{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T04:22:56Z","timestamp":1783225376076,"version":"3.54.6"},"reference-count":89,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.fsi.2023.109177","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T11:42:02Z","timestamp":1697629322000},"page":"109177","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Effects of the combination of chitosan and Acinetobacter KU011TH on the growth and health performances and disease resistance of juvenile hybrid catfish (Clarias gariepinus \u00d7 C. macrocephalus)"],"prefix":"10.1016","volume":"142","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2425-9972","authenticated-orcid":false,"given":"Pisey","family":"Say","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukkrit","family":"Nimitkul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1782-4079","authenticated-orcid":false,"given":"Anurak","family":"Bunnoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uthairat","family":"Na-Nakorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0354-6538","authenticated-orcid":false,"given":"Prapansak","family":"Srisapoome","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2023.109177_bib1","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.fsi.2021.08.011","article-title":"Growth hormone secretagogue peptide-6 enhances oreochromicins transcription and antimicrobial activity in tilapia (Oreochromis sp.)","volume":"119","author":"Hern\u00e1ndez","year":"2021","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3390\/fishes7010031","article-title":"Feed supplementation with the GHRP-6 peptide, a ghrelin analog, improves feed intake, growth performance and aerobic metabolism in the gilthead sea bream Sparus aurata","volume":"7","author":"Rodr\u00edguez-Viera","year":"2022","journal-title":"Fishes"},{"key":"10.1016\/j.fsi.2023.109177_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.789573","article-title":"Genome-wide SNP analysis of hybrid clariid fish reflects the existence of polygenic sex-determination in the lineage","volume":"13","author":"Nguyen","year":"2022","journal-title":"Front. Genet."},{"issue":"1\u20134","key":"10.1016\/j.fsi.2023.109177_bib4","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.aquaculture.2003.08.020","article-title":"Genetic impacts of hybrid catfish farming (Clarias macrocephalus \u00d7 C. gariepinus) on native catfish populations in central Thailand","volume":"235","author":"Senanan","year":"2004","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2023.109177_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.738371","article-title":"Isolation and characterization of Aeromonas hydrophila-specific lytic bacteriophages","volume":"558","author":"Ture","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2023.109177_bib6","doi-asserted-by":"crossref","first-page":"508","DOI":"10.3389\/fphys.2019.00508","article-title":"Dietary tryptophan induces opposite health-related responses in the Senegalese sole (Solea senegalensis) reared at low or high stocking densities with implications in disease resistance","volume":"10","author":"Azeredo","year":"2019","journal-title":"Front. Physiol."},{"issue":"9","key":"10.1016\/j.fsi.2023.109177_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0203641","article-title":"Extended antibiotic treatment in salmon farms select multiresistant gut bacteria with a high prevalence of antibiotic resistance genes","volume":"13","author":"Higuera-Llant\u00e9n","year":"2018","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.fsi.2023.109177_bib8","doi-asserted-by":"crossref","first-page":"193","DOI":"10.7120\/09627286.27.3.193","article-title":"A review of factors affecting the welfare of Atlantic salmon (Salmo salar)","volume":"27","author":"Santurtun","year":"2018","journal-title":"Anim. Welf."