{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T04:55:14Z","timestamp":1784782514654,"version":"3.55.0"},"reference-count":116,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T00:00:00Z","timestamp":1507766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastroenterolog\u00eda y Hepatolog\u00eda"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.gastrohep.2017.08.012","type":"journal-article","created":{"date-parts":[[2017,10,27]],"date-time":"2017-10-27T04:47:25Z","timestamp":1509079645000},"page":"63-76","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Preguntas y errores en el diagn\u00f3stico y manejo de la anemia en pacientes con hemorragia digestiva"],"prefix":"10.1016","volume":"41","author":[{"given":"Ferm\u00edn","family":"Mearin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngel","family":"Lanas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Bujanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Canelles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Cotter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Herv\u00e1s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Mart\u00edn de Argila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Montoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier P.","family":"Gisbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gastrohep.2017.08.012_bib0585","first-page":"A4583","article-title":"Lack of follow-up of anaemia after discharge from an upper gastrointestinal bleeding centre","volume":"60","author":"Bager","year":"2013","journal-title":"Dan Med J."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0590","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1463-1318.2005.00789.x","article-title":"The prevalence of iron deficiency among patients presenting with colorectal cancer","volume":"7","author":"Beale","year":"2005","journal-title":"Colorectal Dis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0595","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1007\/s11605-013-2184-7","article-title":"Iron-deficiency anemia is a common presenting issue with giant paraesophageal hernia and resolves following repair","volume":"17","author":"Carrott","year":"2013","journal-title":"J Gastrointest Surg."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0600","first-page":"284","article-title":"Intestinal parasitic infections and micronutrient deficiency: A review","volume":"59","author":"Hesham","year":"2004","journal-title":"Med J Malaysia."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0605","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2169\/internalmedicine1962.24.39","article-title":"Studies on complications of diverticular disease of the colon","volume":"24","author":"Kubo","year":"1985","journal-title":"Jpn J Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0610","doi-asserted-by":"crossref","first-page":"3975","DOI":"10.3390\/nu5103975","article-title":"Vitamin and mineral deficiencies are highly prevalent in newly diagnosed celiac disease patients","volume":"5","author":"Wierdsma","year":"2013","journal-title":"Nutrients."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0615","doi-asserted-by":"crossref","first-page":"467","DOI":"10.4291\/wjgp.v5.i4.467","article-title":"Diagnosis of gastrointestinal bleeding: A practical guide for clinicians","volume":"5","author":"Kim","year":"2014","journal-title":"World J Gastrointest Pathophysiol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0620","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1038\/ajg.2012.168","article-title":"Trends for incidence of hospitalization and death due to GI complications in the United States from 2001 to 2009","volume":"107","author":"Laine","year":"2012","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0625","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1524-4733.2007.00208.x","article-title":"Estimates of costs of hospital stay for variceal and nonvariceal upper gastrointestinal bleeding in the United States","volume":"11","author":"Adam","year":"2008","journal-title":"Value Health."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0630","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/MCG.0b013e318297fb40","article-title":"Causes of bleeding and outcomes in patients hospitalized with upper gastrointestinal bleeding","volume":"48","author":"Kim","year":"2014","journal-title":"J Clin Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0635","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1365-2036.2010.04563.x","article-title":"The changing face of hospitalisation due to gastrointestinal bleeding and perforation","volume":"33","author":"Lanas","year":"2011","journal-title":"Aliment Pharmacol Ther."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0640","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1136\/gut.2010.228874","article-title":"Guidelines for the management of iron deficiency anaemia","volume":"60","author":"Goddard","year":"2011","journal-title":"Gut."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0645","first-page":"129","article-title":"Occult and obscure bleeding, iron deficiency anemia and other gastrointestinal stories (Review)","volume":"15","author":"Marignani","year":"2005","journal-title":"Int J Mol Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0650","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1007\/s10620-009-1108-6","article-title":"Evaluation and treatment of iron deficiency anemia: A gastroenterological perspective","volume":"55","author":"Zhu","year":"2010","journal-title":"Dig Dis Sci."