{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:03:55Z","timestamp":1793048635640,"version":"4.5.0"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31600322"],"award-info":[{"award-number":["31600322"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013115","name":"Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents","doi-asserted-by":"publisher","award":["WJW2021002"],"award-info":[{"award-number":["WJW2021002"]}],"id":[{"id":"10.13039\/501100013115","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515010453"],"award-info":[{"award-number":["2021A1515010453"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.fsi.2025.111023","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T22:58:20Z","timestamp":1763765900000},"page":"111023","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["A novel Vibrio parahaemolyticus strain JM20210818 causing glass post-larvae disease in Litopenaeus vannamei: Histopathology, antimicrobial resistance, genomic and transcriptomic insights"],"prefix":"10.1016","volume":"169","author":[{"given":"Cong","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guowei","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengwei","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingming","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8154-1516","authenticated-orcid":false,"given":"Lanfen","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2025.111023_bib1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.rvsc.2022.01.009","article-title":"Shrimp production, the most important diseases that threaten it, and the role of probiotics in confronting these diseases: a review","volume":"144","author":"El-Saadony","year":"2022","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.fsi.2025.111023_bib2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/raq.12104","article-title":"Physiological change and nutritional requirement of Pacific white shrimpLitopenaeus vannameiat low salinity","volume":"9","author":"Li","year":"2017","journal-title":"Rev. Aquacult."},{"key":"10.1016\/j.fsi.2025.111023_bib3","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0044-8486(03)00220-5","article-title":"Acute toxicity of nitrite on Litopenaeus vannamei (Boone) juveniles at different salinity levels","volume":"224","author":"Lin","year":"2003","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.jip.2020.107369","article-title":"How do abiotic environmental conditions influence shrimp susceptibility to disease? A critical analysis focussed on White Spot Disease","volume":"186","author":"Millard","year":"2021","journal-title":"J. Invertebr. Pathol."},{"key":"10.1016\/j.fsi.2025.111023_bib5","article-title":"Vaccination trials against vibriosis in shrimp: a review","volume":"18","author":"Amatul-Samahah","year":"2020","journal-title":"Aquacult. Rep."},{"key":"10.1016\/j.fsi.2025.111023_bib6","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.aquaculture.2019.02.055","article-title":"Evaluation on the genomic selection in Litopenaeus vannamei for the resistance against Vibrio parahaemolyticus","volume":"505","author":"Wang","year":"2019","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib7","article-title":"Asian Shrimp production and the economic costs of disease","volume":"31S","author":"Shinn","year":"2018","journal-title":"Asian Fish Sci."},{"key":"10.1016\/j.fsi.2025.111023_bib8","doi-asserted-by":"crossref","first-page":"741","DOI":"10.3390\/pathogens9090741","article-title":"Determination of the infectious agent of Translucent Post-Larva disease (TPD) in Penaeus vannamei","volume":"9","author":"Zou","year":"2020","journal-title":"Pathogens"},{"key":"10.1016\/j.fsi.2025.111023_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.737605","article-title":"Highly lethal Vibrio parahaemolyticus strains cause acute mortality in Penaeus vannamei post-larvae","volume":"548","author":"Yang","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.737120","article-title":"Isolation and characterisation of a novel rhabdovirus from snakehead fish showing surface ulcerations and mortality from India: first report","volume":"544","author":"John","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib11","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.aquaculture.2016.10.038","article-title":"Isolation, identification and characterization of Shewanella algae from reared tongue sole, Cynoglossus semilaevis G\u00fcnther","volume":"468","author":"Han","year":"2017","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2020.735284","article-title":"Genomic and histopathological characteristics of Vibrio parahaemolyticus isolated from an acute hepatopancreatic necrosis disease outbreak in Pacific white shrimp (Penaeus vannamei) cultured in Korea","volume":"524","author":"Han","year":"2020","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib13","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/lam.12372","article-title":"Genetic variation in Vibrio parahaemolyticus isolated from the aquacultural environments","volume":"60","author":"Tey","year":"2015","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib14","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3354\/dao02906","article-title":"Genotyping of virulence plasmid from Vibrio parahaemolyticus isolates causing acute hepatopancreatic necrosis disease in shrimp","volume":"115","author":"Han","year":"2015","journal-title":"Dis. Aquat. Organ."