{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:02:00Z","timestamp":1791594120449,"version":"4.3.4"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T00:00:00Z","timestamp":1762041600000},"content-version":"am","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP20J22961"],"award-info":[{"award-number":["JP20J22961"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP22KJ1390"],"award-info":[{"award-number":["JP22KJ1390"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009029","name":"Adaptable and Seamless Technology Transfer Program through Target-Driven R and D","doi-asserted-by":"publisher","award":["JPMJTR20U5"],"award-info":[{"award-number":["JPMJTR20U5"]}],"id":[{"id":"10.13039\/501100009029","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.fsi.2024.109991","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T07:22:02Z","timestamp":1730272922000},"page":"109991","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Cell-mediated and humoral immune responses of cyprinids induced by a live attenuated vaccine against cyprinid herpesvirus 2 infection in comparison to the virus non-permissive high temperature water treatment"],"prefix":"10.1016","volume":"154","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3165-0340","authenticated-orcid":false,"given":"Hiroaki","family":"Saito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9012-3949","authenticated-orcid":false,"given":"Lik-Ming","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shungo","family":"Minami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manami","family":"Yuguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1576-5654","authenticated-orcid":false,"given":"Teruyuki","family":"Nakanishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5102-6831","authenticated-orcid":false,"given":"Hidehiro","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goshi","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7148-1329","authenticated-orcid":false,"given":"Motohiko","family":"Sano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2024.109991_bib1","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1365-2761.1995.tb00296.x","article-title":"Herpesviral haematopoietic necrosis of goldfish, Carassius auratus (L.)","volume":"18","author":"Jung","year":"1995","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib2","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/j.1365-2761.2007.00847.x","article-title":"Isolation of a cyprinid herpesvirus 2 from goldfish, Carassius auratus (L.), in the UK","volume":"30","author":"Jeffery","year":"2007","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib3","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/jfd.12400","article-title":"First detection of cyprinid herpesvirus 2 (CyHV\u20102) in goldfish (Carassius auratus) in France","volume":"39","author":"Boitard","year":"2016","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib4","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/jfd.12734","article-title":"CyHV\u20102 transmission in traded goldfish stocks in Germany\u2014a case study","volume":"41","author":"Adamek","year":"2018","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib5","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.aquaculture.2019.01.065","article-title":"Detection of cyprinid herpesvirus 2 (CyHV-2) in symptomatic ornamental types of goldfish (Carassius auratus) and asymptomatic common carp (Cyprinus carpio) reared in warm-water cage culture","volume":"504","author":"Panicz","year":"2019","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109991_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.738854","article-title":"Investigation of the latency of Cyprinid herpesvirus 2 in apparently healthy farmed gibel carp, Carassius auratus gibelio","volume":"562","author":"Wei","year":"2023","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109991_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2023.740481","article-title":"First report of natural Cyprinid herpesvirus-2 infection associated with fatal outbreaks of goldfish (Carassius auratus) farms in Thailand","volume":"581","author":"Piewbang","year":"2024","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109991_bib8","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/jfd.12048","article-title":"Detection of Cyprinid herpesvirus 2 in association with an Aeromonas sobria infection of Carassius (L.), in Italy","volume":"36","author":"Fichi","year":"2013","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib9","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.vetmic.2013.05.025","article-title":"Cyprinid herpesvirus 2 infection emerged in cultured gibel carp, Carassius auratus gibelio in China","volume":"166","author":"Xu","year":"2013","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.fsi.2024.109991_bib10","first-page":"37","article-title":"Elevating water temperature for control of herpesviral hematopoietic necrosis of goldfish, Carassius auratus","volume":"5","author":"Tanaka","year":"2005","journal-title":"Bull. Saitama Pref. Agriculture, Forestry and Fisheries Research Center"},{"key":"10.1016\/j.fsi.2024.109991_bib11","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3354\/dao02759","article-title":"Effects of experimentally induced infections of goldfish Carassius auratus with cyprinid herpesvirus 2 (CyHV-2) at various water temperatures","volume":"110","author":"Ito","year":"2014","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2024.109991_bib12","first-page":"62","article-title":"Passive immunization of goldfish with the serum of those surviving a cyprinid herpesvirus 2 infection after high temperature water treatment","volume":"37","author":"Nanjo","year":"2017","journal-title":"Bull. Eur. Assoc. Fish Pathol."