{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:31:58Z","timestamp":1763037118185,"version":"3.37.3"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31402335","31572651","31572656","U1401211"],"award-info":[{"award-number":["31402335","31572651","31572656","U1401211"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2015A030308020"],"award-info":[{"award-number":["2015A030308020"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Projects of Department of Education of Guangdong Province","award":["2014GKXM046","2013gjhz0008","2015KCXTD021","2013CXZDA019"],"award-info":[{"award-number":["2014GKXM046","2013gjhz0008","2015KCXTD021","2013CXZDA019"]}]},{"DOI":"10.13039\/501100007162","name":"Projects of Guangdong Province Department of Science and Technology","doi-asserted-by":"publisher","award":["2016B020201009","2013B090700010"],"award-info":[{"award-number":["2016B020201009","2013B090700010"]}],"id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.fsi.2017.09.058","type":"journal-article","created":{"date-parts":[[2017,9,23]],"date-time":"2017-09-23T23:30:55Z","timestamp":1506209455000},"page":"665-672","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Identification and characterization of CD40 from humphead snapper (Lutjanus sanguineus)"],"prefix":"10.1016","volume":"70","author":[{"given":"Jia","family":"Cai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunxia","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongli","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yishan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jichang","family":"Jian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaohe","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2017.09.058_bib1","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/jlb.67.1.2","article-title":"CD40-CD40 ligand","volume":"67","author":"Van Kooten","year":"2000","journal-title":"J.\u00a0Leukoc. Biol."},{"key":"10.1016\/j.fsi.2017.09.058_bib2","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1056\/NEJM199109053251010","article-title":"Primary hepatocellular carcinoma","volume":"325","author":"Wands","year":"1991","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.fsi.2017.09.058_bib3","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1084\/jem.168.1.157","article-title":"Isolation and characterization of human tonsil dendritic cells","volume":"168","author":"Hart","year":"1988","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.fsi.2017.09.058_bib4","doi-asserted-by":"crossref","first-page":"775","DOI":"10.4049\/jimmunol.149.3.775","article-title":"CD40 is functionally expressed on human thymic epithelial cells","volume":"149","author":"Galy","year":"1992","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib5","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.1073\/pnas.92.10.4342","article-title":"CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression","volume":"92","author":"Karmann","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.fsi.2017.09.058_bib6","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/0090-1229(95)90135-3","article-title":"CD40 expression by human fibroblasts","volume":"77","author":"Fries","year":"1995","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1016\/j.fsi.2017.09.058_bib7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000236923","article-title":"CD40 ligand\/CD40 deficiency","volume":"107","author":"Castigli","year":"1995","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib8","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S0952-7915(97)80078-7","article-title":"Functions of CD40 on B cells, dendritic cells and other cells","volume":"9","author":"Kooten","year":"1997","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib9","first-page":"231","article-title":"Increased expression of CD40 on thymocytes and peripheral T cells in autoimmunity: a mechanism for acquiring changes in the peripheral T cell receptor repertoire","volume":"4","author":"Wagner","year":"1999","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.fsi.2017.09.058_bib10","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/PL00000776","article-title":"The CD40\/CD154 receptor\/ligand dyad","volume":"58","author":"Sch\u00f6nbeck","year":"2001","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.fsi.2017.09.058_bib11","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/0167-5699(96)10060-I","article-title":"The many roles of CD40 in cell-mediated inflammatory responses","volume":"17","author":"Stout","year":"1996","journal-title":"Immunol. Today"},{"key":"10.1016\/j.fsi.2017.09.058_bib12","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0065-2776(08)60854-8","article-title":"CD40 and its ligand","volume":"63","author":"Foy","year":"1996","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib13","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1159\/000237614","article-title":"Functional role of CD40 and its ligand","volume":"113","author":"Van Kooten","year":"1997","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib14","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1146\/annurev.iy.12.040194.004313","article-title":"The CD40 antigen and its ligand","volume":"12","author":"Banchereau","year":"1994","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib15","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S0952-7915(97)80078-7","article-title":"Functions of CD40 on B cells, dendritic cells and other cells","volume":"9","author":"Kooten","year":"1997","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib16","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/1074-7613(94)90095-7","article-title":"The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation","volume":"1","author":"Kawabe","year":"1994","journal-title":"Immunity"},{"key":"10.1016\/j.fsi.2017.09.058_bib17","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1084\/jem.180.5.1889","article-title":"Humoral immune responses in CD40 ligand-deficient mice","volume":"180","author":"Renshaw","year":"1994","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.fsi.2017.09.058_bib18","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1126\/science.281.5373.96","article-title":"Visualization of specific B and T lymphocyte interactions in the lymph node","volume":"281","author":"Garside","year":"1998","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.fsi.2017.09.058_bib19","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S1074-7613(00)80408-2","article-title":"CD40 and its ligand in host defense","volume":"4","author":"Noelle","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/j.fsi.2017.09.058_bib20","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/978-0-387-70630-6_11","article-title":"TRAF proteins in CD40 signaling","volume":"597","author":"Bishop","year":"2007","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.fsi.2017.09.058_bib21","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1002\/j.1460-2075.1989.tb03521.x","article-title":"B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas","volume":"8","author":"Stamenkovic","year":"1989","journal-title":"EMBO J."