{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T22:14:50Z","timestamp":1792707290858,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012428","name":"Central Public-interest Scientific Institution Basal Research Fund Chinese Academy of Fishery Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010029","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010029","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.fsi.2022.02.051","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T21:53:44Z","timestamp":1645653224000},"page":"113-126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Molecular cloning, expression analysis of the IgT gene and detection of IgT+ B cells in the half-smooth tongue sole (Cynoglossus semilaevis)"],"prefix":"10.1016","volume":"123","author":[{"given":"Lei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yadong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7626-5609","authenticated-orcid":false,"given":"Zhangfan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songlin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2022.02.051_bib1","doi-asserted-by":"crossref","first-page":"104079","DOI":"10.1016\/j.dci.2021.104079","article-title":"Mucosal immunoglobulins of teleost fish: a decade of advances","volume":"121","author":"Salinas","year":"2021","journal-title":"Dev. Comp. Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2022.02.051_bib2","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/ni1166","article-title":"The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z","volume":"6","author":"Danilova","year":"2005","journal-title":"Nat. Immunol."},{"issue":"19","key":"10.1016\/j.fsi.2022.02.051_bib3","doi-asserted-by":"crossref","first-page":"6919","DOI":"10.1073\/pnas.0500027102","article-title":"Discovery of a unique Ig heavy-chain isotype (IgT) in rainbow trout: implications for a distinctive B cell developmental pathway in teleost fish","volume":"102","author":"Hansen","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib4","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s12867-017-0085-0","article-title":"Immunoglobulin T from sea bass (Dicentrarchus labrax L.): molecular characterization, tissue localization and expression after nodavirus infection","volume":"18","author":"Buonocore","year":"2017","journal-title":"BMC Mol. Biol."},{"issue":"9","key":"10.1016\/j.fsi.2022.02.051_bib5","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.3390\/ijms17091571","article-title":"Immunoglobulin tau heavy chain (IgT) in flounder, Paralichthys olivaceus: molecular cloning, characterization, and expression analyses","volume":"17","author":"Du","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.fsi.2022.02.051_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetimm.2018.07.011","article-title":"Molecular cloning and expression analyses of immunoglobulin tau heavy chain (IgT) in turbot, Scophthalmus maximus","volume":"203","author":"Tang","year":"2018","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.vetimm.2010.07.024","article-title":"Molecular cloning of IgT from Atlantic salmon, and analysis of the relative expression of tau, mu, and delta in different tissues","volume":"139","author":"Tadiso","year":"2011","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"6","key":"10.1016\/j.fsi.2022.02.051_bib8","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1007\/s00251-005-0015-z","article-title":"Discovery of a novel immunoglobulin heavy chain gene chimera from common carp (Cyprinus carpio L.)","volume":"57","author":"Savan","year":"2005","journal-title":"Immunogenetics"},{"issue":"11","key":"10.1016\/j.fsi.2022.02.051_bib9","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.dci.2010.06.012","article-title":"Common carp have two subclasses of bonyfish specific antibody IgZ showing differential expression in response to infection","volume":"34","author":"Ryo","year":"2010","journal-title":"Dev. Comp. Immunol."},{"issue":"4","key":"10.1016\/j.fsi.2022.02.051_bib10","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.molimm.2009.10.010","article-title":"Identification and characterization of a novel immunoglobulin Z isotype in zebrafish: implications for a distinct B cell receptor in lower vertebrates","volume":"47","author":"Hu","year":"2010","journal-title":"Mol. Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib11","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12917-021-02844-7","article-title":"Molecular characterization of a new IgZ3 subclass in common carp (Cyprinus carpio) and comparative expression analysis of IgH transcripts during larvae development","volume":"17","author":"Zhang","year":"2021","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.fsi.2022.02.051_bib12","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.dci.2017.01.001","article-title":"Molecular characterization and expression analysis of three subclasses of IgT in rainbow trout (Oncorhynchus mykiss)","volume":"70","author":"Zhang","year":"2017","journal-title":"Dev. Comp. Immunol."},{"issue":"9","key":"10.1016\/j.fsi.2022.02.051_bib13","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/ni.1913","article-title":"IgT, a primitive immunoglobulin class specialized in mucosal immunity","volume":"11","author":"Zhang","year":"2010","journal-title":"Nat. Immunol."},{"issue":"11","key":"10.1016\/j.fsi.2022.02.051_bib14","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.1002\/eji.200535248","article-title":"Discovery of a new class of immunoglobulin heavy chain from fugu","volume":"35","author":"Savan","year":"2005","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.fsi.2022.02.051_bib15","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.fsi.2018.12.064","article-title":"Immunoglobulin (Ig) heavy chain gene locus and immune responses upon parasitic, bacterial and fungal infection in loach, Misgurnus anguillicaudatus","volume":"86","author":"Xu","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2022.02.051_bib16","doi-asserted-by":"crossref","first-page":"737291","DOI":"10.1016\/j.aquaculture.2021.737291","article-title":"Molecular cloning of IgT, IgD and analysis the IgH locus in largemouth bass (Micropterus salmoides) and immune response upon bacterial infection","volume":"546","author":"Han","year":"2021","journal-title":"Aquaculture"},{"issue":"44","key":"10.1016\/j.fsi.2022.02.051_bib17","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aay3254","article-title":"Specialization of mucosal immunoglobulins in pathogen control and microbiota homeostasis occurred early in vertebrate evolution","volume":"5","author":"Xu","year":"2020","journal-title":"Sci Immunol"},{"issue":"11","key":"10.1016\/j.fsi.2022.02.051_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007251","article-title":"Mucosal immunoglobulins protect the olfactory organ of teleost fish against parasitic infection","volume":"14","author":"Yu","year":"2018","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.fsi.2022.02.051_bib19","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.fsi.2018.12.064","article-title":"Immunoglobulin (Ig) heavy chain gene locus and immune responses upon parasitic, bacterial and fungal infection in loach","volume":"86","author":"Xu","year":"2019","journal-title":"Misgurnus anguillicaudatus. Fish and Shellfish Immunology"},{"issue":"32","key":"10.1016\/j.fsi.2022.02.051_bib20","doi-asserted-by":"crossref","first-page":"13097","DOI":"10.1073\/pnas.1304319110","article-title":"Teleost skin, an ancient mucosal surface that elicits gut-like immune responses","volume":"110","author":"Xu","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/j.fsi.2022.02.051_bib21","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.4049\/jimmunol.2001097","article-title":"Prevailing role of mucosal Igs and B cells in teleost skin immune responses to bacterial infection","volume":"206","author":"Zhang","year":"2021","journal-title":"J. Immunol."},{"issue":"7","key":"10.1016\/j.fsi.2022.02.051_bib22","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1039\/C5MB00890E","article-title":"Immune relevant molecules identified in the skin mucus of fish using -omics technologies","volume":"12","author":"Brinchmann","year":"2016","journal-title":"Mol. Biosyst."},{"issue":"3","key":"10.1016\/j.fsi.2022.02.051_bib23","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/ng.2890","article-title":"Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle","volume":"46","author":"Chen","year":"2014","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.fsi.2022.02.051_bib24","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0161-5890(94)90069-8","article-title":"Complete nucleotide sequence of a rainbow trout cDNA encoding a membrane-bound form of immunoglobulin heavy chain","volume":"31","author":"Hansen","year":"1994","journal-title":"Mol. Immunol."