{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T06:01:59Z","timestamp":1782626519720,"version":"3.54.5"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018685","name":"Shanxi Province Foundation for Returness","doi-asserted-by":"publisher","award":["2016\\u20131"],"award-info":[{"award-number":["2016\\u20131"]}],"id":[{"id":"10.13039\/501100018685","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011182","name":"Institute of Hydrobiology, Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011182","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31672293"],"award-info":[{"award-number":["31672293"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.fsi.2025.110485","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T11:55:34Z","timestamp":1749470134000},"page":"110485","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Effect of cadmium on the gene transcription regulation function of nuclear transcription factor ShDorsal in the freshwater crab Sinopotamon henanense"],"prefix":"10.1016","volume":"165","author":[{"given":"Minnan","family":"Bao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haichao","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caiping","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuobing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.fsi.2025.110485_bib1","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a000232","article-title":"NF-kappaB in the immune response of Drosophila","volume":"1","author":"Hetru","year":"2009","journal-title":"Cold Spring Harbor Perspect. Biol."},{"issue":"18","key":"10.1016\/j.fsi.2025.110485_bib2","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1101\/gad.1228704","article-title":"Signaling to NF-kappaB","volume":"18","author":"Hayden","year":"2004","journal-title":"Gene Dev."},{"key":"10.1016\/j.fsi.2025.110485_bib3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.fsi.2022.05.054","article-title":"The MRE11 opposes white spot syndrome virus infection through the IRF and Dorsal mediated antiviral pathways in shrimp","volume":"126","author":"Zhu","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib4","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.dci.2019.01.017","article-title":"An in vitro study of NF-\u03baB factors cooperatively in regulation of Drosophila melanogaster antimicrobial peptide genes","volume":"95","author":"Chowdhury","year":"2019","journal-title":"Dev. Comp. Immunol."},{"issue":"5","key":"10.1016\/j.fsi.2025.110485_bib5","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S1074-7613(00)80208-3","article-title":"The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila","volume":"12","author":"Rutschmann","year":"2000","journal-title":"Immunity (Camb., Mass.)"},{"issue":"33","key":"10.1016\/j.fsi.2025.110485_bib6","doi-asserted-by":"crossref","first-page":"14715","DOI":"10.1073\/pnas.1009473107","article-title":"Heterodimers of NF-kappaB transcription factors DIF and Relish regulate antimicrobial peptide genes in Drosophila","volume":"107","author":"Tanji","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib7","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3390\/cells11010152","article-title":"The negative regulative roles of BdPGRPs in the Imd signaling pathway of Bactrocera dorsalis","volume":"11","author":"Zhang","year":"2022","journal-title":"Cells"},{"issue":"2","key":"10.1016\/j.fsi.2025.110485_bib8","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.dci.2009.08.009","article-title":"Identification and functional study of a shrimp Dorsal homologue","volume":"34","author":"Huang","year":"2010","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib9","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.fsi.2018.07.016","article-title":"Identification and functional analysis of immune deficiency (IMD) from Scylla paramamosain: the first evidence of IMD signaling pathway involved in immune defense against bacterial infection in crab species","volume":"81","author":"Zhou","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.dci.2017.04.005","article-title":"The transcription factor Relish controls Anaplasma marginale infection in the bovine tick Rhipicephalus microplus","volume":"74","author":"Peixoto","year":"2017","journal-title":"Dev. Comp. Immunol."},{"issue":"2","key":"10.1016\/j.fsi.2025.110485_bib11","first-page":"298","article-title":"Cloning and expression characteristics of NF-\u03baB-family genes Relish and Dorsal in Portunus trituberculatus","volume":"43","author":"Zhao","year":"2019","journal-title":"Acta Hydrobiol. Sin."