{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T19:31:38Z","timestamp":1790451098356,"version":"4.1.0"},"reference-count":83,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.fsi.2022.09.029","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T12:20:38Z","timestamp":1663330838000},"page":"317-322","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Antioxidative and immunostimulant potential of fruit derived biomolecules in aquaculture"],"prefix":"10.1016","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0067-2838","authenticated-orcid":false,"given":"Ola A.","family":"Habotta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud A.O.","family":"Dawood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulhisyam Abdul","family":"Kari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanaporn","family":"Tapingkae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hien","family":"Van Doan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2022.09.029_bib1","series-title":"Pulsed Electric Field: A Potential Alternative towards a Sustainable Food Processing","author":"Arshad","year":"2021"},{"issue":"9","key":"10.1016\/j.fsi.2022.09.029_bib2","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.3390\/molecules26092632","article-title":"Anthocyanins recovered from agri-food by-products using innovative processes: trends, challenges, and perspectives for their application in food systems","volume":"26","author":"Arruda","year":"2021","journal-title":"Molecules"},{"issue":"3","key":"10.1016\/j.fsi.2022.09.029_bib3","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/1541-4337.12330","article-title":"Fruit and vegetable waste: bioactive compounds, their extraction, and possible utilization","volume":"17","author":"Sagar","year":"2018","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.fsi.2022.09.029_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.116796","article-title":"Current trends and possibilities for exploitation of Grape pomace as a potential source for value addition","volume":"278","author":"Chowdhary","year":"2021","journal-title":"Environ. Pollut."},{"issue":"3","key":"10.1016\/j.fsi.2022.09.029_bib5","doi-asserted-by":"crossref","first-page":"657","DOI":"10.3390\/foods10030657","article-title":"Nutritional and bioactive components of pomegranate waste used in food and cosmetic applications: a review","volume":"10","author":"Ko","year":"2021","journal-title":"Foods"},{"issue":"3","key":"10.1016\/j.fsi.2022.09.029_bib6","doi-asserted-by":"crossref","first-page":"510","DOI":"10.3390\/molecules25030510","article-title":"Bioactives from agri-food wastes: present insights and future challenges","volume":"25","author":"Ben-Othman","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.fsi.2022.09.029_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.fsi.2020.04.019","article-title":"The potential benefits of orange peels derived pectin on serum and skin mucus immune parameters, antioxidant defence and growth performance in common carp (Cyprinus carpio)","volume":"103","author":"Hosseini","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2022.09.029_bib8","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.fsi.2021.04.002","article-title":"Impacts of pineapple peel powder on growth performance, innate immunity, disease resistance, and relative immune gene expression of Nile tilapia, Oreochromis niloticus","volume":"114","author":"Van Doan","year":"2021","journal-title":"Fish Shellfish Immunol."},{"issue":"7","key":"10.1016\/j.fsi.2022.09.029_bib9","doi-asserted-by":"crossref","first-page":"843","DOI":"10.3390\/foods9070843","article-title":"Exploitation of agro-industrial waste as potential source of bioactive compounds for aquaculture","volume":"9","author":"Leyva-L\u00f3pez","year":"2020","journal-title":"Foods"},{"key":"10.1016\/j.fsi.2022.09.029_bib10","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.fsi.2021.01.011","article-title":"Impact of grape pomace flour (GPF) on immunity and immune-antioxidant-anti-inflammatory genes expression in Labeo rohita against Flavobacterium columnaris","volume":"111","author":"Harikrishnan","year":"2021","journal-title":"Fish Shellfish Immunol."},{"issue":"4","key":"10.1016\/j.fsi.2022.09.029_bib11","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1111\/raq.12680","article-title":"Fruit processing by-products in the aquafeed industry: a feasible strategy for aquaculture sustainability","volume":"14","author":"Dawood","year":"2022","journal-title":"Rev. Aquacult."},{"issue":"7","key":"10.1016\/j.fsi.2022.09.029_bib12","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.1002\/fsn3.1665","article-title":"Biologically active components in by\u2010products of food processing","volume":"8","author":"Galali","year":"2020","journal-title":"Food Sci. Nutr."},{"key":"10.1016\/j.fsi.2022.09.029_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2020.109086","article-title":"Recovery of high value-added compounds from pineapple, melon, watermelon and pumpkin processing by-products: an overview","volume":"132","author":"Rico","year":"2020","journal-title":"Food Res. Int."