{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T10:08:24Z","timestamp":1776161304463,"version":"3.50.1"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100010166","name":"Xiamen Municipal Bureau of Science and Technology","doi-asserted-by":"publisher","award":["2024CXY0320"],"award-info":[{"award-number":["2024CXY0320"]}],"id":[{"id":"10.13039\/100010166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32172964"],"award-info":[{"award-number":["32172964"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.fsi.2026.111274","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:07:15Z","timestamp":1773421635000},"page":"111274","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Immunological functional studies of a putative lipocalin member LcApoM_AGPRP in large yellow croaker (Larimichthys crocea)"],"prefix":"10.1016","volume":"173","author":[{"given":"Ruyu","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunmei","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingge","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yani","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2535-1897","authenticated-orcid":false,"given":"Dongling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.fsi.2026.111274_bib1","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.repbre.2025.03.006","article-title":"Germplasm innovation of large yellow croaker and its research progress","volume":"5","author":"Liu","year":"2025","journal-title":"Reproduction Breeding."},{"key":"10.1016\/j.fsi.2026.111274_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.126188","article-title":"Seasonal and regional differences of heavy metals and nutrients from the five mariculture areas of large yellow croaker: implications for environmental and fish quality","volume":"374","author":"Chen","year":"2025","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.fsi.2026.111274_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2023.739682","article-title":"The study of the genomic selection of white gill disease resistance in large yellow croaker (Larimichthys crocea)","volume":"574","author":"Zhou","year":"2023","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2026.111274_bib4","article-title":"Characterization of a trypanosome from large yellow croaker (Larimichthys crocea), cage-cultured in seawater, in China","volume":"43","author":"Wang","year":"2025","journal-title":"Aquac. Rep."},{"key":"10.1016\/j.fsi.2026.111274_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2025.743186","article-title":"Pathogenic function of the lafa gene in Vibrio harveyi and its regulatory role in host immune response during infection of large yellow croaker (Larimichthys crocea)","volume":"612","author":"Li","year":"2026","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2026.111274_bib6","doi-asserted-by":"crossref","unstructured":"Q. Chen, Q. Yan, K. Wang, et al., Portal of entry for pathogenic Vibrio alginolyticus into large yellow croaker Pseudosciaena crocea, and characteristics of bacterial adhesion to mucus. Dis. Aquat. Org. 80, 181-188, https:\/\/doi.org\/10.3354\/dao01933.","DOI":"10.3354\/dao01933"},{"key":"10.1016\/j.fsi.2026.111274_bib7","doi-asserted-by":"crossref","unstructured":"G.L. Wang, S.P. Yuan, S. Jin, Nocardiosis in large yellow croaker, Larimichthys crocea (Richardson). J. Fish. Dis. 28, 339-345, https:\/\/doi.org\/10.1111\/j.1365-2761.2005.00637.x.","DOI":"10.1111\/j.1365-2761.2005.00637.x"},{"key":"10.1016\/j.fsi.2026.111274_bib8","doi-asserted-by":"crossref","unstructured":"J.T. Zhang, S.M. Zhou, S.W. An, et al., Visceral granulomas in farmed large yellow croaker, Larimichthys crocea (Richardson), caused by a bacterial pathogen, Pseudomonas plecoglossicida. J. Fish. Dis. 37, 113-121, https:\/\/doi.org\/10.1111\/jfd.12075.","DOI":"10.1111\/jfd.12075"},{"issue":"2","key":"10.1016\/j.fsi.2026.111274_bib9","first-page":"1","article-title":"Antibacterial resistance of vibrio parahaemolyticus isolated from shrimp farms located in east coastal region of the mekong delta, Vietnam CTU","volume":"14","author":"Dang","year":"2022","journal-title":"J. Inno. Sustainable Devel."},{"key":"10.1016\/j.fsi.2026.111274_bib10","series-title":"Antimicrobial Peptides: New Drugs for Bad Bugs? Expert Opinion on Biological Therapy","first-page":"11","author":"Steckbeck","year":"2014"},{"key":"10.1016\/j.fsi.2026.111274_bib11","doi-asserted-by":"crossref","first-page":"109","DOI":"10.3390\/fishes10030109","article-title":"A hypothetical protein fragment from large yellow croaker (Larimichthys crocea) demonstrates significant activity against both bacterial and parasite","volume":"10","author":"Yan","year":"2025","journal-title":"Fishes"},{"issue":"5","key":"10.1016\/j.fsi.2026.111274_bib12","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1093\/molbev\/msg079","article-title":"Exon-intron structure and evolution of the Lipocalin gene family","volume":"20","author":"S\u00e1nchez","year":"2003","journal-title":"Mol. Biol. Evol."