{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T02:17:15Z","timestamp":1783131435765,"version":"3.54.6"},"reference-count":123,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002924","name":"Federaci\u00f3n Espa\u00f1ola de Enfermedades Raras","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["MICIU\/AEI\/10.13039\/501100011033\/FEDER"],"award-info":[{"award-number":["MICIU\/AEI\/10.13039\/501100011033\/FEDER"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"State Agency of Research","doi-asserted-by":"publisher","award":["PID2023-148810OB-C21"],"award-info":[{"award-number":["PID2023-148810OB-C21"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011033","name":"State Agency of Research","doi-asserted-by":"publisher","award":["PRE2021-099386"],"award-info":[{"award-number":["PRE2021-099386"]}],"id":[{"id":"10.13039\/501100011033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund Plus","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["MCIN \/ AEI \/10.13039\/501100011033"],"award-info":[{"award-number":["MCIN \/ AEI \/10.13039\/501100011033"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.fsi.2026.111370","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T07:00:44Z","timestamp":1776754844000},"page":"111370","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Dissecting the host transcriptome and microbiota responses to viral hemorrhagic septicemia virus (VHSV) in the turbot (Scophthalmus maximus) intestine: insights from moribund and asymptomatic phenotypes"],"prefix":"10.1016","volume":"174","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8808-8912","authenticated-orcid":false,"given":"Nieves","family":"Mart\u00ednez-L\u00f3pez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0617-0030","authenticated-orcid":false,"given":"Antonio","family":"Figueras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Novoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8734-3334","authenticated-orcid":false,"given":"Patricia","family":"Pereiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fsi.2026.111370_bib1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0959-8030(95)00002-X","article-title":"Viral hemorrhagic septicemia virus in North America","volume":"5","author":"Meyers","year":"1995","journal-title":"Annu. Rev. Fish Dis."},{"key":"10.1016\/j.fsi.2026.111370_bib2","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3389\/fphys.2016.00192","article-title":"Turbot (Scophthalmus maximus) vs. VHSV (Viral hemorrhagic septicemia virus): a review","volume":"7","author":"Pereiro","year":"2016","journal-title":"Front. Physiol."},{"key":"10.1016\/j.fsi.2026.111370_bib3","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1111\/raq.12521","article-title":"Compilation of antiviral treatments and strategies to fight fish viruses","volume":"13","author":"Pereiro","year":"2021","journal-title":"Rev. Aquacult."},{"issue":"13","key":"10.1016\/j.fsi.2026.111370_bib4","doi-asserted-by":"crossref","first-page":"5672","DOI":"10.3390\/app14135672","article-title":"Advancements in fish vaccination: current innovations and future horizons in aquaculture health management","volume":"14","author":"Rathor","year":"2024","journal-title":"Appl. Sci."},{"key":"10.1016\/j.fsi.2026.111370_bib6","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.fsi.2014.10.038","article-title":"Difference in skin immune responses to infection with salmon louse (Lepeophtheirus salmonis) in Atlantic salmon (Salmo salar L.) of families selected for resistance and susceptibility","volume":"42","author":"Holm","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib7","doi-asserted-by":"crossref","first-page":"453","DOI":"10.3389\/fgene.2014.00453","article-title":"Whole-body transcriptome of selectively bred, resistant-, control-, and susceptible-line rainbow trout following experimental challenge with Flavobacterium psychrophilum","volume":"5","author":"Marancik","year":"2015","journal-title":"Front. Genet."},{"key":"10.1016\/j.fsi.2026.111370_bib8","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1186\/s12864-020-6694-x","article-title":"Characterising the mechanisms underlying genetic resistance to amoebic gill disease in Atlantic salmon using RNA sequencing","volume":"21","author":"Robledo","year":"2020","journal-title":"BMC Genom."},{"key":"10.1016\/j.fsi.2026.111370_bib9","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.fsi.2022.02.055","article-title":"Transcriptome analysis and protein-protein interaction in resistant and susceptible families of Japanese flounder (Paralichthys olivaceus) to understand the mechanism against Edwardsiella tarda","volume":"123","author":"Wang","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1522666","article-title":"Unravelling turbot (Scophthalmus maximus) resistance to Aeromonas salmonicida: transcriptomic insights from two full-sibling families with divergent susceptibility","volume":"15","author":"Pereiro","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib11","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s10126-012-9465-0","article-title":"Microarray-based identification of differentially expressed genes in families of turbot (Scophthalmus maximus) after infection with viral haemorrhagic septicaemia virus (VHSV)","volume":"14","author":"D\u00edaz-Rosales","year":"2012","journal-title":"Mar. Biotechnol."