},{"key":"10.1016\/j.fsi.2024.109991_bib13","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1111\/jfd.12996","article-title":"Persistence of cyprinid herpesvirus 2 in asymptomatic goldfish Carassius auratus (L.) that survived an experimental infection","volume":"42","author":"Wei","year":"2019","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib14","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.fsi.2020.05.020","article-title":"Reactivation of cyprinid herpesvirus 2 (CyHV-2) in asymptomatic surviving goldfish Carassius auratus (L.) under immunosuppression","volume":"103","author":"Wei","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.737974","article-title":"Development of a live attenuated vaccine candidate against herpesviral hematopoietic necrosis of goldfish","volume":"552","author":"Saito","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109991_bib16","doi-asserted-by":"crossref","first-page":"569","DOI":"10.3390\/microorganisms7110569","article-title":"A review of fish vaccine development strategies: conventional methods and modern biotechnological approaches","volume":"7","author":"Ma","year":"2019","journal-title":"Microorganisms"},{"key":"10.1016\/j.fsi.2024.109991_bib17","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/ni.3123","article-title":"Control of adaptive immunity by the innate immune system","volume":"16","author":"Iwasaki","year":"2015","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib18","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.jaci.2009.12.980","article-title":"Overview of the immune response","volume":"125","author":"Chaplin","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib19","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.cell.2010.02.021","article-title":"Th17 and regulatory T cells in mediating and restraining inflammation","volume":"140","author":"Litman","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.fsi.2024.109991_bib20","doi-asserted-by":"crossref","first-page":"640","DOI":"10.3390\/biology4040640","article-title":"T cells in fish","volume":"4","author":"Nakanishi","year":"2015","journal-title":"Biology"},{"key":"10.1016\/j.fsi.2024.109991_bib21","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1111\/jfd.13476","article-title":"Kinetics of CD4\u20101+ lymphocytes in brown trout after exposure to viral haemorrhagic septicaemia virus","volume":"44","author":"Ashfaq","year":"2021","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib22","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/jfd.12500","article-title":"Susceptibility of isogeneic ginbuna Carassius auratus langsdorfii Temminck et Schlegel to cyprinid herpesvirus\u20102 (CyHV\u20102) as a model species","volume":"40","author":"Nanjo","year":"2017","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib23","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.dci.2013.12.008","article-title":"Helper function of CD4+ lymphocytes in antiviral immunity in ginbuna crucian carp, Carassius auratus langsdorfii","volume":"44","author":"Somamoto","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib24","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.dci.2012.11.001","article-title":"Identification of anti-viral cytotoxic effector cells in the ginbuna crucian carp, Carassius auratus langsdorfii","volume":"39","author":"Somamoto","year":"2013","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib25","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.dci.2018.12.009","article-title":"Generation of virus-specific CD8+ T cells by vaccination with inactivated virus in the intestine of ginbuna crucian carp","volume":"93","author":"Tajimi","year":"2019","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.dci.2016.12.002","article-title":"Cross-reactivity of monoclonal antibodies against CD4-1 and CD8\u03b1 of ginbuna crucian carp with lymphocytes of zebrafish and other cyprinid species","volume":"80","author":"Miyazawa","year":"2018","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib27","doi-asserted-by":"crossref","first-page":"223","DOI":"10.3354\/dao02885","article-title":"In vitro characteristics of cyprinid herpesvirus 2: effect of kidney extract supplementation on growth","volume":"115","author":"Shibata","year":"2015","journal-title":"Dis. Aquat. Organ."},{"key":"10.1016\/j.fsi.2024.109991_bib28","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.dci.2010.05.009","article-title":"Kinetics of CD4+ and CD8\u03b1+ T-cell subsets in graft-versus-host reaction (GVHR) in ginbuna crucian carp Carassius auratus langsdorfii","volume":"34","author":"Shibasaki","year":"2010","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib29","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.dci.2011.01.013","article-title":"Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish","volume":"35","author":"Toda","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2023.740140","article-title":"Efficient showering vaccination with a live attenuated vaccine against herpesviral hematopoietic necrosis in goldfish","volume":"578","author":"Saito","year":"2024","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2024.109991_bib31","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3354\/dao069137","article-title":"Detection of the herpesviral hematopoietic necrosis disease agent (Cyprinid herpesvirus 2) in moribund and healthy goldfish: validation of a quantitative PCR diagnostic method","volume":"69","author":"Goodwin","year":"2006","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2024.109991_bib32","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/10618600.1996.10474713","article-title":"R: a language for data analysis and graphics","volume":"5","author":"Ihaka","year":"1996","journal-title":"J. Comput. Graph Stat."