},{"issue":"4","key":"10.1016\/j.fsi.2022.02.051_bib25","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1007\/s00251-004-0689-7","article-title":"Genes of the constant regions of functional immunoglobulin heavy chain of Japanese flounder, Paralichthys olivaceus","volume":"56","author":"Srisapoome","year":"2004","journal-title":"Immunogenetics"},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib26","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S1050-4648(02)00139-0","article-title":"Cloning and characterisation of a cDNA encoding Japanese flounder Paralichthys olivaceus IgD","volume":"15","author":"Hirono","year":"2003","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib27","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.vetimm.2010.07.024","article-title":"Molecular cloning of IgT from Atlantic salmon, and analysis of the relative expression of tau, mu, and delta in different tissues","volume":"139","author":"Tadiso","year":"2011","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"11","key":"10.1016\/j.fsi.2022.02.051_bib28","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1002\/eji.1830221130","article-title":"Cloning and sequence analysis of two isotypic IgM heavy chain genes from Atlantic salmon, Salmo salar L","volume":"22","author":"Hordvik","year":"1992","journal-title":"Eur. J. Immunol."},{"issue":"2","key":"10.1016\/j.fsi.2022.02.051_bib29","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1046\/j.1365-3083.1999.00583.x","article-title":"Molecular cloning and phylogenetic analysis of the Atlantic salmon immunoglobulin D gene","volume":"50","author":"Hordvik","year":"1999","journal-title":"Scand. J. Immunol."},{"issue":"2\u20133","key":"10.1016\/j.fsi.2022.02.051_bib30","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0165-2478(97)00145-4","article-title":"Molecular cloning of the cDNA encoding the constant region of the immunoglobulin A heavy chain (C alpha) from a marsupial: Trichosurus vulpecula (common brushtail possum)","volume":"60","author":"Belov","year":"1998","journal-title":"Immunol. Lett."},{"issue":"4","key":"10.1016\/j.fsi.2022.02.051_bib31","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.fsi.2010.06.004","article-title":"Ig heavy chain genes and their locus in grass carp Ctenopharyngodon idella","volume":"29","author":"Xiao","year":"2010","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib32","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.molimm.2004.06.034","article-title":"Analysis and characterization of the expression of the secretory and membrane forms of IgM heavy chains in the pufferfish, Takifugu rubripes","volume":"42","author":"Saha","year":"2005","journal-title":"Mol. Immunol."},{"issue":"6","key":"10.1016\/j.fsi.2022.02.051_bib33","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/s00251-004-0693-y","article-title":"Fugu immunoglobulin D: a highly unusual gene with unprecedented duplications in its constant region","volume":"56","author":"Saha","year":"2004","journal-title":"Immunogenetics"},{"issue":"3\u20134","key":"10.1016\/j.fsi.2022.02.051_bib34","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.vetimm.2005.08.029","article-title":"Characterization of serum immunoglobulin M of grouper and cDNA cloning of its heavy chain","volume":"109","author":"Cheng","year":"2006","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"8","key":"10.1016\/j.fsi.2022.02.051_bib35","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/nmeth.1638","article-title":"A public genome-scale lentiviral expression library of human ORFs","volume":"8","author":"Yang","year":"2011","journal-title":"Nat. Methods"},{"issue":"10","key":"10.1016\/j.fsi.2022.02.051_bib36","doi-asserted-by":"crossref","first-page":"6027","DOI":"10.1073\/pnas.77.10.6027","article-title":"Cloning and partial nucleotide sequence of human immunoglobulin mu chain cDNA from B cells and mouse-human hybridomas","volume":"77","author":"Dolby","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5859","key":"10.1016\/j.fsi.2022.02.051_bib37","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/296761a0","article-title":"Mouse immunoglobulin allotypes: post-duplication divergence of gamma 2a and gamma 2b chain genes","volume":"296","author":"Ollo","year":"1982","journal-title":"Nature"},{"issue":"17","key":"10.1016\/j.fsi.2022.02.051_bib38","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1093\/nar\/8.17.3933","article-title":"Complete nucleotide sequence of mouse immunoglobulin mu gene and comparison with other immunoglobulin heavy chain genes","volume":"8","author":"Kawakami","year":"1980","journal-title":"Nucleic Acids Res."