},{"key":"10.1016\/j.fsi.2017.09.058_bib22","doi-asserted-by":"crossref","first-page":"3873","DOI":"10.4049\/jimmunol.143.12.3873","article-title":"Activation of human B cells. Comparison of the signal transduced by IL-4 to four different competence signals","volume":"143","author":"Clark","year":"1989","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib23","doi-asserted-by":"crossref","first-page":"4917","DOI":"10.4049\/jimmunol.155.10.4917","article-title":"Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes","volume":"155","author":"Kiener","year":"1995","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib24","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1007\/s00251-005-0032-y","article-title":"Characterization and expression of a CD40 homolog gene in Japanese flounder Paralichthys olivaceus","volume":"57","author":"Park","year":"2005","journal-title":"Immunogenetics"},{"key":"10.1016\/j.fsi.2017.09.058_bib25","doi-asserted-by":"crossref","first-page":"7749","DOI":"10.4049\/jimmunol.0804370","article-title":"CD154-CD40 interactions are essential for thymus-dependent antibody production in zebrafish: insights into the origin of costimulatory pathway in helper T cell-regulated adaptive immunity in early vertebrates","volume":"182","author":"Gong","year":"2009","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib26","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.dci.2012.07.011","article-title":"CD40L-a costimulatory molecule involved in the maturation of antigen presenting cells in Atlantic salmon (Salmo salar)","volume":"38","author":"Lagos","year":"2012","journal-title":"Dev. Comp. Immunol."},{"issue":"7","key":"10.1016\/j.fsi.2017.09.058_bib27","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.molimm.2005.06.040","article-title":"Two interleukin (IL)-15 homologues in fish from two distinct origins","volume":"43","author":"Bei","year":"2006","journal-title":"Mol. Immunol."},{"issue":"12","key":"10.1016\/j.fsi.2017.09.058_bib28","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1105\/tpc.12.12.2367","article-title":"Mutations in the FIE and MEA genes that encode interacting polycomb proteins cause parent-of-origin effects on seed development by distinct mechanisms","volume":"12","author":"Yadegari","year":"2000","journal-title":"Plant Cell"},{"key":"10.1016\/j.fsi.2017.09.058_bib29","doi-asserted-by":"crossref","first-page":"10168","DOI":"10.1021\/bi9909905","article-title":"High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization","volume":"38","author":"Pullen","year":"1999","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.fsi.2017.09.058_bib30","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1084\/jem.180.1.141","article-title":"Memory B cell development but not germinal center formation is impaired by in\u00a0vivo blockade of CD40-CD40 ligand interaction","volume":"180","author":"Gray","year":"1994","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.fsi.2017.09.058_bib31","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1146\/annurev.immunol.22.012703.104533","article-title":"CD40\/CD154 interactions at the interface of tolerance and immunity","volume":"22","author":"Quezada","year":"2004","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib32","doi-asserted-by":"crossref","first-page":"11226","DOI":"10.1074\/jbc.M110.208215","article-title":"Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation","volume":"286","author":"An","year":"2011","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fsi.2017.09.058_bib33","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.dci.2012.07.011","article-title":"CD40L-a costimulatory molecule involved in the maturation of antigen presenting cells in Atlantic salmon (Salmo salar)","volume":"38","author":"Lagos","year":"2012","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2017.09.058_bib34","doi-asserted-by":"crossref","unstructured":"Engel D, Seijkens T, Poggi M, Sanati M, Thevissen L, Beckers L, et\u00a0al. The immunobiology of CD154-CD40-TRAF interactions in atherosclerosis. Semin. Immunol.;21(5):308\u2013312.","DOI":"10.1016\/j.smim.2009.06.004"},{"key":"10.1016\/j.fsi.2017.09.058_bib35","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/978-0-387-70630-6_11","article-title":"TRAF proteins inCD40 signaling","volume":"597","author":"Bishop","year":"2007","journal-title":"Adv. Exp. Med. Biol."},{"issue":"2","key":"10.1016\/j.fsi.2017.09.058_bib36","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.fsi.2015.06.021","article-title":"Identification and characterization of tumor necrosis factor receptor (TNFR)-associated factor 3 from humphead snapper, Lutjanus sanguineus","volume":"46","author":"Cai","year":"2015","journal-title":"Fish. Shellfish Immunol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464817305776?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464817305776?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,26]],"date-time":"2023-08-26T09:01:58Z","timestamp":1693040518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464817305776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":36,"alternative-id":["S1050464817305776"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2017.09.058","relation":{},"ISSN":["1050-4648"],"issn-type":[{"type":"print","value":"1050-4648"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification and characterization of CD40 from humphead snapper (Lutjanus sanguineus)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2017.09.058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}