},{"key":"10.1016\/j.fsi.2023.109177_bib9","doi-asserted-by":"crossref","unstructured":"T. Khunrang, C. Pooljun, S. Wutisutimeethavee, S. Direkbusarakom, Effects of mixed probiotic (Lactobacillus sp. and Saccharomyces cerevisiae) on the growth performance and immune gene expression of tilapia (Oreochromis niloticus) after Streptococcus agalactiae vaccination. Aquacult. Res. 52(8), 3882-3889 https:\/\/doi.org\/10.1111\/are.15232..","DOI":"10.1111\/are.15232"},{"issue":"1870","key":"10.1016\/j.fsi.2023.109177_bib10","first-page":"1","article-title":"Aquaculture at the crossroads of global warming and antimicrobial resistance","volume":"11","author":"Reverter","year":"2020","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.fsi.2023.109177_bib11","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3390\/pathogens10020185","article-title":"Antiparasitic and antibacterial functionality of essential oils: an alternative approach for sustainable aquaculture","volume":"10","author":"Dawood","year":"2021","journal-title":"Pathogens"},{"issue":"6","key":"10.1016\/j.fsi.2023.109177_bib12","doi-asserted-by":"crossref","first-page":"180","DOI":"10.3390\/microorganisms7060180","article-title":"Antibiotic pollution in the environment: from microbial ecology to public policy","volume":"7","author":"Kraemer","year":"2019","journal-title":"Microorganisms"},{"issue":"11","key":"10.1016\/j.fsi.2023.109177_bib13","doi-asserted-by":"crossref","first-page":"549","DOI":"10.3390\/microorganisms7110549","article-title":"Acinetobacter strain KUO11TH, a unique organism related to Acinetobacter pittii and isolated from the skin mucus of healthy bighead catfish and its efficacy against several fish pathogens","volume":"7","author":"Bunnoy","year":"2019","journal-title":"Microorganisms"},{"key":"10.1016\/j.fsi.2023.109177_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.736345","article-title":"Feed supplementation with quorum quenching probiotics with anti-virulence potential improved innate immune responses, antioxidant capacity and disease resistance in Asian seabass (Lates calcarifer)","volume":"535","author":"Ghanei-Motlagh","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2023.109177_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fsi.2021.04.012","article-title":"Short- and short-term probiotic effects of Enterococcus hirae isolated from fermented vegetable wastes on the growth, immune responses, and disease resistance of hybrid catfish (Clarias gariepinus \u00d7 Clarias macrocephalus)","volume":"114","author":"Hamid","year":"2021","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib16","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.fsi.2022.07.017","article-title":"Potential synbiotic effects of a Bacillus mixture and chitosan on growth, immune responses and VP(AHPND) resistance in Pacific white shrimp (Litopenaeus vannamei, Boone, 1931)","volume":"127","author":"Kewcharoen","year":"2022","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib17","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.fsi.2015.02.023","article-title":"Prospects of host-associated microorganisms in fish and penaeids as probiotics with immunomodulatory functions","volume":"45","author":"Lazado","year":"2015","journal-title":"Fish Shellfish Immunol."},{"issue":"5","key":"10.1016\/j.fsi.2023.109177_bib18","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.fsi.2005.03.008","article-title":"The use of immunostimulants in fish larval aquaculture","volume":"19","author":"Bricknell","year":"2005","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib19","article-title":"Oral administration of nanopeptide CMCS-20H conspicuously boosts immunity and precautionary effect against bacterial infection in fish","volume":"12","author":"Huo","year":"2021","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.fsi.2023.109177_bib20","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1016\/j.fsi.2013.09.039","article-title":"Dietary synbiotic application modulates Atlantic salmon (Salmo salar) intestinal microbial communities and intestinal immunity","volume":"35","author":"Abid","year":"2013","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib21","first-page":"172","article-title":"Synbiotic effects of Aspergillus oryzae and \u03b2-glucan on growth and oxidative and immune responses of Nile tilapia, Oreochromis niloticus. Probiotics Antimicrob","volume":"12","author":"Dawood","year":"2020","journal-title":"Proteins"},{"key":"10.1016\/j.fsi.2023.109177_bib22","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.fsi.2021.02.011","article-title":"Effects of dietary synbiotics supplementation methods on growth, intestinal health, non-specific immunity and disease resistance of Pacific white shrimp, Litopenaeus vannamei","volume":"112","author":"Yao","year":"2021","journal-title":"Fish Shellfish Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2023.109177_bib23","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s10499-020-00509-0","article-title":"The exploitation of probiotics, prebiotics and synbiotics in aquaculture: present study, limitations and future directions: a review","volume":"28","author":"Amenyogbe","year":"2020","journal-title":"Aquacult. Int."