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0655","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.jemermed.2015.08.010","article-title":"Factors associated with hospitalization among emergency department patients referred for quick investigation of iron-deficiency anemia","volume":"50","author":"Bosch","year":"2016","journal-title":"J Emerg Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0660","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.3748\/wjg.v16.i22.2720","article-title":"Treatment of iron deficiency anemia associated with gastrointestinal tract diseases","volume":"16","author":"Bayraktar","year":"2010","journal-title":"World J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0665","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/S0140-6736(86)91269-9","article-title":"Relation of haemoglobin levels in first and second trimesters to outcome of pregnancy","volume":"1","author":"Murphy","year":"1986","journal-title":"Lancet."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0670","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1053\/j.ajkd.2015.11.020","article-title":"Red cell distribution width and mortality in hemodialysis patients","volume":"68","author":"Vashistha","year":"2016","journal-title":"Am J Kidney Dis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0675","first-page":"14","article-title":"The consequences of iron deficiency and anaemia in pregnancy on maternal health, the foetus and the infant","author":"Viteri","year":"1994","journal-title":"SCN News."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0680","doi-asserted-by":"crossref","first-page":"7908","DOI":"10.3748\/wjg.v22.i35.7908","article-title":"Anemia and iron deficiency in gastrointestinal and liver conditions","volume":"22","author":"Stein","year":"2016","journal-title":"World J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0685","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1002\/ibd.20285","article-title":"Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases","volume":"13","author":"Gasche","year":"2007","journal-title":"Inflamm Bowel Dis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0690","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/nrgastro.2010.151","article-title":"Diagnosis and management of iron deficiency anemia in patients with IBD","volume":"7","author":"Stein","year":"2010","journal-title":"Nat Rev Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0695","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1111\/j.1572-0241.2008.01846.x","article-title":"Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease","volume":"103","author":"Gisbert","year":"2008","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0700","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3389\/fphar.2014.00083","article-title":"Iron deficiency in the elderly population, revisited in the hepcidin era","volume":"5","author":"Busti","year":"2014","journal-title":"Front Pharmacol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0705","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.soard.2014.09.028","article-title":"Inflammation and iron status in bariatric surgery candidates","volume":"11","author":"Careaga","year":"2015","journal-title":"Surg Obes Relat Dis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0710","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1007\/s11695-014-1325-8","article-title":"Medication cost is significantly reduced after Roux-en-Y gastric bypass in obese patients","volume":"24","author":"Gesquiere","year":"2014","journal-title":"Obes Surg."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0715","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1007\/s11695-013-0939-6","article-title":"Comparative review of the safety and efficacy of ferric carboxymaltose versus standard medical care for the treatment of iron deficiency anemia in bariatric and gastric surgery patients","volume":"23","author":"Malone","year":"2013","journal-title":"Obes Surg."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0720","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.soard.2013.01.019","article-title":"Management of iron deficiency and anemia after Roux-en-Y gastric bypass surgery: An observational study","volume":"9","author":"Malone","year":"2013","journal-title":"Surg Obes Relat Dis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0725","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/nrgastro.2013.243","article-title":"Clinical effects of Helicobacter pylori outside the stomach","volume":"11","author":"Franceschi","year":"2014","journal-title":"Nat Rev Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0730","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/S0140-6736(14)60696-6","article-title":"Global, regional, and national levels and causes of maternal mortality during 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013","volume":"384","author":"Kassebaum","year":"2014","journal-title":"Lancet."