},{"issue":"11","key":"10.1016\/j.fsi.2025.110485_bib12","first-page":"1551","article-title":"Cloning of NF-\u03baB-family genes and their expression changes during bacterial infection in Fenneropenaeus penicillatus","volume":"29","author":"Liang","year":"2022","journal-title":"J. Fish. Sci. China"},{"issue":"8","key":"10.1016\/j.fsi.2025.110485_bib13","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1111\/jfd.13374","article-title":"Toll protein family structure, evolution and response of the whiteleg shrimp (Litopenaeus vannamei) to exogenous iridescent virus","volume":"44","author":"Liu","year":"2021","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.fsi.2025.110485_bib14","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.fsi.2019.07.026","article-title":"The white spot syndrome virus hijacks the expression of the Penaeus vannamei Toll signaling pathway to evade host immunity and facilitate its replication","volume":"92","author":"Garc\u00eda","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib15","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.gene.2017.09.060","article-title":"Toll-receptor 9 gene in the black tiger shrimp (Penaeus monodon) induced the activation of the TLR\u2013NF-\u03baB signaling pathway","volume":"639","author":"Liu","year":"2018","journal-title":"Gene (Amst.)"},{"issue":"9","key":"10.1016\/j.fsi.2025.110485_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007109","article-title":"RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides","volume":"14","author":"Li","year":"2018","journal-title":"PLoS Pathog."},{"issue":"10","key":"10.1016\/j.fsi.2025.110485_bib17","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.4049\/jimmunol.2200476","article-title":"The Drosophila Toll pathway in innate immunity: from the core pathway toward effector functions","volume":"209","author":"Valanne","year":"2022","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2021.104183","article-title":"lncRNA-CR46018 positively regulates the Drosophila Toll immune response by interacting with Dif\/Dorsal","volume":"124","author":"Zhou","year":"2021","journal-title":"Dev. Comp. Immunol."},{"issue":"8","key":"10.1016\/j.fsi.2025.110485_bib19","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.dci.2010.03.008","article-title":"A Dorsal homolog (FcDorsal) in the Chinese shrimp Fenneropenaeus chinensis is responsive to both bacteria and WSSV challenge","volume":"34","author":"Li","year":"2010","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib20","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.fsi.2016.07.039","article-title":"The Dorsal\/miR-1959\/Cactus feedback loop facilitates the infection of WSSV in Litopenaeus vannamei","volume":"56","author":"Xu","year":"2016","journal-title":"Fish Shellfish Immunol."},{"issue":"4","key":"10.1016\/j.fsi.2025.110485_bib21","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.dci.2013.08.013","article-title":"Molecular cloning and expression analysis of a dorsal homologue from Eriocheir sinensis","volume":"41","author":"Yu","year":"2013","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2019.103581","article-title":"The NF-\u03baB family member dorsal plays a role in immune response against Gram-positive bacterial infection in mud crab (Scylla paramamosain)","volume":"106","author":"Deng","year":"2020","journal-title":"Dev. Comp. Immunol."},{"issue":"12","key":"10.1016\/j.fsi.2025.110485_bib23","doi-asserted-by":"crossref","first-page":"8829","DOI":"10.1007\/s10653-023-01535-6","article-title":"Modeling and identification of affective parameters on Cd's durability and evaluating Cd pollution indicators caused by using chemical fertilizers in long term","volume":"45","author":"Rahimi","year":"2023","journal-title":"Environ. Geochem. Health"},{"key":"10.1016\/j.fsi.2025.110485_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114762","article-title":"Identification of acid phosphatase (ShACP) from the freshwater crab Sinopotamon henanense and its expression pattern changes in response to Cd","volume":"255","author":"Sang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.fsi.2025.110485_bib25","series-title":"The Immunotoxic Effect of Cd on Sinopotamon Henanense [D]","author":"Qin","year":"2011"},{"key":"10.1016\/j.fsi.2025.110485_bib26","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.fsi.2017.10.013","article-title":"Identification of a novel toll gene (Shtoll3) from the freshwater crab Sinopotamon henanense and its expression pattern changes in