{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T14:32:54Z","timestamp":1775831574764,"version":"3.50.1"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004539","name":"Kasetsart University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004539","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004195","name":"Ocean University of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004195","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.fsi.2023.108983","type":"journal-article","created":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T11:40:53Z","timestamp":1690976453000},"page":"108983","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Effects of ribonucleotide supplementation in modulating the growth of probiotic Bacillus subtilis and the synergistic benefits for improving the health performance of Asian seabass (Lates calcarifer)"],"prefix":"10.1016","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6975-6089","authenticated-orcid":false,"given":"Jureerat","family":"Saengrung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1782-4079","authenticated-orcid":false,"given":"Anurak","family":"Bunnoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinmei","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8811-0922","authenticated-orcid":false,"given":"Lili","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7255-9426","authenticated-orcid":false,"given":"Ran","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingguo","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0354-6538","authenticated-orcid":false,"given":"Prapansak","family":"Srisapoome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2023.108983_bib1","series-title":"Taxonomy, Identification and Biology of Seabass (Lates calcarifer)","first-page":"38","author":"Mathew","year":"2009"},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib2","doi-asserted-by":"crossref","DOI":"10.1088\/1755-1315\/564\/1\/012011","article-title":"Distribution and characteristics of asian seabass (Lates calcarifer bloch, 1790) in south sulawesi","volume":"564","author":"Irmawati","year":"2020","journal-title":"IOP Conf. Ser. Earth Environ. Sci."},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib3","first-page":"93","article-title":"Growth performance and genetic diversity in four strains of Asian seabass, Lates calcarifer (Bloch, 1790) cultivated in Thailand","volume":"52","author":"Joerakate","year":"2018","journal-title":"Agric. Nat. Resour."},{"key":"10.1016\/j.fsi.2023.108983_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.738151","article-title":"Comparison of growth performance, survival rate and economic efficiency of Asian seabass (Lates calcarifer) intensively cultured in earthen ponds with high densities","volume":"554","author":"Nhan","year":"2022","journal-title":"Aquaculture"},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib5","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/are.12917","article-title":"Susceptibility of freshwater rearing Asian seabass (Lates calcarifer) to pathogenic Streptococcus iniae","volume":"48","author":"Kayansamruaj","year":"2017","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.fsi.2023.108983_bib6","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.fsi.2017.09.025","article-title":"Jerusalem artichoke enriched diet on growth performance, immuno-hematological changes and disease resistance against Aeromonas hydrophila in Asian seabass (Lates calcarifer)","volume":"70","author":"Syed Raffic Ali","year":"2017","journal-title":"Fish Shellfish Immunol."},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib7","doi-asserted-by":"crossref","first-page":"497","DOI":"10.20506\/rst.32.2.2245","article-title":"Bacterial infections from aquatic species: potential for and prevention of contact zoonoses","volume":"32","author":"Haenen","year":"2013","journal-title":"Sci. Technol. Rev."},{"issue":"6","key":"10.1016\/j.fsi.2023.108983_bib8","doi-asserted-by":"crossref","first-page":"158","DOI":"10.3390\/md15060158","article-title":"The rising tide of antimicrobial resistance in aquaculture: sources, sinks and solutions","volume":"15","author":"Watts","year":"2017","journal-title":"Mar. Drugs"},{"issue":"3","key":"10.1016\/j.fsi.2023.108983_bib9","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s10499-020-00509-0","article-title":"The exploitation of probiotics, prebiotics and synbiotics in aquaculture: present study, limitations and future directions: a review","volume":"28","author":"Amenyogbe","year":"2020","journal-title":"Aquacult. Int."},{"issue":"6","key":"10.1016\/j.fsi.2023.108983_bib10","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1093\/jn\/125.6.1401","article-title":"Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics","volume":"125","author":"Gibson","year":"1995","journal-title":"J. Nutr."