{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:43:53Z","timestamp":1786121033775,"version":"build-2736575974"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.fsi.2026.111612","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T23:25:34Z","timestamp":1785194734000},"page":"111612","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A teleost NK-lysin derived peptide inhibits SVCV infection by disruption viral adhesion\/entry and activating type I interferon response"],"prefix":"10.1016","volume":"177","author":[{"given":"Zi-Yue","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Shu","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-Hua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuo","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.fsi.2026.111612_bib1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.3354\/dao052261","article-title":"Spring viremia of carp (SVC)","volume":"52","author":"Ahne","year":"2002","journal-title":"Dis. Aquat. Org."},{"issue":"6","key":"10.1016\/j.fsi.2026.111612_bib2","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1051\/vetres\/2010022","article-title":"Emerging viral diseases of fish and shrimp","volume":"41","author":"Walker","year":"2010","journal-title":"Vet. Res."},{"issue":"5","key":"10.1016\/j.fsi.2026.111612_bib3","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1099\/jgv.0.000436","article-title":"Spring viraemia of carp virus: recent advances","volume":"97","author":"Ashraf","year":"2016","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.fsi.2026.111612_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.109726","article-title":"Histopathology and transcriptome profiling reveal features of immune responses in gills and intestine induced by spring viremia of carp virus","volume":"152","author":"Ouyang","year":"2024","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib5","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/j.fsi.2018.12.063","article-title":"SVCV infection triggers fish IFN response through RLR signaling pathway","volume":"86","author":"Gong","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2023.106293","article-title":"Infection of epithelioma papulosum cyprini (EPC) cells with spring viremia of carp virus (SVCV) induces autophagy and apoptosis through endoplasmic reticulum stress","volume":"183","author":"Jiao","year":"2023","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.fsi.2026.111612_bib7","series-title":"The State of World Fisheries and Aquaculture 2022: towards Blue Transformation","year":"2022"},{"issue":"2","key":"10.1016\/j.fsi.2026.111612_bib8","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/S0006-3495(02)75226-0","article-title":"Membrane composition determines pardaxin's mechanism of lipid bilayer disruption","volume":"83","author":"Hallock","year":"2002","journal-title":"Biophys. J."},{"issue":"12","key":"10.1016\/j.fsi.2026.111612_bib9","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.3390\/ph6121543","article-title":"Antimicrobial peptides","volume":"6","author":"Bahar","year":"2013","journal-title":"Pharmaceuticals"},{"issue":"2","key":"10.1016\/j.fsi.2026.111612_bib10","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.fsi.2010.11.021","article-title":"Molecular cloning and characterization of two novel hepcidins from orange-spotted grouper, Epinephelus coioides","volume":"30","author":"Zhou","year":"2011","journal-title":"Fish Shellfish Immunol."},{"issue":"3","key":"10.1016\/j.fsi.2026.111612_bib11","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/0014-5793(95)00268-E","article-title":"An amphipathic helical motif common to tumourolytic polypeptide NK-lysin and pulmonary surfactant polypeptide SP-B","volume":"362","author":"Andersson","year":"1995","journal-title":"FEBS Lett."},{"issue":"8","key":"10.1016\/j.fsi.2026.111612_bib12","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1002\/j.1460-2075.1995.tb07150.x","article-title":"NK-lysin, a novel effector peptide of cytotoxic T and NK cells. Structure and cDNA cloning of the porcine form, induction by interleukin 2, antibacterial and antitumour activity","volume":"14","author":"Andersson","year":"1995","journal-title":"EMBO J."},{"issue":"1\u20134","key":"10.1016\/j.fsi.2026.111612_bib13","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0165-2427(96)05677-2","article-title":"NK-lysin, structure and function of a novel effector molecule of porcine T and NK cells","volume":"54","author":"Andersson","year":"1996","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"2","key":"10.1016\/j.fsi.2026.111612_bib14","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3390\/md17020087","article-title":"Antiviral activity of a turbot (Scophthalmus maximus) NK-Lysin peptide by inhibition of low-pH virus-induced membrane fusion","volume":"7","author":"Falco","year":"2019","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.fsi.2026.111612_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2021.105104","article-title":"NK-lysin peptides ameliorate viral encephalopathy and retinopathy disease signs and provide partial protection against nodavirus infection in European sea bass","volume":"192","author":"Valero","year":"2021","journal-title":"Antivir. Res."},{"key":"10.1016\/j.fsi.2026.111612_bib16","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.fsi.2021.12.050","article-title":"Investigation of putative antimicrobial peptides in Carassius gibel, revealing a practical approach to screening antimicrobials","volume":"121","author":"Zhang","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.109749","article-title":"Characterization of Myxovirus resistance (Mx) gene from Chinese seabass Lateolabrax maculatus: insights into the evolution and function of Mx genes","volume":"152","author":"Ming","year":"2024","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.109129","article-title":"In-vitro immunomodulatory responses and antiviral activities of antimicrobial peptide octominin against fish pathogenic viruses","volume":"142","author":"Dias","year":"2023","journal-title":"Fish Shellfish Immunol."