{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T08:24:08Z","timestamp":1793262248901,"version":"4.5.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T00:00:00Z","timestamp":1740268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009192","name":"Alberta Innovates","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009192","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gait & Posture"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.gaitpost.2025.02.006","type":"journal-article","created":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T16:53:37Z","timestamp":1740588817000},"page":"118-126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["The effect of sarcopenic obesity on knee biomechanics in individuals with end-stage knee osteoarthritis"],"prefix":"10.1016","volume":"119","author":[{"given":"Ahmed","family":"Negm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert H.","family":"Vette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allyson","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Beaupre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gaitpost.2025.02.006_bib1","unstructured":"Public Health Agency of Canada P. Life with arthritis in Canada: a personal and public health challenge. Public Health Agency of Canada. \u3008http:\/\/www.phac-aspc.gc.ca\/cd-mc\/arthritis-arthrite\/lwaic-vaaac-10\/pdf\/arthritis-2010-eng.pdf\u3009."},{"issue":"7","key":"10.1016\/j.gaitpost.2025.02.006_bib2","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1136\/annrheumdis-2013-204763","article-title":"The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study","volume":"73","author":"Cross","year":"2014","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.gaitpost.2025.02.006_bib3","unstructured":"CIHI. Hip and Knee Replacements in Canada: Canadian Joint Replacement Registry 2014 Annual Report. 2014. Accessed May 4th 2016 \u3008https:\/\/www.cihi.ca\/en\/quick-stats\u3009."},{"issue":"3","key":"10.1016\/j.gaitpost.2025.02.006_bib4","first-page":"454","article-title":"The effect of age on pain, function, and quality of life after total hip and knee arthroplasty","volume":"161","author":"Jones","year":"2001","journal-title":"Res. Support, Non-U. S. Gov. 't. Arch. Intern Med."},{"key":"10.1016\/j.gaitpost.2025.02.006_bib5","unstructured":"Global Burden of Disease Collaborative Network. Global Burden of Disease Study 2019 (GBD 2019) results. Accessed June 1, 2023, 2023. \u3008https:\/\/vizhub.healthdata.org\/gbd-results\/\u3009."},{"issue":"5","key":"10.1016\/j.gaitpost.2025.02.006_bib6","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/sj.ijo.0801585","article-title":"Knee osteoarthritis and obesity","volume":"25","author":"Coggon","year":"2001","journal-title":"Int J. Obes. Relat. Metab. Disord."},{"issue":"8","key":"10.1016\/j.gaitpost.2025.02.006_bib7","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/sj.ijo.0803287","article-title":"Separate and combined influence of body mass index and waist circumference on arthritis and knee osteoarthritis","volume":"30","author":"Janssen","year":"2006","journal-title":"Int J. Obes. (Lond. )"},{"issue":"2","key":"10.1016\/j.gaitpost.2025.02.006_bib8","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jcjd.2013.02.059","article-title":"The public health burden of obesity in Canada","volume":"37","author":"Janssen","year":"2013","journal-title":"Can. J. Diabetes"},{"issue":"11","key":"10.1016\/j.gaitpost.2025.02.006_bib9","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1007\/s00167-011-1403-6","article-title":"Unload it: the key to the treatment of knee osteoarthritis","volume":"19","author":"Waller","year":"2011","journal-title":"Knee Surg. Sports Trauma. Arthrosc."},{"issue":"3","key":"10.1016\/j.gaitpost.2025.02.006_bib10","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1023\/B:ABME.0000017541.82498.37","article-title":"A framework for the in vivo pathomechanics of osteoarthritis at the knee","volume":"32","author":"Andriacchi","year":"2004","journal-title":"Ann. Biomed. Eng."},{"issue":"3","key":"10.1016\/j.gaitpost.2025.02.006_bib11","doi-asserted-by":"crossref","DOI":"10.4155\/fsoa-2016-0028","article-title":"Physical activity and sarcopenic obesity: definition, assessment, prevalence and mechanism","volume":"2","author":"Lee","year":"2016","journal-title":"Future Sci. OA"},{"issue":"6","key":"10.1016\/j.gaitpost.2025.02.006_bib12","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jamda.2011.04.014","article-title":"Sarcopenia with limited mobility: an international consensus","volume":"12","author":"Morley","year":"2011","journal-title":"J. Am. Med Dir. Assoc."