{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T10:40:12Z","timestamp":1763116812757,"version":"build-2065373602"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordination of Higher Education Personnel Improvement","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.fsi.2021.05.004","type":"journal-article","created":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T22:52:51Z","timestamp":1620341571000},"page":"12-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Effects of triploid induction on innate immunity and hematology in Astyanax altiparanae"],"prefix":"10.1016","volume":"116","author":[{"given":"Nycolas","family":"Levy-Pereira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mateus Maldonado","family":"Carriero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George Shigueki","family":"Yasui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6976-3194","authenticated-orcid":false,"given":"Caroline Munhoz","family":"Meira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Luiz Moro","family":"de Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Augusto Mendes","family":"Maia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Augusto","family":"Senhorini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana","family":"Pilarski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"year":"2018","series-title":"The State of World Fisheries and Aquaculture 2018 - Meeting the Sustainable Development Goals","author":"FAO","key":"10.1016\/j.fsi.2021.05.004_bib1"},{"year":"2016","series-title":"The State of World Fisheries and Aquaculture. Contributing to food security and nutrition for all","author":"FAO","key":"10.1016\/j.fsi.2021.05.004_bib2"},{"key":"10.1016\/j.fsi.2021.05.004_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/S0044-8486(01)00588-9","article-title":"Genetic improvement of aquaculture finfish species by chromosome manipulation techniques in Japan","author":"Arai","year":"2001","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2021.05.004_bib4","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.aquaculture.2009.04.036","article-title":"Polyploid fish and shellfish: production, biology and applications to aquaculture for performance improvement and genetic containment","volume":"293","author":"Piferrer","year":"2009","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2021.05.004_bib5","doi-asserted-by":"crossref","DOI":"10.1007\/s10530-016-1066-9","article-title":"Genetic screening of farmed Atlantic salmon escapees demonstrates that triploid fish display reduced migration to freshwater","author":"Glover","year":"2016","journal-title":"Biol. Invasions"},{"key":"10.1016\/j.fsi.2021.05.004_bib6","doi-asserted-by":"crossref","DOI":"10.1111\/are.13952","article-title":"Added value from an added chromosome: potential of producing large fillet fish from autumn to spring with triploid rainbow trout, Oncorhynchus mykiss","author":"Janhunen","year":"2019","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.fsi.2021.05.004_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/0044-8486(87)90351-6","article-title":"Early survival rates and subsequent morphological abnormalities in landlocked, anadromous and hybrid (landlocked \u00d7 anadromous) diploid and triploid Atlantic salmon","author":"Sutterlin","year":"1987","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2021.05.004_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/S0044-8486(01)00508-7","article-title":"High prevalence of skeletal deformity and reduced gill surface area in triploid Atlantic salmon (Salmo salar L.)","author":"Sadler","year":"2001","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2021.05.004_bib9","article-title":"Concurrence of lower jaw skeletal anomalies in triploid Atlantic salmon (Salmo salar L.) and the effect on growth in freshwater","author":"Amoroso","year":"2016","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2021.05.004_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbd.2016.05.001","article-title":"Proteomic analysis of skeletal deformity in diploid and triploid rainbow trout (Oncorhynchus mykiss) larvae","author":"Babaheydari","year":"2016","journal-title":"Comp. Biochem. Physiol. Genom. Proteonomics"},{"key":"10.1016\/j.fsi.2021.05.004_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2013.09.034","article-title":"The effect of triploidy on the culture performance, deformity prevalence, and heart morphology in Atlantic salmon","author":"Fraser","year":"2013","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2021.05.004_bib12","doi-asserted-by":"crossref","DOI":"10.1186\/1746-6148-7-71","article-title":"The culturable intestinal microbiota of triploid and diploid juvenile Atlantic salmon (Salmo salar) - a comparison of composition and drug resistance","author":"Cantas","year":"2011","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.fsi.2021.05.004_bib13","doi-asserted-by":"crossref","DOI":"10.3354\/dao02242","article-title":"High Gyrodactylus salaris infection rate in triploid Atlantic salmon Salmo salar","author":"Ozerov","year":"2010","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2021.05.004_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2013.06.014","article-title":"Comparison of disease resistance between diploid, induced-triploid, and intercross-triploid rainbow trout including trout selected for resistance to Flavobacterium psychrophilum","author":"Weber","year":"2013","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2021.05.004_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/S0044-8486(99)00314-2","article-title":"Acute