{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T04:51:01Z","timestamp":1648875061448},"reference-count":16,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterolog\u00eda y Hepatolog\u00eda"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.gastrohep.2015.10.005","type":"journal-article","created":{"date-parts":[[2015,11,22]],"date-time":"2015-11-22T05:48:42Z","timestamp":1448171322000},"page":"377-384","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive variables of sustained virological response after early discontinuation of triple therapy with telaprevir for genotype-1 HCV infection"],"prefix":"10.1016","volume":"39","author":[{"given":"Doroteo","family":"Acero Fern\u00e1ndez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Morillas Cunill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Ferri Iglesias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Torras Collell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mercedes","family":"Vergara G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natividad","family":"Zaragoza Velasco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"L\u00f3pez Nu\u00f1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Montserrat","family":"Forn\u00e9 Bardera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mercedes","family":"Delgado G\u00f3mez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merc\u00e8","family":"Barenys Lacha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miquel","family":"Torres Salinas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarita","family":"Villar Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Dur\u00e1ndez L\u00e1zaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoe","family":"Mari\u00f1o Mendez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gastrohep.2015.10.005_bib0085","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.gastrohep.2012.03.005","article-title":"Documento de posicionamiento de la Societat Catalana de Digestologia: tratamiento tripIle de la hepatitis cr\u00f3nica C genotipo 1","volume":"35","author":"Bruguera","year":"2012","journal-title":"Gastroenterol Hepatol"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0090","series-title":"Criterios y recomendaciones generales para el tratamiento con Boceprevir y telaprevir de la hepatitis cr\u00f3nica C (VHC) en pacientes monoinfectados. Informe de utilidad terap\u00e9utica. UT\/V1\/2802","author":"Agencia Espa\u00f1ola de Medicamentos y Productos Sanitarios","year":"2012"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0095","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1056\/NEJMoa0806104","article-title":"Telaprevir and perginterferon and ribavirin for chronic HCV genotype 1 infection","volume":"360","author":"McHutchinson","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0100","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1056\/NEJMoa0807650","article-title":"Telaprevir and peginterferon with or without ribavirin for chronic HCV infection","volume":"360","author":"H\u00e9zode","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0105","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1056\/NEJMoa0908014","article-title":"Telaprevir for previously treated chronic HCV infection","volume":"362","author":"McHutchinson","year":"2010","journal-title":"N Eng J Med"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0110","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1056\/NEJMoa1012912","article-title":"Telaprevir for previously untreated chronic hepatitis C virus infection","volume":"364","author":"Jacobson","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0115","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1056\/NEJMoa1013086","article-title":"Telaprevir for retreatment of HCV infection","volume":"364","author":"Zeuzem","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0120","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1056\/NEJMoa1014463","article-title":"Response-guided telaprevir combination treatment for hepatitis C virus infection","volume":"365","author":"Sherman","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0125","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0140-6736(10)60934-8","article-title":"Efficacy of Boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-na\u00efve patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial","volume":"376","author":"Kwo","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0130","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1056\/NEJMoa1010494","article-title":"Boceprevir for untreated chronic HCV genotype 1 infection","volume":"364","author":"Poordad","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0135","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1056\/NEJMoa1009482","article-title":"Boceprevir for previously treated chronic HCV genotype 1 infection","volume":"364","author":"Bacon","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0140","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.gastrohep.2014.04.003","article-title":"La finalizaci\u00f3n precoz del tratamiento triple con telaprevir de la hepatitis cr\u00f3nica C por efecto adverso grave no presupone necesariamente el fracaso del tratamiento","volume":"38","author":"Virol\u00e9s","year":"2015","journal-title":"Gastroenterol Hepatol"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0145","first-page":"375A","article-title":"Predictors of virologic response with telaprevir-based combination treatment in HCV genotype 1-infected patients with prior peg-inf\/ribavirin failure: post-hoc analysis of the phase III REALIZE study","volume":"54","author":"Berg","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0150","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.gastrohep.2014.04.004","article-title":"Valor de la gen\u00e9tica en la era de la terapia triple frente al virus de la hepatitis C","volume":"37","author":"Quiles","year":"2014","journal-title":"Gastroenterol Hepatol"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0155","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1002\/hep.23509","article-title":"Systemic and intrahepatic interferon-gamma-inducible protein 10-kDa predicts first phase decline in hepatitis C virus RNA and overall response to therapy in chronic hepatitis C","volume":"51","author":"Askarieh","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.gastrohep.2015.10.005_bib0160","doi-asserted-by":"crossref","first-page":"e17232","DOI":"10.1371\/journal.pone.0017232","article-title":"Response prediction in chronic hepatitis C by assessment of PI-10 and IL28B-related single nucleotide polymorphisms","volume":"6","author":"Lagging","year":"2011","journal-title":"PLoS ONE"}],"container-title":["Gastroenterolog\u00eda y Hepatolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0210570515002484?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0210570515002484?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T14:26:43Z","timestamp":1537194403000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0210570515002484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["S0210570515002484"],"URL":"https:\/\/doi.org\/10.1016\/j.gastrohep.2015.10.005","relation":{},"ISSN":["0210-5705"],"issn-type":[{"value":"0210-5705","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictive variables of sustained virological response after early discontinuation of triple therapy with telaprevir for genotype-1 HCV infection","name":"articletitle","label":"Article Title"},{"value":"Gastroenterolog\u00eda y Hepatolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gastrohep.2015.10.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2015 Elsevier Espa\u00f1a, S.L.U., AEEH y AEG. All rights reserved.","name":"copyright","label":"Copyright"}]}}