{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T04:26:25Z","timestamp":1768796785948,"version":"3.49.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province","doi-asserted-by":"publisher","award":["LH2019C028"],"award-info":[{"award-number":["LH2019C028"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012657","name":"\u201cYoung Talents\u201d Project of Northeast Agricultural University","doi-asserted-by":"publisher","award":["18QC38"],"award-info":[{"award-number":["18QC38"]}],"id":[{"id":"10.13039\/501100012657","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["31372568"],"award-info":[{"award-number":["31372568"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["31511130137"],"award-info":[{"award-number":["31511130137"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.fsi.2020.03.001","type":"journal-article","created":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T19:46:49Z","timestamp":1583264809000},"page":"18-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Oral immunization with recombinant Lactobacillus casei displayed AHA1-CK6 and VP2 induces protection against infectious pancreatic necrosis in rainbow trout (Oncorhynchus mykiss)"],"prefix":"10.1016","volume":"100","author":[{"given":"Yaping","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojing","family":"Hua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuanyu","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kexin","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinhui","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dechuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiahui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiawei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2020.03.001_bib1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1128\/jvi.21.1.242-258.1977","article-title":"Virus-specific protein synthesis in cells infected by infectious pancreatic necrosis Virus","volume":"21","author":"Dobos","year":"1977","journal-title":"J. Virol."},{"key":"10.1016\/j.fsi.2020.03.001_bib2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1139\/m83-062","article-title":"The molecular biology of infectious pancreatic necrosis virus: a review","volume":"29","author":"Dobos","year":"1983","journal-title":"Can. J. Microbiol."},{"key":"10.1016\/j.fsi.2020.03.001_bib3","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1099\/0022-1317-76-5-1165","article-title":"Mapping of neutralization epitopes on infectious pancreatic necrosis viruses","volume":"76","author":"Frost","year":"1995","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.fsi.2020.03.001_bib4","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1089\/vim.2007.0043","article-title":"EImmunogenicity properties of authentic and heterologously synthesized structural protein VP2 of infectious pancreatic necrosis virus","volume":"20","author":"Fridholm","year":"2007","journal-title":"Viral Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib5","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0959-8030(95)00003-8","article-title":"The molecular biology of infectious pancreatic necrosis virus (IPNV)","volume":"5","author":"Dobos","year":"1995","journal-title":"Annu. Rev. Fish Dis."},{"key":"10.1016\/j.fsi.2020.03.001_bib6","series-title":"Infectious Pancreatic Necrosis Virus","first-page":"83","author":"Evensen","year":"2008"},{"key":"10.1016\/j.fsi.2020.03.001_bib7","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0959-8030(95)00011-9","article-title":"Serological classification of infectious pancreatic necrosis (IPN) virus and other aquatic birnaviruses","volume":"5","author":"Hill","year":"1995","journal-title":"Annu. Rev. Fish Dis."},{"key":"10.1016\/j.fsi.2020.03.001_bib8","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0065-3527(03)62003-8","article-title":"Infectious pancreatic necrosis virus: biology, pathogenesis, and diagnostic methods","volume":"62","author":"Rodriguez","year":"2003","journal-title":"Adv. Virus Res."},{"key":"10.1016\/j.fsi.2020.03.001_bib9","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.dci.2016.03.024","article-title":"Oral vaccination of fish: lessons from humans and veterinary species","volume":"64","author":"Embregts","year":"2016","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib10","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.fsi.2012.03.016","article-title":"Oral immunization of rainbow trout to infectious pancreatic necrosis virus (IPNV) induces different immune gene expression profiles in head kidney and pyloric ceca","volume":"33","author":"Ballesteros","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib11","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.dci.2017.05.004","article-title":"Oral DNA vaccines based on CS-TPP nanoparticles and alginate microparticles confer high protection against infectious pancreatic necrosis virus (IPNV) infection in trout","volume":"74","author":"Ahmadivand","year":"2017","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib12","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1016\/S0264-410X(02)00229-3","article-title":"Recombinant Lactobacillus johnsonii as a mucosal vaccine delivery vehicle","volume":"20","author":"Scheppler","year":"2002","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2020.03.001_bib13","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.fsi.2011.11.015","article-title":"Immunogenicity of Lactobacillus-expressing VP2 and VP3 of the infectious pancreatic necrosis virus (IPNV) in rainbow trout","volume":"32","author":"Liu","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib14","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1016\/j.vaccine.2011.12.132","article-title":"Expression of infectious pancreatic necrosis virus (IPNV) VP2eVP3 fusion protein in Lactobacillus casei and immunogenicity in rainbow trouts","volume":"30","author":"Zhao","year":"2012","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2020.03.001_bib15","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s00253-010-3050-0","article-title":"Lactobacillus acidophilus as a live vehicle for oral immunization against chicken anemia