{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T18:58:52Z","timestamp":1788807532657,"version":"build-2803163510"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010801","name":"Xunta de Galicia","doi-asserted-by":"publisher","award":["IN607B 2022\/13"],"award-info":[{"award-number":["IN607B 2022\/13"]}],"id":[{"id":"10.13039\/501100010801","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010556","name":"Xunta de Galicia Conselleria de Economia e Industria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010556","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Gobierno de Espa\u00f1a Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["PID2021-124955OB-I00"],"award-info":[{"award-number":["PID2021-124955OB-I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.fsi.2024.109867","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T02:11:14Z","timestamp":1724897474000},"page":"109867","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Transcriptomic and functional analysis of the antiviral response of mussels after a poly I:C stimulation"],"prefix":"10.1016","volume":"153","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3711-8187","authenticated-orcid":false,"given":"Magal\u00ed","family":"Rey-Campos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7310-9267","authenticated-orcid":false,"given":"Amaro","family":"Saco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4888-8419","authenticated-orcid":false,"given":"Beatriz","family":"Novoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Figueras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2024.109867_bib1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/sj.cr.7310019","article-title":"Antiviral innate immunity pathways","volume":"16","author":"Seth","year":"2006","journal-title":"Cell Res."},{"key":"10.1016\/j.fsi.2024.109867_bib2","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/s41559-022-01951-4","article-title":"Origins and diversification of animal innate immune responses against viral infections","volume":"7","author":"Iwama","year":"2023","journal-title":"Nat. Ecol. Evol."},{"key":"10.1016\/j.fsi.2024.109867_bib3","series-title":"The State of World Fisheries and Aquaculture 2022. Towards Blue Transformation","year":"2022"},{"key":"10.1016\/j.fsi.2024.109867_bib4","doi-asserted-by":"crossref","first-page":"5419","DOI":"10.1128\/AEM.00484-14","article-title":"Ostreid herpesvirus 1 infection among Pacific oyster (Crassostrea gigas) Spat: relevance of water temperature to virus replication and circulation prior to the onset of mortality","volume":"80","author":"Renault","year":"2014","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.fsi.2024.109867_bib5","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.jip.2014.11.007","article-title":"Emerging and endemic types of Ostreid herpesvirus 1 were detected in bivalves in China","volume":"124","author":"Bai","year":"2015","journal-title":"J. Invertebr. Pathol."},{"key":"10.1016\/j.fsi.2024.109867_bib6","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1006\/viro.2001.1186","article-title":"French scallops: a new host for ostreid herpesvirus-1","volume":"290","author":"Arzul","year":"2001","journal-title":"Virology"},{"key":"10.1016\/j.fsi.2024.109867_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/v13112315","article-title":"Susceptibility of Four Abalone Species, Haliotis gigantea, Haliotis discus discus, Haliotis discus hannai and Haliotis diversicolor, to Abalone asfa-like Virus","volume":"13","author":"Matsuyama","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.fsi.2024.109867_bib8","article-title":"Abalone viral ganglioneuritis","volume":"9","author":"Corbeil","year":"2020","journal-title":"Pathog. Basel Switz."},{"key":"10.1016\/j.fsi.2024.109867_bib9","doi-asserted-by":"crossref","first-page":"239","DOI":"10.3354\/dao03180","article-title":"Evaluation of blue mussel Mytilus edulis as vector for viral hemorrhagic septicemia virus (VHSV)","volume":"126","author":"Kim","year":"2017","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2024.109867_bib10","doi-asserted-by":"crossref","first-page":"7692","DOI":"10.1128\/JVI.00591-16","article-title":"Antiviral activity of myticin C peptide from mussel: an ancient defense against herpesviruses","volume":"90","author":"Novoa","year":"2016","journal-title":"J. Virol."},{"key":"10.1016\/j.fsi.2024.109867_bib11","article-title":"Mediterranean aquaculture in a changing climate: temperature effects on pathogens and diseases of three farmed fish species","volume":"10","author":"Cascarano","year":"2021","journal-title":"Pathog. Basel Switz."},{"key":"10.1016\/j.fsi.2024.109867_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2023.1209103","article-title":"Metatranscriptomics unmasks Mollusca virome with a remarkable presence of rhabdovirus in cephalopods","volume":"10","author":"Rey-Campos","year":"2023","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.fsi.2024.109867_bib13","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/nature19366","article-title":"Tara Oceans Coordinators, Ecogenomics and potential biogeochemical impacts of globally abundant ocean viruses","volume":"537","author":"Roux","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.fsi.2024.109867_bib14","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1126\/science.abn6358","article-title":"Diversity and ecological footprint of Global Ocean RNA viruses","volume":"376","author":"Dominguez-Huerta","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.fsi.2024.109867_bib15","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.jip.2017.01.009","article-title":"Viruses infecting marine molluscs","volume":"147","author":"Arzul","year":"2017","journal-title":"J. Invertebr. Pathol."