response to Cd followed by Aeromonas hydrophila infection","volume":"71","author":"Lang","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib27","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.fsi.2020.01.012","article-title":"Clone, identification and functional characterization of a novel toll (Shtoll1) from the freshwater crab Sinopotamon henanense in response to Cd exposure and Aeromonas hydrophila infection","volume":"98","author":"Lang","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2025.110485_bib28","series-title":"Effects of Cd Exposure on Vasa and its Action Pathway Molecules in Sinopotamon Henanense [D]","author":"Liu","year":"2020"},{"issue":"3","key":"10.1016\/j.fsi.2025.110485_bib29","first-page":"388","article-title":"Functional domains in the Toll and IMD signaling pathways of Drosophila melanogaster","volume":"33","author":"Liu","year":"2011","journal-title":"J. Environ. Insects"},{"key":"10.1016\/j.fsi.2025.110485_bib30","series-title":"Study on the Immune Function of Lectin, Dorsal and Ras in Main Economic Shrimps [D]","author":"Huang","year":"2018"},{"key":"10.1016\/j.fsi.2025.110485_bib31","series-title":"Study on the Immunotoxic Effect of Cd Induced Sinanodonta Woodiana [D]","author":"Ren","year":"2018"},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.jece.2021.106912","article-title":"Remediation of as and Cd contaminated sediment by biochars: accompanied with the change of microbial community","volume":"10","author":"Gu","year":"2022","journal-title":"J. Environ. Chem. Eng."},{"issue":"46","key":"10.1016\/j.fsi.2025.110485_bib33","doi-asserted-by":"crossref","first-page":"66072","DOI":"10.1007\/s11356-021-15636-1","article-title":"Distribution and assessment of Cd contamination in sediments from the four river inlets to dongting lake, China","volume":"28","author":"Wu","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib34","article-title":"Pollution of water with lead and Cd by the effect of adding cities waste in al-diwaniyah river, Iraq","volume":"735","author":"Shaalan","year":"2021","journal-title":"IOP Conf. Ser. Earth Environ. Sci."},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib35","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s00128-020-03088-1","article-title":"A review on Cd exposure in the population and intervention strategies against Cd Toxicity","volume":"106","author":"Wang","year":"2021","journal-title":"Bull. Environ. Contam. Toxicol."},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib36","article-title":"Farmer awareness to the dangers of heavy metal Cd Cd Pollution due to overfertilization in sragen regency central java","volume":"34","author":"Pradika","year":"2019","journal-title":"Caraka Tani: J. Sustain. Agric."},{"issue":"6","key":"10.1016\/j.fsi.2025.110485_bib37","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/j.ecolind.2010.03.016","article-title":"Impacts of Cd contamination and fish presence on wetland invertebrate communities: an application of population measures and multi-metric tests","volume":"10","author":"Taylor","year":"2010","journal-title":"Ecol. Indic."},{"issue":"S1","key":"10.1016\/j.fsi.2025.110485_bib38","first-page":"96","article-title":"Accumulation of Cd in five tissues and organs of Eriocheir sinensis and its effect on esterase Isozyme","author":"Wang","year":"2001","journal-title":"Acta Zool."},{"issue":"6","key":"10.1016\/j.fsi.2025.110485_bib39","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1002\/alr.21705","article-title":"Cd induces mucin 8 expression via Toll-like receptor 4-mediated extracellular signal related kinase 1\/2 and p38 mitogen-activated protein kinase in human airway epithelial cells","volume":"6","author":"Song","year":"2016","journal-title":"Int. Forum Aller. Rhinol."},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib40","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3390\/ijerph17010138","article-title":"Cd induces acute liver injury by inhibiting Nrf2 and the role of NF-\u03baB, NLRP3, and MAPKs signaling pathway","volume":"17","author":"Liu","year":"2019","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.fsi.2025.110485_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.peptides.2022.170896","article-title":"Recent articles highlighting the multifunctional character and wider therapeutic potential of antimicrobial peptides","volume":"158","author":"Conlon","year":"2022","journal-title":"Peptides"},{"issue":"19","key":"10.1016\/j.fsi.2025.110485_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/ijms231911505","article-title":"Characterization