},{"issue":"3","key":"10.1016\/j.fsi.2023.109177_bib24","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1099\/ijsem.0.002608","article-title":"Acinetobacter piscicola sp. nov., isolated from diseased farmed Murray cod (Maccullochella peelii peelii)","volume":"68","author":"Liu","year":"2018","journal-title":"Int. J. Syst. Evol. Microbiol."},{"issue":"4","key":"10.1016\/j.fsi.2023.109177_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.syapm.2020.126092","article-title":"Characterization of Acinetobacter chengduensis sp. nov., isolated from hospital sewage and capable of acquisition of carbapenem resistance genes","volume":"43","author":"Qin","year":"2020","journal-title":"Syst. Appl. Microbiol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib26","doi-asserted-by":"crossref","first-page":"12","DOI":"10.31058\/j.nano.2018.11002","article-title":"Effects of chitosan and chitosan nanoparticles on water quality, growth performance, survival rate and meat quality of the African catfish (Clarias gariepinus)","volume":"1","author":"Udo","year":"2018","journal-title":"Nanoscience"},{"issue":"3","key":"10.1016\/j.fsi.2023.109177_bib27","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1007\/s10924-016-0865-5","article-title":"Chitin and chitosan: structure, properties and applications in biomedical engineering","volume":"25","author":"Islam","year":"2016","journal-title":"J. Polym. Environ."},{"issue":"12","key":"10.1016\/j.fsi.2023.109177_bib28","doi-asserted-by":"crossref","first-page":"613","DOI":"10.3390\/microorganisms7120613","article-title":"Probiotic effects of a novel strain, Acinetobacter KU011TH, on the growth performance, immune responses, and resistance against Aeromonas hydrophila of bighead catfish (Clarias macrocephalus Gunther, 1864)","volume":"7","author":"Bunnoy","year":"2019","journal-title":"Microorganisms"},{"issue":"2","key":"10.1016\/j.fsi.2023.109177_bib29","first-page":"309","article-title":"Cell damage and dye reduction in the quantitative nitroblue tetrazolium (NBT) test","volume":"19","author":"Segal","year":"1975","journal-title":"Clin. Exp. Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib30","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.fsi.2010.09.012","article-title":"Altered hematological and immunological parameters in silver catfish (Rhamdia quelen) following short term exposure to sublethal concentration of glyphosate","volume":"30","author":"Kreutz","year":"2011","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib31","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.dci.2013.01.010","article-title":"Enzyme characterisation and gene expression profiling of Atlantic salmon chicken- and goose-type lysozymes","volume":"40","author":"Myrnes","year":"2013","journal-title":"Dev. Comp. Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2023.109177_bib32","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/0165-2427(94)05430-Z","article-title":"Natural hemolytic and bactericidal activities of sea bream Sparus aurata serum are effected by the alternative complement pathway","volume":"45","author":"Oriol Sunyer","year":"1995","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib33","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s13205-018-1535-1","article-title":"Antibacterial activity and action mechanism of questin from marine Aspergillus flavipes HN4-13 against aquatic pathogen Vibrio harveyi","volume":"9","author":"Guo","year":"2019","journal-title":"3 Biotech"},{"issue":"14","key":"10.1016\/j.fsi.2023.109177_bib34","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1111\/j.1365-2109.2009.02265.x","article-title":"Effects of the probiotic, Lactobacillus acidophilus, on the growth performance, haematology parameters and immunoglobulin concentration in African catfish (Clarias gariepinus, Burchell 1822) fingerling","volume":"40","author":"Al-Dohail","year":"2009","journal-title":"Aquacult. Res."