},{"issue":"1-2","key":"10.1016\/j.fsi.2026.111274_bib13","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0167-4838(00)00151-5","article-title":"Evolution of the lipocalin family as inferred from a protein sequence phylogeny","volume":"1482","author":"Guti\u00e9rrez","year":"2000","journal-title":"Biochim. Biophys. Acta Protein Struct. Mol. Enzymol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111274_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj3180001","article-title":"The lipocalin protein family: structure and function","volume":"318","author":"Flower","year":"1996","journal-title":"Biochem. J."},{"issue":"1-2","key":"10.1016\/j.fsi.2026.111274_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0167-4838(00)00148-5","article-title":"The lipocalin protein family: structural and sequence overview","volume":"1482","author":"Flower","year":"2000","journal-title":"Biochim. Biophys. Acta Protein Struct. Mol. Enzymol."},{"key":"10.1016\/j.fsi.2026.111274_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetimm.2025.110921","article-title":"Characterization of a lipocalin-like molecule from Dermanyssus gallinae as a potential vaccine antigen","volume":"283","author":"Horio","year":"2025","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.fsi.2026.111274_bib17","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/978-981-15-6082-8_7","article-title":"Research progress and clinical perspective","volume":"1276","author":"Luo","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.fsi.2026.111274_bib18","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1476-511X-3-21","volume":"3","author":"Luo","year":"2004","journal-title":"Lipids Health Dis."},{"issue":"3","key":"10.1016\/j.fsi.2026.111274_bib19","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/s41569-021-00613-5","article-title":"Apolipoproteins in vascular biology and atherosclerotic disease","volume":"19","author":"Mehta","year":"2022","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.fsi.2026.111274_bib20","article-title":"Apolipoprotein M (ApoM) involved in the nile tilapia (Oreochromis niloticus) against Streptococcus agalactiae infection","volume":"39","author":"Tan","year":"2024","journal-title":"Aquac. Rep."},{"issue":"6","key":"10.1016\/j.fsi.2026.111274_bib21","doi-asserted-by":"crossref","first-page":"668","DOI":"10.56093\/ijans.v87i6.71348","article-title":"Apolipoproteins in fish: from lipid transport to innate immunity","volume":"87","author":"Sahoo","year":"2017","journal-title":"Indian J. Anim. Sci."},{"issue":"3","key":"10.1016\/j.fsi.2026.111274_bib22","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1080\/10799893.2021.1924203","article-title":"Regulation of the apolipoprotein M signaling pathway: a review","volume":"42","author":"Cheng","year":"2022","journal-title":"J. Recept. Signal Transduct. Res."},{"key":"10.1016\/j.fsi.2026.111274_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.143187","article-title":"Delineating the intricacies of polymorphisms, structures, functions and therapeutic applications of biological high-density lipoprotein-apolipoprotein M: a review","volume":"310","author":"Yadav","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.fsi.2026.111274_bib24","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1194\/jlr.D055947","article-title":"Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA","volume":"56","author":"Bosteen","year":"2015","journal-title":"JLR (J. Lipid Res.)"},{"issue":"1","key":"10.1016\/j.fsi.2026.111274_bib25","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1161\/ATVBAHA.116.308435","article-title":"High-density lipoprotein-associated apolipoprotein m limits endothelial inflammation by delivering sphingosine-1-phosphate to the sphingosine-1-phosphate receptor 1","volume":"37","author":"Ruiz","year":"2017","journal-title":"Arteriosclerosis. Thrombosis. Vascular Biol"},{"issue":"1","key":"10.1016\/j.fsi.2026.111274_bib26","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3390\/ijms19010112","article-title":"Apolipoprotein m inhibits angiogenic and inflammatory response by sphingosine-1-phosphate on retinal pigment epithelium cells","volume":"19","author":"Terao","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.fsi.2026.111274_bib27","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1359-6101(02)00054-0","article-title":"\u03b11-Acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties","volume":"14","author":"Hochepied","year":"2003","journal-title":"Cytokine Growth Factor Rev."},{"issue":"3","key":"10.1016\/j.fsi.2026.111274_bib28","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/BF00731324","article-title":"\u03b11-Acid glycoprotein (orosomucoid): pathophysiological changes in glycosylation in relation to its function","volume":"12","author":"Van Dijk","year":"1995","journal-title":"Glycoconj. J."