{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T12:39:22Z","timestamp":1759667962288},"reference-count":88,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterolog\u00eda y Hepatolog\u00eda"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.gastrohep.2016.03.001","type":"journal-article","created":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T12:43:26Z","timestamp":1462106606000},"page":"99-106","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Gu\u00eda pr\u00e1ctica para el examen del paciente adulto con hipertransaminasemia asintom\u00e1tica"],"prefix":"10.1016","volume":"40","author":[{"given":"Miguel","family":"Bruguera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gastrohep.2016.03.001_bib0445","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1007\/BF01299887","article-title":"Serum alanine aminotransferase (ALT) elevation in asymptomatic US Air Force basic trainee blood donors","volume":"38","author":"Kundrotas","year":"1993","journal-title":"Dig Dis Sci."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0450","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1111\/j.1572-0241.2005.00341.x","article-title":"The prevalence and predictors of elevated serum aminotransferase activity in the United States in 1999-2002","volume":"101","author":"Ioannu","year":"2006","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0455","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1023\/A:1022809430756","article-title":"Prevalence of transaminase abnormalities in asymptomatic, healthy subjects participating in an executive health-screening program","volume":"48","author":"Patt","year":"2003","journal-title":"Dig Dis Sci."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0460","doi-asserted-by":"crossref","first-page":"536","DOI":"10.3122\/jabfm.2012.04.110183","article-title":"Consider muscle disease in children with elevated transaminase","volume":"25","author":"Wright","year":"2012","journal-title":"J Am Board Fam Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0465","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1111\/j.1440-1754.2010.01730.x","article-title":"Aminotransferases and muscular diseases: A disregarded lesson. Case reports and review of the literature","volume":"48","author":"Veropalumbo","year":"2012","journal-title":"Paediatr Child Health."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0470","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/hep.20548","article-title":"Serum alanine aminotransferase in skeletal muscle disease","volume":"41","author":"Nathwani","year":"2005","journal-title":"Hepatology."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0475","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1365-2036.2011.04895.x","article-title":"Hypertransaminasemia and coeliac disease","volume":"35","author":"Vajro","year":"2012","journal-title":"Aliment Pharmacol Ther."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0480","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1038\/ajg.2011.134","article-title":"Gluten-sensitive hypertransaminasemia in celiac disease: An infrequent and often subclinical finding","volume":"106","author":"Korpim\u00e4ki","year":"2011","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0485","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1157\/13108825","article-title":"Hipertransaminasemia en la enfermedad celiaca del adulto","volume":"30","author":"Huguet","year":"2007","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0490","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/S0002-9270(99)00076-3","article-title":"Persistent hypertransaminasemia as the presenting feature of celiac disease","volume":"94","author":"Gonz\u00e1lez-Abraldes","year":"1999","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0495","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3122\/jabfm.2008.06.080047","article-title":"The relationship of hepatitis antibodies and elevated liver enzymes with impaired fasting glucose and undiagnosed diabetes","volume":"21","author":"Mainous","year":"2008","journal-title":"J Am Board Fam Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0500","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1097\/00000478-200604000-00012","article-title":"Glycogenic hepatopathy: An underrecognized hepatic complication of diabetes mellitus","volume":"30","author":"Torbenson","year":"2006","journal-title":"Am J Surg Pathol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0505","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1111\/imj.12807","article-title":"Glycogenic hepatopathy is an under-recognised cause of hepatomegaly and elevated liver transaminases in type 1 diabetes mellitus","volume":"45","author":"Irani","year":"2015","journal-title":"Intern Med J."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0510","first-page":"1","article-title":"Hepatic dysfunction in hospitalized patients with acute thyrotoxicosis: A decade of experience","author":"Elias","year":"2012","journal-title":"Endocrinology."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0515","first-page":"435","article-title":"Liver involvement in Addison's disease","volume":"85","author":"Olsson","year":"1990","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0520","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1007\/s10620-008-0297-8","article-title":"Addison's disease: A rare cause of hypertransaminasaemia","volume":"53","author":"Ersan","year":"2008","journal-title":"Dig Dis Sci."