},{"issue":"3","key":"10.1016\/j.fsi.2022.09.029_bib14","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0308-8146(01)00157-1","article-title":"Comparison of some biochemical characteristics of different citrus fruits","volume":"74","author":"Gorinstein","year":"2001","journal-title":"Food Chem."},{"issue":"11","key":"10.1016\/j.fsi.2022.09.029_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0224995","article-title":"Effects of dietary supplementation with apple peel powder on the growth, blood and liver parameters, and transcriptome of genetically improved farmed tilapia (GIFT, Oreochromis niloticus)","volume":"14","author":"Qiang","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.fsi.2022.09.029_bib16","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.fsi.2020.04.019","article-title":"The potential benefits of orange peels derived pectin on serum and skin mucus immune parameters, antioxidant defence and growth performance in common carp (Cyprinus carpio)","volume":"103","author":"Hosseini","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2022.09.029_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104202","article-title":"Pomegranate peel and moringa-based diets enhanced biochemical and immune parameters of Nile tilapia against bacterial infection by Aeromonas hydrophila","volume":"145","author":"Monir","year":"2020","journal-title":"Microb. Pathog."},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib18","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s10695-019-00700-y","article-title":"Effects of bergamot (Citrus bergamia) peel oil-supplemented diets on growth performance, haematology and serum biochemical parameters of Nile tilapia (Oreochromis niloticus)","volume":"46","author":"Kesbi\u00e7","year":"2020","journal-title":"Fish Physiol. Biochem."},{"issue":"4","key":"10.1016\/j.fsi.2022.09.029_bib19","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1080\/87559129.2019.1573431","article-title":"Plant food by-products as feed: characteristics, possibilities, environmental benefits, and negative sides","volume":"35","author":"\u010colovi\u0107","year":"2019","journal-title":"Food Rev. Int."},{"issue":"9","key":"10.1016\/j.fsi.2022.09.029_bib20","first-page":"1074","article-title":"Effects of ensiled apple pomace on milk yield, milk composition and DM intake of Holstein dairy cows","volume":"6","author":"Ghoreishi","year":"2007","journal-title":"J. Anim. Vet. Adv."},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib21","first-page":"120","article-title":"Inclusion of dried mango (Mangifera indica) peels in finisher rations of pigs on their performance","volume":"20","author":"Rao","year":"2003","journal-title":"Indian J. Anim. Nutr."},{"key":"10.1016\/j.fsi.2022.09.029_bib22","first-page":"89","article-title":"Effects of ripe plantain peel (musa cv.) on growth and carcass performance of growing rabbits","volume":"19","author":"Fanimo","year":"1996","journal-title":"Pertanika J. Trop. Agric. Sci."},{"issue":"4","key":"10.1016\/j.fsi.2022.09.029_bib23","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1080\/00071668.2010.506908","article-title":"Dietary plant bioactives for poultry health and productivity","volume":"51","author":"Wallace","year":"2010","journal-title":"Br. Poultry Sci."},{"issue":"4","key":"10.1016\/j.fsi.2022.09.029_bib24","first-page":"1022","article-title":"Dietary pomegranate by-product alleviated the oxidative stress induced by dexamethasone in laying hens in the pre-peak period","volume":"11","author":"Eid","year":"2021","journal-title":"Anim."},{"key":"10.1016\/j.fsi.2022.09.029_bib25","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.micpath.2019.02.024","article-title":"Grape pomace flour alleviates Pseudomonas aeruginosa-induced hepatic oxidative stress in grass carp by improving antioxidant defense","volume":"129","author":"Souza","year":"2019","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.fsi.2022.09.029_bib26","first-page":"2016","article-title":"Dietary administration of banana (Musa acuminata) peel flour affects the growth, antioxidant status, cytokine responses, and disease susceptibility of rohu, Labeo rohita","author":"Giri","year":"2016","journal-title":"J. Immunol. Res"},{"issue":"2","key":"10.1016\/j.fsi.2022.09.029_bib27","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.fsi.2014.05.031","article-title":"Effects of hot-water extract of banana (Musa acuminata) fruit\u2019s peel on the antibacterial activity, and anti-hypothermal stress, immune responses and disease resistance of the giant freshwater prawn, Macrobrachium rosenbegii","volume":"39","author":"Rattanavichai","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2022.09.029_bib28","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.fsi.2019.10.066","article-title":"Chinese yam peel enhances the immunity of the common carp (Cyprinus carpio L.) by improving the gut defence barrier and modulating the intestinal