},{"issue":"2","key":"10.1016\/j.fsi.2026.111370_bib12","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.fsi.2015.04.037","article-title":"Liver functional metabolomics discloses an action of L-leucine against Streptococcus iniae infection in tilapias","volume":"45","author":"Ma","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib13","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.fsi.2022.08.065","article-title":"Taurine promotes Oreochromis niloticus survival against Edwardsiella tarda infection","volume":"129","author":"Peng","year":"2022","journal-title":"Fish Shellfish Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2026.111370_bib14","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/1751-7915.13553","article-title":"Metabolic modulation of redox state confounds fish survival against Vibrio alginolyticus infection","volume":"13","author":"Gong","year":"2020","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.fsi.2026.111370_bib15","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.fsi.2018.11.079","article-title":"Analysis of the gut and gill microbiome of resistant and susceptible lines of rainbow trout (Oncorhynchus mykiss)","volume":"86","author":"Brown","year":"2019","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib16","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/s40168-022-01346-4","article-title":"Intestinal microbiome-mediated resistance against vibriosis for Cynoglossus semilaevis","volume":"10","author":"Zhou","year":"2022","journal-title":"Microbiome"},{"key":"10.1016\/j.fsi.2026.111370_bib17","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/s41588-021-00983-z","article-title":"Challenges and future directions for studying effects of host genetics on the gut microbiome","volume":"54","author":"Sanna","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.fsi.2026.111370_bib18","article-title":"Gut microbiota, host genetics and phenotypes in aquatic animals: a review","volume":"31","author":"Gao","year":"2023","journal-title":"Aquac. Rep."},{"issue":"3","key":"10.1016\/j.fsi.2026.111370_bib19","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.celrep.2019.09.010","article-title":"Polymorphic immune mechanisms regulate commensal repertoire","volume":"29","author":"Khan","year":"2019","journal-title":"Cell Rep."},{"issue":"10","key":"10.1016\/j.fsi.2026.111370_bib20","doi-asserted-by":"crossref","first-page":"4003","DOI":"10.1128\/IAI.00037-15","article-title":"Intestinal microbiota of mice influences resistance to Staphylococcus aureus pneumonia","volume":"83","author":"Gauguet","year":"2015","journal-title":"Infect. Immun."},{"key":"10.1016\/j.fsi.2026.111370_bib21","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.593838","article-title":"Baseline gut microbiota composition is associated with Schistosoma mansoni infection burden in rodent models","volume":"11","author":"Cort\u00e9s","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib22","doi-asserted-by":"crossref","first-page":"2878","DOI":"10.3389\/fimmu.2019.02878","article-title":"Viral-infected change of the digestive tract microbiota associated with mucosal immunity in teleost fish","volume":"10","author":"Dong","year":"2019","journal-title":"Front. Immunol."},{"issue":"22","key":"10.1016\/j.fsi.2026.111370_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232214037","article-title":"Alterations of the mucosal immune response and microbial community of the skin upon viral infection in rainbow trout (Oncorhynchus mykiss)","volume":"23","author":"Zhan","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.fsi.2026.111370_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.109166","article-title":"Mucosal immunity and microbiota change in the rainbow trout (Oncorhynchus mykiss) gills after being challenged with infectious hematopoietic necrosis virus","volume":"142","author":"Tongsri","year":"2023","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib25","doi-asserted-by":"crossref","unstructured":"Xiao Joe JT, Tseng YC, Wu JL, Lu MW. The alteration of intestinal microbiota profile and immune response in Epinephelus coioides during pathogen infection. Life;11(2):99. https:\/\/doi.org\/10.3390\/life11020099.","DOI":"10.3390\/life11020099"},{"key":"10.1016\/j.fsi.2026.111370_bib26","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/are.15607","article-title":"Comparison of the gut microbiota composition between asymptomatic and diseased Epinephelus moara \u2640 \u00d7 Epinephelus lanceolatus \u2642 with nervous necrosis virus infection","volume":"53","author":"Wang","year":"2022","journal-title":"Aquac. Res."