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0525","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/0016-5085(95)90595-2","article-title":"Subclinical Addison's disease: A cause of persistent abnormalities in transaminase values","volume":"109","author":"Boulton","year":"1995","journal-title":"Gastroenterology."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0530","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1097\/00042737-199810000-00014","article-title":"Hypertransaminasemia and Addison's disease","volume":"10","author":"Castiella","year":"1998","journal-title":"Eur J Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0535","doi-asserted-by":"crossref","first-page":"3396","DOI":"10.1007\/s10620-007-9743-2","article-title":"Rotavirus causes hepatic transaminase elevation","volume":"52","author":"Teitelbaum","year":"2007","journal-title":"Dig Dis Sci."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0540","doi-asserted-by":"crossref","first-page":"160","DOI":"10.4103\/2249-4863.104992","article-title":"Salmonella hepatitis: An uncommon complication of a common disease","volume":"1","author":"Karoli","year":"2012","journal-title":"J Family Med Prim Care."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0545","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1157\/13089695","article-title":"Hepatitis due to herpes group viruses","volume":"24","author":"Cisneros-Herreros","year":"2006","journal-title":"Enferm Infecc Microbiol Clin."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0550","doi-asserted-by":"crossref","first-page":"5651","DOI":"10.3748\/wjg.v16.i45.5651","article-title":"Non-steroidal anti-inflammatory drugs: What is the actual risk of liver damage?","volume":"16","author":"Bessone","year":"2010","journal-title":"World J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0555","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1055\/s-0034-1375956","article-title":"Drug-induced liver injury due to antimicrobials, central nervous system agents, and nonsteroidal anti-inflammatory drugs","volume":"34","author":"Devarbhavi","year":"2014","journal-title":"Semin Liver Dis."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0560","first-page":"1105","article-title":"Mildly elevated liver transaminase levels in the asymptomatic patient","volume":"71","author":"Giboney","year":"2005","journal-title":"Am Fam Physician."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0565","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1157\/13099265","article-title":"Hepatitis aguda asociada a la toma de Copalchi. A prop\u00f3sito de 5 casos","volume":"30","author":"Bruguera","year":"2007","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0570","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1001\/jama.296.1.87","article-title":"Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: A randomized controlled trial","volume":"296","author":"Watkins","year":"2006","journal-title":"JAMA."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0575","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1592\/phco.30.8.818","article-title":"Serum alanine aminotransferase elevation during 10 days of acetaminophen use in nondrinkers","volume":"30","author":"Heard","year":"2010","journal-title":"Pharmacotherapy."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0580","doi-asserted-by":"crossref","first-page":"399","DOI":"10.7326\/0003-4819-104-3-399","article-title":"Acetaminophen hepatotoxicity in alcoholics. A therapeutic misadventure","volume":"104","author":"Seeff","year":"1986","journal-title":"Ann Intern Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0585","first-page":"235","article-title":"Severe hepatitis from therapeutic doses of paracetamol in an alcoholic patient","volume":"22","author":"Andreu","year":"1999","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0590","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1185\/030079906X148346","article-title":"Retrospective analysis of transient elevations in alanine aminotransferase during long-term treatment with acetaminophen in osteoarthritis clinical trials","volume":"22","author":"Kuffner","year":"2006","journal-title":"Curr Med Res Opin."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0595","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1365-2125.2007.03001.x","article-title":"Muscular exercise can cause highly pathological liver function tests in healthy men","volume":"65","author":"Pettersson","year":"2008","journal-title":"Br J Clin Pharmacol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0600","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.gastrohep.2014.03.017","article-title":"Hipertransaminasemia moderada en un paciente asimptomatico despu\u00e9s de ejercicio f\u00edsico en un gimnasio","volume":"37","author":"Tulewicz","year":"2014","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0605","first-page":"391","article-title":"Evaluation of aminotransferase elevations in a bodybuilder using anabolic steroids: Hepatitis or rhabdomyolysis?","volume":"101","author":"Pertusi","year":"2001","journal-title":"J Am Osteopath Assoc."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0610","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1053\/j.gastro.2008.02.077","article-title":"Diagnosis and therapy of nonalcoholic steatohepatitis","volume":"134","author":"Torres","year":"2008","journal-title":"Gastroenterology."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0615","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/MEG.0b013e32832fcdf0","article-title":"Prevalence and factors associated with the presence of nonalcoholic fatty liver disease in an adult population in Spain","volume":"22","author":"Caballer\u00eda","year":"2010","journal-title":"Eur J Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0620","first-page":"11","article-title":"Patients with coeliac disease are increasingly overweight or obese on presentation","volume":"21","author":"Tucker","year":"2012","journal-title":"J Gastrointestin Liver Dis."