},{"key":"10.1016\/j.fsi.2026.111274_bib29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.fsi.2020.04.015","article-title":"3nLcn2, a teleost lipocalin 2 that possesses antimicrobial activity and inhibits bacterial infection in triploid crucian carp","volume":"102","author":"Zhou","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111274_bib30","article-title":"Effects of saline-alkaline stress on metabolomics profiles, biochemical parameters, and liver histopathology in large yellow croaker (Larimichthys crocea)","volume":"52","author":"Zhou","year":"2024","journal-title":"Comp. Biochem. Physiol. Genom. Proteonomics"},{"key":"10.1016\/j.fsi.2026.111274_bib31","article-title":"Effects of low-salinity acclimation on the Na+\/K+ ATPase activity and expression of osmoregulatory-related genes in large yellow croaker (Larimichthys crocea)","volume":"26","author":"Han","year":"2022","journal-title":"Aquac. Rep."},{"issue":"2","key":"10.1016\/j.fsi.2026.111274_bib32","first-page":"204","article-title":"Salinity tolerance of Pseudosciaena crocea during early development","volume":"21","author":"L","year":"2012","journal-title":"J. Shanghai Ocean. Univer."},{"key":"10.1016\/j.fsi.2026.111274_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jac\/dkae380","article-title":"Bactericidal versus bacteriostatic antibacterials: clinical significance, differences and synergistic potential in clinical practice","volume":"80","author":"Ishak","year":"2025","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.fsi.2026.111274_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2023.108385","article-title":"Lipocalin family proteins and their diverse roles in cardiovascular disease","volume":"244","author":"Yang","year":"2023","journal-title":"Pharmacol. Ther."},{"issue":"2","key":"10.1016\/j.fsi.2026.111274_bib35","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.cyto.2011.07.021","article-title":"Lipocalin 2 regulation and its complex role in inflammation and cancer","volume":"56","author":"Li","year":"2011","journal-title":"Cytokine"},{"issue":"1","key":"10.1016\/j.fsi.2026.111274_bib36","article-title":"Lipocalin 2 inhibits the expressions of interleukin-8 and macrophage inflammatory protein-1\u03b1 in human neutrophil-like cells","volume":"67","author":"Kido","year":"2025","journal-title":"ournal of Oral Biosciences"},{"issue":"3","key":"10.1016\/j.fsi.2026.111274_bib37","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1053\/j.gastro.2006.05.051","article-title":"Effects of mouse and human lipocalin homologues 24p3\/lcn2 and neutrophil gelatinase-associated lipocalin on gastrointestinal mucosal integrity and repair","volume":"131","author":"Playford","year":"2006","journal-title":"Gastroenterology"},{"issue":"5","key":"10.1016\/j.fsi.2026.111274_bib38","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.3390\/antiox12051027","article-title":"Apolipoprotein D in oxidative stress and inflammation","volume":"12","author":"Fyfe-Desmarais","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.fsi.2026.111274_bib39","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.37172","article-title":"A bacterial immunomodulatory protein with lipocalin-like domains facilitates host-bacteria mutualism in larval zebrafish","volume":"7","author":"Rolig","year":"2018","journal-title":"eLife"},{"key":"10.1016\/j.fsi.2026.111274_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2020.103772","article-title":"Fish lysozyme gene family evolution and divergent function in early development","volume":"114","author":"Li","year":"2021","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2026.111274_bib41","doi-asserted-by":"crossref","DOI":"10.48130\/gcomm-0025-0020","article-title":"Evolutionary conservation of YTH domain-containing genes facilitating the functional achievement of m6A-modified RNAs under abiotic and biotic stresses in spotted sea bass (Lateolabrax maculatus)","volume":"2","author":"Zhu","year":"2025","journal-title":"Genomics Communications"},{"issue":"7","key":"10.1016\/j.fsi.2026.111274_bib42","first-page":"3919","article-title":"The antimicrobial peptides and their potential clinical applications","volume":"11","author":"Lei","year":"2019","journal-title":"Am. J. Transl. Res."},{"issue":"1-2","key":"10.1016\/j.fsi.2026.111274_bib43","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0005-2736(99)00201-1","article-title":"Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells","volume":"1462","author":"Dathe","year":"1999","journal-title":"Biochim. Biophys. Acta Biomembr."