{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T02:17:58Z","timestamp":1789438678103,"version":"build-2803163510"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515110481"],"award-info":[{"award-number":["2021A1515110481"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515010537"],"award-info":[{"award-number":["2024A1515010537"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A20255"],"award-info":[{"award-number":["U23A20255"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31972818"],"award-info":[{"award-number":["31972818"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.fsi.2025.110426","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T19:08:38Z","timestamp":1748459318000},"page":"110426","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Identification and characterization of interferon regulatory factor 8 (IRF8) in Nile tilapia (Oreochromis niloticus)"],"prefix":"10.1016","volume":"165","author":[{"given":"Huaqing","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingxi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4452-7678","authenticated-orcid":false,"given":"Jianmin","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2025.110426_bib1","doi-asserted-by":"crossref","first-page":"3711","DOI":"10.4049\/jimmunol.156.10.3711","article-title":"Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation","volume":"156","author":"Nelson","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1119(99)00262-0","article-title":"Interferon regulatory factors: the next generation","volume":"237","author":"Mamane","year":"1999","journal-title":"Gene"},{"key":"10.1016\/j.fsi.2025.110426_bib3","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.dci.2017.11.015","article-title":"Composition and transcription of all interferon regulatory factors (IRFs), IRF1\u201211 in a perciform fish, the mandarin fish, Siniperca chuatsi","volume":"81","author":"Laghari","year":"2018","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib4","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.1128\/MCB.22.11.3942-3957.2002","article-title":"A novel interferon regulatory factor (IRF), IRF-10, has a unique role in immune defense and is induced by the v-Rel oncoprotein","volume":"22","author":"Nehyba","year":"2002","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.fsi.2025.110426_bib5","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1471-2172-11-22","article-title":"Global characterization of interferon regulatory factor (IRF) genes in vertebrates: glimpse of the diversification in evolution","volume":"11","author":"Huang","year":"2010","journal-title":"BMC Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib6","doi-asserted-by":"crossref","first-page":"237","DOI":"10.4049\/jimmunol.2000245","article-title":"Characterization of DNA binding and nuclear retention identifies zebrafish IRF11 as a positive regulator of IFN antiviral response","volume":"205","author":"Zhao","year":"2020","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib7","article-title":"Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences","volume":"18","author":"Yoshifumi","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.fsi.2025.110426_bib8","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S1359-6101(97)00019-1","article-title":"The growing family of interferon regulatory factors","volume":"8","author":"Nguyen","year":"1997","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.fsi.2025.110426_bib9","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1146\/annurev.immunol.19.1.623","article-title":"IRF family of transcription factors as regulators of host defense","volume":"19","author":"Taniguchi","year":"2001","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib10","doi-asserted-by":"crossref","first-page":"6468","DOI":"10.4049\/jimmunol.163.12.6468","article-title":"Protein-protein and DNA-protein interactions affect the activity of lymphoid-specific IFN regulatory factors","volume":"163","author":"Meraro","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib11","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s00262-009-0804-6","article-title":"Regulation of immunity and oncogenesis by the IRF transcription factor family","volume":"59","author":"Savitsky","year":"2010","journal-title":"Cancer Immunol. Immunother."},{"key":"10.1016\/j.fsi.2025.110426_bib12","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s12026-008-8055-8","article-title":"IRF8 regulates myeloid and B lymphoid lineage diversification","volume":"43","author":"Wang","year":"2009","journal-title":"Immunol. Res."},{"key":"10.1016\/j.fsi.2025.110426_bib13","doi-asserted-by":"crossref","first-page":"7417","DOI":"10.4049\/jimmunol.162.12.7417","article-title":"Regulation of IFN consensus sequence binding protein expression in murine macrophages","volume":"162","author":"Kantakamalakul","year":"1999","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib14","doi-asserted-by":"crossref","first-page":"7898","DOI":"10.4049\/jimmunol.177.11.7898","article-title":"IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development","volume":"177","author":"Ma","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib15","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.4049\/jimmunol.174.5.2573","article-title":"IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity","volume":"174","author":"Tamura","year":"2005","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib16","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/978-1-4614-6111-1_3","article-title":"Genetic determinants of susceptibility to Mycobacterial infections: IRF8, a new kid on the block","volume":"783","author":"Salem","year":"2013","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.fsi.2025.110426_bib17","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.immunol.26.021607.090400","article-title":"The IRF family transcription factors in immunity and oncogenesis","volume":"26","author":"Tamura","year":"2008","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib18","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s00439-020-02154-2","article-title":"Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases","volume":"139","author":"Salem","year":"2020","journal-title":"Hum. Genet."