{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:24:37Z","timestamp":1792509877345,"version":"4.5.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.fsi.2024.109411","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T12:50:05Z","timestamp":1706619005000},"page":"109411","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Acrylamide exposure induces growth retardation, neurotoxicity, stress, and immune\/antioxidant disruption in Nile tilapia (Oreochromis niloticus): The alleviative effects of Chlorella vulgaris diets"],"prefix":"10.1016","volume":"146","author":[{"given":"Asmaa","family":"Edrees","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nema S.","family":"Shaban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nour El-Houda Y.","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmaa S.A.","family":"Abdel-Daim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed S.","family":"Sobh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rowida E.","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2024.109411_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2023.739803","article-title":"Kidney bean protein hydrolysate as a fish meal replacer: effects on growth, digestive enzymes, metabolic functions, immune-antioxidant parameters and their related gene expression, intestinal and muscular gene expression","author":"Ibrahim","year":"2023","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109411_bib2","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.fsi.2022.11.013","article-title":"Immune-antioxidant trait, growth, splenic cytokines expression, apoptosis, and histopathological alterations of Oreochromis niloticus exposed to sub-lethal copper toxicity and fed thyme and\/or basil essential oils enriched diets","volume":"131","author":"Ahmed","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109411_bib3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3390\/fishes8010015","volume":"8","author":"Ibrahim","year":"2022","journal-title":"Fishes"},{"key":"10.1016\/j.fsi.2024.109411_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jscs.2022.101587","article-title":"Potential hazards and health assessment associated with different water uses in the main industrial cities of Egypt","volume":"27","author":"Mekawi","year":"2023","journal-title":"J. Saudi Chem. Soc."},{"key":"10.1016\/j.fsi.2024.109411_bib5","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.aquaculture.2019.02.050","article-title":"Ameliorative effects of Moringa oleifera seeds and leaves on chlorpyrifos-induced growth retardation, immune suppression, oxidative stress, and DNA damage in Oreochromis niloticus","volume":"505","author":"Ibrahim","year":"2019","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109411_bib6","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3390\/separations10070385","article-title":"Treatment of water and wastewater: challenges and solutions","volume":"10","author":"Mojiri","year":"2023","journal-title":"MDPI, Separations"},{"key":"10.1016\/j.fsi.2024.109411_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2020.111875","article-title":"The adverse effects of acrylamide exposure on the early development of marine medaka (Oryzias melastigma) and its mechanisms","volume":"163","author":"Yue","year":"2021","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.fsi.2024.109411_bib8","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/tox.22863","article-title":"Acrylamide\u2010induced hematotoxicity, oxidative stress, and DNA damage in liver, kidney, and brain of catfish (Clarias gariepinus)","volume":"35","author":"Ibrahim","year":"2020","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.fsi.2024.109411_bib9","first-page":"3","article-title":"Acrylamide in environmental water: a review on sources, exposure, and public health risks, Expo","volume":"11","author":"Tepe","year":"2019","journal-title":"Health"},{"key":"10.1016\/j.fsi.2024.109411_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2022.109396","article-title":"Borax relieved the acrylamide-induced hematotoxic, hepatotoxic, immunotoxic and genotoxic damages in rainbow trout by regulating apoptosis and Nrf2 signaling pathway","volume":"259","author":"Atamanalp","year":"2022","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.fsi.2024.109411_bib11","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1002\/jat.2936","article-title":"Histopathological findings on Carassius auratus hepatopancreas upon exposure to acrylamide: correlation with genotoxicity and metabolic alterations","volume":"34","author":"Larguinho","year":"2014","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.fsi.2024.109411_bib12","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.envpol.2017.11.095","article-title":"Exposure to acrylamide induces cardiac developmental