},{"key":"10.1016\/j.fsi.2026.111370_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2024.740752","article-title":"Tilapia lake virus infection disrupts the gut microbiota of red hybrid tilapia (Oreochromis spp.)","volume":"586","author":"Paimeeka","year":"2024","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2026.111370_bib28","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.654758","article-title":"Interactions between commensal microbiota and mucosal immunity in teleost fish during viral infection with SVCV","volume":"12","author":"Meng","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1100092","article-title":"An environmentally relevant concentration of antibiotics impairs the immune system of zebrafish (Danio rerio) and increases susceptibility to virus infection","volume":"13","author":"Pereiro","year":"2023","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib30","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/s40168-024-01958-y","article-title":"The intestinal microbiome and Cetobacterium somerae inhibit viral infection through TLR2-type I IFN signaling axis in zebrafish","volume":"12","author":"Liang","year":"2024","journal-title":"Microbiome"},{"key":"10.1016\/j.fsi.2026.111370_bib31","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.envpol.2017.12.073","article-title":"Environmental concentrations of antibiotics impair zebrafish gut health","volume":"235","author":"Zhou","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.fsi.2026.111370_bib32","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.immuni.2012.04.011","article-title":"Commensal bacteria calibrate the activation threshold of innate antiviral immunity","volume":"37","author":"Abt","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.fsi.2026.111370_bib33","doi-asserted-by":"crossref","first-page":"E762","DOI":"10.1073\/pnas.1518589113","article-title":"Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa","volume":"113","author":"Oh","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.fsi.2026.111370_bib34","doi-asserted-by":"crossref","first-page":"3768","DOI":"10.4049\/jimmunol.1502322","article-title":"Maternal antibiotic treatment impacts development of the neonatal intestinal microbiome and antiviral immunity","volume":"196","author":"Gonzalez-Perez","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib35","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.celrep.2019.05.105","article-title":"Microbiota-driven tonic interferon signals in lung stromal cells protect from influenza virus infection","volume":"28","author":"Bradley","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.fsi.2026.111370_bib36","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/oxfordjournals.aje.a118408","article-title":"A simple method of estimating fifty percent endpoints","volume":"27","author":"Reed","year":"1938","journal-title":"Am. J. Epidemiol."},{"issue":"3","key":"10.1016\/j.fsi.2026.111370_bib37","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1093\/dnares\/dsw007","article-title":"Whole genome sequencing of turbot (Scophthalmus maximus; Pleuronectiformes): a fish adapted to demersal life","volume":"23","author":"Figueras","year":"2016","journal-title":"DNA Res."},{"key":"10.1016\/j.fsi.2026.111370_bib38","doi-asserted-by":"crossref","first-page":"W566","DOI":"10.1093\/nar\/gkv468","article-title":"ClustVis: a web tool for visualizing clustering of multivariate data using principal component analysis and heatmap","volume":"43","author":"Metsalu","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.fsi.2026.111370_bib39","doi-asserted-by":"crossref","first-page":"D605","DOI":"10.1093\/nar\/gkaa1074","article-title":"The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene\/measurement sets","volume":"49","author":"Szklarczyk","year":"2021","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.fsi.2026.111370_bib40","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: an R package for comparing biological themes among gene clusters","volume":"16","author":"Yu","year":"2012","journal-title":"OMICS A J. Integr. Biol."},{"key":"10.1016\/j.fsi.2026.111370_bib41","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/pro.3711","article-title":"KEGG mapper for inferring cellular functions from protein sequences","volume":"29","author":"Kanehisa","year":"2020","journal-title":"Protein Sci."