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0735","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.gastrohep.2013.05.006","article-title":"[Prevalence and characteristics of anemia and iron deficiency in patients hospitalized for gastrointestinal diseases in Spain]","volume":"36","author":"Mearin","year":"2013","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0740","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/00054725-200005000-00013","article-title":"Anemia in IBD: The overlooked villain","volume":"6","author":"Gasche","year":"2000","journal-title":"Inflamm Bowel Dis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0745","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1136\/gut.2003.035758","article-title":"Iron, anaemia, and inflammatory bowel diseases","volume":"53","author":"Gasche","year":"2004","journal-title":"Gut."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0750","doi-asserted-by":"crossref","first-page":"909","DOI":"10.3109\/00365521.2014.910544","article-title":"Patient-reported outcomes after acute nonvariceal upper gastrointestinal hemorrhage","volume":"49","author":"Bager","year":"2014","journal-title":"Scand J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0755","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1046\/j.1365-2648.2003.02660.x","article-title":"Symptom status and health-related quality of life: Clinical relevance","volume":"42","author":"Sousa","year":"2003","journal-title":"J Adv Nurs."},{"issue":"Suppl. 7A","key":"10.1016\/j.gastrohep.2017.08.012_bib0760","article-title":"Anemia and its clinical consequences in patients with chronic diseases","volume":"116","author":"Goodnough","year":"2004","journal-title":"Am J Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0765","doi-asserted-by":"crossref","first-page":"676S","DOI":"10.1093\/jn\/131.2.676S","article-title":"Iron deficiency and reduced work capacity: A critical review of the research to determine a causal relationship","volume":"131","author":"Haas","year":"2001","journal-title":"J Nutr."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0770","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/01.MIB.0000196646.64615.db","article-title":"Effects of changes in hemoglobin level on quality of life and cognitive function in inflammatory bowel disease patients","volume":"12","author":"Wells","year":"2006","journal-title":"Inflamm Bowel Dis."},{"issue":"Suppl. 7A","key":"10.1016\/j.gastrohep.2017.08.012_bib0775","doi-asserted-by":"crossref","first-page":"44S","DOI":"10.1016\/j.amjmed.2003.12.011","article-title":"Prevalence and outcomes of anemia in inflammatory bowel disease: A systematic review of the literature","volume":"116","author":"Wilson","year":"2004","journal-title":"Am J Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0780","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1053\/j.gastro.2011.06.005","article-title":"FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease","volume":"141","author":"Evstatiev","year":"2011","journal-title":"Gastroenterology."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0785","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1093\/ajcn\/85.3.778","article-title":"Iron treatment normalizes cognitive functioning in young women","volume":"85","author":"Murray-Kolb","year":"2007","journal-title":"Am J Clin Nutr."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0790","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/S0140-6736(96)02341-0","article-title":"Randomised study of cognitive effects of iron supplementation in non-anaemic iron-deficient adolescent girls","volume":"348","author":"Bruner","year":"1996","journal-title":"Lancet."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0795","doi-asserted-by":"crossref","first-page":"e94217","DOI":"10.1371\/journal.pone.0094217","article-title":"Evaluation of a single dose of ferric carboxymaltose in fatigued, iron-deficient women \u2014 PREFER a randomized, placebo-controlled study","volume":"9","author":"Favrat","year":"2014","journal-title":"PloS One."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0800","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.gastrohep.2015.02.012","article-title":"Incidence and predictive factors of iron deficiency anemia after acute non-variceal upper gastrointestinal bleeding without portal hypertension [Spanish]","volume":"38","author":"Planella de Rubinat","year":"2015","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0805","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1097\/MEG.0b013e328365ca7f","article-title":"Anaemia management in patients with inflammatory bowel disease: Routine practice across nine European countries","volume":"25","author":"Stein","year":"2013","journal-title":"Eur J Gastroenterol Hepatol."},{"issue":"Suppl. 1","key":"10.1016\/j.gastrohep.2017.08.012_bib0810","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.2215\/CJN.01490506","article-title":"Assessing iron status: Beyond serum ferritin and transferrin saturation","volume":"1","author":"Wish","year":"2006","journal-title":"Clin J Am Soc Nephrol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0815","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.3945\/ajcn.114.103366","article-title":"Guidelines on the diagnosis and treatment of iron deficiency across indications: A systematic review","volume":"102","author":"Peyrin-Biroulet","year":"2015","journal-title":"Am J Clin Nutr."