},{"issue":"4","key":"10.1016\/j.fsi.2023.109177_bib35","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2-\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2023.109177_bib36","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.fsi.2021.05.003","article-title":"Overview of the latest developments in the role of probiotics, prebiotics and synbiotics in shrimp aquaculture","volume":"114","author":"Butt","year":"2021","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib37","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.fsi.2021.12.037","article-title":"Probiotics, prebiotics and synbiotics improved the functionality of aquafeed: upgrading growth, reproduction, immunity and disease resistance in fish","volume":"120","author":"Rohani","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2020.115941","article-title":"Production of prebiotic chitooligosaccharide and its nano\/microencapsulation for the production of functional yoghurt","volume":"234","author":"Ismail","year":"2020","journal-title":"Carbohydr. Polym."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib39","doi-asserted-by":"crossref","first-page":"25","DOI":"10.14710\/jkt.v24i1.9925","article-title":"Potency of chitosan and chitooligochitosan (COS) as prebiotics for Streptococcus thermophillus and Lactobacillus bulgaricus probiotics","volume":"24","author":"Yudiati","year":"2021","journal-title":"J. Kelaut. Trop."},{"key":"10.1016\/j.fsi.2023.109177_bib40","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.foodchem.2017.08.041","article-title":"Chitosan from shrimp shells: a renewable sorbent applied to the clean-up step of the QuEChERS method in order to determine multi-residues of veterinary drugs in different types of milk","volume":"240","author":"Arias","year":"2018","journal-title":"Food Chem."},{"key":"10.1016\/j.fsi.2023.109177_bib41","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.procbio.2020.04.035","article-title":"Assessing the effect of chitosan on pesticide removal in grape juice during clarification by gas chromatography with tandem mass spectrometry","volume":"94","author":"Venkatachalapathy","year":"2020","journal-title":"Process Biochem."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib42","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/raq.12081","article-title":"Transcriptional stress responses to environmental and husbandry stressors in aquaculture species","volume":"8","author":"Eissa","year":"2016","journal-title":"Rev. Aquacult."},{"issue":"11","key":"10.1016\/j.fsi.2023.109177_bib43","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.tim.2018.05.002","article-title":"Biological approaches for disease control in aquaculture: advantages, limitations and challenges","volume":"26","author":"P\u00e9rez-S\u00e1nchez","year":"2018","journal-title":"Trends Microbiol."},{"issue":"4","key":"10.1016\/j.fsi.2023.109177_bib44","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1007\/s12639-017-0938-y","article-title":"An overall estimation of losses caused by diseases in the Brazilian fish farms","volume":"41","author":"Tavares-Dias","year":"2017","journal-title":"J. Parasit. Dis."},{"key":"10.1016\/j.fsi.2023.109177_bib45","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.3389\/fphys.2018.01113","article-title":"A review of molecular responses of catfish to bacterial diseases and abiotic stresses","volume":"9","author":"Zhou","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.fsi.2023.109177_bib46","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.3390\/microorganisms11071807","article-title":"Long-term application of a synbiotic chitosan and Acinetobacter KU011TH mixture on the growth performance, health status, and disease resistance of hybrid catfish (Clarias gariepinus \u00d7 C. macrocephalus) during winter","volume":"11","author":"Say","year":"2023","journal-title":"Microorganisms"},{"issue":"7","key":"10.1016\/j.fsi.2023.109177_bib47","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1111\/are.13701","article-title":"Effects of synbiotic containing Lactobacillus plantarum 7\u201340 and galactooligosaccharide on the growth performance of white shrimp, Litopenaeus vannamei","volume":"49","author":"Huynh","year":"2018","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.fsi.2023.109177_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.737514","article-title":"Probiotics, prebiotics, and synbiotics used to control vibriosis in fish: a review","volume":"547","author":"Yilmaz","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2023.109177_bib49","series-title":"Fish Mucosal Immunity: Skin, Mucosal Health in Aquaculture","first-page":"67","author":"Esteban","year":"2015"},{"key":"10.1016\/j.fsi.2023.109177_bib50","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.2147\/JIR.S318327","article-title":"Role of goblet cells in intestinal barrier and mucosal immunity","volume":"14","author":"Yang","year":"2021","journal-title":"J. Inflamm. Res."