{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:22:03Z","timestamp":1760955723138},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Chinese Major State Basic Research Development Program","award":["Grant2013CB835304"],"award-info":[{"award-number":["Grant2013CB835304"]}]},{"name":"Marine Public Welfare Project of State Oceanic Administration","award":["201305016"],"award-info":[{"award-number":["201305016"]}]},{"DOI":"10.13039\/501100001809","name":"Chinese National Natural Science Foundation","doi-asserted-by":"crossref","award":["31170353","31202020"],"award-info":[{"award-number":["31170353","31202020"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Research Project of Liaoning Provincial Department of Education","award":["LJQ2014117"],"award-info":[{"award-number":["LJQ2014117"]}]},{"name":"Science and Technology Project of Dalian","award":["2013E11SF056"],"award-info":[{"award-number":["2013E11SF056"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1016\/j.fsi.2017.06.061","type":"journal-article","created":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T01:47:31Z","timestamp":1499219251000},"page":"286-294","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Identification and characterization of the lamprey Flotillin-1 gene with a role in cell adhesion"],"prefix":"10.1016","volume":"71","author":[{"given":"Rong","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoping","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Pang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingwei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2017.06.061_bib1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/35036052","article-title":"Lipid rafts and signal transduction","volume":"1","author":"Simons","year":"2000","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.fsi.2017.06.061_bib2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/S0955-0674(00)00238-6","article-title":"Roles of lipid rafts in membrane transport","volume":"13","author":"Ikonen","year":"2001","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.fsi.2017.06.061_bib3","doi-asserted-by":"crossref","first-page":"13793","DOI":"10.1074\/jbc.272.21.13793","article-title":"Flotillin and epidermal surface eantigen define a new family of caveolae-associat edintegral membrane proteins","volume":"272","author":"Bickel","year":"1997","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2017.06.061_bib4","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1242\/jcs.092015","article-title":"The roles of flotillin microdomains\u2013endocytosis and beyond","volume":"124","author":"Otto","year":"2011","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.fsi.2017.06.061_bib5","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1242\/dev.124.2.577","article-title":"Reggie-1 and reggie-2, two cell surface proteins expressed by retinal ganglion cells during axon regeneration","volume":"124","author":"Schulte","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.fsi.2017.06.061_bib6","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s00018-005-5434-3","article-title":"Ancient origin of reggie (flotillin), reggie-like, and other lipid-raft proteins: convergent evolution of the SPFH domain","volume":"63","author":"Rivera-Milla","year":"2006","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.fsi.2017.06.061_bib7","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.tcb.2007.06.005","article-title":"The SPFH domain-containing proteins: more than lipid raft markers","volume":"17","author":"Browman","year":"2007","journal-title":"Trends Cell Biol."},{"issue":"50","key":"10.1016\/j.fsi.2017.06.061_bib8","doi-asserted-by":"crossref","first-page":"48834","DOI":"10.1074\/jbc.M209082200","article-title":"Flotillin-1\/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation","volume":"277","author":"Morrow","year":"2002","journal-title":"J.\u00a0Biol. Chem."},{"issue":"16","key":"10.1016\/j.fsi.2017.06.061_bib9","doi-asserted-by":"crossref","first-page":"16125","DOI":"10.1074\/jbc.M500940200","article-title":"The stomatin\/prohibitin\/flotillin\/HflK\/C domain of Flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3-L1a dipocytes","volume":"280","author":"Liu","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2017.06.061_bib10","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1042\/BJ20061686","article-title":"Rules for reggie oligomerization and stabilization","volume":"403","author":"Solis","year":"2007","journal-title":"Biochem. J."},{"issue":"Pt3","key":"10.1016\/j.fsi.2017.06.061_bib11","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1242\/jcs.03336","article-title":"Role of EGF-induced tyrosine phosphorylation of reggie-1\/flotillin-2 in cell spreading and signaling to the actin cytoskeleton","volume":"120","author":"Neumann-Giesen","year":"2007","journal-title":"J.\u00a0Cell Sci."},{"issue":"Pt7","key":"10.1016\/j.fsi.2017.06.061_bib12","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1242\/jcs.039024","article-title":"Endocytosis of Flotillin-1 and flotillin-2 is regulated by Fyn kinase","volume":"122","author":"Riento","year":"2009","journal-title":"J.\u00a0Cell Sci."},{"issue":"17","key":"10.1016\/j.fsi.2017.06.061_bib13","doi-asserted-by":"crossref","first-page":"3792","DOI":"10.1091\/mbc.E09-04-0275","article-title":"Basolateral internalization of GPI-anchored proteins occurs via a clathrin-independent flotillin-dependent pathway in polarized hepatic cells","volume":"20","author":"A\u00eft-Slimane","year":"2009","journal-title":"Mol. Biol. Cell"},{"issue":"4","key":"10.1016\/j.fsi.2017.06.061_bib14","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/nn.2781","article-title":"Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT","volume":"14","author":"Cremona","year":"2011","journal-title":"Nat. Neurosci."