},{"key":"10.1016\/j.fsi.2025.110426_bib19","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1084\/jem.190.3.411","article-title":"Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein","volume":"190","author":"Gabriele","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.fsi.2025.110426_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fsi.2019.08.060","article-title":"Functional characterization of IRF8 regulation of type II IFN in golden pompano (Trachinotus ovatus)","volume":"94","author":"Zhu","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib21","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.vetimm.2012.06.008","article-title":"Molecular cloning and expression analysis of interferon regulatory factor 8 (IRF8) in turbot, Scophthalmus maximus","volume":"149","author":"Chen","year":"2012","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.fsi.2025.110426_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2022.104622","article-title":"Characterization and expression analysis of the interferon regulatory factor (IRF) gene family in zig-zag eel (Mastacembelus armatus) against Aeromonas veronii infection","volume":"140","author":"Han","year":"2023","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib23","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.fsi.2015.02.032","article-title":"Characterization and expression analyses of five interferon regulatory factor transcripts (Irf4a, Irf4b, Irf7, Irf8, Irf10) in Atlantic cod (Gadus morhua)","volume":"44","author":"Inkpen","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib24","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.fsi.2013.06.016","article-title":"Structural and expression studies of interferon regulatory factor 8 in Japanese flounder, Paralichthys olivaceus","volume":"35","author":"Hu","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib25","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.fsi.2012.07.017","article-title":"Interferon regulatory factors 4 and 8 in rock bream, Oplegnathus fasciatus: structural and expressional evidence for their antimicrobial role in teleosts","volume":"33","author":"Bathige","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib26","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.fsi.2010.03.001","article-title":"Molecular cloning and characterization of interferon regulatory factors 4 and 8 (IRF-4 and IRF-8) in rainbow trout, Oncorhynchus mykiss","volume":"29","author":"Holland","year":"2010","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib27","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.dci.2017.09.012","article-title":"Expression and functional characterization of interferon regulatory factors 4, 8, and 9 in large yellow croaker (Larimichthys crocea)","volume":"78","author":"Tang","year":"2018","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib28","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.molimm.2021.04.020","article-title":"Grass carp (Ctenopharyngodon idella) interferon regulatory factor 8 down-regulates interferon1 expression via interaction with interferon regulatory factor 2 in vitro","volume":"137","author":"Chang","year":"2021","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib29","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3389\/fimmu.2020.00606","article-title":"IRF3 and IRF8 regulate NF-\u03baB signaling by targeting MyD88 in teleost fish","volume":"11","author":"Yan","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib30","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.858179","article-title":"IRF4b and IRF8 negatively regulate RLR-mediated NF-\u03baB signaling by targeting MITA for degradation in teleost fish","volume":"13","author":"Yan","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0117513","article-title":"Differential requirement for irf8 in formation of embryonic and adult macrophages in zebrafish","volume":"10","author":"Shiau","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.fsi.2025.110426_bib32","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1182\/blood-2010-06-290700","article-title":"Irf8 regulates macrophage versus neutrophil fate during zebrafish primitive myelopoiesis","volume":"117","author":"Li","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.fsi.2025.110426_bib33","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.fsi.2018.09.072","article-title":"Identification and characterization of a B-type mannose-binding lectin from Nile tilapia (Oreochromis niloticus) in response to bacterial infection","volume":"84","author":"Yin","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib34","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.fsi.2017.06.016","article-title":"Identification and characterization of a mannose-binding lectin from Nile tilapia (Oreochromis