virus","volume":"90","author":"Moeini","year":"2011","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.fsi.2020.03.001_bib16","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/jam.13446","article-title":"Lactic acid bacteria-promising vaccine vectors: possibilities, limitations, doubts","volume":"123","author":"Szatraj","year":"2017","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.fsi.2020.03.001_bib17","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.it.2013.01.005","article-title":"Regulation of intestinal homeostasis and immunity with probiotic lactobacilli","volume":"34","author":"Van","year":"2013","journal-title":"Trends Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib18","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.fsi.2018.09.034","article-title":"Oral immunization with a recombinant Lactobacillus expressing CK6 fused with VP2 protein against IPNV in rainbow trout (Oncorhynchus mykiss)","volume":"83","author":"Duan","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib19","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.fsi.2003.10.003","article-title":"Cloning, characterisation and expression of Aeromonas hydrophila major adhesin","volume":"16","author":"Fang","year":"2004","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib20","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.vetimm.2012.07.013","article-title":"Evaluation of two outer membrane proteins, Aha1 and OmpW of Aeromonas hydrophila as vaccine candidate for common carp","volume":"149","author":"Maiti","year":"2012","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.fsi.2020.03.001_bib21","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.dci.2011.03.011","article-title":"Chemokines in teleost fish species","volume":"35","author":"Al\u00ed","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib22","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.dci.2008.05.004","article-title":"Interleukin 8 and CK-6 chemokines specifically attract rainbow trout (Oncorhynchus mykiss) RTS11 monocyte\u2013macrophage cells and have variable effects on their immune functions","volume":"32","author":"Montero","year":"2008","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib23","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.dci.2006.12.008","article-title":"Expression of inducible CC chemokines in rainbow trout (Oncorhynchus mykiss) in response to a viral haemorrhagic septicemia virus (VHSV) DNA vaccine and interleukin 8","volume":"31","author":"Sanchez","year":"2007","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib24","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0378-1135(01)00355-8","article-title":"Antigenicproperties and experimental transmission to several fish species of a marine birnavirus isolated from sole (Solea senegalensis)","volume":"82","author":"Perezprieto","year":"2001","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.fsi.2020.03.001_bib25","doi-asserted-by":"crossref","first-page":"8301","DOI":"10.1007\/s00253-014-5893-2","article-title":"Up-regulation of MDP and tuftsin gene expression in Th1 and Th17 cells as an adjuvant for an oral Lactobacillus casei vaccine against anti-transmissible gastroenteritis virus","volume":"98","year":"2014","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.fsi.2020.03.001_bib26","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/jam.13352","article-title":"Immunogenicity of recombinant Lactobacillus casei-expressing F4 (K88) fimbrial adhesin FaeG in conjunction with a heat-labile enterotoxin A (LTAK63) and heat-labile enterotoxin B (LTB) of enterotoxigenic Escherichia coli as an oral adjuvant in mice","volume":"122","author":"Yu","year":"2017","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.fsi.2020.03.001_bib27","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1128\/AEM.00127-15","article-title":"Immunogenicity in swine of orally administered recombinant Lactobacillus plantarum expressing classical swine fever virus E2 protein in conjunction with thymosin alpha-1 as an adjuvant","volume":"81","author":"Xu","year":"2015","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.fsi.2020.03.001_bib28","doi-asserted-by":"crossref","first-page":"5908","DOI":"10.1016\/j.biomaterials.2014.03.077","article-title":"The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3","volume":"35","author":"Qin","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.fsi.2020.03.001_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0033196","article-title":"Functional identification of dendritic cells in the teleost model, rainbow trout (Oncorhynchus mykiss)","volume":"7","author":"Bassity","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.fsi.2020.03.001_bib30","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.jviromet.2007.09.003","article-title":"Detection and quantitation of infectious pancreatic necrosis virus by real-time reverse transcriptase-polymerase chain reaction using lethal and non-lethal tissue sampling","volume":"147","author":"Bowers","year":"2008","journal-title":"J. Virol Methods"},{"key":"10.1016\/j.fsi.2020.03.001_bib31","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.fsi.2014.01.001","article-title":"Comparative skin mucus and serum humoral defence mechanisms in the teleost gilthead seabream (sparus aurata)","volume":"36","author":"Guardiola","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib32","first-page":"493","article-title":"A simple method of estimating ffty percent endpoint","volume":"27","author":"Reed","year":"1938","journal-title":"Am. J. Hyg."},{"key":"10.1016\/j.fsi.2020.03.001_bib33","first-page":"72","article-title":"Finfish in aquaculture and their diseases-A retrospective view on the European Community","volume":"22","author":"Ariel","year":"2002","journal-title":"Bull. Eur. Assoc. Fish Pathol."},{"key":"10.1016\/j.fsi.2020.03.001_bib34","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.2147\/DDDT.S171087","article-title":"Discovery of nonnucleoside inhibitors of polymerase from infectious pancreatic necrosis virus (ipnv)","volume":"12","author":"Melissa","year":"2018","journal-title":"Drug Des. Dev. Ther."