microflora","volume":"95","author":"Meng","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2022.09.029_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125423","article-title":"Toxic effects on bioaccumulation, hematological parameters, oxidative stress, immune responses and neurotoxicity in fish exposed to microplastics: a review","volume":"413","author":"Kim","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.fsi.2022.09.029_bib30","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.fsi.2019.12.059","article-title":"Toxic effects of waterborne nitrite exposure on antioxidant responses, acetylcholinesterase inhibition, and immune responses in olive flounders, Paralichthys olivaceus, reared in bio-floc and seawater","volume":"97","author":"Kim","year":"2020","journal-title":"Fish Shellfish Immunol."},{"issue":"11","key":"10.1016\/j.fsi.2022.09.029_bib31","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0924-2244(01)00027-9","article-title":"Some methodological problems in the determination of antioxidant activity using chromogen radicals: a practical case","volume":"11","author":"Arnao","year":"2000","journal-title":"Trends Food Sci. Technol."},{"issue":"10","key":"10.1016\/j.fsi.2022.09.029_bib32","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1007\/s13197-012-0793-x","article-title":"Enhanced yield of phenolic extracts from banana peels (Musa acuminata Colla AAA) and cinnamon barks (Cinnamomum varum) and their antioxidative potentials in fish oil","volume":"51","author":"Anal","year":"2014","journal-title":"J. Food Sci. Technol."},{"issue":"1\u20132","key":"10.1016\/j.fsi.2022.09.029_bib33","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.foodchem.2013.02.040","article-title":"Antioxidant ability of fractionated apple peel phenolics to inhibit fish oil oxidation","volume":"140","author":"Sekhon-Loodu","year":"2013","journal-title":"Food Chem."},{"issue":"4","key":"10.1016\/j.fsi.2022.09.029_bib34","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.biortech.2005.03.037","article-title":"Studies on the development of functional powder from citrus peel","volume":"97","author":"Kang","year":"2006","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.fsi.2022.09.029_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2019.734412","article-title":"Modulation of immune parameters and antioxidant defense in zebrafish (Danio rerio) using dietary apple cider vinegar","volume":"513","author":"Ahmadifar","year":"2019","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2022.09.029_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2020.736311","article-title":"Dietary apple peel-derived pectin improved growth performance, antioxidant enzymes and immune response in common carp, Cyprinus carpio (Linnaeus, 1758)","volume":"535","author":"Hoseinifar","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2022.09.029_bib37","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.fsi.2017.06.017","article-title":"Apple cider vinegar boosted immunomodulatory and health-promoting effects of Lactobacillus casei in common carp (Cyprinus carpio)","volume":"67","author":"Safari","year":"2017","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib38","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/jwas.12750","article-title":"Lemon, Citrus aurantifolia, peel and Bacillus licheniformis protected common carp, Cyprinus carpio, from Aeromonas hydrophila infection by improving the humoral and skin mucosal immunity, and antioxidative responses","volume":"52","author":"Sadeghi","year":"2021","journal-title":"J. World Aquacult. Soc."},{"key":"10.1016\/j.fsi.2022.09.029_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2020.736284","article-title":"Apple polyphenols modulates the antioxidant defense response and attenuates inflammatory response concurrent with hepatoprotective effect on grass carp (Ctenopharyngodon idellus) fed low fish meal diet","volume":"534","author":"Yang","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2022.09.029_bib40","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/4086591","article-title":"Dietary administration of banana (Musa acuminata) peel flour affects the growth, antioxidant status, cytokine responses, and disease susceptibility of rohu, Labeo rohita","volume":"2016","author":"Giri","year":"2016","journal-title":"J. Immunol. Res."},{"issue":"2","key":"10.1016\/j.fsi.2022.09.029_bib41","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.fsi.2015.06.031","article-title":"The effect of banana (Musa acuminata) peels hot-water extract on the immunity and resistance of giant freshwater prawn, Macrobrachium rosenbergii via dietary administration for a long term: activity and gene transcription","volume":"46","author":"Rattanavichai","year":"2015","journal-title":"Fish Shellfish Immunol."