{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T16:39:36Z","timestamp":1780677576286,"version":"3.54.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"publisher","award":["2019JM-035"],"award-info":[{"award-number":["2019JM-035"]}],"id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007548","name":"Northwest A and F University","doi-asserted-by":"publisher","award":["2452018029"],"award-info":[{"award-number":["2452018029"]}],"id":[{"id":"10.13039\/501100007548","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.fsi.2020.06.021","type":"journal-article","created":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T02:26:50Z","timestamp":1591756010000},"page":"262-268","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Surface display of spring viremia of carp virus glycoprotein on Lactococcus lactis and its protection efficacy in common carp (Cyprinus carpio L.)"],"prefix":"10.1016","volume":"104","author":[{"given":"Chen","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Rao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gao-Xue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2020.06.021_bib1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3354\/dao052261","article-title":"Spring viremia of carp (SVC)","volume":"52","author":"Ahne","year":"2002","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2020.06.021_bib2","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1007\/s00705-007-0971-8","article-title":"Characterization of complete genome sequence of the spring viremia of carp virus isolated from common carp (Cyprinus carpio) in China","volume":"152","author":"Teng","year":"2007","journal-title":"Arch. Virol."},{"key":"10.1016\/j.fsi.2020.06.021_bib3","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3354\/dao076193","article-title":"Phylogenetic analysis of spring virema of carp virus reveals distinct subgroups with common origins for recent isolates in North America and the UK","volume":"76","author":"Miller","year":"2007","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2020.06.021_bib4","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1099\/jgv.0.000436","article-title":"Spring viraemia of carp virus: recent advances","volume":"97","author":"Ashraf","year":"2016","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.fsi.2020.06.021_bib5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.fsi.2017.05.021","article-title":"Immunogenicity and efficacy of DNA vaccine encoding antigenic AcfA via addition of the molecular adjuvant Myd88 against Vibrio alginolyticus in Epinephelus coioides","volume":"66","author":"Huang","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib6","doi-asserted-by":"crossref","first-page":"6415","DOI":"10.1016\/j.vaccine.2008.08.071","article-title":"DNA vaccine protects ornamental koi (Cyprinus carpio koi) against North American spring viremia of carp virus","volume":"26","author":"Emmenegger","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2020.06.021_bib7","doi-asserted-by":"crossref","first-page":"4927","DOI":"10.1016\/j.vaccine.2006.03.062","article-title":"DNA vaccination can protect Cyprinus Carpio against spring viraemia of carp virus","volume":"24","author":"Kanellos","year":"2006","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2020.06.021_bib8","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0167-7799(02)00006-9","article-title":"Microbial cell-surface display","volume":"21","author":"Lee","year":"2003","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.fsi.2020.06.021_bib9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/nbt0197-29","article-title":"Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines","volume":"15","author":"Georgious","year":"1997","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.fsi.2020.06.021_bib10","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/76494","article-title":"Surface-displayed viral antigens on Salmonella carrier vaccine","volume":"18","author":"Lee","year":"2000","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.fsi.2020.06.021_bib11","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1128\/IAI.01037-09","article-title":"A foreign protein incorporated on the Tip of T3 pili in Lactococcus lactis elicits systemic and mucosal immunity","volume":"78","author":"Quigley","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fsi.2020.06.021_bib12","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1128\/CVI.00050-11","article-title":"Evaluation of oral immunization with recombinant avian influenza virus HA1 displayed on the Lactococcus lactis surface and combined with the mucosal adjuvant cholera toxin subunit B","volume":"18","author":"Lei","year":"2011","journal-title":"Clin. Vaccine Immunol."