stress response in triploid rainbow trout (Oncorhynchus mykiss) and brook trout (Salvelinus fontinalis)","author":"Benfey","year":"2000","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2021.05.004_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2016.08.018","article-title":"Performance of triploid Atlantic cod (Gadus morhua L.) in commercial aquaculture","author":"Otter\u00e5","year":"2016","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2021.05.004_bib17","doi-asserted-by":"crossref","DOI":"10.1006\/fsim.2000.0319","article-title":"The kinetics of the hypoferraemic response and changes in levels of alternative complement activity in diploid and triploid Atlantic salmon, following injection of lipopolysaccharide","author":"Langston","year":"2001","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2021.05.004_bib18","doi-asserted-by":"crossref","DOI":"10.1046\/j.1095-8649.2003.00194.x","article-title":"Disease resistance, stress response and effects of triploidy in growth hormone transgenic coho salmon","author":"Jhingan","year":"2003","journal-title":"J. Fish. Biol."},{"key":"10.1016\/j.fsi.2021.05.004_bib19","doi-asserted-by":"crossref","DOI":"10.1038\/hdy.2009.108","article-title":"Transcriptional differences between triploid and diploid Chinook salmon (Oncorhynchus tshawytscha) during live Vibrio anguillarum challenge","author":"Ching","year":"2010","journal-title":"Heredity"},{"key":"10.1016\/j.fsi.2021.05.004_bib20","doi-asserted-by":"crossref","DOI":"10.1111\/are.12584","article-title":"Effect of triploidy in the expression of immune-related genes in coho salmon Oncorhynchus kisutch (Walbaum) infected with Piscirickettsia salmonis","author":"Correa","year":"2015","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.fsi.2021.05.004_bib21","doi-asserted-by":"crossref","DOI":"10.12717\/DR.2017.21.2.193","article-title":"Comparative analysis of tissue and cell cycle on the far Eastern catfish, Silurus asotus between diploid and triploid","author":"Gil","year":"2017","journal-title":"Dev. Reprod."},{"key":"10.1016\/j.fsi.2021.05.004_bib22","doi-asserted-by":"crossref","DOI":"10.1139\/f84-112","article-title":"Use of erythrocyte measurements to identify triploid salmonids","author":"Benfey","year":"1984","journal-title":"Can. J. Fish. Aquat. Sci."},{"key":"10.1016\/j.fsi.2021.05.004_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpb.2004.02.019","article-title":"Haematological parameters in Umbrina cirrosa (Teleostei, Sciaenidae): a comparison between diploid and triploid specimens","author":"Ballarin","year":"2004","journal-title":"Comp. Biochem. Physiol. - A Mol. Integr. Physiol."},{"key":"10.1016\/j.fsi.2021.05.004_bib24","doi-asserted-by":"crossref","DOI":"10.1007\/s10695-007-9176-z","article-title":"Effects of triploidy on the Caspian salmon Salmo trutta caspius haematology","author":"Dorafshan","year":"2008","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.fsi.2021.05.004_bib25","doi-asserted-by":"crossref","DOI":"10.1590\/S1519-69842012000100017","article-title":"Triploidy in the hematology of jundia juveniles (Siluriformes: Heptapteridae)","author":"Fukushima","year":"2012","journal-title":"Braz. J. Biol."},{"key":"10.1016\/j.fsi.2021.05.004_bib26","doi-asserted-by":"crossref","DOI":"10.1127\/archiv-hydrobiol\/149\/2000\/285","article-title":"Temporal trophic shifts and feeding diversity in two sympatric, neotropical, omnivorous fishes: Astyanax bimaculatus and Pimelodus maculatus in Rio Tibagi (Parana, Southern Brazil)","author":"Lobon-Cervia","year":"2000","journal-title":"Arch. Fur Hydrobiol."},{"year":"2001","series-title":"Dieta de Astyanax bimaculatus (Linnaeus, 1758) (Characiformes, Characidae) da \u00e1rea de influ\u00eancia do reservat\u00f3rio de Corumb\u00e1","author":"Andrian","key":"10.1016\/j.fsi.2021.05.004_bib27"},{"author":"Yasui","key":"10.1016\/j.fsi.2021.05.004_bib28"},{"author":"Dos Santos","key":"10.1016\/j.fsi.2021.05.004_bib29"},{"key":"10.1016\/j.fsi.2021.05.004_bib30","doi-asserted-by":"crossref","DOI":"10.1590\/1519-6984.205893","article-title":"In vivo phagocytosis and hematology in Astyanax altiparanae, a potential model for surrogate technology","author":"Levy-Pereira","year":"2020","journal-title":"Braz. J. Biol."},{"key":"10.1016\/j.fsi.2021.05.004_bib31","article-title":"Triploid induction in the yellowtail tetra, Astyanax altiparanae, using temperature shock: tools for conservation and aquaculture","author":"de","year":"2017","journal-title":"J. World Aquacult. Soc."},{"key":"10.1016\/j.fsi.2021.05.004_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2017.01.007","article-title":"Growth, fatty acid composition, and reproductive parameters of diploid and triploid yellowtail tetra Astyanax altiparanae","author":"do Nascimento","year":"2017","journal-title":"Aquaculture"},{"author":"Ferreira Do Nascimento","key":"10.1016\/j.fsi.2021.05.004_bib33"},{"key":"10.1016\/j.fsi.2021.05.004_bib34","doi-asserted-by":"crossref","DOI":"10.1111\/are.13433","article-title":"First feeding of diploid and triploid yellowtail tetra Astyanax altiparanae: an initial stage for application in laboratory studies","author":"Bertolini","year":"2018","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.fsi.2021.05.004_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2017.00131","article-title":"A flow cytometry protocol to estimate DNA content in the yellowtail tetra Astyanax altiparanae","author":"Xavier","year":"2017","journal-title":"Front. Genet."