niloticus)","volume":"67","author":"Mu","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib35","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.3389\/fimmu.2020.01706","article-title":"MAp34 regulates the non-specific cell immunity of monocytes\/macrophages and inhibits the lectin pathway of complement activation in a teleost fish","volume":"11","author":"Mu","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2020.103629","article-title":"Molecular and functional characterization of IL-6 receptor (IL-6R) and glycoprotein 130 (gp130) in Nile tilapia (Oreochromis niloticus)","volume":"106","author":"Zhou","year":"2020","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib37","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.molimm.2018.08.012","article-title":"Expression and functional characterization of collection-K1 from Nile tilapia (Oreochromis niloticus) in host innate immune defense","volume":"103","author":"Mu","year":"2018","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib38","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232415586","article-title":"Complement C3 regulates inflammatory response and monocyte\/macrophage phagocytosis of Streptococcus agalactiae in a teleost fish","volume":"23","author":"Bai","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.fsi.2025.110426_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.738321","article-title":"Study on the expression of Nk-lysin from Nile tilapia (Oreochromis niloticus) in Pichia pastoris and its biological function","volume":"557","author":"Chen","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.110426_bib40","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.fsi.2025.110426_bib41","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/molbev\/msr121","article-title":"MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods","volume":"28","author":"Tamura","year":"2011","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.fsi.2025.110426_bib42","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/978-1-4939-6412-3_13","article-title":"Purification of proteins fused to maltose-binding protein","volume":"1485","author":"Lebendiker","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.fsi.2025.110426_bib43","doi-asserted-by":"crossref","first-page":"801","DOI":"10.4049\/jimmunol.148.3.801","article-title":"Modulation of interferon consensus sequence binding protein mRNA in murine peritoneal macrophages. Induction by IFN-gamma and down-regulation by IFN-alpha, dexamethasone, and protein kinase inhibitors","volume":"148","author":"Politis","year":"1992","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib44","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1073\/pnas.87.10.3743","article-title":"An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes","volume":"87","author":"Driggers","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.fsi.2025.110426_bib45","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/MOH.0000000000000196","article-title":"Interferon regulatory factor 8 and the regulation of neutrophil, monocyte, and dendritic cell production","volume":"23","author":"Y\u00e1\u00f1ez","year":"2016","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.fsi.2025.110426_bib46","doi-asserted-by":"crossref","first-page":"10073","DOI":"10.1074\/jbc.M507788200","article-title":"IRF-8\/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways","volume":"281","author":"Zhao","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.fsi.2025.110426_bib47","doi-asserted-by":"crossref","first-page":"6820","DOI":"10.4049\/jimmunol.172.11.6820","article-title":"Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8\/IFN consensus sequence binding protein in dendritic cells","volume":"172","author":"Tsujimura","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib48","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.cytogfr.2014.10.011","article-title":"Type I IFN family members: similarity, differences and interaction","volume":"26","author":"Capobianchi","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.fsi.2025.110426_bib49","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3389\/fimmu.2018.01105","article-title":"Mechanisms of fish macrophage antimicrobial immunity","volume":"9","author":"Grayfer","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2025.110426_bib50","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.immuni.2006.08.009","article-title":"Type I interferon gene induction by the interferon regulatory factor family of transcription factors","volume":"25","author":"Honda","year":"2006","journal-title":"Immunity"},{"key":"10.1016\/j.fsi.2025.110426_bib51","doi-asserted-by":"crossref","first-page":"3474","DOI":"10.4049\/jimmunol.181.5.3474","article-title":"Teleost TLR22 recognizes RNA duplex to induce IFN and protect cells from birnaviruses","volume":"181","author":"Matsuo","year":"2008","journal-title":"J. Immunol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464825003158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464825003158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T19:34:12Z","timestamp":1772048052000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464825003158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":51,"alternative-id":["S1050464825003158"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2025.110426","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification and characterization of interferon regulatory factor 8 (IRF8) in Nile tilapia (Oreochromis niloticus)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2025.110426","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"110426"}}