},{"issue":"5483","key":"10.1016\/j.fsi.2020.06.021_bib13","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1126\/science.289.5483.1352","article-title":"Treatment of murine colitis by Lactococcus lactis secreting interleukin-10","volume":"289","author":"Steidler","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.fsi.2020.06.021_bib14","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1080\/21505594.2019.1653720","article-title":"An EGFP-marked recombinant lactobacillus oral tetravalent vaccine constitutively expressing \u03b1, \u03b5, \u03b21, and \u03b22 toxoids for Clostridium perfringens elicits effective anti-toxins protective immunity","volume":"10","author":"Ding","year":"2019","journal-title":"Virulence"},{"key":"10.1016\/j.fsi.2020.06.021_bib15","doi-asserted-by":"crossref","first-page":"575","DOI":"10.3390\/v11060575","article-title":"Dendritic cell targeting of bovine viral diarrhea virus E2 protein expressed by Lactobacillus casei effectively induces antigen-specific immune responses via oral vaccination","volume":"11","author":"Wang","year":"2019","journal-title":"Viruses"},{"key":"10.1016\/j.fsi.2020.06.021_bib16","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12934-018-0861-7","article-title":"Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of porcine epidemic diarrhea virus","volume":"17","author":"Ma","year":"2018","journal-title":"Microb. Cell Factories"},{"key":"10.1016\/j.fsi.2020.06.021_bib17","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3390\/vaccines8010017","article-title":"Protection efficacy of oral bait probiotic vaccine constitutively expressing tetravalent toxoids against Clostridium perfringens exotoxins in livestock (rabbits)","volume":"8","author":"Bai","year":"2020","journal-title":"Vaccines"},{"key":"10.1016\/j.fsi.2020.06.021_bib18","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3390\/v9110312","article-title":"Oral delivery of probiotics expressing dendritic cell-targeting peptide fused with porcine epidemic diarrhea virus COE antigen: a promising vaccine strategy against PEDV","volume":"9","author":"Wang","year":"2017","journal-title":"Viruses"},{"key":"10.1016\/j.fsi.2020.06.021_bib19","doi-asserted-by":"crossref","first-page":"29172923","DOI":"10.1128\/AEM.68.6.2917-2923.2002","article-title":"Lactococcus lactis is a powerful carrier for cell wall-associated and secreted bovine beta-lactoglobulin fusion proteins","volume":"68","author":"Bernasconi","year":"2002","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.fsi.2020.06.021_bib20","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00253-010-2849-z","article-title":"Use of the usp45 lactococcal secretion signal sequence to drive the secretion and functional expression of enterococcal bacteriocins in Lactococcus lactis","volume":"89","author":"Borrero","year":"2011","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.fsi.2020.06.021_bib21","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/j.1348-0421.2008.00050.x","article-title":"Nasal administration of Lactococcus lactis improves local and systemic immune responses against Streptococcus pneumoniae","volume":"52","author":"Medina","year":"2008","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib22","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1128\/IAI.00119-08","article-title":"Nasal immunization with Lactococcus lactis expressing the pneumococcal protective protein A induces protective immunity in mice","volume":"76","author":"Medina","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fsi.2020.06.021_bib23","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1111\/j.1365-2672.2010.04757.x","article-title":"Immobilization of Lactococcus lactis to cellulosic material by cellulose-binding domain of Cellvibrio japonicus","volume":"109","author":"Kyla-Nikkila","year":"2010","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.fsi.2020.06.021_bib24","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1111\/j.1472-765X.2010.02950.x","article-title":"Surface display of respiratory syncytial virus glycoproteins inLactococcus lactis NZ9000","volume":"5","author":"Lim","year":"2010","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.fsi.2020.06.021_bib25","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.fsi.2017.10.060","article-title":"Display of GCRV vp& protein on the surface of Escherichia coli and its immunoprotective effects in grass carp (Ctenopharyngodon idella)","volume":"72","author":"Hao","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib26","doi-asserted-by":"crossref","first-page":"6334","DOI":"10.1016\/j.vaccine.2018.08.003","article-title":"Enhanced protective immunity against spring viremia of carp virus infection can be induced by recombinant subunit vaccine conjugated to single-walled carbon nanotubes","volume":"36","author":"Zhang","year":"2018","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2020.06.021_bib27","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12951-020-0584-x","article-title":"Application of antigen presenting cell-targeted nanovaccine delivery system in rhabdovirus disease prophylactics using fish as a model