toxicity in zebrafish during cardiogenesis","volume":"234","author":"Huang","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.fsi.2024.109411_bib13","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.exer.2018.06.018","article-title":"Carnosic acid attenuates acrylamide-induced retinal toxicity in zebrafish embryos","volume":"175","author":"Albalawi","year":"2018","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.fsi.2024.109411_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109977","article-title":"Intake of acrylamide at the dietary relevant concentration causes splenic toxicity in adult zebrafish","volume":"189","author":"Komoike","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.fsi.2024.109411_bib15","article-title":"Potential role of dietary Boswellia serrata resin against mancozeb fungicide-induced immune-antioxidant suppression, histopathological alterations, and genotoxicity in Nile tilapia, Oreochromis niloticus","volume":"265","author":"Abdel Rahman","year":"2023","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.fsi.2024.109411_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2020.736247","article-title":"The stress of abamectin toxicity reduced water quality, growth performance, immunity and antioxidant capacity of Oreochromis niloticus fish: modulatory role of Simmondsia chinensis extract as a dietary supplement","volume":"534","author":"Mahmoud","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109411_bib17","first-page":"81","article-title":"The importance of microalgae for aquaculture industry. Review","volume":"2","author":"Sirakov","year":"2015","journal-title":"Int. J. Fish Aquat. Stud."},{"key":"10.1016\/j.fsi.2024.109411_bib18","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.fsi.2018.04.011","article-title":"Influences of Chlorella vulgaris dietary supplementation on growth performance, hematology, immune response and disease resistance in Oreochromis niloticus exposed to sub-lethal concentrations of penoxsulam herbicide","volume":"77","author":"Galal","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109411_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.738138","article-title":"Dietary supplementation of Chlorella vulgaris improved growth performance, immunity, intestinal microbiota and stress resistance of juvenile narrow clawed crayfish, Pontastacus leptodactylus Eschscholtz, 1823","volume":"554","author":"Safari","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109411_bib20","author":"Ibrahim","year":"2024"},{"key":"10.1016\/j.fsi.2024.109411_bib21","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.fsi.2022.08.062","article-title":"Addition of Chlorella sorokiniana meal in the diet of juvenile rainbow trout (Oncorhynchus mykiss): influence on fish growth, gut histology, oxidative stress, immune response, and disease resistance against Aeromonas salmonicida","volume":"129","author":"Chen","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109411_bib22","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.3390\/antiox12081565","article-title":"Dietary supplementation of Chlorella vulgaris effectively enhanced the intestinal antioxidant capacity and immune status of Micropterus salmoides","volume":"12","author":"Yu","year":"2023","journal-title":"Antioxidants"},{"issue":"5","key":"10.1016\/j.fsi.2024.109411_bib23","doi-asserted-by":"crossref","first-page":"675","DOI":"10.3390\/biology12050675","article-title":"Comparative evaluation of chlorella vulgaris and anabaena variabilis for phycoremediation of polluted river water: spotlighting heavy metals detoxification","volume":"12","author":"Ahammed","year":"2023","journal-title":"Biology"},{"key":"10.1016\/j.fsi.2024.109411_bib24","first-page":"308","article-title":"Ameliorative effects of selenium and Chlorella vulgaris against polystyrene nanoplastics-induced hepatotoxicity in african catfish (Clarias gariepinus)","volume":"12","author":"Abdelbaky","year":"2022","journal-title":"J. Adv. Vet. Res."},{"key":"10.1016\/j.fsi.2024.109411_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2023.106630","article-title":"Acute mancozeb-fungicide exposure induces neuro-ethology disruption, health disorders, and immune-oxidative dysfunction in Nile tilapia (Oreochromis niloticus)","volume":"261","author":"Ibrahim","year":"2023","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.fsi.2024.109411_bib26","first-page":"747","article-title":"Hepatoprotection of chlorella against carbon tetrachloride-induced oxidative damage in rats","volume":"23","author":"Peng","year":"2009","journal-title":"In Vivo"},{"key":"10.1016\/j.fsi.2024.109411_bib27","series-title":"Official Methods of Analysis of the AOAC International","author":"Aoac","year":"2000"},{"key":"10.1016\/j.fsi.2024.109411_bib28","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1577\/1548-8640(1971)33[132:AMFMDA]2.0.CO;2","article-title":"A method for measuring digestibility and metabolizable energy of fish feeds","volume":"33","author":"Smith","year":"1971","journal-title":"Progress. Fish Cult."