},{"issue":"6927","key":"10.1016\/j.fsi.2017.06.061_bib15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/nature01451","article-title":"Regulated portals of entry into the cell","volume":"422","author":"Conner","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.fsi.2017.06.061_bib16","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s00395-014-0439-4","article-title":"Benjamin J Nichols, Ritva Tikkanen, Ralf P Brandes. Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells","volume":"109","author":"Christian","year":"2014","journal-title":"Basic Res. Cardiol."},{"issue":"6801","key":"10.1016\/j.fsi.2017.06.061_bib17","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/35025089","article-title":"CAP defines a second signalling pathway required for insulin-stimulated glucose transport","volume":"407","author":"Baumann","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.fsi.2017.06.061_bib18","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.cellsig.2009.03.012","article-title":"Hetero-oligomerization of reggie-1\/flotillin-2 and reggie-2\/Flotillin-1 is required for their endocytosis","volume":"21","author":"Babuke","year":"2009","journal-title":"Cell Signal."},{"key":"10.1016\/j.fsi.2017.06.061_bib19","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.coi.2007.08.003","article-title":"Evolution and development of immunological structures in the lamprey","volume":"19","author":"Amemiya","year":"2007","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.fsi.2017.06.061_bib20","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1126\/science.1162484","article-title":"Antigen recognition by variable lymphocyte receptors","volume":"321","author":"Han","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.fsi.2017.06.061_bib21","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.imlet.2015.02.006","article-title":"Identification and characterization of the lamprey IRF gene","volume":"164","author":"Pang","year":"2015","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.fsi.2017.06.061_bib22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0005-2736(81)90512-5","article-title":"Exfoliation of membrane ecto-enzymes in the form of microvesicles","volume":"645","author":"Trams","year":"1981","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.fsi.2017.06.061_bib23","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0005-2736(93)90098-K","article-title":"Identification of the phosphorylation site on human erythrocyte band 7 integral membrane protein: implications for a monotopic protein structure","volume":"1151","author":"Salzer","year":"1993","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.fsi.2017.06.061_bib24","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0002-9440(10)64357-X","article-title":"Podocin localizes in the kidney to the slit diaphragm area","volume":"160","author":"Roselli","year":"2002","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.fsi.2017.06.061_bib25","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/378292a0","article-title":"Stomatin-like protein necessary for mechanosensation in C. elegans","volume":"378","author":"Huang","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.fsi.2017.06.061_bib26","doi-asserted-by":"crossref","first-page":"29579","DOI":"10.1074\/jbc.M002339200","article-title":"Prohibitins, stomatins, and plant disease response genes compose a protein superfamily that controls cell proliferation, ion channel regulation, and death","volume":"275","author":"Nadimpalli","year":"2000","journal-title":"J.\u00a0Biol. Chem."},{"issue":"13","key":"10.1016\/j.fsi.2017.06.061_bib27","doi-asserted-by":"crossref","first-page":"4336","DOI":"10.1182\/blood-2003-03-0871","article-title":"Lipid raft-associated protein sorting in exosomes","volume":"102","author":"De Gassart","year":"2003","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.fsi.2017.06.061_bib28","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1242\/jcs.03336","article-title":"Role of EGF-induced tyrosine phosphorylation of reggie-1\/flotillin-2 in cell spreading and signaling to the actin cytoskeleton","volume":"120","author":"Neumann-Giesen","year":"2007","journal-title":"J.\u00a0Cell Sci."},{"issue":"24","key":"10.1016\/j.fsi.2017.06.061_bib29","doi-asserted-by":"crossref","first-page":"5139","DOI":"10.1242\/jcs.159764","article-title":"Flotillins in intercellular adhesion - from cellular physiology to human diseases","volume":"127","author":"Bodin","year":"2014","journal-title":"J.\u00a0Cell Sci."},{"issue":"11","key":"10.1016\/j.fsi.2017.06.061_bib30","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1002\/ijc.28927","article-title":"Vascular cell adhesion molecule-1 (VCAM-1)\u2013an increasing insight into its role in tumorigenicity and metastasis","volume":"136","author":"Schlesinger","year":"2015","journal-title":"Int. J. Cancer"},{"issue":"1","key":"10.1016\/j.fsi.2017.06.061_bib31","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S1734-1140(09)70004-0","article-title":"ICAM-1 signaling in endothelial cells","volume":"61","author":"Lawson","year":"2009","journal-title":"Pharmacol. Rep."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464817303844?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464817303844?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T12:57:01Z","timestamp":1659185821000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464817303844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12]]},"references-count":31,"alternative-id":["S1050464817303844"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2017.06.061","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification and characterization of the lamprey Flotillin-1 gene with a role in cell adhesion","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2017.06.061","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}