{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:31:57Z","timestamp":1790771517741,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31330081"],"award-info":[{"award-number":["31330081"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Qingdao National Laboratory for Marine Science and Technology","award":["2015ASKJ02"],"award-info":[{"award-number":["2015ASKJ02"]}]},{"name":"Taishan Scholar Program of Shandong Province"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.fsi.2016.08.047","type":"journal-article","created":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T00:55:47Z","timestamp":1472172947000},"page":"340-349","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Molecular characterization reveals involvement of four caspases in the antibacterial immunity of tongue sole ( Cynoglossus semilaevis )"],"prefix":"10.1016","volume":"57","author":[{"given":"Hao","family":"Long","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2016.08.047_bib1","doi-asserted-by":"crossref","first-page":"a008656","DOI":"10.1101\/cshperspect.a008656","article-title":"Caspase functions in cell death and disease","volume":"5","author":"McIlwain","year":"2013","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.fsi.2016.08.047_bib2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1146\/annurev.immunol.021908.132715","article-title":"The inflammasomes: guardians of the body","volume":"27","author":"Martinon","year":"2009","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/BST0360001","article-title":"Caspase activation cascades in apoptosis","volume":"36","author":"Logue","year":"2008","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.fsi.2016.08.047_bib4","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1159\/000283688","article-title":"Inflammatory caspases in innate immunity and inflammation","volume":"2","author":"Yazdi","year":"2010","journal-title":"J.\u00a0Innate Immun."},{"issue":"4","key":"10.1016\/j.fsi.2016.08.047_bib5","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00281-015-0494-4","article-title":"Caspase-1: an integral regulator of innate immunity","volume":"37","author":"Winkler","year":"2015","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.fsi.2016.08.047_bib6","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/cdd.2014.216","article-title":"Old, new and emerging functions of caspases","volume":"22","author":"Shalini","year":"2015","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.fsi.2016.08.047_bib7","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/sj.cdd.4401175","article-title":"Caspase-2 redux","volume":"10","author":"Troy","year":"2003","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.fsi.2016.08.047_bib8","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1007\/s10495-015-1161-x","article-title":"An epistatic effect of apaf-1 and caspase-9 on chlamydial infection","volume":"20","author":"Rahman","year":"2015","journal-title":"Apoptosis"},{"key":"10.1016\/j.fsi.2016.08.047_bib9","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.smim.2014.03.005","article-title":"Functions of caspase 8: the identified and the mysterious","volume":"26","author":"Salvesen","year":"2014","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib10","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1172\/JCI26252","article-title":"Caspases: pharmacological manipulation of cell death","volume":"115","author":"Lavrik","year":"2005","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.fsi.2016.08.047_bib11","first-page":"271","article-title":"Swords of cell death: caspase activation and regulation","volume":"11","author":"Alenzi","year":"2010","journal-title":"Asian Pac J. Cancer Prev."},{"key":"10.1016\/j.fsi.2016.08.047_bib12","doi-asserted-by":"crossref","first-page":"e50450","DOI":"10.1371\/journal.pone.0050450","article-title":"Caspase-1 and IL-1beta processing in a teleost fish","volume":"7","author":"Reis","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.fsi.2016.08.047_bib13","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.molimm.2006.04.028","article-title":"Molecular cloning and characterisation of sea bass (Dicentrarchus labrax L.) caspase-3 gene","volume":"44","author":"Reis","year":"2007","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib14","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1042\/bj3600039","article-title":"Characterization of zebrafish caspase-3 and induction of apoptosis through ceramide generation in fish fathead minnow tailbud cells and zebrafish embryo","volume":"360","author":"Yabu","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.fsi.2016.08.047_bib15","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.fsi.2011.01.018","article-title":"Molecular cloning and characterization of caspase-3 in large yellow croaker (Pseudosciaena crocea)","volume":"30","author":"Li","year":"2011","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib16","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.cbpb.2006.02.006","article-title":"Cloning and characterization of the executioner caspases 3, 6, 7 and Hsp70 in hyperthermic Atlantic salmon (Salmo salar) embryos","volume":"144","author":"Takle","year":"2006","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.fsi.2016.08.047_bib17","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1093\/genetics\/154.4.1773","article-title":"A\u00a0detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolution","volume":"154","author":"Naruse","year":"2000","journal-title":"Genetics"},{"key":"10.1016\/j.fsi.2016.08.047_bib18","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.fsi.2012.04.008","article-title":"Caspase 3 from rock bream (Oplegnathus fasciatus): genomic characterization and transcriptional profiling upon bacterial and viral inductions","volume":"33","author":"Elvitigala","year":"2012","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib19","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.fsi.2016.01.008","article-title":"Multifunctional murrel caspase 1, 2, 3, 8 and 9: conservation, uniqueness and their pathogen-induced expression pattern","volume":"49","author":"Kumaresan","year":"2016","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib20","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.fsi.2014.01.013","article-title":"Antibacterial and antiviral properties of tongue sole (Cynoglossus semilaevis) high mobility group B2 protein are largely independent on the acidic C-terminal