},{"key":"10.1016\/j.fsi.2025.111023_bib15","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.aqrep.2015.10.002","article-title":"AP4 method for two-tube nested PCR detection of AHPND isolates of Vibrio parahaemolyticus","volume":"2","author":"Dangtip","year":"2015","journal-title":"Aquacult. Rep."},{"key":"10.1016\/j.fsi.2025.111023_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.736608","article-title":"Antimicrobial resistance and virulence characteristics of Vibrio vulnificus, Vibrio parahaemolyticus and Vibrio harveyi from natural disease outbreaks of marine\/estuarine fishes","volume":"539","author":"Sony","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib17","article-title":"The Vibrio-predatory filamentous bacteria effectively removed acute hepatopancreatic necrosis disease (AHPND) causative Vibrio parahaemolyticus in vitro","volume":"21","author":"Yeoh","year":"2021","journal-title":"Aquacult. Rep."},{"key":"10.1016\/j.fsi.2025.111023_bib18","first-page":"10798","volume":"112","author":"Lee","year":"2015"},{"key":"10.1016\/j.fsi.2025.111023_bib19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3354\/dao02621","article-title":"Determination of the infectious nature of the agent of acute hepatopancreatic necrosis syndrome affecting penaeid shrimp","volume":"105","author":"Tran","year":"2013","journal-title":"Dis. Aquat. Organ."},{"key":"10.1016\/j.fsi.2025.111023_bib20","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.3389\/fmicb.2019.02305","article-title":"Microbial metabolic capacity for intestinal folate production and modulation of host folate receptors","volume":"10","author":"Engevik","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib21","doi-asserted-by":"crossref","first-page":"2936","DOI":"10.1038\/s41467-020-16747-y","article-title":"A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites","volume":"11","author":"Reich","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.fsi.2025.111023_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1098386","article-title":"Role of gut microbiota in infectious and inflammatory diseases","volume":"14","author":"Maciel-Fiuza","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib23","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1089\/ars.2012.5149","article-title":"Reactive oxygen species in inflammation and tissue injury","volume":"20","author":"Mittal","year":"2014","journal-title":"Antioxid. Redox. Sign."},{"key":"10.1016\/j.fsi.2025.111023_bib24","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41580-020-00324-8","article-title":"Ferroptosis: mechanisms, biology and role in disease","volume":"22","author":"Jiang","year":"2021","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.fsi.2025.111023_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221910431","article-title":"PPARgamma and TGFbeta-Major regulators of metabolism, inflammation, and fibrosis in the lungs and kidneys","volume":"22","author":"Kokeny","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.fsi.2025.111023_bib26","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.fsi.2021.08.006","article-title":"Anti-vibrio and immune-enhancing activity of medicinal plants in shrimp: a comprehensive review","volume":"117","author":"Ghosh","year":"2021","journal-title":"Fish Shellfish Immun."},{"key":"10.1016\/j.fsi.2025.111023_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0044-8486(90)90173-K","article-title":"Occurrence of luminous bacterial disease of Penaeus monodon larvae in the Philippines","volume":"91","author":"Lavilla-Pitogo","year":"1990","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib28","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.gdata.2016.08.008","article-title":"Draft genome sequence of pathogenic bacteria Vibrio parahaemolyticus strain Ba94C2, associated with acute hepatopancreatic necrosis disease isolate from South America","volume":"9","author":"Restrepo","year":"2016","journal-title":"Genom. Data"},{"key":"10.1016\/j.fsi.2025.111023_bib29","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3354\/dao02776","article-title":"Detection of acute hepatopancreatic necrosis disease (AHPND) in Mexico","volume":"111","author":"Nunan","year":"2014","journal-title":"Dis. Aquat. Organ."