},{"key":"10.1016\/j.fsi.2024.109411_bib29","series-title":"Nutrient Requirements of Fish and Shrimp","year":"2011"},{"key":"10.1016\/j.fsi.2024.109411_bib30","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.fsi.2014.09.035","article-title":"Modulatory role of dietary Chlorella vulgaris powder against arsenic-induced immunotoxicity and oxidative stress in Nile tilapia (Oreochromis niloticus)","volume":"41","author":"Zahran","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109411_bib31","series-title":"Standard Methods for Examination of Water and Wastewater","first-page":"9","year":"1998"},{"key":"10.1016\/j.fsi.2024.109411_bib32","series-title":"Probit Analysis","author":"Finney","year":"1971"},{"key":"10.1016\/j.fsi.2024.109411_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1163\/156853980X00140","article-title":"A causal analysis of the territorial and courtship behaviour of Chromis cyanea (Pomacentridae, Pisces)","volume":"73","author":"De Boer","year":"1980","journal-title":"Behaviour"},{"key":"10.1016\/j.fsi.2024.109411_bib34","series-title":"Fish Disease: Diagnosis and Treatment","author":"Noga","year":"2010"},{"issue":"3","key":"10.1016\/j.fsi.2024.109411_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1300\/J028v19n03_01","article-title":"Effect of buffered and unbuffered tricaine methanesulfonate (MS-222) at different concentrations on the stress responses of channel catfish, Ictalurus punctatus Rafinesque","volume":"19","author":"Welker","year":"2007","journal-title":"J. Appl. Aquacult."},{"key":"10.1016\/j.fsi.2024.109411_bib36","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/ajcp\/28.1.56","article-title":"A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases","volume":"28","author":"Reitman","year":"1957","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.fsi.2024.109411_bib37","series-title":"Tietz Textbook of Clinical Chemistry","author":"Burtis","year":"1994"},{"key":"10.1016\/j.fsi.2024.109411_bib38","first-page":"193","article-title":"Colorimetric kinetic method for creatinine determination in serum and urine","volume":"37","author":"Bartles","year":"1972","journal-title":"Clin. Chem. Acta."},{"key":"10.1016\/j.fsi.2024.109411_bib39","doi-asserted-by":"crossref","first-page":"55","DOI":"10.2989\/16085914.2017.1295918","article-title":"Cortisol stress response and histopathological alteration index in Clarias gariepinus exposed to sublethal concentrations of Qua Iboe crude oil and rig wash","volume":"42","author":"Saliu","year":"2017","journal-title":"Afr. J. Aquat. Sci."},{"key":"10.1016\/j.fsi.2024.109411_bib40","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0006-2952(61)90145-9","article-title":"RM feather stone, a new and rapid colorimetric determination of acetylcholinesterase activity","volume":"7","author":"Ellman","year":"1961","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.fsi.2024.109411_bib41","first-page":"101","article-title":"Lysozyme assays","volume":"1","author":"Ellis","year":"1990","journal-title":"Tech. Fish Immunol."},{"key":"10.1016\/j.fsi.2024.109411_bib42","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.fsi.2021.06.014","article-title":"Immune response and protective efficacy of two new adjuvants, Montanide\u2122 ISA 763B VG and Montanide\u2122 GEL02, administered with a Streptococcus agalactiae ghost vaccine in Nile tilapia (Oreochromis niloticus)","volume":"116","author":"Wangkaghart","year":"2021","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109411_bib43","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1097\/00007890-200209150-00007","article-title":"Targeting of glycosaminoglycan-cytokine interactions as a novel therapeutic approach in allotransplantation1","volume":"74","author":"Fernandez-Botran","year":"2002","journal-title":"Transplantation"},{"key":"10.1016\/j.fsi.2024.109411_bib44","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0003-2697(78)90342-1","article-title":"Determination of malonaldehyde precursor in tissues by thiobarbituric acid test","volume":"86","author":"Uchiyama","year":"1978","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.fsi.2024.109411_bib45","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S0006-291X(72)80218-3","article-title":"The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen","volume":"46","author":"Nishikimi","year":"1972","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.fsi.2024.109411_bib46","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","article-title":"[13] Catalase in vitro","author":"Aebi","year":"1984"},{"key":"10.1016\/j.fsi.2024.109411_bib47","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative CT method","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.fsi.2024.109411_bib48","series-title":"Bancroft's Theory and Practice of Histological Techniques","author":"Suvarna","year":"2018"},{"key":"10.1016\/j.fsi.2024.109411_bib49","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1177\/0300985813485099","article-title":"Principles for valid histopathologic scoring in research","volume":"50","author":"Gibson-Corley","year":"2013","journal-title":"Vet. Pathol."