},{"issue":"4","key":"10.1016\/j.gaitpost.2025.02.006_bib13","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"},{"issue":"4","key":"10.1016\/j.gaitpost.2025.02.006_bib14","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jamda.2011.01.003","article-title":"Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia","volume":"12","author":"Fielding","year":"2011","journal-title":"J. Am. Med Dir. Assoc."},{"key":"10.1016\/j.gaitpost.2025.02.006_bib15","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3389\/fnagi.2014.00192","article-title":"Sarcopenia and physical frailty: two sides of the same coin","volume":"6","author":"Cesari","year":"2014","journal-title":"Front Aging Neurosci."},{"issue":"3","key":"10.1016\/j.gaitpost.2025.02.006_bib16","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1093\/gerona\/60.3.324","article-title":"Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons","volume":"60","author":"Visser","year":"2005","journal-title":"J. Gerontol. A Biol. Sci. Med Sci."},{"issue":"3","key":"10.1016\/j.gaitpost.2025.02.006_bib17","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.jocd.2010.04.002","article-title":"Jumping mechanography: a potential tool for sarcopenia evaluation in older individuals","volume":"13","author":"Buehring","year":"2010","journal-title":"J. Clin. Densitom."},{"issue":"1","key":"10.1016\/j.gaitpost.2025.02.006_bib18","doi-asserted-by":"crossref","first-page":"i44","DOI":"10.1093\/fampra\/cmr063","article-title":"Sarcopenia in the elderly","volume":"29","author":"Morley","year":"2012","journal-title":"Fam. Pr."},{"issue":"5","key":"10.1016\/j.gaitpost.2025.02.006_bib19","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1097\/BOR.0b013e32833b4682","article-title":"The evolving role of obesity in knee osteoarthritis","volume":"22","author":"Sowers","year":"2010","journal-title":"Curr. Opin. Rheuma"},{"key":"10.1016\/j.gaitpost.2025.02.006_bib20","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","author":"Cruz-Jentoft","year":"2018","journal-title":"Age Ageing"},{"issue":"5","key":"10.1016\/j.gaitpost.2025.02.006_bib21","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1093\/gerona\/glu010","article-title":"The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates","volume":"69","author":"Studenski","year":"2014","journal-title":"J. Gerontol. A Biol. Sci. Med Sci."},{"issue":"3","key":"10.1016\/j.gaitpost.2025.02.006_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0174663","article-title":"Six degree-of-freedom knee joint kinematics in obese individuals with knee pain during gait","volume":"12","author":"Li","year":"2017","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.gaitpost.2025.02.006_bib23","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.clinbiomech.2008.02.004","article-title":"Three-dimensional gait analysis of obese adults","volume":"23","author":"Lai","year":"2008","journal-title":"Clin. Biomech. (Bristol, Avon)"},{"issue":"12","key":"10.1016\/j.gaitpost.2025.02.006_bib24","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1111\/j.1467-789X.2011.00916.x","article-title":"A systematic review on changed biomechanics of lower extremities in obese individuals: a possible role in development of osteoarthritis","volume":"12","author":"Runhaar","year":"2011","journal-title":"Obes. Rev."},{"issue":"4","key":"10.1016\/j.gaitpost.2025.02.006_bib25","first-page":"471","article-title":"The effects of weight and activity on select kinematic gait variables in adult females","volume":"13","author":"Glave","year":"2013","journal-title":"J. Phys. Educ. Sport"},{"issue":"6","key":"10.1016\/j.gaitpost.2025.02.006_bib26","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1249\/MSS.0000000000000218","article-title":"Effects of an obesity-specific marker set on estimated muscle and joint forces in walking","volume":"46","author":"Lerner","year":"2014","journal-title":"Med Sci. Sports Exerc"},{"issue":"12","key":"10.1016\/j.gaitpost.2025.02.006_bib27","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1016\/j.jbiomech.2012.05.039","article-title":"Effects of perturbation magnitude on dynamic stability when walking in destabilizing environments","volume":"45","author":"Sinitksi","year":"2012","journal-title":"J. Biomech."},{"issue":"2","key":"10.1016\/j.gaitpost.2025.02.006_bib28","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.arth.2010.03.021","article-title":"The effect of total knee arthroplasty on knee joint kinematics and kinetics during gait","volume":"26","author":"Hatfield","year":"2011","journal-title":"J. Arthroplast."