{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:25:16Z","timestamp":1791516316963,"version":"4.3.4"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T00:00:00Z","timestamp":1623715200000},"content-version":"am","delay-in-days":287,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1755348"],"award-info":[{"award-number":["1755348"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["2DN70-2RDN7"],"award-info":[{"award-number":["2DN70-2RDN7"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish &amp; Shellfish Immunology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.fsi.2020.05.076","type":"journal-article","created":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T11:32:48Z","timestamp":1591011168000},"page":"165-171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["Fish nasal immunity: From mucosal vaccines to neuroimmunology"],"prefix":"10.1016","volume":"104","author":[{"given":"Pankoj Kumar","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Salinas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2020.05.076_bib1","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.isci.2019.08.034","article-title":"Convergent evolution of mucosal immune responses at the buccal cavity of teleost fish","volume":"19","author":"Yu","year":"2019","journal-title":"iScience"},{"issue":"11","key":"10.1016\/j.fsi.2020.05.076_bib2","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.4049\/jimmunol.1900863","article-title":"Pharyngeal immunity in early vertebrates provides functional and evolutionary insight into mucosal homeostasis","volume":"203","author":"Kong","year":"2019","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2020.05.076_bib3","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.7808","article-title":"An update on anatomy and function of the teleost olfactory system","volume":"7","author":"Olivares","year":"2019","journal-title":"PeerJ"},{"issue":"7","key":"10.1016\/j.fsi.2020.05.076_bib4","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.3390\/ijms20071639","article-title":"The olfactory system of zebrafish as a model for the study of neurotoxicity and injury: implications for neuroplasticity and disease","volume":"20","author":"Calvo-Ochoa","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"3\u20135","key":"10.1016\/j.fsi.2020.05.076_bib5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s11068-005-8353-1","article-title":"Diversity in the olfactory epithelium of bony fishes: development, lamellar arrangement, sensory neuron cell types and transduction components","volume":"34","author":"Hansen","year":"2005","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.fsi.2020.05.076_bib6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.molimm.2015.09.008","article-title":"The evolution of nasal immune systems in vertebrates","volume":"69","author":"Sepahi","year":"2016","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2020.05.076_bib7","doi-asserted-by":"crossref","first-page":"9328","DOI":"10.1523\/JNEUROSCI.23-28-09328.2003","article-title":"Correlation between olfactory receptor cell type and function in the channel catfish","volume":"23","author":"Hansen","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.fsi.2020.05.076_bib8","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s10886-013-0268-1","article-title":"Properties, projections, and tuning of teleost olfactory receptor neurons","volume":"39","author":"Baz\u00e1es","year":"2013","journal-title":"J. Chem. Ecol."},{"key":"10.1016\/j.fsi.2020.05.076_bib9","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1038\/srep02063","article-title":"Zebrafish crypt neurons project to a single, identified mediodorsal glomerulus","volume":"24","author":"Ahuja","year":"2013","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fsi.2020.05.076_bib10","doi-asserted-by":"crossref","first-page":"4037","DOI":"10.1038\/srep04037","article-title":"Kappe neurons, a novel population of olfactory sensory neurons","volume":"4","author":"Ahuja","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fsi.2020.05.076_bib11","doi-asserted-by":"crossref","first-page":"7808","DOI":"10.7717\/peerj.7808","article-title":"An update on anatomy and function of the teleost olfactory system","volume":"7","author":"Olivares","year":"2019","journal-title":"PeerJ"},{"issue":"25","key":"10.1016\/j.fsi.2020.05.076_bib12","doi-asserted-by":"crossref","first-page":"12428","DOI":"10.1073\/pnas.1900083116","article-title":"Olfactory sensory neurons mediate ultrarapid antiviral immune responses in a TrkA-dependent manner","volume":"116","author":"Sepahi","year":"2019","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib13","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms6205","article-title":"Nasal immunity is an ancient arm of the mucosal immune system of vertebrates","volume":"5","author":"Tacchi","year":"2014","journal-title":"Nat. Commun."