},{"issue":"32","key":"10.1016\/j.fsi.2023.109177_bib51","doi-asserted-by":"crossref","first-page":"13097","DOI":"10.1073\/pnas.1304319110","article-title":"Teleost skin, an ancient mucosal surface that elicits gut-like immune responses","volume":"110","author":"Xu","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.fsi.2023.109177_bib52","doi-asserted-by":"crossref","first-page":"361","DOI":"10.21608\/ejabf.2020.114402","article-title":"Epidermal mucus as a potential biological matrix for fish health analysis","volume":"24","author":"Santoso","year":"2020","journal-title":"Egypt. J. Aquat. Biol. & Fish"},{"issue":"2","key":"10.1016\/j.fsi.2023.109177_bib53","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.fsi.2014.01.001","article-title":"Comparative skin mucus and serum humoral defence mechanisms in the teleost gilthead seabream (Sparus aurata)","volume":"36","author":"Guardiola","year":"2014","journal-title":"Fish Shellfish Immunol."},{"issue":"2","key":"10.1016\/j.fsi.2023.109177_bib54","first-page":"72","article-title":"Epidermal mucus, a major determinant in fish health: a review. Iran","volume":"19","author":"Dash","year":"2018","journal-title":"J. Vet. Res."},{"key":"10.1016\/j.fsi.2023.109177_bib55","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/s40257-017-0300-2","article-title":"Probiotics, prebiotics, and synbiotics for the treatment and prevention of adult dermatological diseases","volume":"18","author":"Notay","year":"2017","journal-title":"Am. J. Clin. Dermatol."},{"issue":"1625","key":"10.1016\/j.fsi.2023.109177_bib56","first-page":"2611","article-title":"Epidermal \u2018alarm substance\u2019 cells of fishes maintained by non-alarm functions: possible defence against pathogens, parasites and UVB radiation","volume":"274","author":"Chivers","year":"2007","journal-title":"Proc. Biol. Sci."},{"issue":"2","key":"10.1016\/j.fsi.2023.109177_bib57","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3920\/BM2013.0040","article-title":"Impact of prebiotics and probiotics on skin health","volume":"5","author":"Al-Ghazzewi","year":"2014","journal-title":"Benef. Microbes"},{"key":"10.1016\/j.fsi.2023.109177_bib58","series-title":"International Review of Cell and Molecular Biology","first-page":"133","article-title":"Roles of substance P and ATP in the subepithelial fibroblasts of rat intestinal villi","author":"Furuya","year":"2013"},{"key":"10.1016\/j.fsi.2023.109177_bib59","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.fsi.2019.12.046","article-title":"Effects of three host-associated Bacillus species on mucosal immunity and gut health of Nile tilapia, Oreochromis niloticus and its resistance against Aeromonas hydrophila infection","volume":"97","author":"Kuebutornye","year":"2020","journal-title":"Fish Shellfish Immunol."},{"issue":"6","key":"10.1016\/j.fsi.2023.109177_bib60","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1038\/s41385-018-0039-y","article-title":"Goblet cells: multifaceted players in immunity at mucosal surfaces","volume":"11","author":"Knoop","year":"2018","journal-title":"Mucosal Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib61","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.aquaculture.2004.09.032","article-title":"The viability of probiotic bacteria as a factor influencing the immune response in rainbow trout Oncorhynchus mykiss","volume":"243","author":"Panigrahi","year":"2005","journal-title":"Aquaculture"},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib62","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1574-6968.2009.01887.x","volume":"304","author":"Atassi","year":"2010","journal-title":"FEMS Microbiol. Lett."},{"issue":"4","key":"10.1016\/j.fsi.2023.109177_bib63","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1128\/AEM.01820-10","article-title":"Novel probiotic Bifidobacterium bifidum CECT 7366 strain active against the pathogenic bacterium Helicobacter pylori","volume":"77","author":"Chenoll","year":"2011","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.fsi.2023.109177_bib64","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.695973","article-title":"Phytogenic bioactive compounds shape fish mucosal immunity","volume":"12","author":"Firmino","year":"2021","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib65","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s12602-014-9180-4","article-title":"Effect of a probiotic containing Bacillus licheniformis and Bacillus subtilis and ferroin solution on growth performance, body composition and haematological parameters in Kutum (Rutilus frisii kutum) fry","volume":"7","author":"Azarin","year":"2015","journal-title":"Probiotics Antimicrob. Proteins"},{"issue":"4","key":"10.1016\/j.fsi.2023.109177_bib66","first-page":"279","article-title":"Effect of probiotics on the haematological parameters of Indian magur (Clarius batrachus L.)","volume":"7","author":"Dahiya","year":"2012","journal-title":"J. Fish. Aquat. Sci."