{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:28:53Z","timestamp":1787164133667,"version":"build-2736575974"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"China Agriculture Research System","award":["CARS-47"],"award-info":[{"award-number":["CARS-47"]}]},{"name":"Guangdong Province Special Funds for Innovation and Development of Marine Economy Demonstration Area","award":["2014Y200169"],"award-info":[{"award-number":["2014Y200169"]}]},{"name":"Project of Benefits of Agricultural Science and Technology (Guangdong Finance Agriculture","award":["585"],"award-info":[{"award-number":["585"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.fsi.2017.08.009","type":"journal-article","created":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T21:01:17Z","timestamp":1502744477000},"page":"85-89","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["l -amino acid oxidase expression profile and biochemical responses of rabbitfish ( Siganus oramin ) after exposure to a high dose of Cryptocaryon irritans"],"prefix":"10.1016","volume":"69","author":[{"given":"Biao","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng-Li","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge-Ling","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Wei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An-Xing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2017.08.009_bib1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1023\/A:1018360323287","article-title":"Cryptocaryon irritans Brown 1951, the cause of \u2018white spot disease\u2019 in marine fish: an update","volume":"1","author":"Colomi","year":"1997","journal-title":"Aquar. Sci. Conserv."},{"key":"10.1016\/j.fsi.2017.08.009_bib2","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0932-4739(11)80405-0","article-title":"Ultrastructural features of Cryptocaryon irritans, a ciliate parasite of marine fish","volume":"29","author":"Colorni","year":"1993","journal-title":"Eur. J. Protistol."},{"key":"10.1016\/j.fsi.2017.08.009_bib3","first-page":"97","article-title":"Enzootics in the New York aquarium caused by Cryptocaryon irritans Brown, 1951 (=Ichthyophthirius marinuss Sikama, 1961), a histophagous ciliate in the skin, eyes and gills of marine fishes","volume":"51","author":"Nigrelli","year":"1966","journal-title":"Zoologica"},{"key":"10.1016\/j.fsi.2017.08.009_bib4","first-page":"227","article-title":"Outbreak of cryptocaryoniasis in marine aquaria at scripps institution of oceanography","volume":"55","author":"Wilkie","year":"1969","journal-title":"Calif. Fish. Game"},{"key":"10.1016\/j.fsi.2017.08.009_bib5","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1007\/s00436-008-0904-9","article-title":"Some characteristics of host-parasite relationship for Cryptocaryon irritans isolated from South China","volume":"102","author":"Luo","year":"2008","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.fsi.2017.08.009_bib6","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/0044-8486(87)90041-X","article-title":"Biology of Cryptocaryon irritans and strategies for its control","volume":"67","author":"Colorni","year":"1987","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2017.08.009_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0044-8486(03)00167-4","article-title":"Killing effect of various treatments on the monogenean Heterobothrium okamotoi eggs and oncomiracidia and the ciliate Cryptocaryon irritans cysts and theronts","volume":"223","author":"Hirazawa","year":"2003","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2017.08.009_bib8","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.aquaculture.2016.03.028","article-title":"Placemat and rotational culturing: a novel method to control Cryptocaryon irritans infection by removing tomonts","volume":"459","author":"Jiang","year":"2016","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2017.08.009_bib9","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0044-8486(01)00503-8","article-title":"Antiparasitic effect of medium-chain fatty acids against the ciliate Cryptocaryon irritans infestation in the red sea bream Pagrus major","volume":"198","author":"Hirazawa","year":"2001","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2017.08.009_bib10","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.aquaculture.2014.09.007","article-title":"Antiparasitic effects of Sophora flavescens root extracts on the ciliate, Cryptocaryon irritans","volume":"435","author":"Goto","year":"2015","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2017.08.009_bib11","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.fsi.2006.04.011","article-title":"Protective immunity in grouper (Epinephelus coioides) following exposure to or injection with Cryptocaryon irritans","volume":"22","author":"Luo","year":"2007","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2017.08.009_bib12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3147\/jsfp.32.229","article-title":"Acquired protection and production of immobilization antibody against Cryptocaryon irritans (Ciliophora, Hymenostomatida) in mummichog (Fundulus heteroclitus)","volume":"32","author":"Yoshinaga","year":"1997","journal-title":"Fish. Pathol."},{"key":"10.1016\/j.fsi.2017.08.009_bib13","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.exppara.2015.04.010","article-title":"Immunological, ionic and biochemical responses in blood serum of the marine fish Trachinotus ovatus to poly-infection by Cryptocaryon irritans","volume":"154","author":"Yin","year":"2015","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.fsi.2017.08.009_bib14","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0959-8030(96)90008-3","article-title":"Immune response of fishes to ciliates","volume":"6","author":"Dickerson","year":"1996","journal-title":"Ann. Rev. Fish. Dis."