{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:19:06Z","timestamp":1777375146303,"version":"3.51.4"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Open Project Program of the Key Laboratory of Mariculturre & Enhancement of Zhejiang Province","award":["2016KF003"],"award-info":[{"award-number":["2016KF003"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["41606150"],"award-info":[{"award-number":["41606150"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.fsi.2017.12.041","type":"journal-article","created":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T08:37:17Z","timestamp":1514536637000},"page":"84-93","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Molecular characterization and expression analysis of large yellow croaker (Larimichthys crocea) interleukin-12A, 16 and 34 after poly I:C and Vibrio anguillarum challenge"],"prefix":"10.1016","volume":"74","author":[{"given":"Luping","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihua","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changwen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bao","family":"Lou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2017.12.041_bib1","first-page":"277","article-title":"Fish immune system. A crossroads between innate and adaptive responses","volume":"22","author":"Tort JCB","year":"2003","journal-title":"Inmunologia"},{"key":"10.1016\/j.fsi.2017.12.041_bib2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nri1001","article-title":"Interleukin-12 and the regulation of innate resistance and adaptive immunity","volume":"3","author":"Trinchieri","year":"2003","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib3","first-page":"133","article-title":"Molecular characterization of an IL-1\u03b2 gene from the large yellow croaker (Larimichthys crocea) and its effect on fish defense against Vibrio alginolyticus infection","volume":"36","author":"Jun Wu","year":"2015","journal-title":"Dong Wu Xue Yan Jiu"},{"key":"10.1016\/j.fsi.2017.12.041_bib4","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.fsi.2017.10.009","article-title":"Identification of a single p19 gene and three p40 paralogues in grass carp (Ctenopharyngodon idellus): their potential for the formation of interleukin 23 and inducible expression in vitro and in vivo","volume":"71","author":"Wang","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.dci.2014.03.008","article-title":"The IL-1 family in fish: swimming through the muddy waters of inflammasome evolution","volume":"46","author":"Ogryzko","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1146\/annurev.iy.13.040195.001343","article-title":"Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity","volume":"13","author":"Trinchieri","year":"1995","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib7","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/0167-5699(96)10052-I","article-title":"Interleukin 16 and its function as a CD4 ligand","volume":"17","author":"Center","year":"1996","journal-title":"Immunol. Today"},{"key":"10.1016\/j.fsi.2017.12.041_bib8","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1093\/rheumatology\/kes435","article-title":"IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14(bright)CD16+ monocytes","volume":"52","author":"Ciccia","year":"2013","journal-title":"Rheumatology"},{"key":"10.1016\/j.fsi.2017.12.041_bib9","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.fsi.2004.09.006","article-title":"Innate immunity of fish (overview)","volume":"20","author":"Magnadottir","year":"2006","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib10","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/ni.2366","article-title":"IL-12 family cytokines: immunological playmakers","volume":"13","author":"Vignali","year":"2012","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib11","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1084\/jem.170.3.827","article-title":"Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes","volume":"170","author":"Kobayashi","year":"1989","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.fsi.2017.12.041_bib12","first-page":"4437","article-title":"Development of TH1 CD4+ T cells through IL-12 produced by Listeria-Induced macrophages","volume":"181","author":"Hsieh SEM","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib13","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1084\/jem.177.4.1199","article-title":"Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells","volume":"177","author":"Manetti","year":"1993","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.fsi.2017.12.041_bib14","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.4049\/jimmunol.128.6.2563","article-title":"Modulation of lymphocyte migration by human lymphokines. I. Identification and characterization of chemoattractant activity for lymphocytes from mitogen-stimulated mononuclear cells","volume":"128","author":"Center","year":"1982","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaci.2010.11.050","article-title":"Interleukins, from 1 to 37, and interferon-gamma: receptors, functions, and roles in diseases","volume":"127","author":"Akdis","year":"2011","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib16","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1074\/jbc.273.2.1144","article-title":"Processing and activation of pro-interleukin-16 by caspase-3","volume":"273","author":"Zhang","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fsi.2017.12.041_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1182\/blood-2005-03-1312","article-title":"Human and mouse mast cells use the tetraspanin CD9 as an alternate interleukin-16 receptor","volume":"107","author":"Qi","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.fsi.2017.12.041_bib18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/jcp.24441","article-title":"Regulation of cellular processes by interleukin-16 in homeostasis and cancer","volume":"229","author":"Richmond","year":"2014","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.fsi.2017.12.041_bib19","doi-asserted-by":"crossref","first-page":"993","DOI":"10.2174\/1381612013397591","article-title":"Cytokine and chemokine based control of HIV infection and replication","volume":"7","author":"Alfano","year":"2001","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.fsi.2017.12.041_bib20","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1086\/314550","article-title":"Interleukin-16 (IL-16) inhibits human immunodeficiency virus replication in cells from infected subjects, and serum IL-16 levels drop with disease progression","volume":"179","author":"Amiel","year":"1999","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.fsi.2017.12.041_bib21","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1126\/science.1154370","article-title":"Discovery of a cytokine and its receptor by functional screening of the extracellular proteome","volume":"320","author":"Lin","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.fsi.2017.12.041_bib22","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1136\/annrheumdis-2011-200096","article-title":"Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients","volume":"71","author":"Chemel","year":"2012","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.fsi.2017.12.041_bib23","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/1754-9485.12249","article-title":"Magnetic resonance imaging aspects of giant-cell tumours of bone","volume":"58","author":"Pereira","year":"2014","journal-title":"J. Med. Imag. Radiat. Oncol."