},{"key":"10.1016\/j.fsi.2026.111370_bib42","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.fsi.2026.111370_bib43","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gks808","article-title":"Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies","volume":"41","author":"Klindworth","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.fsi.2026.111370_bib44","author":"Oksanen"},{"key":"10.1016\/j.fsi.2026.111370_bib45","series-title":"ggplot2: Elegant Graphics for Data Analysis","author":"Wickham","year":"2016"},{"key":"10.1016\/j.fsi.2026.111370_bib46","doi-asserted-by":"crossref","first-page":"585","DOI":"10.3389\/fmicb.2019.00585","article-title":"A new method to correct for habitat filtering in microbial correlation networks","volume":"10","author":"Brisson","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.fsi.2026.111370_bib47","author":"Kassambara"},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib48","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1609\/icwsm.v3i1.13937","article-title":"Gephi: an open source software for exploring and manipulating networks","volume":"3","author":"Bastian","year":"2009","journal-title":"Proc Int AAAI Conf Weblogs Soc Media."},{"issue":"P02001","key":"10.1016\/j.fsi.2026.111370_bib49","article-title":"Cartography of complex networks: modules and universal roles","volume":"2005","author":"Guimer\u00e0","year":"2005","journal-title":"J Stat Mech."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib50","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s40793-020-00358-7","article-title":"Tax4Fun2: prediction of habitat-specific functional profiles and functional redundancy based on 16S rRNA gene sequences","volume":"15","author":"Wemheuer","year":"2020","journal-title":"Environ Microbiome"},{"key":"10.1016\/j.fsi.2026.111370_bib51","article-title":"pheatmap: Pretty Heatmaps (R package version 1.0.13)","author":"Kolde","year":"2025","journal-title":"Comput. Software"},{"issue":"2","key":"10.1016\/j.fsi.2026.111370_bib52","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3354\/dao047087","article-title":"An outbreak of VHSV (viral hemorrhagic septicemia virus) infection in farmed Japanese flounder Paralichthys olivaceus in Japan","volume":"47","author":"Isshik","year":"2001","journal-title":"Dis. Aquat. Org."},{"issue":"5","key":"10.1016\/j.fsi.2026.111370_bib53","doi-asserted-by":"crossref","first-page":"734","DOI":"10.3390\/v4050734","article-title":"Spread of the emerging viral hemorrhagic septicemia virus strain, genotype IVb, in Michigan, USA","volume":"4","author":"Faisal","year":"2012","journal-title":"Viruses"},{"key":"10.1016\/j.fsi.2026.111370_bib54","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/j.fsi.2013.09.032","article-title":"The mucosal immune system of fish: the evolution of tolerating commensals while fighting pathogens","volume":"35","author":"Gomez","year":"2013","journal-title":"Fish Shellfish Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2026.111370_bib55","doi-asserted-by":"crossref","first-page":"525","DOI":"10.3390\/biology4030525","article-title":"The mucosal immune system of teleost fish","volume":"4","author":"Salinas","year":"2015","journal-title":"Biology"},{"key":"10.1016\/j.fsi.2026.111370_bib56","article-title":"Recent insights and advances in gut microbiota's influence on host antiviral immunity","volume":"16","author":"Liu","year":"2025","journal-title":"Front. Microbiol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib57","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.cell.2014.03.011","article-title":"Role of the microbiota in immunity and inflammation","volume":"157","author":"Belkaid","year":"2014","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib58","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s00253-023-12934-1","article-title":"The interactions between the host immunity and intestinal microorganisms in fish","volume":"108","author":"Zhang","year":"2024","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib59","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/nri3345","article-title":"Thrombosis as an intravascular effector of innate immunity","volume":"13","author":"Engelmann","year":"2013","journal-title":"Nat. Rev. Immunol."},{"issue":"16","key":"10.1016\/j.fsi.2026.111370_bib60","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241612563","article-title":"The crossroads of the coagulation system and the immune system: interactions and connections","volume":"24","author":"Wilhelm","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"8","key":"10.1016\/j.fsi.2026.111370_bib61","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S1473-3099(04)01103-X","article-title":"Pathogenesis of filoviral haemorrhagic fevers","volume":"4","author":"Mahanty","year":"2004","journal-title":"Lancet Infect. Dis."