},{"key":"10.1016\/j.fsi.2024.109867_bib16","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/nrmicro1750","article-title":"Marine viruses-major players in the global ecosystem","volume":"5","author":"Suttle","year":"2007","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.fsi.2024.109867_bib17","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3354\/dao02701","article-title":"Occurrence, seasonality and infectivity of Vibrio strains in natural populations of mussels Mytilus galloprovincialis","volume":"108","author":"Romero","year":"2014","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2024.109867_bib18","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1186\/s13059-020-02180-3","article-title":"Massive gene presence-absence variation shapes an open pan-genome in the Mediterranean mussel","volume":"21","author":"Gerdol","year":"2020","journal-title":"Genome Biol."},{"key":"10.1016\/j.fsi.2024.109867_bib19","doi-asserted-by":"crossref","DOI":"10.1093\/molbev\/msad133","article-title":"Bivalves present the largest and most diversified repertoire of toll-like receptors in the animal kingdom, suggesting broad-spectrum pathogen recognition in marine waters","volume":"40","author":"Saco","year":"2023","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.fsi.2024.109867_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/biom10060943","article-title":"Comparative genomics reveals a significant sequence variability of myticin genes in Mytilus galloprovincialis","volume":"10","author":"Rey-Campos","year":"2020","journal-title":"Biomolecules"},{"key":"10.1016\/j.fsi.2024.109867_bib21","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22063235","article-title":"Comparative genomics reveals 13 different isoforms of mytimycins (A-M) in Mytilus galloprovincialis","volume":"22","author":"Rey-Campos","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.fsi.2024.109867_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.692997","article-title":"The evolution and diversity of interleukin-17 highlight an expansion in marine invertebrates and its conserved role in mucosal immunity","volume":"12","author":"Saco","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib23","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00407-20","article-title":"Towards a mechanism for poly(I\u00b7C) antiviral priming in oysters","volume":"11","author":"Martins","year":"2020","journal-title":"mBio"},{"key":"10.1016\/j.fsi.2024.109867_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2023.104668","article-title":"A conserved RNAi molecule Ago2 involved in antiviral immunity of oyster Crassostrea gigas","volume":"142","author":"Jin","year":"2023","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib25","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.fsi.2019.10.067","article-title":"The Dicer from oyster Crassostrea gigas functions as an intracellular recognition molecule and effector in anti-viral immunity","volume":"95","author":"Lv","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108735","article-title":"Mussel antiviral transcriptome response and elimination of viral haemorrhagic septicaemia virus (VHSV)","volume":"136","author":"Saco","year":"2023","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib27","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.fsi.2013.04.051","article-title":"Poly I:C induces a protective antiviral immune response in the Pacific oyster (Crassostrea gigas) against subsequent challenge with Ostreid herpesvirus (OsHV-1 \u03bcvar)","volume":"35","author":"Green","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib28","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.fsi.2007.11.008","article-title":"Poly I:C induces Mx transcription and promotes an antiviral state against sole aquabirnavirus in the flatfish Senegalese sole (Solea senegalensis Kaup)","volume":"24","author":"Fernandez-Trujillo","year":"2008","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108544","article-title":"Sequencing-based network analysis provides a core set of genes for understanding hemolymph immune response mechanisms against Poly I:C stimulation in Amphioctopus fangsiao","volume":"133","author":"Chen","year":"2023","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpb.2021.110608","article-title":"Characterization of a novel toll-like receptor and activation NF-\u03baB signal pathway in triangle sail mussel Hyriopsis cumingii","volume":"255","author":"Yin","year":"2021","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.fsi.2024.109867_bib31","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.fsi.2022.08.005","article-title":"The first identified invertebrate LGP2-like homolog gene in the Pacific oyster Crassostrea gigas","volume":"128","author":"Huang","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib32","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.fsi.2022.04.042","article-title":"Scallop RIG-I-like receptor 1 responses to polyinosinic:polycytidylic acid challenge and its interactions with the mitochondrial antiviral signaling protein","volume":"124","author":"Sang","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib33","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.fsi.2018.09.027","article-title":"Identification and functional characterization of three myeloid differentiation factor 88 (MyD88) isoforms from thick shell mussel Mytilus coruscus","volume":"83","author":"Guo","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib34","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.fsi.2017.06.049","article-title":"Molecular cloning and functional analysis of tumor necrosis factor receptor-associated factor 6 (TRAF6) in Crossastrea