},{"key":"10.1016\/j.fsi.2017.12.041_bib24","article-title":"The critical role of IL-34 in osteoclastogenesis","volume":"6","author":"Chen","year":"2011","journal-title":"PLos One"},{"key":"10.1016\/j.fsi.2017.12.041_bib25","article-title":"Association of IL12A expression quantitative trait loci (eQTL) with primary biliary cirrhosis in a Chinese han population","volume":"95","author":"Li","year":"2016","journal-title":"Medicine"},{"key":"10.1016\/j.fsi.2017.12.041_bib26","doi-asserted-by":"crossref","first-page":"249","DOI":"10.5603\/GP.a2017.0047","article-title":"IL16 and IL18 gene polymorphisms in women with gestational diabetes","volume":"88","author":"Tarnowski","year":"2017","journal-title":"Ginekol. Pol."},{"key":"10.1016\/j.fsi.2017.12.041_bib27","doi-asserted-by":"crossref","first-page":"6030","DOI":"10.1158\/0008-5472.CAN-16-1170","article-title":"Chemotherapy-induced IL34 enhances immunosuppression by tumor-associated macrophages and mediates survival of chemoresistant lung cancer cells","volume":"76","author":"Baghdadi","year":"2016","journal-title":"Canc. Res."},{"key":"10.1016\/j.fsi.2017.12.041_bib28","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.4238\/2015.February.6.20","article-title":"Differential expression of interleukin-12 p35 and p40 subunits in response to Aeromonas hydrophila and Aquareovirus infection in grass carp, Ctenopharyngodon idella","volume":"14","author":"Pandit","year":"2015","journal-title":"Genet. Mol. Res. : GMR"},{"key":"10.1016\/j.fsi.2017.12.041_bib29","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.cbpb.2006.02.012","article-title":"Cloning, characterization and expression analysis of two Tetraodon nigroviridis interleukin-16 isoform genes","volume":"144","author":"Wen","year":"2006","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.fsi.2017.12.041_bib30","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.molimm.2012.09.008","article-title":"Identification of IL-34 in teleost fish: differential expression of rainbow trout IL-34, MCSF1 and MCSF2, ligands of the MCSF receptor","volume":"53","author":"Wang","year":"2013","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2017.12.041_bib31","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1467-2979.2008.00278.x","article-title":"Profile of a fishery collapse: why mariculture failed to save the large yellow croaker","volume":"9","author":"Liu","year":"2008","journal-title":"Fish Fish."},{"key":"10.1016\/j.fsi.2017.12.041_bib32","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1128\/AEM.70.4.2089-2097.2004","article-title":"Influence of environmental factors and human activity on the presence of Salmonella serovars in a marine environment","volume":"70","author":"Martinez-Urtaza","year":"2004","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.fsi.2017.12.041_bib33","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1365-2761.2011.01279.x","article-title":"Vibrio anguillarum as a fish pathogen: virulence factors, diagnosis and prevention","volume":"34","author":"Frans","year":"2011","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2017.12.041_bib34","doi-asserted-by":"crossref","first-page":"R759","DOI":"10.1152\/ajpregu.00293.2004","article-title":"The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism","volume":"287","author":"Fortier","year":"2004","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.fsi.2017.12.041_bib35","doi-asserted-by":"crossref","first-page":"5227","DOI":"10.1038\/ncomms6227","article-title":"The draft genome of the large yellow croaker reveals well-developed innate immunity","volume":"5","author":"Wu","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.fsi.2017.12.041_bib36","doi-asserted-by":"crossref","first-page":"W320","DOI":"10.1093\/nar\/gku316","article-title":"Deciphering key features in protein structures with the new ENDscript server","volume":"42","author":"Robert","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.fsi.2017.12.041_bib37","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2017.12.041_bib38","article-title":"Prediction of protein structure and the principles of protein conformation","volume":"247","author":"Fasman","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.fsi.2017.12.041_bib39","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1110\/ps.34701","article-title":"Role for cysteine residues in the in vivo folding and assembly of the phage P22 tailspike","volume":"10","author":"Haase-Pettingell","year":"2001","journal-title":"Protein Sci."},{"key":"10.1016\/j.fsi.2017.12.041_bib40","doi-asserted-by":"crossref","first-page":"24682","DOI":"10.1074\/jbc.270.42.24682","article-title":"A disulfide bond between conserved extracellular cysteines in the thyrotropin-releasing hormone receptor is critical for binding","volume":"270","author":"Perlman WW","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fsi.2017.12.041_bib41","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S1367-5931(99)00021-6","article-title":"Effect of N-linked glycosylation on glycopeptide and glycoprotein structure","volume":"3","author":"Imperiali SEOC","year":"1999","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.fsi.2017.12.041_bib42","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1002\/prot.22509","article-title":"Increasing protein stability by improving beta-turns","volume":"77","author":"Fu","year":"2009","journal-title":"Proteins"},{"key":"10.1016\/j.fsi.2017.12.041_bib43","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1242\/jcs.114.18.3219","article-title":"Mechanism and role of PDZ domains in signaling complex assembly","volume":"114","author":"Baruch","year":"2001","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.fsi.2017.12.041_bib44","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.bbapap.2012.04.012","article-title":"The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1","volume":"1824","author":"Liu","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.fsi.2017.12.041_bib45","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2761.1996.tb00128.x","article-title":"Retention of furunculosis vaccine components in Atlantic salmon, Salmo salar L., following different routes of vaccine administration","volume":"19","author":"Press","year":"1996","journal-title":"J. Fish. Dis."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464817307829?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464817307829?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T08:30:15Z","timestamp":1693384215000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464817307829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":45,"alternative-id":["S1050464817307829"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2017.12.041","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular characterization and expression analysis of large yellow croaker (Larimichthys crocea) interleukin-12A, 16 and 34 after poly I:C and Vibrio anguillarum challenge","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2017.12.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}