},{"issue":"4","key":"10.1016\/j.fsi.2026.111370_bib62","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1128\/CMR.00035-09","article-title":"Dengue virus pathogenesis: an integrated view","volume":"22","author":"Martina","year":"2009","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.fsi.2026.111370_bib63","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3354\/dao020101","article-title":"Comparison of immunohistochemistry and virus cultivation for detection of viral haemorrhagic septicaemia virus in experimentally infected rainbow trout Oncorhynchus mykiss","volume":"20","author":"Evensen","year":"1994","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.fsi.2026.111370_bib64","doi-asserted-by":"crossref","first-page":"6335","DOI":"10.3390\/ijms20246335","article-title":"Inducible nitric oxide synthase (iNOS) mediates vascular endothelial cell apoptosis in grass carp reovirus (GCRV)-induced hemorrhage","volume":"20","author":"Liang","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.fsi.2026.111370_bib65","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1016\/j.immuni.2021.10.012","article-title":"The immunology of sepsis","volume":"54","author":"van der Poll","year":"2021","journal-title":"Immunity"},{"issue":"3","key":"10.1016\/j.fsi.2026.111370_bib66","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.cmet.2016.08.013","article-title":"Food fight: role of iitaconate and other metabolites in antimicrobial defense","volume":"24","author":"Luan","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.fsi.2026.111370_bib67","article-title":"The role of PD-1 signaling in health and immune-related diseases","volume":"14","author":"Chen","year":"2023","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib68","doi-asserted-by":"crossref","first-page":"6267","DOI":"10.1038\/s41467-025-61346-4","article-title":"Mrc1 (MMR, CD206) controls the blood proteome in reducing inflammation, age-associated organ dysfunction and mortality in sepsis","volume":"16","author":"Restagno","year":"2025","journal-title":"Nat. Commun."},{"issue":"9","key":"10.1016\/j.fsi.2026.111370_bib69","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/nri.2016.70","article-title":"A guide to immunometabolism for immunologists","volume":"16","author":"O'Neill","year":"2016","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2024.741525","article-title":"Exploring common modulations induced by three fish RNA viruses in turbot (Scophthalmus maximus): Cholesterol, vitamin D3 and retinol metabolism as shared targets","volume":"595","author":"Pereiro","year":"2025","journal-title":"Aquaculture"},{"issue":"6","key":"10.1016\/j.fsi.2026.111370_bib71","doi-asserted-by":"crossref","first-page":"908","DOI":"10.3390\/v16060908","article-title":"Significance of cellular lipid metabolism for the replication of rotaviruses and other RNA viruses","volume":"16","author":"Desselberger","year":"2024","journal-title":"Viruses"},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib72","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.abb.2011.11.003","article-title":"25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D","volume":"523","author":"Jones","year":"2012","journal-title":"Arch. Biochem. Biophys."},{"issue":"4","key":"10.1016\/j.fsi.2026.111370_bib73","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3748\/wjg.v24.i4.445","article-title":"Vitamin D deficiency and hepatitis viruses-associated liver diseases: a literature review","volume":"24","author":"Hoan","year":"2018","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.fsi.2026.111370_bib74","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2025.130292","article-title":"Potential of fat-soluble vitamins as a platform for antiviral drug development","volume":"127","author":"Hirota","year":"2025","journal-title":"Bioorg. Med. Chem. Lett"},{"issue":"6","key":"10.1016\/j.fsi.2026.111370_bib75","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/01.WCB.0000073905.87928.6D","article-title":"Heme and iron metabolism: role in cerebral hemorrhage","volume":"23","author":"Wagner","year":"2003","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.fsi.2026.111370_bib76","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.3389\/fmicb.2017.01809","article-title":"Dietary heme induces gut dysbiosis, aggravates colitis, and potentiates the development of adenomas in mice","volume":"8","author":"Constante","year":"2017","journal-title":"Front. Microbiol."},{"issue":"4","key":"10.1016\/j.fsi.2026.111370_bib77","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.cell.2023.12.036","article-title":"Gut complement induced by the microbiota combats pathogens and spares commensals","volume":"187","author":"Wu","year":"2024","journal-title":"Cell"},{"issue":"19","key":"10.1016\/j.fsi.2026.111370_bib78","doi-asserted-by":"crossref","DOI":"10.1172\/JCI188349","article-title":"Gut complement system: a new frontier in microbiota-host communication and intestinal homeostasis","volume":"135","author":"Tian","year":"2025","journal-title":"J. Clin. Investig."