},{"issue":"3","key":"10.1016\/j.fsi.2020.03.001_bib35","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1046\/j.1365-2567.1999.00791.x","article-title":"Ileal and jejunal Peyer's patches play distinct roles in mucosal immunity of sheep","volume":"97","author":"Mutwiri","year":"2010","journal-title":"Immunology"},{"issue":"2","key":"10.1016\/j.fsi.2020.03.001_bib36","article-title":"In vitro and in vivo immune responses induced by a dna vaccine encoding the vp2 gene of the infectious pancreatic necrosis virus","volume":"27","author":"Heras","year":"2009","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib37","doi-asserted-by":"crossref","first-page":"3291","DOI":"10.1016\/j.vaccine.2010.02.106","article-title":"An active DNA vaccine against infectious pancreatic necrosis virus (IPNV) with a different mode of action than fish rhabdovirus DNA vaccines","volume":"28","author":"Cuesta","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2020.03.001_bib38","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0044-8486(72)90045-2","article-title":"Antibody production in the plaice (Pleuronectes platessa L.) after oral and parenteral immunization with Vibrio anguillarum antigens","volume":"1","author":"Fletcher","year":"1972","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2020.03.001_bib39","doi-asserted-by":"crossref","first-page":"87","DOI":"10.4049\/jimmunol.44.1.87","article-title":"The oral immunization of trout against bacterium salmonicida","volume":"44","author":"Duff","year":"1942","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2020.03.001_bib40","doi-asserted-by":"crossref","first-page":"525","DOI":"10.3390\/biology4030525","article-title":"The mucosal immune system of teleost fish","volume":"4","author":"Salinas","year":"2015","journal-title":"Biology"},{"issue":"Suppl 1","key":"10.1016\/j.fsi.2020.03.001_bib41","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1016\/j.ijfoodmicro.2009.12.024","article-title":"Lactic acid bacteria efficiently protect human and animal intestinal epithelial and immune cells from enteric virus infection","volume":"141","author":"Maragkoudakis","year":"2010","journal-title":"Int. J. Food Microbiol."},{"key":"10.1016\/j.fsi.2020.03.001_bib42","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.archoralbio.2011.10.006","article-title":"Isolation and characterization of probiotic strains for improving oral health","volume":"57","author":"Bosch","year":"2012","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.fsi.2020.03.001_bib43","doi-asserted-by":"crossref","first-page":"4010","DOI":"10.1016\/j.vaccine.2017.05.076","article-title":"Recombinant Lactobacillus casei, expressing Clostridium perfringens, toxoids \u0251, \u03b22, \u03b5 and \u03b21 gives protection against Clostridium perfringens in rabbits","volume":"35","author":"Li","year":"2017","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2020.03.001_bib44","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.dci.2009.06.008","article-title":"Immune effects observed after the injection of plasmids coding for rainbow trout (Oncorhynchus mykiss) CK5B, CK6 and CK7A chemokines demonstrate their immunomodulatory capacity and reveal CK6 as a major interferon inducer","volume":"33","author":"Montero","year":"2009","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib45","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.dci.2006.12.008","article-title":"Expression of inducible CC chemokines in rainbow trout (Oncorhynchus mykiss) in response to a viral haemorrhagic septicemia virus (VHSV) DNA vaccine and Interleukin 8","volume":"31","author":"Sanchez","year":"2007","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib46","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1089\/10799900050023906","article-title":"Chemokine gene adjuvants can modulate immune responses induced by DNA vaccines","volume":"20","author":"Kim","year":"2000","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.fsi.2020.03.001_bib47","doi-asserted-by":"crossref","first-page":"8729","DOI":"10.1128\/JVI.77.16.8729-8735.2003","article-title":"Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines","volume":"77","author":"Barouch","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.fsi.2020.03.001_bib48","series-title":"Effect and Mechanism of PCSK6 on Rheumatoid Arthritis and Collagen-Induced Arthritis Fibroblast-like Synoviocytes, Master's Thesis","author":"Jiang","year":"2015"},{"issue":"4","key":"10.1016\/j.fsi.2020.03.001_bib49","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1111\/j.1365-2672.2012.05399.x","article-title":"Changes in adhesion ability of aeromonas hydrophila during long exposure to salt stress conditions","volume":"113","author":"Pianetti","year":"2012","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.fsi.2020.03.001_bib50","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1365-3083.2008.02201.x","article-title":"Differential expression of immune genes in Atlantic salmon (Salmo salar L.) challenged intraperitoneally or by cohabitation with IPNV","volume":"69","author":"Ingerslev","year":"2009","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib51","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.dci.2013.08.017","article-title":"Innate immune responses of salmonid fish to viral infections","volume":"43","author":"Collet","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.03.001_bib52","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1146\/annurev.biochem.67.1.227","article-title":"How cells respond to interferons","volume":"67","author":"Stark","year":"1998","journal-title":"Annu. Rev. Biochem."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464820301595?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464820301595?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T05:15:17Z","timestamp":1760937317000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464820301595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":52,"alternative-id":["S1050464820301595"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2020.03.001","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oral immunization with recombinant Lactobacillus casei displayed AHA1-CK6 and VP2 induces protection against infectious pancreatic necrosis in rainbow trout (Oncorhynchus mykiss)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2020.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}