},{"key":"10.1016\/j.fsi.2023.108983_bib11","series-title":"Encyclopedia of Food and Health","first-page":"790","article-title":"Single cell proteins","author":"Nalage","year":"2016"},{"key":"10.1016\/j.fsi.2023.108983_bib12","series-title":"Encyclopedia of Human Nutrition","first-page":"260","article-title":"Nucleic acids","author":"Carrey","year":"2005"},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib13","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1017\/S0954422410000326","article-title":"The role of dietary nucleotides in single-stomached animals","volume":"24","author":"Sauer","year":"2011","journal-title":"Nutr. Res. Rev."},{"issue":"11","key":"10.1016\/j.fsi.2023.108983_bib14","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1042\/BCJ20160510","article-title":"Introduction to the human gut microbiota","volume":"474","author":"Thursby","year":"2017","journal-title":"Biochem. J."},{"issue":"4","key":"10.1016\/j.fsi.2023.108983_bib15","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1128\/AEM.02026-07","article-title":"Utilization of DNA as a sole source of phosphorus, carbon, and energy by Shewanella spp.: Ecological and physiological implications for dissimilatory metal reduction","volume":"74","author":"Pinchuk","year":"2008","journal-title":"Appl. Environ. Microbiol."},{"issue":"6","key":"10.1016\/j.fsi.2023.108983_bib16","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1111\/j.1462-2920.2010.02208.x","article-title":"Pseudomonas aeruginosa produces an extracellular deoxyribonuclease that is required for utilization of DNA as a nutrient source","volume":"12","author":"Mulcahy","year":"2010","journal-title":"Environ. Microbiol."},{"issue":"3","key":"10.1016\/j.fsi.2023.108983_bib17","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/mmi.13128","article-title":"Vibrio cholerae phosphatases required for the utilization of nucleotides and extracellular DNA as phosphate sources","volume":"99","author":"McDonough","year":"2015","journal-title":"Mol. Microbiol."},{"issue":"5","key":"10.1016\/j.fsi.2023.108983_bib18","first-page":"52","article-title":"A review: application of probiotics in aquaculture","volume":"4","author":"Subedi","year":"2020","journal-title":"Int. J. Forest. Animal Fish. Res."},{"key":"10.1016\/j.fsi.2023.108983_bib19","series-title":"Encyclopedia of Microbiology","first-page":"45","article-title":"Bacillus subtilis","author":"Piggot","year":"2009"},{"issue":"3","key":"10.1016\/j.fsi.2023.108983_bib20","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1080\/23308249.2019.1597010","article-title":"Genus Bacillus, promising probiotics in aquaculture: aquatic animal origin, bio-active components, bioremediation and efficacy in fish and shellfish","volume":"27","author":"Soltani","year":"2019","journal-title":"Rev. Fish. Sci. Aquac."},{"issue":"5","key":"10.1016\/j.fsi.2023.108983_bib21","doi-asserted-by":"crossref","first-page":"273","DOI":"10.3390\/fishes7050273","article-title":"Effects of dietary supplementation with probiotics and prebiotics on growth, physiological condition, and resistance to pathogens challenge in Nile tilapia (Oreochromis niloticus)","volume":"7","author":"S\u00eerbu","year":"2022","journal-title":"Fishes"},{"key":"10.1016\/j.fsi.2023.108983_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.653025","article-title":"Mechanisms used by probiotics to confer pathogen resistance to teleost fish","volume":"12","author":"Sim\u00f3n","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2023.108983_bib23","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.fsi.2022.03.040","article-title":"Mucosal and systemic immune effects of Bacillus subtilis in rainbow trout (Oncorhynchus mykiss)","volume":"124","author":"Docando","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.108983_bib24","article-title":"Dietary mixed Bacillus strains promoted the growth indices, enzymatic profile, intestinal immunity, and liver and intestinal histomorphology of Nile tilapia, Oreochromis niloticus","volume":"27","author":"El-Son","year":"2022","journal-title":"Aquac. Rep."},{"key":"10.1016\/j.fsi.2023.108983_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.737794","article-title":"Synbiotic application to enhance growth, immune system, and disease resistance toward bacterial infection in catfish (Clarias gariepinus)","volume":"549","author":"Hardi","year":"2022","journal-title":"Aquaculture"},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib26","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.livsci.2010.06.053","article-title":"Nucleotides modify growth of selected intestinal bacteria in vitro","volume":"133","author":"Sauer","year":"2010","journal-title":"Livest. Sci."},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib27","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10973-010-1121-1","article-title":"Thermokinetic responses of the metabolic activity of Staphylococcus lentus cultivated in a glucose limited mineral salt medium","volume":"104","author":"Sekar","year":"2011","journal-title":"J. Therm. Anal. Calorim."