},{"issue":"7","key":"10.1016\/j.fsi.2026.111612_bib20","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1021\/es60130a004","article-title":"Trimmed Spearman-karber method for estimating median lethal concentrations in toxicity bioassays","volume":"11","author":"Hamilton","year":"1977","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fsi.2026.111612_bib21","first-page":"556","article-title":"Characterization of a megalocytivirus from cultured rock bream, Oplegnathus fasciatus (Temminck & Schlege), in China, Aquac","volume":"43","author":"Zhang","year":"2012","journal-title":"Res."},{"key":"10.1016\/j.fsi.2026.111612_bib17","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3354\/dao03863","article-title":"Identification of antibacterial and chemotactic activities of a novel NK-lysin peptide from Lateolabrax japonicus, Dis","volume":"163","author":"Wang","year":"2025","journal-title":"Aquat. Organ."},{"issue":"5","key":"10.1016\/j.fsi.2026.111612_bib22","first-page":"559","article-title":"An experimental research on different detection conditions between MTT and CCK-8","volume":"16","author":"Xiong","year":"2007","journal-title":"Acta Laser Biol. Sinica."},{"key":"10.1016\/j.fsi.2026.111612_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2025.105374","article-title":"Mx of Sebastes schlegelii: expression pattern, antibacterial activity and antiviral mechanism","volume":"167","author":"Zhang","year":"2025","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2025.110357","article-title":"Characterization and functional analysis of integrin \u03b1V in Sebastes schlegelii: implications for apoptosis, adhesion, and migration in intestinal cells","volume":"162","author":"Ma","year":"2025","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.109553","article-title":"Tissue factor pathway inhibitors disrupt structures of rhabdovirus\/ranairidovirus and inhibit viral infection in Chinese perch, Siniperca chuatsi","volume":"149","author":"Ma","year":"2024","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.145037","article-title":"Immunometabolic interplay and molecular characterization of hepcidins reveal ferroptosis mechanisms to Edwardsiella piscicida infection in black rockfish Sebastes schlegeli","volume":"318","author":"Jing","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.fsi.2026.111612_bib29","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1191966","article-title":"New insight into the biological activity of Salmo salar NK-lysin antimicrobial peptides","volume":"15","author":"Ortega","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.109099","article-title":"Antibacterial and anticancer activity of two NK-lysin-derived peptides from the antarctic teleost Trematomus bernacchii","volume":"142","author":"Buonocore","year":"2023","journal-title":"Fish Shellfish Immunol."},{"issue":"4","key":"10.1016\/j.fsi.2026.111612_bib31","doi-asserted-by":"crossref","first-page":"511","DOI":"10.3390\/biom10040511","article-title":"Octominin inhibits LPS-induced chemokine and pro-inflammatory cytokine secretion from RAW 264.7 macrophages via blocking TLRs\/NF-\u03baB signal transduction","volume":"10","author":"Sanjeewa","year":"2020","journal-title":"Biomolecules"},{"issue":"8","key":"10.1016\/j.fsi.2026.111612_bib32","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1016\/j.burns.2024.07.036","article-title":"Promising anti-inflammatory activity of a novel designed anti-microbial peptide for wound healing","volume":"50","author":"Fathi","year":"2024","journal-title":"Burns"},{"issue":"1","key":"10.1016\/j.fsi.2026.111612_bib33","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1600-0757.2010.00373.x","article-title":"Epithelial cell-derived antimicrobial peptides are multifunctional agents that bridge innate and adaptive immunity","volume":"54","author":"McCormick","year":"2010","journal-title":"Periodontol. 2000"},{"key":"10.1016\/j.fsi.2026.111612_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.127590","article-title":"Anti-microbial activity and immunomodulation of recombinant hepcidin 2 and NK-lysin from flounder (Paralichthys olivaceus)","volume":"253","author":"Li","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.fsi.2026.111612_bib35","doi-asserted-by":"crossref","first-page":"722","DOI":"10.3389\/fimmu.2018.00722","article-title":"Cathelicidin-derived antimicrobial peptides inhibit zika virus through direct inactivation and interferon pathway","volume":"9","author":"He","year":"2018","journal-title":"Front. Immunol."},{"issue":"12","key":"10.1016\/j.fsi.2026.111612_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0012883","article-title":"Antibacterial and antiviral roles of a fish \u03b2-defensin expressed both in pituitary and testis","volume":"5","author":"Jin","year":"2010","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.fsi.2026.111612_bib37","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s12985-019-1199-4","article-title":"Antiviral activity of Piscidin 1 against pseudorabies virus both in vitro and in vivo","volume":"16","author":"Hu","year":"2019","journal-title":"Virol. J."