title":"Effects of aerobic exercise training on antioxidant enzyme activities and mRNA levels in soleus muscle from young and aged rats","volume":"128","author":"Lambertucci","year":"2007","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.fsi.2016.07.020_bib100","doi-asserted-by":"crossref","first-page":"18959","DOI":"10.1074\/jbc.273.30.18959","article-title":"Effects of glucose and insulin on rat apolipoprotein A-I gene expression","volume":"273","author":"Murao","year":"1998","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2016.07.020_bib101","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1002\/ijc.26079","article-title":"D-4F, an apoA-I mimetic peptide, inhibits proliferation and tumorigenicity of epithelial ovarian cancer cells by upregulating the antioxidant enzyme MnSOD","volume":"130","author":"Ganapathy","year":"2012","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.fsi.2016.07.020_bib102","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1128\/MCB.01080-08","article-title":"The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds","volume":"29","author":"Kobayashi","year":"2008","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.fsi.2016.07.020_bib103","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0002-9343(87)90860-6","article-title":"Neuropharmacology of S-adenosyl-L-methionine","volume":"83","author":"Baldessarini","year":"1987","journal-title":"Am. J. Med."},{"key":"10.1016\/j.fsi.2016.07.020_bib104","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.fsi.2015.08.024","article-title":"Exogenous phospholipids supplementation improves growth and modulates immune response and physical barrier referring to NF-\u03baB, TOR, MLCK and Nrf2 signaling factors in the intestine of juvenile grass carp (Ctenopharyngodon idella)","volume":"47","author":"Chen","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.07.020_bib105","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1128\/MCB.01591-09","article-title":"Genetic analysis of cytoprotective functions supported by graded expression of Keap1","volume":"30","author":"Taguchi","year":"2010","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.fsi.2016.07.020_bib106","doi-asserted-by":"crossref","first-page":"L1094","DOI":"10.1152\/ajplung.2001.280.6.L1094","article-title":"IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways","volume":"280","author":"Schraufstatter","year":"2001","journal-title":"Am. J. Physiol. Lung C"},{"key":"10.1016\/j.fsi.2016.07.020_bib107","doi-asserted-by":"crossref","first-page":"4615","DOI":"10.1242\/jcs.00755","article-title":"Potential role of MCP-1 in endothelial cell tight junction \u2018opening\u2019: signaling via Rho and Rho kinase","volume":"116","author":"Stamatovic","year":"2003","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.fsi.2016.07.020_bib108","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1242\/jcs.02406","article-title":"Overexpression of claudin-7 decreases the paracellular Cl\u2212 conductance and increases the paracellular Na+ conductance in LLC-PK1 cells","volume":"118","author":"Alexandre","year":"2005","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.fsi.2016.07.020_bib109","doi-asserted-by":"crossref","first-page":"F1078","DOI":"10.1152\/ajprenal.00116.2003","article-title":"Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins","volume":"285","author":"Van Itallie","year":"2003","journal-title":"Am. J. Physiol. Renal"},{"key":"10.1016\/j.fsi.2016.07.020_bib110","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/japr\/14.1.147","article-title":"Influence of dietary sodium level on utilization of methionine from DL-methionine and liquid methionine-hydroxy analogue","volume":"14","author":"Motl","year":"2005","journal-title":"J.\u00a0Appl. Poult. Res."},{"key":"10.1016\/j.fsi.2016.07.020_bib111","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.vetmic.2012.10.033","article-title":"Cyprinid herpesvirus 3 infection disrupts the skin barrier of common carp (Cyprinus carpio L.)","volume":"162","author":"Adamek","year":"2013","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.fsi.2016.07.020_bib112","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.procbio.2005.08.010","article-title":"Production and characterisation of alginate microparticles incorporating Aeromonas hydrophila designed for fish oral vaccination","volume":"41","author":"Rodrigues","year":"2006","journal-title":"Process Biochem."},{"key":"10.1016\/j.fsi.2016.07.020_bib113","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/j.vaccine.2010.12.069","article-title":"Application of ultrasound in vaccination against goldfish ulcer disease: a pilot study","volume":"29","author":"Navot","year":"2011","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2016.07.020_bib114","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1016\/j.foodchem.2013.04.081","article-title":"The methionine precursor dl-2-hydroxy-(4-methylthio) butanoic acid protects intestinal epithelial barrier function","volume":"141","author":"Venegas","year":"2013","journal-title":"Food Chem."},{"key":"10.1016\/j.fsi.2016.07.020_bib115","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.taap.2009.07.008","article-title":"Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: role of NF-\u03baB, p38 and JNK MAPK pathway","volume":"240","author":"Ghosh","year":"2009","journal-title":"Toxicol. Appl. Pharm."},{"key":"10.1016\/j.fsi.2016.07.020_bib116","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1179\/135100003125001260","article-title":"Redox regulation of homocysteine-dependent glutathione synthesis","volume":"8","author":"Vitvitsky","year":"2003","journal-title":"Redox Rep."},{"key":"10.1016\/j.fsi.2016.07.020_bib117","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1093\/ps\/86.9.1995","article-title":"Research note effect of excess methionine and methionine hydroxy analogue on growth performance and plasma homocysteine of growing Pekin ducks","volume":"86","author":"Xie","year":"2007","journal-title":"Poult. Sci."},{"key":"10.1016\/j.fsi.2016.07.020_bib118","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.neuroscience.2013.07.051","article-title":"Hydrogen sulfide attenuates neurodegeneration and neurovascular dysfunction induced by intracerebral-administered homocysteine in mice","volume":"252","author":"Kamat","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.fsi.2016.07.020_bib119","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1182\/blood-2011-02-338269","article-title":"Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions","volume":"118","author":"Beard","year":"2011","journal-title":"Blood"}],"container-title":["Fish &amp; Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464816304429?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464816304429?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T04:53:40Z","timestamp":1656824020000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464816304429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":119,"alternative-id":["S1050464816304429"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2016.07.020","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Methionine hydroxy analogue enhanced fish immunity via modulation of NF-\u03baB, TOR, MLCK, MAPKs and Nrf2 signaling in young grass carp (Ctenopharyngodon idella)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2016.07.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}