},{"key":"10.1016\/j.fsi.2024.109991_bib33","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.fsi.2019.08.036","article-title":"Immersion immunization with recombinant baculoviruses displaying cyprinid herpesvirus 2 membrane proteins induced protective immunity in gibel carp","volume":"93","author":"Cao","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib34","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.fsi.2022.03.027","article-title":"Immunological insights into the resistance of Nile tilapia strains to an infection with tilapia lake virus","volume":"124","author":"Adamek","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib35","doi-asserted-by":"crossref","DOI":"10.1111\/jfd.13906","article-title":"Effect of temperature on the protective efficacy of a live attenuated vaccine against herpesviral haematopoietic necrosis in goldfish","author":"Saito","year":"2024","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2024.109991_bib36","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.fsi.2016.01.003","article-title":"Immune response and protection in gibel carp, Carassius gibelio, after vaccination with \u03b2-propiolactone inactivated cyprinid herpesvirus 2","volume":"49","author":"Zhang","year":"2016","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib37","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3390\/microorganisms8030445","article-title":"Evaluation of cyprinid herpesvirus 2 latency and reactivation in carassius gibel","volume":"8","author":"Chai","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.fsi.2024.109991_bib38","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.fsi.2018.12.027","article-title":"Aquatic animal viruses mediated immune evasion in their host","volume":"86","author":"Ke","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib39","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.3389\/fmicb.2019.02923","article-title":"Cyprinid herpesvirus 2 miR-C12 attenuates virus-mediated apoptosis and promotes virus propagation by targeting caspase 8","volume":"10","author":"Lu","year":"2019","journal-title":"Front. Microbiol."},{"issue":"5","key":"10.1016\/j.fsi.2024.109991_bib40","first-page":"158","article-title":"Vaccination against cyprinid herpesvirus 2 (CyHV-2) infection in goldfish Carassius auratus","volume":"33","author":"Ito","year":"2013","journal-title":"Bull. Eur. Assoc. Fish Pathol."},{"issue":"1","key":"10.1016\/j.fsi.2024.109991_bib41","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.vetmic.2014.11.005","article-title":"Effect of booster shot and investigation of vaccination efficacy period against herpesviral haematopoietic necrosis (HVHN) in goldfish Carassius auratus","volume":"175","author":"Ito","year":"2015","journal-title":"Vet. Microbiol."},{"issue":"2","key":"10.1016\/j.fsi.2024.109991_bib42","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.fsi.2010.03.005","article-title":"Immunocytochemical studies of the ontogeny of peripheral blood leucocyte subpopulations in Japanese flounder (Paralichthys olivaceus)","volume":"29","author":"Matsuyama","year":"2010","journal-title":"Fish Shellfish Immunol."},{"issue":"3\u20134","key":"10.1016\/j.fsi.2024.109991_bib43","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.dci.2012.02.014","article-title":"Ontogeny of anti-viral hemorrhagic septicemia virus (VHSV) immunity in developing Japanese flounder","volume":"37","author":"Matsuyama","year":"2012","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib44","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.dci.2008.11.008","article-title":"Alloantigen-specific killing is mediated by CD8-positive T cells in fish","volume":"33","author":"Toda","year":"2009","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.virol.2019.11.014","article-title":"Cloning and characterization of antiviral cytotoxic T lymphocytes in channel catfish, Ictalurus punctatus","volume":"540","author":"Taylor","year":"2020","journal-title":"Virology"},{"key":"10.1016\/j.fsi.2024.109991_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108785","article-title":"CD4-1 and CD4-2 single positive are two major CD4 lymphocyte subpopulations in ginbuna crucian carp Carassius auratus langsdorfii","volume":"138","author":"Lau","year":"2023","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2024.109991_bib47","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.3390\/v12121354","article-title":"Evasion of the cell-mediated immune response by alphaherpesviruses","volume":"12","author":"Koyanagi","year":"2020","journal-title":"Viruses"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464824006363?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464824006363?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T23:57:19Z","timestamp":1752623839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464824006363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":47,"alternative-id":["S1050464824006363"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2024.109991","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cell-mediated and humoral immune responses of cyprinids induced by a live attenuated vaccine against cyprinid herpesvirus 2 infection in comparison to the virus non-permissive high temperature water treatment","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2024.109991","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"109991"}}