},{"key":"10.1016\/j.fsi.2023.108983_bib28","series-title":"American Water Work Association and Water Environment Federation (APHA, AWWA and WEF). Standard Method for the Examination of Water and Wastewater","year":"2017"},{"key":"10.1016\/j.fsi.2023.108983_bib29","first-page":"77","article-title":"Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g","volume":"97","author":"B\u00f6yum","year":"1968","journal-title":"Scand. J. Clin. Lab. Invest. Suppl."},{"issue":"12","key":"10.1016\/j.fsi.2023.108983_bib30","doi-asserted-by":"crossref","first-page":"613","DOI":"10.3390\/microorganisms7120613","article-title":"Probiotic effects of a novel strain, Acinetobacter KU011TH, on the growth performance, immune responses, and resistance against Aeromonas hydrophila of bighead catfish (Clarias macrocephalus G\u00fcnther, 1864)","volume":"7","author":"Bunnoy","year":"2019","journal-title":"Microorganisms"},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib31","first-page":"309","article-title":"Cell damage and dye reduction in the quantitative nitroblue tetrazolium (NBT) test","volume":"19","author":"Segal","year":"1975","journal-title":"Clin. Exp. Immunol."},{"issue":"6","key":"10.1016\/j.fsi.2023.108983_bib32","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1248\/cpb.40.1523","article-title":"Colorimetric assay for lysozyme using Micrococcus luteus labeled with a blue dye, remazol brilliant blue R, as a substrate","volume":"40","author":"Ito","year":"1992","journal-title":"Chem. Pharm. Bull."},{"issue":"4","key":"10.1016\/j.fsi.2023.108983_bib33","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2023.108983_bib34","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot4986","article-title":"Hematoxylin and eosin staining of tissue and cell sections","author":"Fischer","year":"2008","journal-title":"Cold Spring Harb. Protoc."},{"issue":"5","key":"10.1016\/j.fsi.2023.108983_bib35","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1186\/cc2955","article-title":"Statistics review 12: survival analysis","volume":"8","author":"Bewick","year":"2004","journal-title":"Crit. Care"},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib36","first-page":"1","article-title":"Dietary administration of Lactobacillus plantarum enhanced growth performance and innate immune response of Siberian sturgeon, Acipenser baerii, Probiotics Antimicrob","volume":"8","author":"Pourgholam","year":"2016","journal-title":"Proteins"},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib37","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1111\/raq.12370","article-title":"Recent advances of nucleotide nutrition research in aquaculture: a review","volume":"12","author":"Hossain","year":"2020","journal-title":"Rev. Aquacult."},{"key":"10.1016\/j.fsi.2023.108983_bib38","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.3389\/fmicb.2017.01390","article-title":"Mechanisms and regulation of extracellular DNA release and its biological roles in microbial communities","volume":"8","author":"Ib\u00e1\u00f1ez de Aldecoa","year":"2017","journal-title":"Front. Microbiol."},{"issue":"3","key":"10.1016\/j.fsi.2023.108983_bib39","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/mmi.13128","article-title":"Vibrio cholerae phosphatases required for the utilization of nucleotides and extracellular DNA as phosphate sources","volume":"99","author":"McDonough","year":"2016","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.fsi.2023.108983_bib40","article-title":"Escherichia coli can eat DNA as an excellent nitrogen source to grow quickly","volume":"13","author":"Huang","year":"2022","journal-title":"Front. Microbiol."},{"issue":"6","key":"10.1016\/j.fsi.2023.108983_bib41","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3390\/nu2060611","article-title":"The role of functional foods, nutraceuticals, and food supplements in intestinal health","volume":"2","author":"Cencic","year":"2010","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.fsi.2023.108983_bib42","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1111\/anu.12463","article-title":"Inosine supplementation effectively provokes the growth, immune response, oxidative stress resistance and intestinal morphology of juvenile red sea bream, Pagrus major","volume":"23","author":"Hossain","year":"2017","journal-title":"Aquacult. Nutr."},{"key":"10.1016\/j.fsi.2023.108983_bib43","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.aqrep.2018.03.003","article-title":"Modulation of growth performance, immunological responses and disease resistance of juvenile Nile tilapia (Oreochromis niloticus) (Linnaeus, 1758) by supplementing dietary inosine monophosphate","volume":"10","author":"Kader","year":"2018","journal-title":"Aquac. Rep."},{"key":"10.1016\/j.fsi.2023.108983_bib44","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.aquaculture.2016.11.020","article-title":"Effects of dietary administration of inosine on growth, immune response, oxidative stress and gut morphology of juvenile amberjack","volume":"468","author":"Hossain","year":"2017","journal-title":"Seriola Dumerili, Aquac."