},{"key":"10.1016\/j.fsi.2024.109411_bib50","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1111\/jfd.12837","article-title":"Limited performance of MALDI\u2010TOF for identification of fish Aeromonas isolates at species level","volume":"41","author":"P\u00e9rez\u2010Sancho","year":"2018","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109411_bib51","doi-asserted-by":"crossref","first-page":"6423","DOI":"10.1007\/s11356-014-3177-0","article-title":"Dissemination of acrylamide monomer from polyacrylamide-based flocculant use\u2014sand and gravel quarry case study","volume":"22","author":"Touz\u00e9","year":"2015","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.fsi.2024.109411_bib52","first-page":"3","article-title":"Acrylamide in environmental water: a review on sources, exposure, and public health risks, Expo","volume":"11","author":"Tepe","year":"2019","journal-title":"Health"},{"key":"10.1016\/j.fsi.2024.109411_bib53","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/0043-1354(80)90254-7","article-title":"Model studies of the degradation of acrylamide monomer","volume":"14","author":"Brown","year":"1980","journal-title":"Water Res."},{"key":"10.1016\/j.fsi.2024.109411_bib54","series-title":"Acrylamide, in: Guidelines for Drinking Water Quality, Health Criteria and Other Supporting Information, International Programme on Chemical Safety","year":"1996"},{"key":"10.1016\/j.fsi.2024.109411_bib55","series-title":"Drinking Water Contaminants\u2014Standards and Regulations","author":"Agency","year":"2016"},{"key":"10.1016\/j.fsi.2024.109411_bib56","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/BF01141341","article-title":"Acute toxicity of endosulfan to the fish Hyphessobrycon bifasciatus and Brachydanio rerio","volume":"24","author":"Jonsson","year":"1993","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.fsi.2024.109411_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.anifeedsci.2021.115181","article-title":"Dietary Chlorella vulgaris modulates the performance, antioxidant capacity, innate immunity, and disease resistance capability of Nile tilapia fingerlings fed on plant-based diets","volume":"283","author":"Abdel-Tawwab","year":"2022","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.fsi.2024.109411_bib58","doi-asserted-by":"crossref","first-page":"793","DOI":"10.4194\/AQUAST793","article-title":"Influences of dietary supplementation of chlorella vulgaris and spirulina platensis on growth-related genes expression and antioxidant enzymes in oreochromis niloticus fish exposed to heavy metals","volume":"22","author":"Saleh","year":"2021","journal-title":"Aquac. Stud."},{"key":"10.1016\/j.fsi.2024.109411_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.736841","article-title":"Nutritional applications of species of Spirulina and Chlorella in farmed fish: a review","volume":"542","author":"Alagawany","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109411_bib60","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/raq.12320","article-title":"Applications of microalga Chlorella vulgaris in aquaculture","volume":"12","author":"Ahmad","year":"2020","journal-title":"Rev. Aquacult."},{"key":"10.1016\/j.fsi.2024.109411_bib61","first-page":"157","article-title":"Determination of mancozeb toxicity and biochemical effects in common carp (Cyprinus carpio)","volume":"6","author":"Simakani","year":"2018","journal-title":"Int. J. Aquat. Biol."},{"key":"10.1016\/j.fsi.2024.109411_bib62","doi-asserted-by":"crossref","unstructured":"S.C. Sikka, N. Gurbuz, Reproductive Toxicity of Organophosphate and Carbamate Pesticides, Toxicology of organophosphate & carbamate compounds, Elsevier2006, pp. 447-462.","DOI":"10.1016\/B978-012088523-7\/50033-8"},{"key":"10.1016\/j.fsi.2024.109411_bib63","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3390\/antiox8070199","article-title":"Promises and challenges of microalgal antioxidant production","volume":"8","author":"Sansone","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.fsi.2024.109411_bib64","article-title":"The effect of dietary Crataegus Sinaica on the growth performance, immune responses, hemato-biochemical and oxidative stress indices, tissues architecture, and resistance to Aeromonas sobria infection of acrylamide-exposed Clarias gariepinus","volume":"30","author":"El-Houseiny","year":"2023","journal-title":"Aquac. Rep."