},{"issue":"6","key":"10.1016\/j.fsi.2026.111274_bib44","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1034\/j.1399-3011.2001.00934.x","article-title":"Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide P18 and its analogs","volume":"58","author":"Shin","year":"2001","journal-title":"J. Pept. Res."},{"issue":"16","key":"10.1016\/j.fsi.2026.111274_bib45","doi-asserted-by":"crossref","first-page":"3288","DOI":"10.1021\/bi101395j","article-title":"Structure-activity relationships of piscidin 4, a piscine antimicrobial peptide","volume":"50","author":"Park","year":"2011","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.fsi.2026.111274_bib46","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0086364","article-title":"Antimicrobial properties and membrane-active mechanism of a potential \u03b1-helical antimicrobial derived from cathelicidin PMAP-36","volume":"9","author":"Lv","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.fsi.2026.111274_bib47","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.peptides.2008.12.002","article-title":"A peptide fragment derived from the T-cell antigen receptor protein \u03b1-chain adopts \u03b2-sheet structure and shows potent antimicrobial activity","volume":"30","author":"Zhang","year":"2009","journal-title":"Peptides"},{"issue":"3 Suppl. 1","key":"10.1016\/j.fsi.2026.111274_bib48","doi-asserted-by":"crossref","first-page":"228a","DOI":"10.1016\/j.bpj.2016.11.1257","article-title":"The relationship of sequence and activity in a series of short \u03b2-sheet peptides with antimicrobial activity","volume":"112","author":"Kennelly","year":"2017","journal-title":"Biophys. J."},{"key":"10.1016\/j.fsi.2026.111274_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2019.103556","article-title":"Defensins: transcriptional regulation and function beyond antimicrobial activity","volume":"104","author":"Contreras","year":"2020","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2026.111274_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2021.114008","article-title":"Defensins: the natural peptide antibiotic","volume":"179","author":"Gao","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"8","key":"10.1016\/j.fsi.2026.111274_bib51","doi-asserted-by":"crossref","first-page":"4290","DOI":"10.3390\/ijms25084290","article-title":"Structure, functions, and implications of selected lipocalins in human disease","volume":"25","author":"Chandrasekaran","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.fsi.2026.111274_bib52","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1111\/jfb.14901","article-title":"Immune defence mechanisms presented in liver homogenates and bile of gilthead seabream (Sparus aurata)","volume":"99","author":"Gonz\u00e1lez-Silvera","year":"2021","journal-title":"J. Fish. Biol."},{"key":"10.1016\/j.fsi.2026.111274_bib53","article-title":"Comparative study on antibacterial characteristics of the multiple liver expressed antimicrobial peptides (LEAPs) in teleost fish","volume":"14","author":"Liu","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2026.111274_bib54","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00251-020-01196-0","article-title":"Anatomy of teleost fish immune structures and organs","volume":"73","author":"Bj\u00f8rgen","year":"2021","journal-title":"Immunogenetics"},{"key":"10.1016\/j.fsi.2026.111274_bib55","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.dci.2016.06.025","article-title":"The teleost head kidney: integrating thyroid and immune signalling","volume":"66","author":"Geven","year":"2017","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2026.111274_bib56","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.ygcen.2009.05.022","article-title":"Oogenesis in teleosts: how fish eggs are formed","volume":"165","author":"Lubzens","year":"2010","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.fsi.2026.111274_bib57","series-title":"The Fish Oocyte: from Basic Studies to Biotechnological Applications","first-page":"1","article-title":"Ultrastructural aspects of the ontogeny and differentiation of ray-finned fish ovarian follicles","author":"Menn","year":"2007"},{"key":"10.1016\/j.fsi.2026.111274_bib58","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1477-7827-6-2","article-title":"Identification of differentially expressed ovarian genes during primary and early secondary oocyte growth in coho salmon","volume":"6","author":"Luckenbach","year":"2008","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.fsi.2026.111274_bib59","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ygcen.2007.04.007","article-title":"Immune function varies with reproductive stage and context in female and male tree lizards","volume":"155","author":"French","year":"2008","journal-title":"Gen. Comp. Endocrinol."