},{"key":"10.1016\/j.fsi.2023.108983_bib45","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.3168\/jds.2007-0751","article-title":"Effects of nucleotide supplementation in milk replacer on small intestinal absorptive capacity in dairy calves","volume":"91","author":"Kehoe","year":"2008","journal-title":"J. Dairy Sci."},{"issue":"4","key":"10.1016\/j.fsi.2023.108983_bib46","first-page":"621","article-title":"Supplementation of nucleotides to enhance performance and immune responses of Asian seabass, Jordan","volume":"14","author":"Hastuti","year":"2021","journal-title":"J. Biol. Sci."},{"issue":"8","key":"10.1016\/j.fsi.2023.108983_bib47","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1046\/j.1365-2761.2001.00314.x","article-title":"Immunostimulant effects of nucleotide isolated from yeast RNA on carp, Cyprinus carpio","volume":"24","author":"Sakai","year":"2001","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2023.108983_bib48","first-page":"1","article-title":"Use of immunostimulants and nucleotides in aquaculture: a review","volume":"2","author":"Ring\u00f8","year":"2012","journal-title":"J. Marine Sci. Res. Dev."},{"key":"10.1016\/j.fsi.2023.108983_bib49","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0044-8486(01)00577-4","article-title":"Dietary nucleotides: a novel supplement in fish feeds. 1. Effects on resistance to disease in salmonids","volume":"199","author":"Burrells","year":"2001","journal-title":"Aquaculture"},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib50","first-page":"72","article-title":"Histological alteration in Asian seabass (Lates calcarifer) during exposed to non-essential and essential elements","volume":"9","author":"Thanomsit","year":"2016","journal-title":"EnvironmentAsia"},{"issue":"3","key":"10.1016\/j.fsi.2023.108983_bib51","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.2478\/aoas-2022-0006","article-title":"The multi-enzymes and probiotics mixture improves the growth performance, digestibility, intestinal health, and immune response of Siberian sturgeon","volume":"22","author":"Shekarabi","year":"2022","journal-title":"Ann. Anim. Sci."},{"key":"10.1016\/j.fsi.2023.108983_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.anifeedsci.2021.114892","article-title":"Synergistic effects of Bacillus pumilus and exogenous protease on Nile tilapia (Oreochromis niloticus) growth, gut microbes, immune response and gene expression fed plant protein diet","volume":"275","author":"Hassaan","year":"2021","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.fsi.2023.108983_bib53","first-page":"535","article-title":"Evaluation of azotobacter and azospirillum biofertilizers as a probiotics in Oreochromis niloticus aquaculture","volume":"6","author":"Ali","year":"2011","journal-title":"J. Fish. Aquat. Sci."},{"issue":"12","key":"10.1016\/j.fsi.2023.108983_bib54","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.3390\/ani12121586","article-title":"Immune modulation ability of hepcidin from teleost fish","volume":"12","author":"\u00c1lvarez","year":"2022","journal-title":"Animals (Basel)"},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib55","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3390\/molecules27020555","article-title":"Exploring the immune-boosting functions of vitamins and minerals as nutritional food bioactive compounds: a comprehensive review","volume":"27","author":"Mitra","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.fsi.2023.108983_bib56","doi-asserted-by":"crossref","first-page":"309","DOI":"10.3389\/fcimb.2020.00309","article-title":"C-type lectin receptors in host defense against bacterial pathogens","volume":"10","author":"Mnich","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"9","key":"10.1016\/j.fsi.2023.108983_bib57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006512","article-title":"From bacterial killing to immune modulation: recent insights into the functions of lysozyme","volume":"13","author":"Ragland","year":"2017","journal-title":"PLoS Pathog."},{"issue":"7","key":"10.1016\/j.fsi.2023.108983_bib58","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0022038","article-title":"Modelling the role of the Hsp70\/Hsp90 system in the maintenance of protein homeostasis","volume":"6","author":"Proctor","year":"2011","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib59","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s10811-021-02377-4","article-title":"Health status in gilthead seabream (Sparus aurata) juveniles fed diets devoid of fishmeal and supplemented with Phaeodactylum tricornutum","volume":"33","author":"Reis","year":"2021","journal-title":"J. Appl. Phycol."},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib60","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1111\/j.1439-0426.2011.01676.x","article-title":"Dietary glutamine supplementation improves tissue antioxidant status and serum non-specific immunity of juvenile hybrid sturgeon (Acipenser schrenckii \u2640 \u00d7 Huso dauricus\u2642)","volume":"27","author":"Zhu","year":"2011","journal-title":"J. Appl. Ichthyol."