},{"key":"10.1016\/j.fsi.2024.109411_bib65","first-page":"299","article-title":"Development, Protective effects of selenium and alpha-tocopherol against lead-induced hepatic and renal toxicity in Oreochromis niloticus","volume":"6","author":"Elgaml","year":"2015","journal-title":"J. Aquacult. Res. Dev."},{"key":"10.1016\/j.fsi.2024.109411_bib66","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1248\/bpb.b12-00187","article-title":"Anti-inflammatory effects of violaxanthin isolated from microalga Chlorella ellipsoidea in RAW 264.7 macrophages","volume":"35","author":"Soontornchaiboon","year":"2012","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.fsi.2024.109411_bib67","first-page":"897","article-title":"Protective effect of Spirulina and tamarind fruit pulp diet supplement in fish (Gambusia affinis Baird & Girard) exposed to sublethal concentration of fluoride, aluminum and aluminum fluoride","volume":"50","author":"Sharma","year":"2012","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.fsi.2024.109411_bib68","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.fsi.2014.09.035","article-title":"Modulatory role of dietary Chlorella vulgaris powder against arsenic-induced immunotoxicity and oxidative stress in Nile tilapia (Oreochromis niloticus)","volume":"41","author":"Zahran","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109411_bib69","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s12562-018-1274-6","article-title":"Dietary supplementation of Chlorella vulgaris ameliorates chronic sodium arsenite toxicity in Nile tilapia Oreochromis niloticus as revealed by histopathological, biochemical and immune gene expression analysis","volume":"85","author":"Zahran","year":"2019","journal-title":"Fish. Sci."},{"key":"10.1016\/j.fsi.2024.109411_bib70","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/j.bbrc.2018.04.206","article-title":"Red alga polysaccharides attenuate angiotensin II-induced inflammation in coronary endothelial cells","volume":"500","author":"Hamias","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.fsi.2024.109411_bib71","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jhazmat.2018.01.016","article-title":"Characterization of acrylamide-induced oxidative stress and cardiovascular toxicity in zebrafish embryos","volume":"347","author":"Huang","year":"2018","journal-title":"J. Hazard Mater. Lett."},{"key":"10.1016\/j.fsi.2024.109411_bib72","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1111\/1750-3841.15313","article-title":"Protective effect of seabuckthorn berry juice against acrylamide\u2010induced oxidative damage in rats","volume":"85","author":"Zhao","year":"2020","journal-title":"J. Food Sci."},{"key":"10.1016\/j.fsi.2024.109411_bib73","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1016\/j.intimp.2006.04.013","article-title":"Macrophage activation by polysaccharide biological response modifier isolated from Aloe vera L. var. chinensis (Haw.) Berg","volume":"6","author":"Liu","year":"2006","journal-title":"Int. Immunopharm."},{"key":"10.1016\/j.fsi.2024.109411_bib74","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.3390\/life13041028","article-title":"Protective effects of Chlorella vulgaris supplemented diet on antibacterial activity and immune responses in rohu fingerlings, Labeo rohita (Hamilton), subjected to Aeromonas hydrophila infection","volume":"13","author":"Pradhan","year":"2023","journal-title":"Life"},{"key":"10.1016\/j.fsi.2024.109411_bib75","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/raq.12320","article-title":"Applications of microalga Chlorella vulgaris in aquaculture","volume":"12","author":"Ahmad","year":"2020","journal-title":"Rev. Aquacult."}],"updated-by":[{"DOI":"10.1016\/j.fsi.2024.109462","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000}}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105046482400055X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105046482400055X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T05:52:00Z","timestamp":1760939520000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S105046482400055X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":75,"alternative-id":["S105046482400055X"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2024.109411","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.fsi.2024.109462","asserted-by":"object"}]},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acrylamide exposure induces growth retardation, neurotoxicity, stress, and immune\/antioxidant disruption in Nile tilapia (Oreochromis niloticus): The alleviative effects of Chlorella vulgaris diets","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2024.109411","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109411"}}