},{"issue":"2","key":"10.1016\/j.fsi.2022.09.029_bib42","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.fsi.2015.01.011","article-title":"Dietary supplement of banana (Musa acuminata) peels hot-water extract to enhance the growth, anti-hypothermal stress, immunity and disease resistance of the giant freshwater prawn, Macrobrachium rosenbergii","volume":"43","author":"Rattanavichai","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2022.09.029_bib43","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.fsi.2017.03.042","article-title":"Dietary dehydrated lemon peel improves the immune but not the antioxidant status of gilthead seabream (Sparus aurataL.)","volume":"64","author":"Garc\u00eda Beltr\u00e1n","year":"2017","journal-title":"Fish Shellfish Immunol."},{"issue":"5","key":"10.1016\/j.fsi.2022.09.029_bib44","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1111\/anu.12925","article-title":"Effects of dietary orange peel on growth performance, antioxidant activity, intestinal microbiota and liver histology of Gilthead sea bream (Sparus aurata) larvae","volume":"25","author":"Salem","year":"2019","journal-title":"Aquacult. Nutr."},{"issue":"11","key":"10.1016\/j.fsi.2022.09.029_bib45","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1111\/are.14272","article-title":"Effects of dietary dehydrated lemon peel on some biochemical markers related to general metabolism, welfare and stress in gilthead seabream (Sparus aurata L.)","volume":"50","author":"Garc\u00eda Beltr\u00e1n","year":"2019","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.fsi.2022.09.029_bib46","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.fsi.2020.07.040","article-title":"Dried lemon peel enriched diet improves antioxidant activity, immune response and modulates immuno-antioxidant genes in Labeo rohita against Aeromonas sorbia","volume":"106","author":"Harikrishnan","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2022.09.029_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.736597","article-title":"Effect of dietary dehydrated lemon peel (Citrus limon) supplementation on growth, hemato-immunological and antioxidant status of rainbow trout (Oncorhynchus mykiss) under exposure to crowding stress","volume":"539","author":"Chekani","year":"2021","journal-title":"Aquaculture"},{"issue":"3","key":"10.1016\/j.fsi.2022.09.029_bib48","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s10695-019-00716-4","article-title":"Administration of grape (Vitis vinifera) seed extract to rainbow trout (Oncorhynchus mykiss) modulates growth performance, some biochemical parameters, and antioxidant-relevant gene expression","volume":"46","author":"Mousavi","year":"2020","journal-title":"Fish Physiol. Biochem."},{"issue":"6","key":"10.1016\/j.fsi.2022.09.029_bib49","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1111\/are.13686","article-title":"Effects of grape Vitis vinifera seed oil supplementation on growth, survival, fatty acid profiles, antioxidant contents and blood parameters in rainbow trout Oncorhynchus mykiss","volume":"49","author":"Arslan","year":"2018","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.fsi.2022.09.029_bib50","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.aquaculture.2019.02.051","article-title":"Efficacy of the dehydrated lemon peels on the immunity, enzymatic antioxidant capacity and growth of Nile tilapia (Oreochromis niloticus) and African catfish (Clarias gariepinus)","volume":"505","author":"Abdel Rahman","year":"2019","journal-title":"Aquaculture"},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib51","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/are.13870","article-title":"Orange peel fragment improves antioxidant capacity and haematological profile of Nile tilapia subjected to heat\/dissolved oxygen-induced stress","volume":"50","author":"Vicente","year":"2019","journal-title":"Aquacult. Res."},{"issue":"2","key":"10.1016\/j.fsi.2022.09.029_bib52","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1007\/s11356-020-10599-1","article-title":"Bioremediation effect of pomegranate peel on subchronic mercury immunotoxicity on African catfish (Clarias gariepinus)","volume":"28","author":"El-Bouhy","year":"2021","journal-title":"Environ. Sci. Pollut. Control Ser."},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib53","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3390\/antiox9010010","article-title":"Antagonistic efficacy of luteolin against lead acetate exposure-associated with hepatotoxicity is mediated via antioxidant, anti-inflammatory, and anti-apoptotic activities","volume":"9","author":"Al-Megrin","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.fsi.2022.09.029_bib54","doi-asserted-by":"crossref","DOI":"10.1007\/s11356-021-13145-9","article-title":"Does the adsorbent capacity of orange and banana peels toward silver nanoparticles improve the biochemical status of Oreochromis niloticus?","author":"Abdel-Khalek","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"6","key":"10.1016\/j.fsi.2022.09.029_bib55","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1093\/carcin\/bgr045","article-title":"Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms","volume":"32","author":"Bishayee","year":"2011","journal-title":"Carcinogenesis"},{"issue":"4","key":"10.1016\/j.fsi.2022.09.029_bib56","doi-asserted-by":"crossref","first-page":"602","DOI":"10.3856\/vol47-issue4-fulltext-3","article-title":"Effect