},{"issue":"2","key":"10.1016\/j.fsi.2026.111370_bib79","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.chom.2010.07.005","article-title":"Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma","volume":"8","author":"Saha","year":"2010","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.fsi.2026.111370_bib80","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.3389\/fimmu.2019.01551","article-title":"The commensal microbiota and viral infection: a comprehensive review","volume":"10","author":"Li","year":"2019","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.fsi.2026.111370_bib81","doi-asserted-by":"crossref","first-page":"950","DOI":"10.3390\/v14050950","article-title":"Role of microbiota in viral infections and pathological progression","volume":"14","author":"Mizutani","year":"2022","journal-title":"Viruses"},{"issue":"3","key":"10.1016\/j.fsi.2026.111370_bib82","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.chom.2013.08.006","article-title":"Alterations in the gut microbiota associated with HIV-1 infection","volume":"14","author":"Lozupone","year":"2013","journal-title":"Cell Host Microbe"},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib83","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12916-021-02212-0","article-title":"Gut microbiome alterations and gut barrier dysfunction are associated with host immune homeostasis in COVID-19 patients","volume":"20","author":"Sun","year":"2022","journal-title":"BMC Med."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib84","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.bpg.2015.12.002","article-title":"Probiotics and prebiotics in infectious gastroenteritis","volume":"30","author":"Vandenplas","year":"2016","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"key":"10.1016\/j.fsi.2026.111370_bib85","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3389\/fcimb.2019.00377","article-title":"Hepatitis B virus infection alters gut microbiota composition in mice","volume":"9","author":"Zhu","year":"2019","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.fsi.2026.111370_bib86","doi-asserted-by":"crossref","DOI":"10.1038\/srep16865","article-title":"Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity","volume":"5","author":"Mitra","year":"2015","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.fsi.2026.111370_bib87","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3390\/fishes8060294","article-title":"Changes in the gut microbiota composition of juvenile olive flounder (Paralichthys olivaceus) caused by pathogenic bacterial infection","volume":"8","author":"Kim","year":"2023","journal-title":"Fishes"},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib88","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-66112-y","article-title":"The impact of tetrodotoxin (TTX) on the gut microbiome in juvenile tiger pufferfish, Takifugu rubripes","volume":"14","author":"Wassel","year":"2024","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.fsi.2026.111370_bib89","doi-asserted-by":"crossref","first-page":"964","DOI":"10.3390\/microorganisms9050964","article-title":"Alteration of the immune response and the microbiota of the skin during a natural infection by Vibrio harveyi in European seabass (Dicentrarchus labrax)","volume":"9","author":"C\u00e1mara-Ruiz","year":"2021","journal-title":"Microorganisms"},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib90","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-81822-z","article-title":"Analyzing bacterial networks and interactions in skin and gills of Sparus aurata with microalgae-based additive feeding","volume":"14","author":"Cerezo","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fsi.2026.111370_bib91","article-title":"Pathology and pathogenesis of vibrio infection in fish: a review","volume":"28","author":"Manchanayake","year":"2023","journal-title":"Aquac. Rep."},{"key":"10.1016\/j.fsi.2026.111370_bib92","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1188876","article-title":"Sole microbiome progression in a hatchery like cycle, from egg to juvenile","volume":"14","author":"Almeida","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.fsi.2026.111370_bib93","article-title":"Identification of taurine as a resistance-associated metabolite against Aeromonas salmonicida and its protective, immune-regulatory, and microbiota-shaping effects in turbot (Scophthalmus maximus)","volume":"592","author":"Pereiro","year":"2025","journal-title":"Aquaculture"},{"key":"10.1016\/j.fsi.2026.111370_bib94","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.838640","article-title":"Microbiome of Penaeus vannamei larvae and potential biomarkers associated with high and low survival in shrimp hatchery tanks affected by acute hepatopancreatic necrosis disease","volume":"13","author":"Reyes","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.fsi.2026.111370_bib95","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3844\/ajbbsp.2016.36.46","article-title":"Antimicrobial and antioxidant activities of bacterial extracts from marine bacteria associated with sponge Stylotella sp","volume":"12","author":"Yoghiapiscessa","year":"2016","journal-title":"Am. J. Biochem. Biotechnol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib96","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s40168-020-00835-8","article-title":"Metabarcoding reveals distinct microbiotypes in the giant clam Tridacna maxima","volume":"8","author":"Guibert","year":"2020","journal-title":"Microbiome"},{"key":"10.1016\/j.fsi.2026.111370_bib97","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.109616","article-title":"Exploring the underlying mechanisms of enteritis impact on golden pompano (Trachinotus ovatus) through multi-omics analysis","volume":"150","author":"Yuan","year":"2024","journal-title":"Fish Shellfish Immunol."