},{"key":"10.1016\/j.fsi.2025.111023_bib30","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.aquaculture.2014.03.030","article-title":"Variation in Vibrio parahaemolyticus isolates from a single Thai shrimp farm experiencing an outbreak of acute hepatopancreatic necrosis disease (AHPND)","volume":"428\u2013429","author":"Joshi","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib31","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.aquaculture.2018.06.042","article-title":"Experimental methodologies and diagnostic procedures for acute hepatopancreatic necrosis disease (AHPND)","volume":"499","author":"Devadas","year":"2019","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2020.734994","article-title":"Genetic (co)variation in resistance of Pacific white shrimp Litopenaeus vannamei to acute hepatopancreatic necrosis disease (AHPND) and white spot syndrome virus (WSSV) in challenge tests","volume":"520","author":"Campos-Montes","year":"2020","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib33","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3354\/dao03330","article-title":"First report of acute hepatopancreatic necrosis disease (AHPND) occurring in the USA","volume":"132","author":"Dhar","year":"2019","journal-title":"Dis. Aquat. Organ."},{"key":"10.1016\/j.fsi.2025.111023_bib34","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.13127","article-title":"Bile acid and bile acid transporters are involved in the pathogenesis of acute hepatopancreatic necrosis disease in white shrimp Litopenaeus vannamei","volume":"22","author":"Kumar","year":"2020","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib35","doi-asserted-by":"crossref","DOI":"10.3390\/toxins11120717","article-title":"PirAB(VP) toxin binds to epithelial cells of the digestive tract and produce pathognomonic AHPND lesions in germ-free brine shrimp","volume":"11","author":"Kumar","year":"2019","journal-title":"Toxins"},{"key":"10.1016\/j.fsi.2025.111023_bib36","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3354\/dao02830","article-title":"Photorhabdus insect-related (Pir) toxin-like genes in a plasmid of Vibrio parahaemolyticus, the causative agent of acute hepatopancreatic necrosis disease (AHPND) of shrimp","volume":"113","author":"Han","year":"2015","journal-title":"Dis. Aquat. Organ."},{"issue":"1","key":"10.1016\/j.fsi.2025.111023_bib37","article-title":"Shrimp AHPND-causing plasmids encoding the PirAB toxins as mediated by pirAB-Tn903 are prevalent in various Vibrio species","volume":"7","author":"Xiao","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fsi.2025.111023_bib38","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.3389\/fmicb.2017.01859","article-title":"pirABvp-Bearing Vibrio parahaemolyticus and Vibrio campbellii pathogens isolated from the same AHPND-Affected pond possess highly similar pathogenic plasmids","volume":"8","author":"Dong","year":"2017","journal-title":"Front. Microbiol."},{"issue":"3","key":"10.1016\/j.fsi.2025.111023_bib39","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3390\/pathogens9030182","article-title":"The B subunit of PirABvp toxin secreted from Vibrio parahaemolyticus causing AHPND is an amino sugar specific lectin","volume":"9","author":"Victorio-De Los Santos","year":"2020","journal-title":"Pathogens"},{"issue":"5","key":"10.1016\/j.fsi.2025.111023_bib40","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.3390\/microorganisms11051197","article-title":"Pathogenic and opportunistic Vibrio spp. associated with vibriosis incidences in the Greek aquaculture: the role of Vibrio harveyi as the principal cause of vibriosis","volume":"11","author":"Triga","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.fsi.2025.111023_bib41","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3389\/fmicb.2014.00705","article-title":"Vibrio parahaemolyticus: a review on the pathogenesis, prevalence, and advance molecular identification techniques","volume":"5","author":"Letchumanan","year":"2014","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib42","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.micres.2019.03.003","article-title":"Molecular mechanisms of Vibrio parahaemolyticus pathogenesis","volume":"222","author":"Li","year":"2019","journal-title":"Microbiol. Res."},{"issue":"11","key":"10.1016\/j.fsi.2025.111023_bib43","doi-asserted-by":"crossref","first-page":"2752","DOI":"10.3390\/microorganisms11112752","article-title":"Comparative genomic analysis of shrimp-pathogenic Vibrio parahaemolyticus LC and intraspecific strains with emphasis on virulent factors of Mobile genetic elements","volume":"11","author":"Xue","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.fsi.2025.111023_bib44","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00153-17","article-title":"A bacterial stress response regulates respiratory protein complexes to control envelope stress adaptation","volume":"199","author":"Guest","year":"2017","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.fsi.2025.111023_bib45","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.mib.2008.02.016","article-title":"Regulation of bacterial RNA polymerase sigma factor activity: a structural perspective","volume":"11","author":"Campbell","year":"2008","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib46","article-title":"Phenotypic and genomic characterization of a Vibrio parahaemolyticus strain causing disease in Penaeus vannamei provides insights into its niche adaptation and pathogenic mechanism","volume":"7","author":"Zhang","year":"2021","journal-title":"Microb. Genom."