of dietary intake of phenolic compounds from mango peel extract on growth, lipid peroxidation and antioxidant enzyme activities in zebrafish (Danio rerio)","volume":"47","author":"Liz\u00e1rraga-Vel\u00e1zquez","year":"2019","journal-title":"Latin Am J Aquatic Res"},{"issue":"3","key":"10.1016\/j.fsi.2022.09.029_bib57","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s10695-019-00716-4","article-title":"Administration of grape (Vitis vinifera) seed extract to rainbow trout (Oncorhynchus mykiss) modulates growth performance, some biochemical parameters, and antioxidant-relevant gene expression","volume":"46","author":"Mousavi","year":"2020","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.fsi.2022.09.029_bib58","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.fsi.2020.07.040","article-title":"Dried lemon peel enriched diet improves antioxidant activity, immune response and modulates immuno-antioxidant genes in Labeo rohita against Aeromonas sorbia","volume":"106","author":"Harikrishnan","year":"2020","journal-title":"Fish Shellfish Immunol."},{"issue":"11","key":"10.1016\/j.fsi.2022.09.029_bib59","doi-asserted-by":"crossref","DOI":"10.1002\/cbdv.201900400","article-title":"Recent advances of natural polyphenols activators for keap1-nrf2 signaling pathway","volume":"16","author":"Zhou","year":"2019","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.fsi.2022.09.029_bib60","first-page":"1","article-title":"Luteolin protects against lead acetate-induced nephrotoxicity through antioxidant, anti-inflammatory, anti-apoptotic, and Nrf2\/HO-1 signaling pathways","author":"Albarakati","year":"2020","journal-title":"Mol. Biol. Rep."},{"issue":"12","key":"10.1016\/j.fsi.2022.09.029_bib61","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.13505","article-title":"Ferulic acid influences Nrf2 activation to restore testicular tissue from cadmium\u2010induced oxidative challenge, inflammation, and apoptosis in rats","volume":"44","author":"Kassab","year":"2020","journal-title":"J. Food Biochem."},{"key":"10.1016\/j.fsi.2022.09.029_bib62","first-page":"56","article-title":"Antioxidative, anti-inflammatory and hepatoprotective effects of resveratrol on oxidative stress-induced liver damage in tilapia (Oreochromis niloticus), Comparative biochemistry and physiology","volume":"215","author":"Jia","year":"2019","journal-title":"Toxicol. Pharmacol.\u202f: CBP"},{"key":"10.1016\/j.fsi.2022.09.029_bib63","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.fsi.2017.03.042","article-title":"Dietary dehydrated lemon peel improves the immune but not the antioxidant status of gilthead seabream (Sparus aurata L.)","volume":"64","author":"Beltr\u00e1n","year":"2017","journal-title":"Fish Shellfish Immunol."},{"issue":"2","key":"10.1016\/j.fsi.2022.09.029_bib64","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s10695-021-00930-z","article-title":"Changes in rainbow trout (Oncorhynchus mykiss) growth and mucosal immune parameters after dietary administration of grape (Vitis vinifera) seed extract","volume":"47","author":"Mousavi","year":"2021","journal-title":"Fish Physiol. Biochem."},{"issue":"2","key":"10.1016\/j.fsi.2022.09.029_bib65","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00403-009-1001-3","article-title":"Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms","volume":"302","author":"Nichols","year":"2010","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.fsi.2022.09.029_bib66","article-title":"An overview of the immunological defenses in fish skin","volume":"2012","author":"\u00c1ngeles Esteban","year":"2012","journal-title":"Int. Sch. Res. Notices"},{"issue":"4","key":"10.1016\/j.fsi.2022.09.029_bib67","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s10695-019-00649-y","article-title":"Immuno-physiological and antioxidant responses of Siberian sturgeon (Acipenser baerii) fed with different levels of olive pomace","volume":"45","author":"Banavreh","year":"2019","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.fsi.2022.09.029_bib68","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.fsi.2018.05.049","article-title":"Effects of orange peels derived pectin on innate immune response, disease resistance and growth performance of Nile tilapia (Oreochromis niloticus) cultured under indoor biofloc system","volume":"80","author":"Van Doan","year":"2018","journal-title":"Fish Shellfish Immunol."},{"issue":"7","key":"10.1016\/j.fsi.2022.09.029_bib69","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/jfd.12035","article-title":"Effects of dietary supplementation of citrus by\u2010products fermented with a probiotic microbe on growth performance, innate immunity and disease resistance against Edwardsiella tarda in juvenile olive flounder, Paralichthys olivaceus (T emminck & S chlegel)","volume":"36","author":"Lee","year":"2013","journal-title":"J. Fish. Dis."