},{"key":"10.1016\/j.gaitpost.2025.02.006_bib29","author":"Hawker","year":"2011","journal-title":"Arthritis Care Res."},{"issue":"5","key":"10.1016\/j.gaitpost.2025.02.006_bib30","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1093\/occmed\/kqx063","article-title":"The Borg Rating of Perceived Exertion (RPE) scale","volume":"67","author":"Williams","year":"2017","journal-title":"Occup. Med."},{"key":"10.1016\/j.gaitpost.2025.02.006_bib31","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1477-7525-1-17","article-title":"Knee injury and Osteoarthritis Outcome Score (KOOS) - validation and comparison to the WOMAC in total knee replacement","volume":"1","author":"Roos","year":"2003","journal-title":"Health Qual. Life Outcomes"},{"issue":"2","key":"10.1016\/j.gaitpost.2025.02.006_bib32","doi-asserted-by":"crossref","first-page":"88","DOI":"10.2519\/jospt.1998.28.2.88","article-title":"Knee Injury and Osteoarthritis Outcome Score (KOOS)--development of a self-administered outcome measure","volume":"28","author":"Roos","year":"1998","journal-title":"J. Orthop. Sports Phys. Ther."},{"issue":"12","key":"10.1016\/j.gaitpost.2025.02.006_bib33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0189190","article-title":"Group B-B-SSM. The EQ-5D-5L is a valid approach to measure health related quality of life in patients undergoing bariatric surgery","volume":"12","author":"Fermont","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.gaitpost.2025.02.006_bib34","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.knee.2023.06.004","article-title":"Knee injury and osteoarthritis outcome score (KOOS) - National record-based reference values","volume":"43","author":"Larsen","year":"2023","journal-title":"Knee"},{"key":"10.1016\/j.gaitpost.2025.02.006_bib35","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/1477-7525-11-110","article-title":"Validity and responsiveness of EuroQol-5 dimension (EQ-5D) versus Short Form-6 dimension (SF-6D) questionnaire in chronic pain","volume":"11","author":"Obradovic","year":"2013","journal-title":"Health Qual. Life Outcomes"},{"key":"10.1016\/j.gaitpost.2025.02.006_bib36","doi-asserted-by":"crossref","unstructured":"Robertson D., Caldwell G., Hamill J., Kamen G., Whittlesey S. Research Methods in Biomechanics: Second edition (eBook), 2013.","DOI":"10.5040\/9781492595809"},{"key":"10.1016\/j.gaitpost.2025.02.006_bib37","series-title":"Introduction to Robotics","author":"Craig","year":"2006"},{"issue":"4","key":"10.1016\/j.gaitpost.2025.02.006_bib38","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.gaitpost.2013.02.010","article-title":"Center of pressure trajectories, trunk kinematics and trunk muscle activation during unstable sitting in low back pain patients","volume":"38","author":"Willigenburg","year":"2013","journal-title":"Gait Posture"},{"key":"10.1016\/j.gaitpost.2025.02.006_bib39","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.clinbiomech.2017.08.013","article-title":"The influence of sex and obesity on gait biomechanics in people with severe knee osteoarthritis scheduled for arthroplasty","volume":"49","author":"Paterson","year":"2017","journal-title":"Clin. Biomech. (Bristol, Avon)"},{"issue":"3","key":"10.1016\/j.gaitpost.2025.02.006_bib40","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.gaitpost.2013.01.001","article-title":"Reliability of principal components and discrete parameters of knee angle and moment gait waveforms in individuals with moderate knee osteoarthritis","volume":"38","author":"Robbins","year":"2013","journal-title":"Gait Posture"},{"issue":"4","key":"10.1016\/j.gaitpost.2025.02.006_bib41","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"}],"container-title":["Gait & Posture"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966636225000967?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966636225000967?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T11:55:54Z","timestamp":1746100554000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0966636225000967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":41,"alternative-id":["S0966636225000967"],"URL":"https:\/\/doi.org\/10.1016\/j.gaitpost.2025.02.006","relation":{},"ISSN":["0966-6362"],"issn-type":[{"value":"0966-6362","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of sarcopenic obesity on knee biomechanics in individuals with end-stage knee osteoarthritis","name":"articletitle","label":"Article Title"},{"value":"Gait & Posture","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gaitpost.2025.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}