organism","volume":"18","author":"Zhang","year":"2020","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.fsi.2020.06.021_bib28","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2017.01340","article-title":"Intramuscular DNA vaccination of juvenile carp against spring viremia of carp virus induces full protection and establishes a virus-specific B and T cell response","volume":"8","author":"Embregts","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib29","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.fsi.2018.05.029","article-title":"Immune response and protective effect against spring viremia of carp virus induced by intramuscular vaccination with a SWCNTs-DNA vaccine encoding matrix protein","volume":"79","author":"Zhang","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib30","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.foodres.2017.10.067","article-title":"Effect of free and microencapsulated Lactococcus lactis on composition and rheological properties of Manchego-type cheeses during ripening","volume":"105","author":"Salazarmontoya","year":"2018","journal-title":"Food Res. Int."},{"key":"10.1016\/j.fsi.2020.06.021_bib31","first-page":"134","article-title":"Production of recombinant protein of salsola kali (Sal k1) pollen allergen in Lactococcus Lactis. Iran","volume":"17","author":"Ghasemi","year":"2018","journal-title":"J. Allergy Asthma"},{"key":"10.1016\/j.fsi.2020.06.021_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00253-017-8579-8","article-title":"Nisin-induced expression of recombinant T cell epitopes of major Japanese cedar pollen allergens in Lactococcus lactis","volume":"102","author":"Van Hoang","year":"2018","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.fsi.2020.06.021_bib33","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12896-019-0518-6","article-title":"Mucosal delivery of Lactococcus lactis carrying an anti-TNF scFv expression vector ameliorates experimental colitis in mice","volume":"19","author":"Maria Jos\u00e9","year":"2019","journal-title":"BMC Biotechnol."},{"key":"10.1016\/j.fsi.2020.06.021_bib34","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.1016\/j.vaccine.2015.05.002","article-title":"Recombinant lactobacillus expressing G protein of spring viremia of carp virus (SVCV) combined with ORF81 protein of koi herpesvirus (KHV): a promising way to induce protective immunity against SVCV and KHV infection in cyprinid fish via oral vaccination","volume":"33","author":"Cui","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.fsi.2020.06.021_bib35","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1586\/14760584.5.6.803","article-title":"Optimization and delivery of plasmid DNA for vaccination","volume":"5","author":"Jechlinger","year":"2014","journal-title":"Expert Rev. Vaccines"},{"key":"10.1016\/j.fsi.2020.06.021_bib36","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/j.dci.2011.03.007","article-title":"Advances in fish vaccine delivery","volume":"35","author":"Plant","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib37","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.fsi.2016.07.004","article-title":"Optimization of efficacy of a live attenuated Flavobacterium psychrophilum immersion vaccine","volume":"56","author":"Sudheesh","year":"2016","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib38","doi-asserted-by":"crossref","first-page":"550","DOI":"10.3389\/fimmu.2014.00550","article-title":"The humoral immune response to HCV: understanding is key to vaccine development","volume":"5","author":"Cashman","year":"2014","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib39","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.fsi.2017.03.030","article-title":"Oral delivery of, Bacillus subtilis spores expressing cysteine protease of Clonorchis sinensis to grass carp (Ctenopharyngodon idellus): induces immune responses and has no damage on liver and intestine function","volume":"64","author":"Tang","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2020.06.021_bib40","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/j.fsi.2013.10.015","article-title":"The teleost humoral immune response","volume":"35","author":"Ye","year":"2013","journal-title":"Fish Shellfish Immunol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464820304435?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464820304435?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T21:57:04Z","timestamp":1778795824000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464820304435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":40,"alternative-id":["S1050464820304435"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2020.06.021","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Surface display of spring viremia of carp virus glycoprotein on Lactococcus lactis and its protection efficacy in common carp (Cyprinus carpio L.)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2020.06.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}