},{"issue":"8","key":"10.1016\/j.fsi.2020.05.076_bib14","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1093\/chemse\/bjz050","article-title":"Commensal bacteria regulate gene expression and differentiation in vertebrate olfactory systems through transcription factor REST","volume":"44","author":"Casadei E","year":"2019","journal-title":"Chem. Senses"},{"issue":"6","key":"10.1016\/j.fsi.2020.05.076_bib15","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.vaccine.2014.12.055","article-title":"Evaluation of dual nasal delivery of infectious hematopoietic necrosis virus and enteric red mouth vaccines in rainbow trout (Oncorhynchus mykiss)","volume":"33","author":"LaPatra","year":"2015","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib16","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.dci.2015.05.015","article-title":"Nasal vaccination of young rainbow trout (Oncorhynchus mykiss) against infectious hematopoietic necrosis and enteric red mouth disease","volume":"53","author":"Salinas","year":"2015","journal-title":"Dev. Comp. Immunol."},{"issue":"11","key":"10.1016\/j.fsi.2020.05.076_bib17","doi-asserted-by":"crossref","first-page":"3900","DOI":"10.4049\/jimmunol.1700757","article-title":"CK12a, a CCL19-like chemokine that orchestrates both nasal and systemic antiviral immune responses in rainbow trout,","volume":"199","author":"Sepahi","year":"2017","journal-title":"J. Immunol."},{"issue":"11","key":"10.1016\/j.fsi.2020.05.076_bib18","doi-asserted-by":"crossref","first-page":"4453","DOI":"10.4049\/jimmunol.1600678","article-title":"Tissue microenvironments in the nasal epithelium of rainbow trout (Oncorhynchus mykiss) define two distinct CD8\u03b1+ cell populations and establish regional immunity","volume":"197","author":"Sepahi","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2020.05.076_bib19","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.fsi.2016.01.006","article-title":"An attenuated virus vaccine appears safe to the central nervous system of rainbow trout (Oncorhynchus mykiss) after intranasal delivery","volume":"49","author":"Larragoite","year":"2016","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.05.076_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.ppat.1007251","article-title":"Mucosal immunoglobulins protect the olfactory organ of teleost fish against parasitic infection","volume":"14","author":"Yu","year":"2018","journal-title":"PLoS Pathog."},{"issue":"6","key":"10.1016\/j.fsi.2020.05.076_bib21","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.4049\/jimmunol.1900157","article-title":"Nasal vaccination drives modifications of nasal and systemic antibody repertoires in rainbow trout","volume":"203","author":"Magadan","year":"2019","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2020.05.076_bib22","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1577\/1548-8667(1994)006<0101:OOOCCA>2.3.CO;2","article-title":"Olfactory organ of channel catfish as a site of experimental Edwardsiella ictaluri infection","volume":"6","author":"Morrison","year":"1994","journal-title":"J. Aquat. Anim. Health"},{"issue":"4","key":"10.1016\/j.fsi.2020.05.076_bib23","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1365-2761.1989.tb00322.x","article-title":"Pathology of experimental enteric septicaemia in channel catfish, Ictalurus punctatus (Rafinesque), following immersion-exposure to Edwardsiella ictaluri","volume":"12","author":"Newton","year":"1989","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2020.05.076_bib24","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0044-8486(00)00376-8","article-title":"Experimental Streptococcus iniae infection of hybrid striped bass (Morone chrysops_Morone saxatilis) and tilapia (Oreochromis niloticus) by nares inoculation","volume":"189","author":"Evans","year":"2000","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2020.05.076_bib25","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0044-8486(00)00522-6","article-title":"Distribution of Streptococcus iniae in hybrid striped bass (Morone chrysops_Morone saxatilis) following nare inoculation","volume":"194","author":"Evans","year":"2001","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2020.05.076_bib26","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0044-8486(02)00633-6","article-title":"Streptococcus iniae infection and tissue distribution in hybrid striped bass (Morone chrysops_Morone saxatilis) following inoculation of the gills","volume":"220","author":"McNulty","year":"2003","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2020.05.076_bib27","series-title":"Health Maintenance and Principal Microbial Diseases of Cultured Fishes","author":"Plumb","year":"2010"},{"issue":"7","key":"10.1016\/j.fsi.2020.05.076_bib28","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.1128\/JVI.80.7.3655-3659.2006","article-title":"Bioluminescence Imaging of live infected salmonids reveals that the fin bases are the major portal of entryfor Novirhabdoviruses","volume":"80","author":"Harmache","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.fsi.2020.05.076_bib29","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.virusres.2016.12.013","article-title":"Infectious hematopoietic necrosis virus (IHNV) outbreak in farmed rainbow trout in Iran: viral isolation, pathological findings, molecular confirmation, and genetic analysis","volume":"229","author":"Ahmadivand","year":"2017","journal-title":"Virus Res."