gigas","volume":"68","author":"Mao","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib35","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.dci.2011.03.023","article-title":"Involvement of pore-forming molecules in immune defense and development of the Mediterranean mussel (Mytilus galloprovincialis)","volume":"35","author":"Est\u00e9vez-Calvar","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2021.104286","article-title":"Genomic and transcriptomic identification of the cathepsin superfamily in the Mediterranean mussel Mytilus galloprovincialis","volume":"127","author":"Romero","year":"2022","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib37","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.fsi.2006.09.007","article-title":"First report of invertebrate Mx: cloning, characterization and expression analysis of Mx cDNA in disk abalone (Haliotis discus discus)","volume":"23","author":"De Zoysa","year":"2007","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib38","doi-asserted-by":"crossref","first-page":"3587","DOI":"10.1099\/jgv.0.000300","article-title":"Oyster viperin retains direct antiviral activity and its transcription occurs via a signalling pathway involving a heat-stable haemolymph protein","volume":"96","author":"Green","year":"2015","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.fsi.2024.109867_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2021.104206","article-title":"A novel CgIFNLP receptor involved in regulating ISG expression in oyster Crassostrea gigas","volume":"124","author":"Qiao","year":"2021","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib40","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3354\/dao02615","article-title":"Spatial distribution of mortality in Pacific oysters Crassostrea gigas: reflection on mechanisms of OsHV-1 transmission","volume":"105","author":"Paul-Pont","year":"2013","journal-title":"Dis. Aquat. Org."},{"issue":"423","key":"10.1016\/j.fsi.2024.109867_bib41","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.aquaculture.2013.12.009","article-title":"Descriptive epidemiology of mass mortality due to Ostreid herpesvirus-1 (OsHV-1) in commercially farmed Pacific oysters (Crassostrea gigas) in the Hawkesbury River estuary, Australia","volume":"422","author":"Paul-Pont","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109867_bib42","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.prevetmed.2012.02.001","article-title":"Investigation of mortality in Pacific oysters associated with Ostreid herpesvirus-1\u03bcVar in the Republic of Ireland in 2009","volume":"105","author":"Peeler","year":"2012","journal-title":"Prev. Vet. Med."},{"key":"10.1016\/j.fsi.2024.109867_bib43","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.virusres.2010.07.011","article-title":"Detection and description of a particular Ostreid herpesvirus 1 genotype associated with massive mortality outbreaks of Pacific oysters, Crassostrea gigas, in France in 2008","volume":"153","author":"Segarra","year":"2010","journal-title":"Virus Res."},{"key":"10.1016\/j.fsi.2024.109867_bib44","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.fsi.2013.10.026","article-title":"Ontogeny and water temperature influences the antiviral response of the Pacific oyster, Crassostrea gigas","volume":"36","author":"Green","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib45","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.fsi.2015.05.023","article-title":"Transcriptome analysis reveals strong and complex antiviral response in a mollusc","volume":"46","author":"He","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib46","doi-asserted-by":"crossref","DOI":"10.3390\/v10030133","article-title":"Antiviral defense and innate immune memory in the oyster","volume":"10","author":"Green","year":"2018","journal-title":"Viruses"},{"key":"10.1016\/j.fsi.2024.109867_bib47","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-13564-0","article-title":"Long-lasting antiviral innate immune priming in the Lophotrochozoan Pacific oyster, Crassostrea gigas","volume":"7","author":"Lafont","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fsi.2024.109867_bib48","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02777-19","article-title":"A sustained immune response supports long-term antiviral immune priming in the pacific oyster, Crassostrea gigas","volume":"11","author":"Lafont","year":"2020","journal-title":"mBio"},{"key":"10.1016\/j.fsi.2024.109867_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.689783","article-title":"The cGAS\/STING\u2013TBK1\u2013IRF regulatory Axis orchestrates a primitive interferon-like antiviral mechanism in oyster","volume":"12","author":"Qiao","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib50","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.molimm.2016.09.002","article-title":"Primed for success: oyster parents treated with poly(I:C) produce offspring with enhanced protection against Ostreid herpesvirus type I infection","volume":"78","author":"Green","year":"2016","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib51","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.fsi.2020.04.047","article-title":"Fitness costs associated with maternal immune priming in the oyster","volume":"103","author":"Robinson","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib52","doi-asserted-by":"crossref","first-page":"e323","DOI":"10.1002\/cpz1.323","article-title":"BUSCO: assessing genomic data quality and beyond","volume":"1","author":"Manni","year":"2021","journal-title":"Curr. Protoc."