},{"issue":"3","key":"10.1016\/j.fsi.2022.02.051_bib39","doi-asserted-by":"crossref","first-page":"855","DOI":"10.4049\/jimmunol.149.3.855","article-title":"Chicken IgA H chains. Implications concerning the evolution of H chain genes","volume":"149","author":"Mansikka","year":"1992","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib40","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.fsi.2010.02.021","article-title":"beta-Actin is a useful internal control for tissue-specific gene expression studies using quantitative real-time PCR in the half-smooth tongue sole Cynoglossus semilaevis challenged with LPS or Vibrio anguillarum","volume":"29","author":"Li","year":"2010","journal-title":"Fish Shellfish Immunol."},{"issue":"4","key":"10.1016\/j.fsi.2022.02.051_bib41","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2022.02.051_bib42","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.fsi.2017.05.016","article-title":"Molecular cloning, biological effect, and tissue distribution of interleukin-8 protein in Mandarin fish (Siniperca chuasti) upon Flavobacterium columnare infection","volume":"66","author":"Wang","year":"2017","journal-title":"Fish Shellfish Immunol."},{"issue":"19","key":"10.1016\/j.fsi.2022.02.051_bib43","doi-asserted-by":"crossref","first-page":"4960","DOI":"10.1111\/j.1742-4658.2005.04906.x","article-title":"Isolation and identification of antimicrobial components from the epidermal mucus of Atlantic cod (Gadus morhua)","volume":"272","author":"Bergsson","year":"2005","journal-title":"FEBS J."},{"issue":"5","key":"10.1016\/j.fsi.2022.02.051_bib44","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1093\/jb\/mvr085","article-title":"A unique epidermal mucus lectin identified from catfish (Silurus asotus): first evidence of intelectin in fish skin slime","volume":"150","author":"Tsutsui","year":"2011","journal-title":"J. Biochem."},{"key":"10.1016\/j.fsi.2022.02.051_bib45","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.fsi.2018.02.006","article-title":"Mucus glycosylation, immunity and bacterial microbiota associated to the skin of experimentally ulcered gilthead seabream (Sparus aurata)","volume":"75","author":"Tapia-Paniagua","year":"2018","journal-title":"Fish Shellfish Immunol."},{"issue":"12","key":"10.1016\/j.fsi.2022.02.051_bib46","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.dci.2011.11.009","article-title":"Mucosal immunoglobulins and B cells of teleost fish","volume":"35","author":"Salinas","year":"2011","journal-title":"Dev. Comp. Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib47","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/ng.3732","article-title":"The genome and transcriptome of Japanese flounder provide insights into flatfish asymmetry","volume":"49","author":"Shao","year":"2017","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.fsi.2022.02.051_bib48","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/s41597-020-0426-6","article-title":"Draft genomes of female and male turbot Scophthalmus maximus","volume":"7","author":"Xu","year":"2020","journal-title":"Sci. Data"},{"issue":"6","key":"10.1016\/j.fsi.2022.02.051_bib49","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1006\/smim.1994.1049","article-title":"CART: a conserved antigen receptor transmembrane motif","volume":"6","author":"Campbell","year":"1994","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.fsi.2022.02.051_bib50","doi-asserted-by":"crossref","first-page":"104027","DOI":"10.1016\/j.dci.2021.104027","article-title":"Development of monoclonal antibody against IgT of a perciform fish, large yellow croaker (Larimichthys crocea) and characterization of IgT+ B cells","volume":"119","author":"Fu","year":"2021","journal-title":"Dev. Comp. Immunol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464822001139?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464822001139?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T05:31:19Z","timestamp":1760938279000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464822001139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":50,"alternative-id":["S1050464822001139"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2022.02.051","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular cloning, expression analysis of the IgT gene and detection of IgT+ B cells in the half-smooth tongue sole (Cynoglossus semilaevis)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2022.02.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}