},{"key":"10.1016\/j.fsi.2025.111023_bib47","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.micres.2018.07.002","article-title":"Role of two-component regulatory systems in the virulence of Streptococcus suis","volume":"214","author":"Zheng","year":"2018","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.fsi.2025.111023_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.micres.2017.01.005","article-title":"Two-component regulatory system ActS\/ActR is required for Sinorhizobium meliloti adaptation to oxidative stress","volume":"198","author":"Tang","year":"2017","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.fsi.2025.111023_bib49","doi-asserted-by":"crossref","first-page":"557","DOI":"10.3390\/ijms17040557","article-title":"Genome sequence of the fish pathogen Yersinia ruckeri SC09 provides insights into niche adaptation and pathogenic mechanism","volume":"17","author":"Liu","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.fsi.2025.111023_bib50","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1111\/j.1365-2672.2005.02583.x","article-title":"Haemolysins in Vibrio species","volume":"98","author":"Zhang","year":"2005","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib51","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.aquaculture.2011.12.012","article-title":"Vibrio alginolyticus thermolabile hemolysin (TLH) induces apoptosis, membrane vesiculation and necrosis in sea bream erythrocytes","volume":"330\u2013333","author":"Wong","year":"2012","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2025.111023_bib52","doi-asserted-by":"crossref","first-page":"8187","DOI":"10.1007\/s00253-020-10794-7","article-title":"Motility of Vibrio spp.: regulation and controlling strategies","volume":"104","author":"Khan","year":"2020","journal-title":"Appl. Microbiol. Biot."},{"key":"10.1016\/j.fsi.2025.111023_bib53","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms8060815","article-title":"Salmonella heterogeneously expresses flagellin during colonization of plants","volume":"8","author":"Zarkani","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.fsi.2025.111023_bib54","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.micres.2019.03.003","article-title":"Molecular mechanisms of Vibrio parahaemolyticus pathogenesis","volume":"222","author":"Li","year":"2019","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.fsi.2025.111023_bib55","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.micinf.2011.06.013","article-title":"Vibrio parahaemolyticus cell biology and pathogenicity determinants","volume":"13","author":"Broberg","year":"2011","journal-title":"Microbes Infect."},{"key":"10.1016\/j.fsi.2025.111023_bib56","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s40659-015-0064-1","article-title":"The expression of heterologous MAM-7 in Lactobacillus rhamnosus reduces its intrinsic capacity to inhibit colonization of pathogen Vibrio parahaemolyticus in vitro","volume":"49","author":"Beltran","year":"2016","journal-title":"Biol. Res."},{"key":"10.1016\/j.fsi.2025.111023_bib57","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.ijmm.2013.07.010","article-title":"The MSHA pilus of Vibrio parahaemolyticus has lectin functionality and enables TTSS-mediated pathogenicity","volume":"303","author":"O'Boyle","year":"2013","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib58","doi-asserted-by":"crossref","first-page":"5437","DOI":"10.1038\/s41467-019-13301-3","article-title":"Core architecture of a bacterial type II secretion system","volume":"10","author":"Chernyatina","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.fsi.2025.111023_bib59","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.tim.2012.02.007","article-title":"Bacterial effector interplay: a new way to view effector function","volume":"20","author":"Shames","year":"2012","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.fsi.2025.111023_bib60","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.148833","article-title":"The utility of transcriptomics in fish conservation","volume":"221","author":"Connon","year":"2018","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.fsi.2025.111023_bib61","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1146\/annurev-immunol-032713-120236","article-title":"Metabolic regulation of immune