},{"key":"10.1016\/j.fsi.2024.109867_bib53","doi-asserted-by":"crossref","first-page":"3420","DOI":"10.1093\/nar\/gkn176","article-title":"High-throughput functional annotation and data mining with the Blast2GO suite","volume":"36","author":"G\u00f6tz","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.fsi.2024.109867_bib54","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.fsi.2024.109867_bib55","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc. Ser. B Methodol."},{"key":"10.1016\/j.fsi.2024.109867_bib56","doi-asserted-by":"crossref","first-page":"e74","DOI":"10.1093\/nar\/gkt006","article-title":"CPAT: coding-Potential Assessment Tool using an alignment-free logistic regression model","volume":"41","author":"Wang","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.fsi.2024.109867_bib57","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/biomet\/30.1-2.81","article-title":"A new measure of rank correlation","volume":"30","author":"Kendall","year":"1938","journal-title":"Biometrika"},{"key":"10.1016\/j.fsi.2024.109867_bib58","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1007\/s12560-019-09392-2","article-title":"Interlaboratory comparative study to detect potentially infectious human enteric viruses in influent and effluent waters","volume":"11","author":"Randazzo","year":"2019","journal-title":"Food Environ. Virol."},{"key":"10.1016\/j.fsi.2024.109867_bib59","doi-asserted-by":"crossref","first-page":"e115","DOI":"10.1093\/nar\/gks596","article-title":"Primer3-new capabilities and interfaces","volume":"40","author":"Untergasser","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.fsi.2024.109867_bib60","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.fsi.2024.109867_bib61","doi-asserted-by":"crossref","DOI":"10.3390\/md21040254","article-title":"A genomic and transcriptomic analysis of the C-type lectin gene family reveals highly expanded and diversified repertoires in bivalves","volume":"21","author":"Saco","year":"2023","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.fsi.2024.109867_bib62","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.fsi.2011.10.017","article-title":"Gene expression specificity of the mussel antifungal mytimycin (MytM)","volume":"32","author":"Sonthi","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib63","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.615580","article-title":"Transcriptomic response of mussel gills after a Vibrio splendidus infection demonstrates their role in the immune response","volume":"11","author":"Saco","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib64","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.3389\/fimmu.2019.01894","article-title":"Immune tolerance in Mytilus galloprovincialis hemocytes after repeated contact with Vibrio splendidus","volume":"10","author":"Rey-Campos","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib65","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1186\/s12864-020-06914-2","article-title":"New insights into the Manila clam and PAMPs interaction based on RNA-seq analysis of clam through in vitro challenges with LPS, PGN, and poly(I:C)","volume":"21","author":"Jiang","year":"2020","journal-title":"BMC Genom."},{"key":"10.1016\/j.fsi.2024.109867_bib66","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.fsi.2009.08.001","article-title":"Immune response and gene expression in shrimp (Litopenaeus vannamei) hemocytes and hepatopancreas against some pathogen-associated molecular patterns","volume":"27","author":"Ji","year":"2009","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib67","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.fsi.2018.07.032","article-title":"Differential lncRNA expression profiles reveal the potential roles of lncRNAs in antiviral immune response of Crassostrea gigas","volume":"81","author":"Sun","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib68","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.fsi.2019.12.015","article-title":"LncMSEN1, a mantle-specific LncRNA participating in nacre formation and response to polyI:C stimulation in pearl oyster Pinctada fucata martensii","volume":"96","author":"Zheng","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109867_bib69","doi-asserted-by":"crossref","DOI":"10.3390\/genes12091393","article-title":"Differential expression of long non-coding RNA (lncRNA) in mediterranean mussel (Mytilus galloprovincialis) hemocytes under immune stimuli","volume":"12","author":"Pereiro","year":"2021","journal-title":"Genes"},{"key":"10.1016\/j.fsi.2024.109867_bib70","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s12560-016-9234-8","article-title":"Temperature-dependent persistence of human norovirus within oysters (Crassostrea virginica)","volume":"8","author":"Choi","year":"2016","journal-title":"Food Environ. Virol."},{"key":"10.1016\/j.fsi.2024.109867_bib71","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1038\/s41598-019-39870-3","article-title":"High individual variability in the transcriptomic response of Mediterranean mussels to Vibrio reveals the involvement of myticins in tissue injury","volume":"9","author":"Rey-Campos","year":"2019","journal-title":"Sci. Rep."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464824005126?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464824005126?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T04:39:29Z","timestamp":1726115969000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464824005126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":71,"alternative-id":["S1050464824005126"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2024.109867","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptomic and functional analysis of the antiviral response of mussels after a poly I:C stimulation","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2024.109867","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"109867"}}