},{"issue":"4","key":"10.1016\/j.fsi.2026.111370_bib98","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1128\/CMR.00017-11","article-title":"Serratia infections: from military experiments to current practice","volume":"24","author":"Mahlen","year":"2011","journal-title":"Clin. Microbiol. Rev."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib99","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12915-019-0699-4","article-title":"The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health","volume":"17","author":"Waters","year":"2019","journal-title":"BMC Biol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2021.1880221","article-title":"Elevated gut microbiome abundance of Christensenellaceae, Porphyromonadaceae and Rikenellaceae is associated with reduced visceral adipose tissue and healthier metabolic profile in Italian elderly","volume":"13","author":"Tavella","year":"2021","journal-title":"Gut Microbes"},{"key":"10.1016\/j.fsi.2026.111370_bib101","article-title":"Bacterial community composition and function in different habitats in Antarctic Fildes region revealed by high-throughput sequencing","volume":"16","author":"Zhang","year":"2025","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.fsi.2026.111370_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108562","article-title":"Effects of Cryptocaryon irritans infection on the histopathology, oxidative stress, immune response, and intestinal microbiota in the orange-spotted grouper Epinephelus coioides","volume":"133","author":"Zeng","year":"2023","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111370_bib103","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2025.110596","article-title":"Ginsenoside Re exerts neuroprotective in MPTP mice: potential links to gut microbiota and serum metabolism","volume":"282","author":"Li","year":"2026","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.fsi.2026.111370_bib104","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.4652","article-title":"Accuracy of taxonomy prediction for 16S rRNA and fungal ITS sequences","volume":"6","author":"Edgar","year":"2018","journal-title":"PeerJ"},{"key":"10.1016\/j.fsi.2026.111370_bib105","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.3389\/fmicb.2019.02083","article-title":"Analysis of 1,000 type-strain genomes improves taxonomic classification of bacteroidetes","volume":"10","author":"Garc\u00eda-L\u00f3pez","year":"2019","journal-title":"Front. Microbiol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib106","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s40168-023-01697-6","article-title":"Host species and habitat shape fish-associated bacterial communities: phylosymbiosis between fish and their microbiome","volume":"11","author":"Sadeghi","year":"2023","journal-title":"Microbiome"},{"key":"10.1016\/j.fsi.2026.111370_bib107","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1016\/j.csbj.2023.03.050","article-title":"Analysis of microbiota-host communication mediated by butyrate in Atlantic salmon","volume":"21","author":"Vargas","year":"2023","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"10.1016\/j.fsi.2026.111370_bib108","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2020.1824563","article-title":"Conserved anti-inflammatory effects and sensing of butyrate in zebrafish","volume":"12","author":"Cholan","year":"2020","journal-title":"Gut Microbes"},{"issue":"Pt 6","key":"10.1016\/j.fsi.2026.111370_bib109","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1099\/ijs.0.000199","article-title":"Aestuariicella hydrocarbonica gen. nov., sp. nov., an aliphatic hydrocarbon-degrading bacterium isolated from a sea tidal flat","volume":"65","author":"Lo","year":"2015","journal-title":"Int. J. Syst. Evol. Microbiol."},{"issue":"8","key":"10.1016\/j.fsi.2026.111370_bib110","doi-asserted-by":"crossref","DOI":"10.1099\/ijsem.0.005493","article-title":"Aestuariicella albida sp. nov., isolated from surface water of the Yellow sea, and proposal of the genus Aestuariicella as a member of the family Cellvibrionaceae","volume":"72","author":"Xue","year":"2022","journal-title":"Int. J. Syst. Evol. Microbiol."