},{"issue":"12","key":"10.1016\/j.fsi.2023.109177_bib67","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.3390\/biology10121236","article-title":"Blood performance: a new formula for fish growth and health","volume":"10","author":"Esmaeili","year":"2021","journal-title":"Biology"},{"issue":"2","key":"10.1016\/j.fsi.2023.109177_bib68","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.fsi.2014.05.025","article-title":"Dietary administration of Bacillus subtilis on hematology and non-specific immunity of Nile tilapia Oreochromis niloticus raised at different stocking densities","volume":"39","author":"Telli","year":"2014","journal-title":"Fish Shellfish Immunol."},{"issue":"8","key":"10.1016\/j.fsi.2023.109177_bib69","doi-asserted-by":"crossref","first-page":"684","DOI":"10.3923\/ajava.2012.684.692","article-title":"Effect of prebiotic supplementation on growth performance and serum biochemical parameters of Kutum (Rutilus frisii kutum) fries","volume":"7","author":"Yousefian","year":"2012","journal-title":"Asian J. Anim. Vet. Adv."},{"key":"10.1016\/j.fsi.2023.109177_bib70","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.nut.2018.07.017","article-title":"Probiotic and synbiotic therapy in the critically ill: state of the art","volume":"59","author":"Davison","year":"2019","journal-title":"Nutrition"},{"key":"10.1016\/j.fsi.2023.109177_bib71","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.fsi.2021.11.028","article-title":"The synergistic effects of plant polysaccharide and Pediococcus acidilactici as a synbiotic additive on growth, antioxidant status, immune response, and resistance of Nile tilapia (Oreochromis niloticus) against Aeromonas hydrophila","volume":"120","author":"Mohammadi","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2021.118334","article-title":"Therapeutic effect and immune mechanism of chitosan-gentamicin conjugate on Pacific white shrimp (Litopenaeus vannamei) infected with Vibrio parahaemolyticus","volume":"269","author":"Liang","year":"2021","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.fsi.2023.109177_bib73","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.fsi.2016.10.011","article-title":"Immune response induced by oral delivery of Bacillus subtilis spores expressing enolase of Clonorchis sinensis in grass carps (Ctenopharyngodon idellus)","volume":"60","author":"Jiang","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib74","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.fsi.2018.11.080","article-title":"TroCCL4, a CC chemokine of Trachinotus ovatus, is involved in the antimicrobial immune response","volume":"86","author":"Sun","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib75","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.fsi.2022.09.002","article-title":"Genome-wide identification, evolutionary analysis, and antimicrobial activity prediction of CC chemokines in allotetraploid common carp, Cyprinus carpio","volume":"130","author":"Qiao","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib76","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.fsi.2022.02.032","article-title":"CC chemokine 1 protein from Cromileptes altivelis (CaCC1) promotes antimicrobial immune defense","volume":"123","author":"Yang","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib77","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.fsi.2018.10.083","article-title":"Molecular characterization and expression analysis of complement component C3 in southern catfish (Silurus meridionalis) and a whole mount in situ hybridization study on its ontogeny","volume":"84","author":"Fu","year":"2019","journal-title":"Fish Shellfish Immunol."