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0625","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jhep.2015.01.034","article-title":"Hepatic steatosis in Wilson disease \u2014 role of copper and PNPLA3 mutations","volume":"63","author":"St\u00e4ttermayer","year":"2015","journal-title":"J Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0630","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1111\/j.1572-0241.2004.30444.x","article-title":"The prevalence of autoantibodies and autoimmune hepatitis in patients with nonalcoholic fatty liver disease","volume":"99","author":"Adams","year":"2004","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0635","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.clnu.2012.08.020","article-title":"Hypertransaminasemia in severe malnourished adult anorexia nervosa patients: Risk factors and evolution under enteral nutrition","volume":"32","author":"Hanachi","year":"2013","journal-title":"Clin Nutr."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0640","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jcv.2014.12.017","article-title":"HEV infection in two referral centers in Spain: Epidemiology and clinical outcomes","volume":"63","author":"Lens","year":"2015","journal-title":"J Clin Virol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0645","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jinf.2009.02.013","article-title":"Prevalence of occult hepatitis B virus infection among hepatopathy patients and healthy people in China","volume":"58","author":"Fang","year":"2009","journal-title":"J Infect."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0650","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0973-6883(11)60130-8","article-title":"Occult hepatitis C virus infection and its relevance in clinical practice","volume":"1","author":"Pham","year":"2011","journal-title":"J Clin Exp Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0655","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/00005176-199211000-00018","article-title":"Immunoglobulin complexed AST (\u2018macro-AST\u2019) in an asymptomatic child with persistent hypertransaminasemia","volume":"15","author":"Vajro","year":"1992","journal-title":"J Pediatr Gastroenterol Nutr."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0660","first-page":"549","article-title":"Macroaspartate aminotransferase. Study of 5 cases and review of the literature","volume":"22","author":"Goenner","year":"1998","journal-title":"Gastroenterol Clin Biol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0665","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1007\/BF01324898","article-title":"The SGOT\/SGPT ratio \u2014 an indicator of alcoholic liver disease","volume":"24","author":"Cohen","year":"1979","journal-title":"Dig Dis Sci."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0670","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S0140-6736(71)90093-6","article-title":"Plasma gamma-glutamyl transpeptidase elevation in patients receiving enzyme-inducing drugs","volume":"2","author":"Rosalki","year":"1971","journal-title":"Lancet."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0675","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S0016-5085(88)80022-2","article-title":"Ratio of serum aspartate to alanine aminotrasferase in chronic hepatitis","volume":"95","author":"Williams","year":"1988","journal-title":"Gastroenterology."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0680","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1097\/00004836-199806000-00016","article-title":"Abnormal liver tests results in myotonic dystrophy","volume":"26","author":"Achiron","year":"1998","journal-title":"J Clin Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0685","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S1665-2681(19)31497-8","article-title":"Abnormal liver function tests in a patient with myotonic dystrophy type 1","volume":"11","author":"Kalafateli","year":"2012","journal-title":"Ann Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0690","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1055\/s-2008-1040417","article-title":"Small-duct primary sclerosing cholangitis","volume":"11","author":"Ludwig","year":"1991","journal-title":"Semin Liver Dis."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0695","doi-asserted-by":"crossref","first-page":"744","DOI":"10.3109\/00365529409092504","article-title":"Hepatobiliary disease in ulcerative colitis. An analysis of 18 patients with hepatobiliary lesions classified as small-duct primary sclerosing cholangitis","volume":"29","author":"Boberg","year":"1994","journal-title":"Scand J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0700","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S1089-3261(05)70140-9","article-title":"Alagille syndrome. The widening spectrum of arteriohepatic dysplasia","volume":"4","author":"Crosnier","year":"2000","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0705","series-title":"Clinical gastroenterology and hepatology","article-title":"Granulomas of the liver","author":"Bruguera","year":"2005"},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0710","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/liv.12007","article-title":"Liver involvement in Turner syndrome","volume":"33","author":"Roulot","year":"2013","journal-title":"Liver Int."