},{"issue":"8","key":"10.1016\/j.fsi.2026.111370_bib111","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3390\/microorganisms8081189","article-title":"Bacteriomic profiling of branchial lesions induced by Neoparamoeba perurans challenge reveals commensal dysbiosis and an association with Tenacibaculum dicentrarchi in AGD-affected Atlantic salmon (Salmo salar L.)","volume":"8","author":"Slinger","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.fsi.2026.111370_bib112","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143558","article-title":"Polystyrene microplastics alter the intestinal microbiota function and the hepatic metabolism status in marine medaka (Oryzias melastigma)","volume":"759","author":"Feng","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib113","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/s43705-023-00243-7","article-title":"Mediterranean Sea heatwaves jeopardize greater amberjack's (Seriola dumerili) aquaculture productivity through impacts on the fish microbiota","volume":"3","author":"S\u00e1nchez-Cueto","year":"2023","journal-title":"ISME Commun."},{"key":"10.1016\/j.fsi.2026.111370_bib114","doi-asserted-by":"crossref","DOI":"10.3389\/faquc.2023.1270932","article-title":"Bacterial community structures and dynamics associated with rotated positioning syndrome in gilthead sea bream (Sparus aurata) larviculture","volume":"2","author":"Bel Mokhtar","year":"2024","journal-title":"Front Aquac"},{"key":"10.1016\/j.fsi.2026.111370_bib115","doi-asserted-by":"crossref","DOI":"10.1016\/j.micres.2025.128317","article-title":"Akkermansia muciniphila: a key player in gut microbiota-based disease modulation","volume":"301","author":"Shaheen","year":"2025","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.fsi.2026.111370_bib116","doi-asserted-by":"crossref","DOI":"10.1111\/cmi.13348","article-title":"Short chain fatty acids released by Fusobacterium nucleatum are neutrophil chemoattractants acting via free fatty acid receptor 2 (FFAR2)","volume":"23","author":"Dahlstrand Rudin","year":"2021","journal-title":"Cell. Microbiol."},{"issue":"9","key":"10.1016\/j.fsi.2026.111370_bib117","doi-asserted-by":"crossref","first-page":"796","DOI":"10.3390\/pathogens13090796","article-title":"Metabolic footprint of Treponema phagedenis and Treponema pedis reveals potential interaction towards community succession and pathogenesis in bovine digital dermatitis","volume":"13","author":"Espiritu","year":"2024","journal-title":"Pathogens"},{"issue":"11","key":"10.1016\/j.fsi.2026.111370_bib118","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1016\/j.tjnut.2025.08.034","article-title":"Microbiota-dependent fiber responses: a proof-of-concept study on short-chain fatty acid production in Prevotella- and Bacteroides-dominated healthy individuals","volume":"155","author":"Bartsch","year":"2025","journal-title":"J. Nutr."},{"key":"10.1016\/j.fsi.2026.111370_bib119","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2025.110699","article-title":"Gut-protective effects of dietary niacin in juvenile turbot (Scophthalmus maximus L.) fed a high-lipid diet: modulation of mucosal immune response, barrier function, and gut microbiota","volume":"167","author":"Ge","year":"2025","journal-title":"Fish Shellfish Immunol."},{"issue":"1","key":"10.1016\/j.fsi.2026.111370_bib120","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/mi.2014.44","article-title":"Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway","volume":"8","author":"Park","year":"2015","journal-title":"Mucosal Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2026.111370_bib121","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.cmet.2024.01.014","article-title":"Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin \u03b12\u03b21","volume":"36","author":"Huang","year":"2024","journal-title":"Cell Metab."},{"issue":"7","key":"10.1016\/j.fsi.2026.111370_bib122","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1056\/NEJMra0910283","article-title":"Hypoxia and inflammation","volume":"364","author":"Eltzschig","year":"2011","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.fsi.2026.111370_bib123","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.chom.2015.03.005","article-title":"Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function","volume":"17","author":"Kelly","year":"2015","journal-title":"Cell Host Microbe"},{"issue":"6418","key":"10.1016\/j.fsi.2026.111370_bib124","doi-asserted-by":"crossref","DOI":"10.1126\/science.aat9076","article-title":"Colonocyte metabolism shapes the gut microbiota","volume":"362","author":"Litvak","year":"2018","journal-title":"Science"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464826002743?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464826002743?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T01:29:08Z","timestamp":1783128548000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464826002743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":123,"alternative-id":["S1050464826002743"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2026.111370","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dissecting the host transcriptome and microbiota responses to viral hemorrhagic septicemia virus (VHSV) in the turbot (Scophthalmus maximus) intestine: insights from moribund and asymptomatic phenotypes","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2026.111370","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"111370"}}