},{"issue":"5\u20136","key":"10.1016\/j.fsi.2020.05.076_bib30","first-page":"433","article-title":"Characterization of IHNV isolates associated with neurotropism","volume":"26","author":"LaPatra","year":"1995","journal-title":"Vet. Res."},{"key":"10.1016\/j.fsi.2020.05.076_bib31","series-title":"Fish Diseases and Disorders","first-page":"66","article-title":"Infectious hematopoietic necrosis virus","volume":"vol. 3","author":"Bootland","year":"2012"},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib32","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3354\/dao032015","article-title":"Viral hemorrhagic septicemia virus, Ichthyophonus hoferi, and other causes of morbidity in Pacific herring Clupea pallasi spawning in Prince William Sound, Alaska, USA","volume":"32","author":"Marty","year":"1998","journal-title":"Dis. Aquat. Org."},{"issue":"7","key":"10.1016\/j.fsi.2020.05.076_bib33","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1365-2761.2004.00559.x","article-title":"Histopathological studies on viral nervous necrosis of sevenband grouper, Epinephelus septemfasciatus Thunberg, at the grow-out stage","volume":"27","author":"Tanaka","year":"2004","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2020.05.076_bib34","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3354\/dao032173","article-title":"Replication and pathogenesis of white sturgeon iridovirus (WSIV) in experimentally infected white sturgeon Acipenser transmontanus juveniles and sturgeon cell lines","volume":"32","author":"Watson","year":"1998","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2020.05.076_bib35","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3354\/dao030017","article-title":"Fatal encephalitis due to the scuticociliate Uronema nigricans in sea-caged, southern bluefin tuna Thunnus maccoyii","volume":"30","author":"Munday","year":"1997","journal-title":"Dis. Aquat. Org."},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib36","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1645\/GE-3256RN","article-title":"Occurrence of Ergasilus megaceros Wilson, 1916, in the sea lamprey and other fishes from North America","volume":"90","author":"Muzzall","year":"2004","journal-title":"J. Parasitol."},{"issue":"3","key":"10.1016\/j.fsi.2020.05.076_bib37","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/jfd.12754","article-title":"Experimental infection by Yersinia ruckeri O1 biotype 2 induces brain lesions and neurological signs in rainbow trout (Oncorhynchus mykiss)","volume":"41","author":"Str\u00f8m","year":"2018","journal-title":"J. Fish. Dis."},{"issue":"2","key":"10.1016\/j.fsi.2020.05.076_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0089672","article-title":"3D visualization of the initial Yersinia ruckeri infection route in rainbow trout (Oncorhynchus mykiss) by optical projection tomography","volume":"9","author":"Ohtani","year":"2014","journal-title":"PloS One"},{"issue":"4","key":"10.1016\/j.fsi.2020.05.076_bib39","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1577\/H03-026.1","article-title":"Isolation of Edwardsiella ictaluri from tadpole madtom in a southwestern New Jersey river","volume":"15","author":"Klesius","year":"2003","journal-title":"J. Aquat. Anim. Health"},{"issue":"3","key":"10.1016\/j.fsi.2020.05.076_bib40","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1577\/1548-8667(1994)006<0234:DOEIIC>2.3.CO;2","article-title":"Distribution of Edwardsiella ictaluri in California","volume":"6","author":"Chen","year":"1994","journal-title":"J. Aquat. Anim. Health"},{"key":"10.1016\/j.fsi.2020.05.076_bib41","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.dci.2018.11.022","article-title":"Comparative models for human nasal infections and immunity","volume":"92","author":"Casadei E","year":"2019","journal-title":"Dev. Comp. Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib42","first-page":"1","article-title":"Mucosal immunoglobulins at respiratory surfaces mark an ancient association that predates the emergence of tetrapods","volume":"7","author":"Xu","year":"2016","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.fsi.2020.05.076_bib43","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1038\/mi.2014.135","article-title":"Phenotype and function of nasal dendritic cells","volume":"8","author":"Lee","year":"2015","journal-title":"Mucosal Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib44","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1042\/bj20031253","article-title":"Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis","volume":"377","author":"Rejman","year":"2004","journal-title":"Biochem. J."