},{"issue":"6","key":"10.1016\/j.fsi.2026.111612_bib38","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.peptides.2010.02.025","article-title":"Antiviral activity by fish antimicrobial peptides of epinecidin-1 and hepcidin 1-5 against nervous necrosis virus in medaka","volume":"31","author":"Wang","year":"2010","journal-title":"Peptides"},{"key":"10.1016\/j.fsi.2026.111612_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2024.105855","article-title":"Construction of exosome-loaded LL-37 and its protection against zika virus infection","volume":"225","author":"Wang","year":"2024","journal-title":"Antivir. Res."},{"key":"10.1016\/j.fsi.2026.111612_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2025.110467","article-title":"Epigallocatechin gallate (EGCG) inhibits Micropterus salmoides rhabdovirus replication via suppressing viral attachment and infectivity","volume":"165","author":"Wang","year":"2025","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2024.740592","article-title":"Hepcidin and dicentracin peptides show preventive antiviral applications against NNV infection in European sea bass through immunomodulatory roles","volume":"583","author":"Cervera","year":"2024","journal-title":"Aquaculture"},{"issue":"3","key":"10.1016\/j.fsi.2026.111612_bib42","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1167\/tvst.3.3.4","article-title":"Cathelicidin LL-37 and HSV-1 corneal infection: peptide Versus gene therapy","volume":"3","author":"Lee","year":"2014","journal-title":"Transl. Vis. Sci. Technol."},{"issue":"6","key":"10.1016\/j.fsi.2026.111612_bib43","doi-asserted-by":"crossref","first-page":"573","DOI":"10.3851\/IMP2918","article-title":"Inhibitory activity and molecular mechanism of protegrin-1 against porcine reproductive and respiratory syndrome virus in vitro","volume":"20","author":"Guo","year":"2015","journal-title":"Antivir. Ther."},{"issue":"8","key":"10.1016\/j.fsi.2026.111612_bib44","article-title":"Synthetic host defense peptide inhibits SARS-CoV-2 replication in vitro, antimicrob. Agents","volume":"69","author":"Harfoot","year":"2025","journal-title":"Chemother."},{"issue":"1","key":"10.1016\/j.fsi.2026.111612_bib45","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.01859-24","article-title":"Platelet factor 4-derived C15 peptide broadly inhibits enteroviruses by disrupting viral attachment","volume":"99","author":"Lv","year":"2025","journal-title":"J. Virol."},{"issue":"29","key":"10.1016\/j.fsi.2026.111612_bib46","article-title":"Morphological transformations of SARS-CoV-2 nucleocapsid protein biocondensates mediated by antimicrobial peptides","volume":"30","author":"Campanile","year":"2024","journal-title":"Chemistry"},{"key":"10.1016\/j.fsi.2026.111612_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.virol.2025.110456","article-title":"Origin and function of anti-interferon type I viral proteins","volume":"605","author":"Acchioni","year":"2025","journal-title":"Virology"},{"key":"10.1016\/j.fsi.2026.111612_bib48","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.peptides.2018.07.003","article-title":"Grouper (Epinephelus coioides) antimicrobial peptide epinecidin-1 exhibits antiviral activity against foot-and-mouth disease virus in vitro","volume":"106","author":"Huang","year":"2018","journal-title":"Peptides"},{"key":"10.1016\/j.fsi.2026.111612_bib49","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.fsi.2022.06.053","article-title":"Fish TRIM21 exhibits antiviral activity against grouper iridovirus and nodavirus infection","volume":"127","author":"Zheng","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.985291","article-title":"Grouper TRIM23 exerts antiviral activity against iridovirus and nodavirus","volume":"13","author":"Zhi","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib51","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1191966","article-title":"New insight into the biological activity of Salmo salar NK-lysin antimicrobial peptides","volume":"15","author":"Ortega","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.peptides.2024.171320","article-title":"Host defense peptides at the crossroad of endothelial cell physiology: insight into mechanistic and pharmacological implications","volume":"182","author":"Garg","year":"2024","journal-title":"Peptides"},{"issue":"3\u20134","key":"10.1016\/j.fsi.2026.111612_bib53","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.dci.2013.03.005","article-title":"A NK-lysin from Cynoglossus semilaevis enhances antimicrobial defense against bacterial and viral pathogens","volume":"40","author":"Zhang","year":"2013","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.fsi.2026.111612_bib54","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.fsi.2022.03.020","article-title":"Antimicrobial and immunoregulatory activities of the derived peptide of a natural killer lysin from black rockfish (Sebastes schlegelii)","volume":"123","author":"Hao","year":"2022","journal-title":"Fish Shellfish Immunol."}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464826005164?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464826005164?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T02:20:17Z","timestamp":1786069217000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464826005164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":52,"alternative-id":["S1050464826005164"],"URL":"https:\/\/doi.org\/10.1016\/j.fsi.2026.111612","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A teleost NK-lysin derived peptide inhibits SVCV infection by disruption viral adhesion\/entry and activating type I interferon response","name":"articletitle","label":"Article Title"},{"value":"Fish & Shellfish Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fsi.2026.111612","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111612"}}