of new defensin antimicrobial peptides and their expression in bed bugs in response to bacterial ingestion and injection","volume":"23","author":"Meraj","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"21","key":"10.1016\/j.fsi.2025.110485_bib43","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20215426","article-title":"Blood compatibility\u2014an important but often forgotten aspect of the characterization of antimicrobial peptides for clinical application","volume":"20","author":"Harm","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10989-021-10325-6","article-title":"A review of antimicrobial peptides: its function, mode of action and therapeutic potential","volume":"28","author":"Nayab","year":"2022","journal-title":"Int. J. Pept. Res. Therapeut."},{"issue":"11","key":"10.1016\/j.fsi.2025.110485_bib45","first-page":"801","article-title":"A review on the use of antimicrobial peptides to combat porcine viruses","volume":"9","author":"Pen","year":"2020","journal-title":"Antibiotics (Basel, Switzerland)"},{"key":"10.1016\/j.fsi.2025.110485_bib46","article-title":"Antibacterial activity and immunomodulatory role of a proline-rich antimicrobial peptide SpPR-AMP1 against Vibrio campbellii infection in shrimp Litopenaeus vannamei","volume":"132","author":"Phuket","year":"2023","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib47","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3390\/genes11010093","article-title":"Shedding light on the antimicrobial peptide arsenal of terrestrial isopods: focus on armadillidins, a new crustacean AMP family","volume":"11","author":"Becking","year":"2020","journal-title":"Genes"},{"key":"10.1016\/j.fsi.2025.110485_bib48","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.dci.2018.03.016","article-title":"First characterization of an anti-lipopolysaccharide factor (ALF) from hydrothermal vent shrimp: insights into the immune function of deep-sea crustacean ALF","volume":"84","author":"Gu","year":"2018","journal-title":"Dev. Comp. Immunol."},{"issue":"2","key":"10.1016\/j.fsi.2025.110485_bib49","first-page":"594","article-title":"On the silver jubilee of crustacean antimicrobial peptides","volume":"14","author":"Machado","year":"2021","journal-title":"Rev. Aquacult."},{"issue":"7","key":"10.1016\/j.fsi.2025.110485_bib50","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1016\/j.molimm.2007.10.039","article-title":"Anti-lipopolysaccharide factor in Litopenaeus vannamei (LvALF): a broad spectrum antimicrobial peptide essential for shrimp immunity against bacterial and fungal infection","volume":"45","author":"Vega","year":"2008","journal-title":"Mol. Immunol."},{"issue":"18","key":"10.1016\/j.fsi.2025.110485_bib51","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221810117","article-title":"LncRNA-CR11538 Decoys Dif\/Dorsal to reduce antimicrobial peptide products for restoring Drosophila Toll immunity homeostasis","volume":"22","author":"Zhou","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"26","key":"10.1016\/j.fsi.2025.110485_bib52","doi-asserted-by":"crossref","first-page":"10172","DOI":"10.1074\/jbc.RA118.006804","article-title":"Toll family members bind multiple Sp\u00e4tzle proteins and activate antimicrobial peptide gene expression in Drosophila","volume":"294","author":"Chowdhury","year":"2019","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.fsi.2025.110485_bib53","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.fsi.2014.12.038","article-title":"A novel vertebrates Toll-like receptor counterpart regulating the anti-microbial peptides expression in the freshwater crayfish, Procambarus clarkii","volume":"43","author":"Wang","year":"2015","journal-title":"Fish Shellfish Immunol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464825003742?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464825003742?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T19:49:40Z","timestamp":1772048980000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464825003742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":53,"alternative-id":["S1050464825003742"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2025.110485","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of cadmium on the gene transcription regulation function of nuclear transcription factor ShDorsal in the freshwater crab Sinopotamon henanense","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2025.110485","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"110485"}}