responses","volume":"32","author":"Ganeshan","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.fsi.2025.111023_bib62","doi-asserted-by":"crossref","DOI":"10.3390\/biom14060634","article-title":"The peroxisome proliferator-activated receptors of ray-finned fish: unique structures, elusive functions","volume":"14","author":"Boukouvala","year":"2024","journal-title":"Biomolecules"},{"key":"10.1016\/j.fsi.2025.111023_bib63","doi-asserted-by":"crossref","first-page":"5794","DOI":"10.3390\/ijms22115794","article-title":"The role of IL-17-Producing cells in cutaneous fungal infections","volume":"22","author":"Sawada","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.fsi.2025.111023_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113529","article-title":"Effects of early florfenicol exposure on glutathione signaling pathway and PPAR signaling pathway in chick liver","volume":"237","author":"Liu","year":"2022","journal-title":"Ecotox. Environ. Safe"},{"issue":"5","key":"10.1016\/j.fsi.2025.111023_bib65","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1007\/s10646-021-02408-3","article-title":"FABP regulates fatty acid metabolism and oxidative response via PPARalpha\/RXR signaling in Litopenaeus vannamei following environmental exposure of clofibric acid","volume":"30","author":"Zhao","year":"2021","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.fsi.2025.111023_bib66","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.ceb.2014.11.002","article-title":"PPARs and ERRs: molecular mediators of mitochondrial metabolism","volume":"33","author":"Fan","year":"2015","journal-title":"Curr. Opin. Cell Biol."},{"issue":"1","key":"10.1016\/j.fsi.2025.111023_bib67","doi-asserted-by":"crossref","first-page":"102","DOI":"10.3390\/metabo13010102","article-title":"PPAR signaling maintains metabolic homeostasis under hypothermia in freshwater Drum (Aplodinotus grunniens)","volume":"13","author":"Wu","year":"2023","journal-title":"Metabolites"},{"key":"10.1016\/j.fsi.2025.111023_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118356","article-title":"Curculigoside inhibits ferroptosis in ulcerative colitis through the induction of GPX4","volume":"259","author":"Wang","year":"2020","journal-title":"Life Sci."},{"issue":"Pt B","key":"10.1016\/j.fsi.2025.111023_bib69","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.biochi.2023.07.006","article-title":"Responses and modulation of the white shrimp Litopenaeus vannamei glutathione peroxidases 2 and 4 during hypoxia, reoxygenation and GPx4 knock-down","volume":"214","author":"Estrada-Cardenas","year":"2023","journal-title":"Biochimie"},{"key":"10.1016\/j.fsi.2025.111023_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.153245","article-title":"Responses of lipid metabolism and lipidomics in the hepatopancreas of Pacific white shrimp Litopenaeus vannamei to microcystin-LR exposure","volume":"820","author":"Duan","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"2","key":"10.1016\/j.fsi.2025.111023_bib71","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/s41422-020-00441-1","article-title":"Ferroptosis: molecular mechanisms and health implications","volume":"31","author":"Tang","year":"2021","journal-title":"Cell Res."},{"key":"10.1016\/j.fsi.2025.111023_bib72","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0117617","article-title":"Use of 16S rRNA gene for identification of a broad range of clinically relevant bacterial pathogens","volume":"10","author":"Srinivasan","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.fsi.2025.111023_bib73","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1099\/ijs.0.64462-0","article-title":"Phylogenetic analysis of Helicobacter species based on partial gyrB gene sequences","volume":"57","author":"Hannula","year":"2007","journal-title":"Int. J. Syst. Evol. Micr."},{"key":"10.1016\/j.fsi.2025.111023_bib74","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00492-23","article-title":"Vibrio parahaemolyticus becomes lethal to post-larvae shrimp via acquiring novel virulence factors","volume":"11","author":"Liu","year":"2023","journal-title":"Microbiol. Spectr."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105046482500912X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105046482500912X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:04:37Z","timestamp":1773828277000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S105046482500912X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":74,"alternative-id":["S105046482500912X"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2025.111023","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel Vibrio parahaemolyticus strain JM20210818 causing glass post-larvae disease in Litopenaeus vannamei: Histopathology, antimicrobial resistance, genomic and transcriptomic insights","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2025.111023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111023"}}