},{"issue":"2","key":"10.1016\/j.fsi.2023.109177_bib78","doi-asserted-by":"crossref","first-page":"501","DOI":"10.3390\/ijms21020501","article-title":"Two distinct c-type lysozymes in goldfish: molecular characterization, antimicrobial potential, and transcriptional regulation in response to opposing effects of bacteria\/lipopolysaccharide and dexamethasone\/leptin","volume":"21","author":"Chen","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.fsi.2023.109177_bib79","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s13258-018-0656-6","article-title":"Identification and characterization of a novel goose-type and chicken-type lysozyme genes in Chinese rare minnow (Gobiocypris rarus) with potent antimicrobial activity","volume":"40","author":"Zhang","year":"2018","journal-title":"Genes Genom"},{"key":"10.1016\/j.fsi.2023.109177_bib80","article-title":"Identification and characterization of the c-type lysozyme gene from a marine fish, Bostrychus sinensis","volume":"125","author":"Shen","year":"2021","journal-title":"Dev. Comp. Immunol. Pergamon"},{"key":"10.1016\/j.fsi.2023.109177_bib81","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2022.104412","article-title":"Characterization and functional analysis of a C-type lysozyme gene from obscure puffer Takifugu obscurus","volume":"133","author":"Wang","year":"2022","journal-title":"Dev. Comp. Immunol."},{"issue":"11","key":"10.1016\/j.fsi.2023.109177_bib82","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/j.bcp.2006.04.011","article-title":"NF-\u03baB activation by reactive oxygen species: fifteen years later","volume":"72","author":"Gloire","year":"2006","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.fsi.2023.109177_bib83","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jff.2017.05.036","article-title":"Oral administration of yeast \u03b2-glucan ameliorates inflammation and intestinal barrier in dextran sodium sulfate-induced acute colitis","volume":"35","author":"Han","year":"2017","journal-title":"J. Funct.Foods"},{"issue":"1","key":"10.1016\/j.fsi.2023.109177_bib84","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.fsi.2015.01.038","article-title":"Myeloperoxidase-deficient zebrafish show an augmented inflammatory response to challenge with Candida albicans","volume":"44","author":"Wang","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib85","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.fsi.2019.08.050","article-title":"A bactericidal permeability-increasing protein (BPI) from manila clam Ruditapes philippinarum: investigation on the antibacterial activities and antibacterial action mode","volume":"93","author":"Yang","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2023.109177_bib86","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/2798279","article-title":"Effects of probiotics, prebiotics, and synbiotics as an alternative to antibiotics on growth and blood profile of Nile tilapia (Oreochromis niloticus)","volume":"2023","author":"Munni","year":"2023","journal-title":"Aquacult. Res."},{"key":"10.1016\/j.fsi.2023.109177_bib87","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.737965","article-title":"Synbiotic feed supplementation improves antioxidant response and innate immunity of juvenile barramundi, Lates calcarifer subjected to bacterial infection","volume":"552","author":"Siddik","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2023.109177_bib88","article-title":"Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies","volume":"6","author":"Wu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fsi.2023.109177_bib89","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/24705470221076390","article-title":"The role of lipopolysaccharide-induced cell signalling in chronic inflammation","volume":"6","author":"Page","year":"2022","journal-title":"Chronic Stress"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464823006630?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464823006630?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T05:54:37Z","timestamp":1760939677000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464823006630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":89,"alternative-id":["S1050464823006630"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2023.109177","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of the combination of chitosan and Acinetobacter KU011TH on the growth and health performances and disease resistance of juvenile hybrid catfish (Clarias gariepinus \u00d7 C. macrocephalus)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2023.109177","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109177"}}