},{"issue":"20","key":"10.1016\/j.fsi.2020.05.076_bib45","doi-asserted-by":"crossref","first-page":"18021","DOI":"10.1074\/jbc.M111257200","article-title":"Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis","volume":"277","author":"Zuhorn","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fsi.2020.05.076_bib46","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1091\/mbc.10.4.961","article-title":"Extraction of cholesterol with methyl-\u03b2-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles","volume":"1094","author":"Rodal","year":"1999","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.fsi.2020.05.076_bib47","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.3389\/fimmu.2019.01499","article-title":"M cells: intelligent engineering of mucosal immune surveillance","volume":"10","author":"Dillon","year":"2019","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.fsi.2020.05.076_bib48","doi-asserted-by":"crossref","first-page":"2884\u201090","DOI":"10.1128\/IAI.67.6.2884-2890.1999","article-title":"Antibody responses in the lower respiratory tract and male urogenital tract in humans after nasal and oral vaccination with cholera toxin B subunit","volume":"67","author":"Rudin","year":"1999","journal-title":"Infect. Immun."},{"issue":"9","key":"10.1016\/j.fsi.2020.05.076_bib49","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.4161\/hv.25458","article-title":"Intranasal vaccination with an inactivated whole influenza virus vaccine induces strong antibody responses in serum and nasal mucus of healthy adults","volume":"9","author":"Ainai","year":"2013","journal-title":"Hum. Vaccines Immunother."},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib50","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/infdis\/jis641","article-title":"Localized mucosal response to intranasal live attenuated influenza vaccine in adults","volume":"207","author":"Barr\u00eda","year":"2013","journal-title":"J. Infect. Dis."},{"issue":"5","key":"10.1016\/j.fsi.2020.05.076_bib51","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1093\/infdis\/135.5.697","article-title":"Formation of secretory and circulating antibodies after immunization with live and inactivated influenza virus vaccines","volume":"135","author":"Shvartsman","year":"1977","journal-title":"J. Infect. Dis."},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib52","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/1742-2094-9-155","article-title":"Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases","volume":"9","author":"Tian","year":"2012","journal-title":"J. Neuroinflammation"},{"issue":"4","key":"10.1016\/j.fsi.2020.05.076_bib53","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1172\/JCI58644","article-title":"Innate immunity in the central nervous system","volume":"122","author":"Ransohoff","year":"2012","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.fsi.2020.05.076_bib54","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.cell.2014.04.050","article-title":"Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility","volume":"158","author":"Muller","year":"2014","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.fsi.2020.05.076_bib55","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.it.2016.10.001","article-title":"Nociceptor sensory neuron\u2013immune interactions in pain and inflammation","volume":"38","author":"Pinho-Ribeiro","year":"2017","journal-title":"Trends Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2020.05.076_bib56","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.jpain.2010.08.003","article-title":"Interleukin-17 contributes to neuroinflammation and neuropathic pain following peripheral nerve injury in mice","volume":"12","author":"Kim","year":"2011","journal-title":"J. Pain"},{"issue":"11","key":"10.1016\/j.fsi.2020.05.076_bib57","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1038\/cr.2014.106","article-title":"Nociceptive neurons regulate innate and adaptive immunity and neuropathic pain through MyD88 adapter","volume":"24","author":"Liu","year":"2014","journal-title":"Cell Res."},{"issue":"5","key":"10.1016\/j.fsi.2020.05.076_bib58","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/nm.3852","article-title":"The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell\u2013derived leukocyte elastase","volume":"21","author":"Vicu\u00f1a","year":"2015","journal-title":"Nat. Med."},{"issue":"11","key":"10.1016\/j.fsi.2020.05.076_bib59","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1182\/blood-2013-04-498105","article-title":"Mast cell activation contributes to sickle cell pathobiology and pain in mice","volume":"122","author":"Vincent","year":"2013","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.fsi.2020.05.076_bib60","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1021\/acschemneuro.6b00043","article-title":"The olfactory bulb: an immunosensory effector organ during neurotropic viral infections","volume":"7","author":"Durrant","year":"2016","journal-title":"ACS Chem. Neurosci."}],"container-title":["Fish &amp; Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464820304022?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464820304022?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T11:09:17Z","timestamp":1778584157000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464820304022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":60,"alternative-id":["S1050464820304022"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2020.05.076","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fish nasal immunity: From mucosal vaccines to neuroimmunology","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2020.05.076","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}