},{"issue":"8","key":"10.1016\/j.fsi.2026.111274_bib60","doi-asserted-by":"crossref","first-page":"587","DOI":"10.3390\/biology13080587","article-title":"Investigating development and defense systems in early reproductive stages of Male and female gonads in black ScorpionfishScorpaena porcus (Linnaeus, 1758)","volume":"13","author":"Alesci","year":"2024","journal-title":"Biology"},{"key":"10.1016\/j.fsi.2026.111274_bib61","doi-asserted-by":"crossref","DOI":"10.4194\/TRJFAS23922","article-title":"Antimicrobial peptides from fish: main forces for reducing and substituting antibiotics","volume":"24","author":"Wang","year":"2023","journal-title":"Turk. J. Fish. Aquat. Sci."},{"issue":"12","key":"10.1016\/j.fsi.2026.111274_bib62","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0012883","article-title":"Antibacterial and antiviral roles of a fish \u03b2-Defensin expressed both in pituitary and testis","volume":"5","author":"Jin","year":"2010","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.fsi.2026.111274_bib63","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0112918","article-title":"Poly(I:C) induces antiviral immune responses in Japanese flounder (Paralichthys olivaceus) that require TLR3 and MDA5 and are negatively regulated by Myd88","volume":"9","author":"Zhou","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.fsi.2026.111274_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2024.741676","article-title":"Effect of cortisol through GR regulated inflammatory cytokine expression and apoptosis of Siberian sturgeon (Acipenser baerii) after LPS treatment","volume":"595","author":"Tang","year":"2025","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2026.111274_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.109285","article-title":"Poly(I:C) induces anti-inflammatory response against secondary LPS challenge in zebrafish larvae","volume":"144","author":"Wang","year":"2024","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111274_bib66","article-title":"Spleen transcriptome profiling shows varying immune reactions to poly (I:C) and LPS challenge in the Ussuri catfish (Pseudobagrus ussuriensis)","volume":"44","author":"Liu","year":"2025","journal-title":"Aquac. Rep."},{"key":"10.1016\/j.fsi.2026.111274_bib67","doi-asserted-by":"crossref","unstructured":"J. Du, X. Xiang, D. Xu, et al., LPS stimulation induces small heterodimer partner expression through the AMPK-NRF2 pathway in large yellow croaker (Larimichthys crocea) Front. Immunol. 12, 753681, https:\/\/doi.org\/10.3389\/fimmu.2021.753681.","DOI":"10.3389\/fimmu.2021.753681"},{"key":"10.1016\/j.fsi.2026.111274_bib68","doi-asserted-by":"crossref","unstructured":"X. Yuan, Y. Rong, Y. Chen, et al., Molecular characterization, expression analysis and cellular location of IL-4\/13 receptors in large yellow croaker (Larimichthys crocea). Fish Shellfish Immunol. 120, 45-55, https:\/\/doi.org\/10.1016\/j.fsi.2021.11.007.","DOI":"10.1016\/j.fsi.2021.11.007"},{"issue":"6","key":"10.1016\/j.fsi.2026.111274_bib69","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/s41581-023-00692-2","article-title":"The role of lysosomes in metabolic and autoimmune diseases","volume":"19","author":"Gros","year":"2023","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.fsi.2026.111274_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.102824","article-title":"Lysosome impairment as a trigger for inflammation in obesity: the proof is in the fat","volume":"56","author":"Rawnsley","year":"2020","journal-title":"EBioMedicine"},{"issue":"2","key":"10.1016\/j.fsi.2026.111274_bib71","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.immuni.2011.06.009","article-title":"Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the arf-like GTPase Arl8b","volume":"35","author":"Garg","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.fsi.2026.111274_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.216728","article-title":"Pharmacological approaches for targeting lysosomes to induce ferroptotic cell death in cancer","volume":"587","author":"Feng","year":"2024","journal-title":"Cancer Lett."},{"key":"10.1016\/j.fsi.2026.111274_bib73","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.653828","article-title":"Endoplasmic reticulum-mitochondria contact sites -Emerging intracellular signaling hubs","volume":"9","author":"Aoyama-Ishiwatari","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"10","key":"10.1016\/j.fsi.2026.111274_bib74","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1038\/s41418-021-00859-z","article-title":"Organelle-specific regulation of ferroptosis","volume":"28","author":"Chen","year":"2021","journal-title":"Cell Death Differ."