},{"key":"10.1016\/j.fsi.2021.05.004_bib36","doi-asserted-by":"crossref","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative CT method","author":"Schmittgen","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.fsi.2021.05.004_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.ygcen.2006.07.010","article-title":"Are lungfish living fossils? Observation on the evolution of the opioid\/orphanin gene family","author":"Lee","year":"2006","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.fsi.2021.05.004_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpa.2007.03.006","article-title":"Haematological characterization of loach Misgurnus anguillicaudatus: comparison among diploid, triploid and tetraploid specimens","author":"Gao","year":"2007","journal-title":"Comp. Biochem. Physiol. - A Mol. Integr. Physiol."},{"key":"10.1016\/j.fsi.2021.05.004_bib39","article-title":"Identification of diploid and triploid red tilapia by using erythrocyte indices","author":"Jayaprasad","year":"2011","journal-title":"Caryologia"},{"key":"10.1016\/j.fsi.2021.05.004_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.cub.2008.07.096","article-title":"Dosage compensation by gene-copy silencing in a triploid hybrid fish","author":"Pala","year":"2008","journal-title":"Curr. Biol."},{"key":"10.1016\/j.fsi.2021.05.004_bib41","doi-asserted-by":"crossref","DOI":"10.1111\/j.1095-8649.2010.02556.x","article-title":"Amitosis-like nuclear division in erythrocytes of triploid rainbow trout Oncorhynchus mykiss","author":"Wang","year":"2010","journal-title":"J. Fish. Biol."},{"key":"10.1016\/j.fsi.2021.05.004_bib42","article-title":"Changes in hematological parameters of Cichlasoma dimerus (Teleostei, Perciformes) exposed to sublethal concentrations of 4-tert-octylphenol","author":"V\u00e1zquez","year":"2014","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.fsi.2021.05.004_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2016.08.049","article-title":"A comparison of the response of diploid and triploid Atlantic salmon (Salmo salar) siblings to a commercial furunculosis vaccine and subsequent experimental infection with Aeromonas salmonicida","author":"Chalmers","year":"2016","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2021.05.004_bib44","doi-asserted-by":"crossref","DOI":"10.1097\/SHK.0000000000000044","article-title":"Neutrophils - a key component of ischemia-reperfusion injury","author":"Schofield","year":"2013","journal-title":"Shock"},{"key":"10.1016\/j.fsi.2021.05.004_bib45","doi-asserted-by":"crossref","DOI":"10.1111\/ajt.13940","article-title":"The role of neutrophils in transplanted organs","author":"Scozzi","year":"2017","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.fsi.2021.05.004_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/S1050-4648(05)80063-4","article-title":"The effect of triploidy on phagocytosis, leucocyte migration, antibody and complement levels of ayu, Plecoglossus altivelis","author":"Kusuda","year":"1991","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2021.05.004_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpa.2006.05.007","article-title":"The activity of several components of the innate immune system in diploid and triploid turbot","author":"Budi\u00f1o","year":"2006","journal-title":"Comp. Biochem. Physiol. - A Mol. Integr. Physiol."},{"key":"10.1016\/j.fsi.2021.05.004_bib48","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0065-2776(08)60642-2","article-title":"Interleukin-1 and its biologically related cytokines","volume":"44","author":"Dinarello","year":"1989","journal-title":"Adv. Immunol."},{"key":"10.1016\/j.fsi.2021.05.004_bib49","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.gene.2015.09.082","article-title":"Molecular characterization and comparative expression analysis of two teleostean pro-inflammatory cytokines, IL-1\u03b2 and IL-8, from Sebastes schlegeli","volume":"575","author":"Herath","year":"2016","journal-title":"Gene"},{"key":"10.1016\/j.fsi.2021.05.004_bib50","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.fsi.2019.01.007","article-title":"Molecular characterization, phylogenetic analysis and adjuvant effect of channel catfish interleukin-1\u03b2s against Streptococcus iniae","volume":"87","author":"Wang","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2021.05.004_bib51","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.immunol.24.021605.090737","article-title":"Transforming growth factor-\u03b2 regulation of immune responses","volume":"24","author":"Li","year":"2006","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.fsi.2021.05.004_bib52","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.immuni.2007.03.014","article-title":"T cell-produced transforming growth factor-\u03b21 controls T cell tolerance and regulates Th1- and Th17-cell differentiation","volume":"26","author":"Li","year":"2007","journal-title":"Immunity"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464821001327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464821001327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T05:27:22Z","timestamp":1760938042000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464821001327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":52,"alternative-id":["S1050464821001327"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2021.05.004","relation":{},"ISSN":["1050-4648"],"issn-type":[{"type":"print","value":"1050-4648"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of triploid induction on innate immunity and hematology in Astyanax altiparanae","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2021.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}