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0715","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.medcli.2013.06.010","article-title":"Systematic approach to the diagnosis of hyperferritinemia","volume":"142","author":"Alt\u00e9s","year":"2014","journal-title":"Med Clin (Barc)."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0720","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.medcli.2014.10.019","article-title":"Hereditary hemochromatosis. Problems in diagnosis and treatment","volume":"144","author":"Alt\u00e9s","year":"2015","journal-title":"Med Clin (Barc)."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0725","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0140-6736(96)06034-5","article-title":"A new syndrome of liver iron overload with normal transferrin saturation","volume":"349","author":"Moirand","year":"1997","journal-title":"Lancet."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0730","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/00004836-199610000-00007","article-title":"Antimitochondrial antibody-negative chronic nonsuppurative destructive cholangitis. Atypical primary biliary cirrhosis or autoimmune cholangitis?","volume":"23","author":"S\u00e1nchez-Pobre","year":"1996","journal-title":"J Clin Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0735","first-page":"505","article-title":"\u00bfCirrosis biliar primaria at\u00edpica o colangitis autoinmune?","volume":"22","author":"Primo","year":"1999","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0740","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.cld.2007.11.008","article-title":"Anti-mitochondrial antibody-negative primary biliary cirrhosis","volume":"12","author":"Selmi","year":"2008","journal-title":"Clin Liver Dis."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0745","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1056\/NEJMra050408","article-title":"Autoimmune hepatitis","volume":"354","author":"Krawitt","year":"2006","journal-title":"N Engl J Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0750","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1034\/j.1600-0676.2003.00824.x","article-title":"Diagnostic and phenotypic classification of Wilson disease","volume":"23","author":"Ferenci","year":"2003","journal-title":"Liver Int."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0755","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.jhep.2008.11.008","article-title":"Role of genotyping in Wilson's disease","volume":"50","author":"Schmidt","year":"2009","journal-title":"J Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0760","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/S1542-3565(05)00181-3","article-title":"Diagnostic value of quantitative hepatic copper determination in patients with Wilson's Disease","volume":"3","author":"Ferenci","year":"2005","journal-title":"Clin Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0765","first-page":"707","article-title":"Prevalencia de enfermedad celiaca en hipertransaminasemia cr\u00f3nica inexplicada","volume":"93","author":"M\u00fagica","year":"2001","journal-title":"Rev Esp Enferm Dig."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0770","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.cgh.2013.10.033","article-title":"Factors that contribute to hypertransaminasemia in patients with celiac disease or functional gastrointestinal syndromes","volume":"12","author":"Zanini","year":"2014","journal-title":"Clin Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0775","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1365-2036.2011.04685.x","article-title":"Meta-analysis: Coeliac disease and hypertransaminasaemia","volume":"34","author":"Sainsbury","year":"2011","journal-title":"Aliment Pharmacol Ther."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0780","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1365-2036.2009.04186.x","article-title":"Autoimmune liver diseases in a paediatric population with coeliac disease \u2014 a 10-year single-centre experience","volume":"31","author":"Di Biase","year":"2010","journal-title":"Aliment Pharmacol Ther."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0785","first-page":"95","article-title":"Should we consider Addison's disease in the differential diagnosis of persistent hypertransaminasemia? A case report","volume":"74","author":"Anagnostis","year":"2011","journal-title":"Acta Gastroenterol Belg."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0790","doi-asserted-by":"crossref","first-page":"3010","DOI":"10.1111\/j.1572-0241.1999.01451.x","article-title":"Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients","volume":"94","author":"Daniel","year":"1999","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0795","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0168-8278(01)00094-0","article-title":"Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology","volume":"35","author":"Skelly","year":"2001","journal-title":"J Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0800","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1056\/NEJM199703203361204","article-title":"Idiopathic biliary ductopenia in adults without symptoms of liver disease","volume":"336","author":"Moreno","year":"1997","journal-title":"N Engl J Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0805","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.jhep.2003.12.019","article-title":"Isolated idiopathic bile ductular hyperplasia in patients with persistently abnormal liver function tests","volume":"40","author":"Sonzogni","year":"2004","journal-title":"J Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0810","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1097\/MEG.0b013e3283360021","article-title":"Nodular regenerative hyperplasia of the liver: Survival and associated features in a UK case series","volume":"22","author":"Morris","year":"2010","journal-title":"Eur J Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0815","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/hep.510260217","article-title":"Focal glucogenosis of the liver in disorders of ureagenesis: Its occurrence and diagnostic significance","volume":"26","author":"Badizadegan","year":"1997","journal-title":"Hepatology."