},{"issue":"6","key":"10.1016\/j.fsi.2026.111274_bib75","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.cell.2019.08.004","article-title":"TNF induces pathogenic programmed macrophage necrosis in tuberculosis through a mitochondrial-lysosomal-endoplasmic reticulum circuit","volume":"178","author":"Roca","year":"2019","journal-title":"Cell"},{"issue":"21","key":"10.1016\/j.fsi.2026.111274_bib76","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222111401","article-title":"Mechanism of antimicrobial peptides: antimicrobial, anti-inflammatory and antibiofilm activities","volume":"22","author":"Luo","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.fsi.2026.111274_bib77","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s40779-021-00343-2","article-title":"Antimicrobial peptides: mechanism of action, activity and clinical potential","volume":"8","author":"Zhang","year":"2021","journal-title":"Milit. Med. Res."},{"key":"10.1016\/j.fsi.2026.111274_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.addr.2021.114008","article-title":"Defensins: the natural peptide antibiotic","volume":"179","author":"Gao","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.fsi.2026.111274_bib79","doi-asserted-by":"crossref","first-page":"4877","DOI":"10.3390\/ijms20194877","article-title":"Non-lytic antibacterial peptides that translocate through bacterial membranes to act on intracellular targets","volume":"20","author":"Cardoso","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"8","key":"10.1016\/j.fsi.2026.111274_bib80","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1016\/j.bbamem.2013.03.023","article-title":"Mechanism of action of puroindoline-derived tryptophan-rich antimicrobial peptides","volume":"1828","author":"Haney","year":"2013","journal-title":"Biochim. Biophys. Acta, Biomembr."},{"issue":"11","key":"10.1016\/j.fsi.2026.111274_bib81","doi-asserted-by":"crossref","first-page":"2998","DOI":"10.1021\/bi00126a022","article-title":"Binding of tachyplesin I to DNA revealed by footprinting analysis: significant contribution of secondary structure to DNA binding and implication for biological action","volume":"31","author":"Yonezawa","year":"1992","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.fsi.2026.111274_bib82","doi-asserted-by":"crossref","first-page":"226","DOI":"10.4102\/sajid.v36i1.226","article-title":"Effect of antimicrobial peptides on planktonic growth, biofilm formation and biofilm-derived bacterial viability of Streptococcus pneumoniae","volume":"36","author":"Boswell","year":"2021","journal-title":"Southern African J. Infectious Diseases."},{"key":"10.1016\/j.fsi.2026.111274_bib83","doi-asserted-by":"crossref","first-page":"369a","DOI":"10.1016\/j.bpj.2022.11.2034","article-title":"Characterizing the role of the cell wall in bacterial death caused by treatment with antimicrobial peptides","volume":"122","author":"Lutz","year":"2023","journal-title":"Biophys. J."},{"key":"10.1016\/j.fsi.2026.111274_bib84","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.fsi.2022.03.020","article-title":"Antimicrobial and immunoregulatory activities of the derived peptide of a natural killer lysin from black rockfish (Sebastes schlegelii)","volume":"123","author":"Hao","year":"2022","journal-title":"Fish Shellfish Immunol."},{"issue":"16","key":"10.1016\/j.fsi.2026.111274_bib85","doi-asserted-by":"crossref","first-page":"4725","DOI":"10.1128\/JB.181.16.4725-4733.1999","article-title":"Structures of gram-negative cell walls and their derived membrane vesicles","volume":"181","author":"Beveridge","year":"1999","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.fsi.2026.111274_bib86","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/s41586-020-2236-6","article-title":"The architecture of the Gram-positive bacterial cell wall","volume":"582","author":"Lemonche","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.fsi.2026.111274_bib87","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3390\/ph9030059","article-title":"Antimicrobial peptides targeting gram-positive bacteria","volume":"9","author":"Malanovic","year":"2016","journal-title":"Pharmaceuticals"},{"issue":"5","key":"10.1016\/j.fsi.2026.111274_bib88","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.bbamem.2015.11.004","article-title":"Gram-positive bacterial cell envelopes: the impact on the activity of antimicrobial peptides","volume":"1858","author":"Malanovic","year":"2016","journal-title":"Biochim. Biophys. Acta"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464826001786?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464826001786?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T09:09:11Z","timestamp":1776157751000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464826001786"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":88,"alternative-id":["S1050464826001786"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2026.111274","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immunological functional studies of a putative lipocalin member LcApoM_AGPRP in large yellow croaker (Larimichthys crocea)","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2026.111274","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111274"}}