},{"issue":"2","key":"10.1016\/j.fsi.2023.108983_bib61","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s10695-018-0595-9","article-title":"Dietary supplementation of Streptococcus faecalis benefits the feed utilization, antioxidant capability, innate immunity, and disease resistance of blunt snout bream (Megalobrama amblycephala)","volume":"45","author":"Zhong","year":"2019","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.fsi.2023.108983_bib62","first-page":"39","article-title":"Effects of dietary nucleotides on survival and activites of serum complements C3 and C4 of rainbow trout (Oncorhynchus mykiss) challenged with Streptococcus iniae","volume":"2","author":"Ahmad","year":"2011","journal-title":"J. Oceanogr."},{"issue":"4","key":"10.1016\/j.fsi.2023.108983_bib63","first-page":"2024","article-title":"Efficacy of dietary supplementation of Bacillus licheniformis and Bacillus subtilis probiotics and Saccharomyces cerevisiae (yeast) on the hematological, immune response, and biochemical features of Persian sturgeon (Acipenser persicus) fingerlings, Iran","volume":"19","author":"Darafsh","year":"2020","journal-title":"J. Fish. Sci."},{"issue":"3","key":"10.1016\/j.fsi.2023.108983_bib64","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s12263-011-0218-x","article-title":"The immunomodulatory properties of probiotic microorganisms beyond their viability (ghost probiotics: proposal of paraprobiotic concept)","volume":"6","author":"Taverniti","year":"2011","journal-title":"Genes Nutr."},{"issue":"5","key":"10.1016\/j.fsi.2023.108983_bib65","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.fsi.2005.03.008","article-title":"The use of immunostimulants in fish larval aquaculture","volume":"19","author":"Bricknell","year":"2005","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib66","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1038\/s41598-022-05779-7","article-title":"Influence of extracellular protein isolated from fish gut associated bacteria as an enhancer of growth and innate immune system in Mugil cephalus","volume":"12","author":"Thirunavukkarasu","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fsi.2023.108983_bib67","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s12562-019-01394-0","article-title":"Efficacy of Bacillus spp. isolated from Nile tilapia Oreochromis niloticus Linn. on its growth and immunity, and control of pathogenic bacteria","volume":"86","author":"Sookchaiyaporn","year":"2020","journal-title":"Fish. Sci."},{"issue":"3","key":"10.1016\/j.fsi.2023.108983_bib68","doi-asserted-by":"crossref","first-page":"525","DOI":"10.3390\/biology4030525","article-title":"The mucosal immune system of teleost fish","volume":"4","author":"Salinas","year":"2015","journal-title":"Biology"},{"key":"10.1016\/j.fsi.2023.108983_bib69","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.02292","article-title":"A comparison of the innate and adaptive immune systems in cartilaginous fish, ray-finned fish, and lobe-finned fish","volume":"10","author":"Smith","year":"2019","journal-title":"Front. Immunol."},{"issue":"1\u20132","key":"10.1016\/j.fsi.2023.108983_bib70","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.fsi.2008.03.013","article-title":"Studies on Bacillus subtilis and Lactobacillus acidophilus, as potential probiotics, on the immune response and resistance of Tilapia nilotica (Oreochromis niloticus) to challenge infections","volume":"25","author":"Aly","year":"2008","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib71","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-52693-6","article-title":"Protective effects of seaweed supplemented diet on antioxidant and immune responses in European seabass (Dicentrarchus labrax) subjected to bacterial infection","volume":"9","author":"Peixoto","year":"2019","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.fsi.2023.108983_bib72","doi-asserted-by":"crossref","DOI":"10.1088\/1755-1315\/521\/1\/012007","article-title":"The growth performance and survival rate of catfish (Clarias sp.) that given probiotic controlling nitrogen","volume":"521","author":"Yosmaniar","year":"2020","journal-title":"IOP Conf. Ser. Earth Environ. Sci."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464823004692?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464823004692?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T05:49:02Z","timestamp":1760939342000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464823004692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":72,"alternative-id":["S1050464823004692"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2023.108983","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of ribonucleotide supplementation in modulating the growth of probiotic Bacillus subtilis and the synergistic benefits for improving the health performance of Asian seabass (Lates calcarifer)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2023.108983","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108983"}}