domain","volume":"37","author":"Long","year":"2014","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib21","doi-asserted-by":"crossref","first-page":"3882","DOI":"10.1128\/AEM.02690-08","article-title":"Attenuation of Edwardsiella tarda virulence by small peptides that interfere with LuxS\/autoinducer type 2 quorum sensing","volume":"75","author":"Zhang","year":"2009","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.fsi.2016.08.047_bib22","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.fsi.2014.09.006","article-title":"CsIFIT1, an interferon-induced protein with tetratricopeptide repeat, inhibits viral infection in tongue sole (Cynoglossus semilaevis)","volume":"41","author":"Long","year":"2014","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib23","doi-asserted-by":"crossref","first-page":"5195","DOI":"10.1016\/j.vaccine.2009.06.071","article-title":"Construction and evaluation of DNA vaccines encoding Edwardsiella tarda antigens","volume":"27","author":"Jiao","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2016.08.047_bib24","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.dci.2015.10.002","article-title":"CsSAP, a teleost serum amyloid P component, interacts with bacteria, promotes phagocytosis, and enhances host resistance against bacterial and viral infection","volume":"55","author":"Wang","year":"2016","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.yexmp.2015.05.004","article-title":"Quantitative analysis of the expression of caspase 3 and caspase 9 in different types of atherosclerotic lesions in the human aorta","volume":"99","author":"Sobenin","year":"2015","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.fsi.2016.08.047_bib26","doi-asserted-by":"crossref","first-page":"10948","DOI":"10.1073\/pnas.1833375100","article-title":"Bacterial pathogens modulate an apoptosis differentiation program in human neutrophils","volume":"100","author":"Kobayashi","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.fsi.2016.08.047_bib27","doi-asserted-by":"crossref","first-page":"L899","DOI":"10.1152\/ajplung.00338.2002","article-title":"Mechanisms of bacterial lipopolysaccharide-induced endothelial apoptosis","volume":"284","author":"Bannerman","year":"2003","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.fsi.2016.08.047_bib28","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.tim.2008.02.001","article-title":"Staying alive: bacterial inhibition of apoptosis during infection","volume":"16","author":"Faherty","year":"2008","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.fsi.2016.08.047_bib29","doi-asserted-by":"crossref","first-page":"4570","DOI":"10.1128\/IAI.72.8.4570-4578.2004","article-title":"Uropathogenic Escherichia coli triggers oxygen-dependent apoptosis in human neutrophils through the cooperative effect of type 1 fimbriae and lipopolysaccharide","volume":"72","author":"Blomgran","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fsi.2016.08.047_bib30","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1046\/j.1365-2958.2003.03313.x","article-title":"Unravelling the biology of macrophage infection by gene expression profiling of intracellular Salmonella enterica","volume":"47","author":"Eriksson","year":"2003","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fsi.2016.08.047_bib31","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1365-2958.2006.05271.x","article-title":"In\u00a0vivo, fliC expression by Salmonella enterica serovar Typhimurium is heterogeneous, regulated by ClpX, and anatomically restricted","volume":"61","author":"Cummings","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fsi.2016.08.047_bib32","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00430-005-0239-4","article-title":"Apoptosis in infectious disease: how bacteria interfere with the apoptotic apparatus","volume":"195","author":"Hacker","year":"2006","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.fsi.2016.08.047_bib33","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jinf.2005.12.028","article-title":"Inhibition of staurosporine-induced activation of the proapoptotic multidomain Bcl-2 proteins Bax and Bak by three invasive chlamydial species","volume":"53","author":"Zhong","year":"2006","journal-title":"J.\u00a0Infect."},{"key":"10.1016\/j.fsi.2016.08.047_bib34","doi-asserted-by":"crossref","first-page":"5339","DOI":"10.1128\/IAI.73.9.5339-5349.2005","article-title":"Incomplete activation of macrophage apoptosis during intracellular replication of Legionella pneumophila","volume":"73","author":"Abu-Zant","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fsi.2016.08.047_bib35","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.micinf.2011.08.005","article-title":"Edwardsiella tarda - virulence mechanisms of an emerging gastroenteritis pathogen","volume":"14","author":"Leung","year":"2012","journal-title":"Microbes Infect."},{"key":"10.1016\/j.fsi.2016.08.047_bib36","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1297-9716-43-67","article-title":"Pathogenesis of and strategies for preventing Edwardsiella tarda infection in fish","volume":"43","author":"Park","year":"2012","journal-title":"Vet. Res."},{"key":"10.1016\/j.fsi.2016.08.047_bib37","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.micpath.2006.08.002","article-title":"Intracellular replication of Edwardsiella tarda in murine macrophage is dependent on the type III secretion system and induces an up-regulation of anti-apoptotic NF-kappaB target genes protecting the macrophage from staurosporine-induced apoptosis","volume":"41","author":"Okuda","year":"2006","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.fsi.2016.08.047_bib38","article-title":"Edwardsiella tarda-induced inhibition of apoptosis: a strategy for intracellular survival","author":"Zhou","year":"2016","journal-title":"Front. Cell. Infect. Microbiol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464816305319?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464816305319?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T02:20:59Z","timestamp":1657160459000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464816305319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":38,"alternative-id":["S1050464816305319"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2016.08.047","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular characterization reveals involvement of four caspases in the antibacterial immunity of tongue sole (Cynoglossus semilaevis)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2016.08.047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}