},{"issue":"8","key":"10.1016\/j.fsi.2022.09.029_bib70","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1016\/j.biortech.2007.05.067","article-title":"Removal of methylene blue dye from aqueous solutions by adsorption using yellow passion fruit peel as adsorbent","volume":"99","author":"Pavan","year":"2008","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.fsi.2022.09.029_bib71","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.eti.2018.05.006","article-title":"Water purification by using adsorbents: a review","volume":"11","author":"Singh","year":"2018","journal-title":"Environ. Technol. Innovat."},{"issue":"2","key":"10.1016\/j.fsi.2022.09.029_bib72","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.colsurfb.2009.12.016","article-title":"Biosorption optimization of nickel removal from water using Punica granatum peel waste","volume":"76","author":"Bhatnagar","year":"2010","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.fsi.2022.09.029_bib73","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.colsurfb.2012.05.013","article-title":"Characterization of Punica granatum L. peels and quantitatively determination of its biosorption behavior towards lead (II) ions and Acid Blue 40","volume":"100","author":"Ay","year":"2012","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"1\u20133","key":"10.1016\/j.fsi.2022.09.029_bib74","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.desal.2007.01.206","article-title":"Removal of lead (II) and copper (II) from aqueous solution using pomegranate peel as a new adsorbent","volume":"223","author":"El-Ashtoukhy","year":"2008","journal-title":"Desalination"},{"key":"10.1016\/j.fsi.2022.09.029_bib75","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1016\/j.jclepro.2016.10.081","article-title":"Characterization and adsorption capacity of raw pomegranate peel biosorbent for copper removal","volume":"142","author":"Ben-Ali","year":"2017","journal-title":"J. Clean. Prod."},{"issue":"5","key":"10.1016\/j.fsi.2022.09.029_bib76","first-page":"477","article-title":"The adsorption of zinc metal in wastewater using ZnCl2 activated pomegranate peel","volume":"9","author":"Turkmen","year":"2015","journal-title":"Int. J. Mater. Metallurg. Eng."},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib77","first-page":"1","article-title":"Removal of Fe (II) from aqueous solution using pomegranate peel carbon: equilibrium and kinetic studies","volume":"4","author":"Moghadam","year":"2013","journal-title":"Int. J. Integrated Care"},{"key":"10.1016\/j.fsi.2022.09.029_bib78","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.jhazmat.2012.01.084","article-title":"Optimization and kinetic modeling of cadmium desorption from citrus peels: a process for biosorbent regeneration","volume":"213","author":"Njikam","year":"2012","journal-title":"J. Hazard Mater."},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib79","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jhazmat.2010.08.114","article-title":"Biosorption of heavy metals from aqueous solutions by chemically modified orange peel","volume":"185","author":"Feng","year":"2011","journal-title":"J. Hazard Mater."},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib80","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jhazmat.2008.06.084","article-title":"Grape waste as a biosorbent for removing Cr (VI) from aqueous solution","volume":"163","author":"Chand","year":"2009","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.fsi.2022.09.029_bib81","article-title":"Dried biosorbent derived from banana peel: a potential biosorbent for removal of cadmium ions from aqueous solution","author":"Kaewsarn","year":"2008","journal-title":"Proceedings of the 18th Thailand Chem. Eng. Appl. Chem. Conf."},{"issue":"1","key":"10.1016\/j.fsi.2022.09.029_bib82","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2166\/wst.2003.0049","article-title":"Adsorption of heavy metals from water using banana and orange peels","volume":"47","author":"Annadurai","year":"2003","journal-title":"Water Sci. Technol."},{"key":"10.1016\/j.fsi.2022.09.029_bib83","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3389\/fmicb.2016.00185","article-title":"Intestinal short chain fatty acids and their link with diet and human health","volume":"7","author":"R\u00edos-Covi\u00e1n","year":"2016","journal-title":"Front. Microbiol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464822005964?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464822005964?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T05:39:19Z","timestamp":1760938759000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464822005964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":83,"alternative-id":["S1050464822005964"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2022.09.029","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antioxidative and immunostimulant potential of fruit derived biomolecules in aquaculture","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2022.09.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}