},{"key":"10.1016\/j.fsi.2017.08.009_bib15","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.fsi.2010.01.006","article-title":"A\u00a0novel protein isolated from the serum of rabbitfish (Siganus oramin) is lethal to Cryptocaryon irritans","volume":"29","author":"Wang","year":"2010","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2017.08.009_bib16","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/j.fsi.2011.02.004","article-title":"The serum of rabbitfish (Siganus oramin) has antimicrobial activity to some pathogenic organisms and a novel serum L-amino acid oxidase is isolated","volume":"30","author":"Wang","year":"2011","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2017.08.009_bib17","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1016\/j.fsi.2013.09.026","article-title":"Siganus oramin recombinant L-amino acid oxidase is lethal to Cryptocaryon irritans","volume":"35","author":"Li","year":"2013","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2017.08.009_bib18","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.aquaculture.2006.04.026","article-title":"A\u00a0standardized method to propagate Cryptocaryon irritans on a susceptible host pompano Trachinotus ovatus","volume":"258","author":"Dan","year":"2006","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2017.08.009_bib19","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(delta delta C (T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2017.08.009_bib20","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1017\/S0031182013001613","article-title":"Effects of Cryptocaryon irritans infection on the survival, feeding, respiratory rate and ionic regulation of the marbled rockfish Sebastiscus marmoratus","volume":"141","author":"Yin","year":"2014","journal-title":"Parasitology"},{"key":"10.1016\/j.fsi.2017.08.009_bib21","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A\u00a0rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem"},{"key":"10.1016\/j.fsi.2017.08.009_bib22","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.fsi.2013.11.019","article-title":"Growth, feed intake and immune responses of orange-spotted grouper (Epinephelus coioides) exposed to low infectious doses of ectoparasite (Cryptocaryon irritans)","volume":"36","author":"Yin","year":"2014","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2017.08.009_bib23","doi-asserted-by":"crossref","first-page":"7847","DOI":"10.1007\/s00253-015-6844-2","article-title":"Antibacterial properties of L-amino acid oxidase: mechanisms of action and perspectives for therapeutic applications","volume":"99","author":"Kasai","year":"2015","journal-title":"Appl. Microbiol. Biot."},{"key":"10.1016\/j.fsi.2017.08.009_bib24","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1016\/S0021-9258(18)69355-X","article-title":"Crystalline L-amino acid oxidase of Crotalus adamanteus","volume":"235","author":"Wellner","year":"1960","journal-title":"J.\u00a0Biol. Chem."},{"issue":"6","key":"10.1016\/j.fsi.2017.08.009_bib25","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/sj.cdd.4401385","article-title":"Hydrogen peroxide produced by Aplysia ink toxin kills tumor cells independent of apoptosis via peroxiredoxin I sensitive pathways","volume":"11","author":"Butzke","year":"2004","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.fsi.2017.08.009_bib26","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00251-010-0482-8","article-title":"Origin and diversification of the L-amino oxidase family in innate immune defenses of animals","volume":"62","author":"Hughes","year":"2010","journal-title":"Immunogenetics"},{"key":"10.1016\/j.fsi.2017.08.009_bib27","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cbpb.2009.05.006","article-title":"Isolation and cDNA cloning of an antibacterial L-amino acid oxidase from the skin mucus of the great sculpin Myoxocephalus polyacanthocephalus","volume":"154","author":"Nagashima","year":"2009","journal-title":"Comp. Biochem. Phys. b"},{"key":"10.1016\/j.fsi.2017.08.009_bib28","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.cbpb.2010.08.006","article-title":"Discovery of serum L-amino acid oxidase in the rockfish Sebastes schlegeli: isolation and biochemical characterization","volume":"157","author":"Kitani","year":"2010","journal-title":"Comp. Biochem. Phys. b"},{"key":"10.1016\/j.fsi.2017.08.009_bib29","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1742-4658.2009.07497.x","article-title":"Novel L-amino acid oxidase with antibacterial activity against methicillin-resistant Staphylococcus aureus isolated from epidermal mucus of the flounder Platichthys stellatus","volume":"277","author":"Kasai","year":"2010","journal-title":"FEBS J."},{"key":"10.1016\/j.fsi.2017.08.009_bib30","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1007\/s11033-015-3930-6","article-title":"Cloning and characterization of the gene for L-amino acid oxidase in hybrid tilapia","volume":"42","author":"Shen","year":"2015","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.fsi.2017.08.009_bib31","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.ijbiomac.2015.05.053","article-title":"Sources of marine superoxide dismutases: characteristics and applications","volume":"79","author":"Zeinali","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.fsi.2017.08.009_bib32","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/j.fsi.2012.01.026","article-title":"New insights in flat oyster Ostrea edulis resistance against the parasite Bonamia ostreae","volume":"32","author":"Morga","year":"2012","journal-title":"Fish. Shellfish Immunol."},{"key":"10.1016\/j.fsi.2017.08.009_bib33","first-page":"682","article-title":"Stress and immune responses of the marbled rockfish Sebastiscus marmoretus infected with Cryptocaryon irritans","volume":"38","author":"Yin","year":"2014","journal-title":"Acta Hydrobiol. Sin."},{"key":"10.1016\/j.fsi.2017.08.009_bib34","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.cbpb.2004.04.005","article-title":"Expression and distribution of Na, K-ATPase in gill and kidney of the spotted green pufferfish, Tetraodon nigroviridis, in response to salinity challenge","volume":"138","author":"Lin","year":"2004","journal-title":"Comp. Biochem. Phys. A"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464817304709?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464817304709?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T01:31:59Z","timestamp":1659317519000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464817304709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":34,"alternative-id":["S1050464817304709"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2017.08.009","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"l-amino acid oxidase expression profile and biochemical responses of rabbitfish (Siganus oramin) after exposure to a high dose of Cryptocaryon irritans","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2017.08.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}