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0820","doi-asserted-by":"crossref","first-page":"27","DOI":"10.5858\/2006-130-27-DHDMOT","article-title":"Diabetic hepatosclerosis: Diabetic microangiopathy of the liver","volume":"130","author":"Harrison","year":"2006","journal-title":"Arch Pathol Lab Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0825","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/01.md.0000091183.93122.c7","article-title":"Primary (AL) hepatic amyloidosis: Clinical features and natural history in 98 patients","volume":"82","author":"Park","year":"2003","journal-title":"Medicine (Baltimore)."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0830","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1093\/jac\/dkr159","article-title":"Hepatic safety of antibiotics used in primary care","volume":"66","author":"Andrade","year":"2011","journal-title":"J Antimicrob Chemother."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0835","doi-asserted-by":"crossref","first-page":"3826","DOI":"10.1016\/j.fct.2012.07.006","article-title":"Toxic hepatitis in a group of 20 male body-builders taking dietary supplements","volume":"50","author":"Timcheh-Hariri","year":"2012","journal-title":"Food Chem Toxicol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0840","doi-asserted-by":"crossref","first-page":"680","DOI":"10.7326\/0003-4819-108-5-680","article-title":"Liver disease associated with occupational exposure to the solvent dimethylformamide","volume":"108","author":"Redisch","year":"1988","journal-title":"Ann Intern Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0845","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1001\/archinte.1989.00390080065015","article-title":"Liver disease associated with exposure to 1,1,1, -trichloroethane","volume":"149","author":"Hodgson","year":"1989","journal-title":"Arch Intern Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0850","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1478-3231.1999.tb00053.x","article-title":"Nonalcoholic steatohepatitis: A toxic liver disease in industrial workers","volume":"19","author":"Cotrim","year":"1999","journal-title":"Liver."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0855","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/(SICI)1097-0274(199911)36:5<541::AID-AJIM6>3.0.CO;2-4","article-title":"Liver damage among shoe repairers","volume":"36","author":"Tomei","year":"1999","journal-title":"Am J Ind Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0860","first-page":"334","article-title":"Liver damage in workers exposed to hydrocarbons","volume":"29","author":"P\u00e9rez","year":"2006","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0865","doi-asserted-by":"crossref","first-page":"473","DOI":"10.7326\/0003-4819-111-6-473","article-title":"Is liver biopsy useful in the evaluation of patients with chronically elevated liver enzymes?","volume":"111","author":"Van Ness","year":"1989","journal-title":"Ann Intern Med."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0870","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1055\/s-2003-38644","article-title":"Clinical usefulness and diagnostic value of percutaneous liver biopsy in patients with chronically elevated liver enzymes of non-viral origin","volume":"41","author":"Schwake","year":"2003","journal-title":"Z Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0875","doi-asserted-by":"crossref","first-page":"3206","DOI":"10.1111\/j.1572-0241.2000.03293.x","article-title":"An assessment of the role of liver biopsies in asymptomatic patients with chronic liver test abnormalities","volume":"95","author":"Sorbi","year":"2000","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2016.03.001_bib0880","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/hep.22742","article-title":"Liver biopsy","volume":"49","author":"Rockey","year":"2009","journal-title":"Hepatology."}],"container-title":["Gastroenterolog\u00eda y Hepatolog\u00eda"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0210570516300127?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0210570516300127?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,16]],"date-time":"2024-06-16T04:40:09Z","timestamp":1718512809000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0210570516300127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":88,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S0210570516300127"],"URL":"https:\/\/doi.org\/10.1016\/j.gastrohep.2016.03.001","relation":{},"ISSN":["0210-5705"],"issn-type":[{"value":"0210-5705","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gu\u00eda pr\u00e1ctica para el examen del paciente adulto con hipertransaminasemia asintom\u00e1tica","name":"articletitle","label":"Article Title"},{"value":"Gastroenterolog\u00eda y Hepatolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gastrohep.2016.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Espa\u00f1a, S.L.U., AEEH y AEG. All rights reserved.","name":"copyright","label":"Copyright"}]}}