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0820","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/ecco-jcc\/jju009","article-title":"European consensus on the diagnosis and management of iron deficiency and anaemia in inflammatory bowel diseases","volume":"9","author":"Dignass","year":"2015","journal-title":"J Crohns Colitis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0825","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.crohns.2012.09.005","article-title":"Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: Special situations","volume":"7","author":"Van Assche","year":"2013","journal-title":"J Crohns Colitis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0830","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1056\/NEJMra041809","article-title":"Anemia of chronic disease","volume":"252","author":"Weiss","year":"2005","journal-title":"N Engl J Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0835","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1185\/030079906X89720","article-title":"Identification, diagnosis, and management of anemia in adult ambulatory patients treated by primary care physicians: Evidence-based and consensus recommendations","volume":"22","author":"Dubois","year":"2006","journal-title":"Curr Med Res Opin."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0840","doi-asserted-by":"crossref","first-page":"2436","DOI":"10.1056\/NEJMoa0908355","article-title":"Ferric carboxymaltose in patients with heart failure and iron deficiency","volume":"361","author":"Anker","year":"2009","journal-title":"N Engl J Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0845","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/eurheartj\/ehu385","article-title":"Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency","volume":"36","author":"Ponikowski","year":"2015","journal-title":"Eur Heart J."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0850","first-page":"40","article-title":"Prevalencia de d\u00e9ficit de hierro sin anemia en la enfermedad inflamatoria intestinal y su impacto en la calidad de vida [Spanish]","volume":"39","author":"Gonz\u00e1lez Alay\u00f3n","year":"2016","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0855","doi-asserted-by":"crossref","first-page":"73","DOI":"10.33590\/emjgastroenterol\/10314028","article-title":"the management of acute upper gastrointestinal bleeding: A comparison of current clinical guidelines and best practice","volume":"3","author":"Taylor","year":"2014","journal-title":"EMJ Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0860","first-page":"118","article-title":"Tratamiento de anemia secundaria a hemorragia digestiva con hierro carboximaltosa intravenoso en un hospital de d\u00eda m\u00e9dico [Spanish]","volume":"39","author":"Jeric\u00f3","year":"2016","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0865","first-page":"106","article-title":"Ferroterapia intravenosa en pacientes con angiodisplasia gastrointestinal [Spanish]","volume":"39","author":"L\u00f3pez-Su\u00e1rez","year":"2016","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0870","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1001\/archinte.160.14.2093","article-title":"Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding\/perforation: An overview of epidemiologic studies published in the 1990s","volume":"160","author":"Hernandez-Diaz","year":"2000","journal-title":"Arch Intern Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0875","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/j.1365-2036.2006.03043.x","article-title":"Systematic review: The lower gastrointestinal adverse effects of non-steroidal anti-inflammatory drugs","volume":"24","author":"Laine","year":"2006","journal-title":"Aliment Pharmacol Ther."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0880","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3390\/pharmaceutics3010012","article-title":"The pharmacokinetics and pharmacodynamics of iron preparations","volume":"3","author":"Geisser","year":"2011","journal-title":"Pharmaceutics."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0885","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1517\/14656566.2012.669373","article-title":"Ferric carboxymaltose for the treatment of iron-deficiency anemia [corrected]","volume":"13","author":"Mu\u00f1oz","year":"2012","journal-title":"Expert Opin Pharmacother."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0890","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.amjcard.2007.07.067","article-title":"Relation of low hemoglobin and anemia to morbidity and mortality in patients hospitalized with heart failure (insight from the OPTIMIZE-HF registry)","volume":"101","author":"Young","year":"2008","journal-title":"Am J Cardiol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0895","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1002\/cncr.10763","article-title":"Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy","volume":"95","author":"Crawford","year":"2002","journal-title":"Cancer."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0900","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1038\/ajg.2009.114","article-title":"Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment","volume":"104","author":"Kulnigg","year":"2009","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0905","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1093\/ndt\/gfi253","article-title":"Update on adverse drug events associated with parenteral iron","volume":"21","author":"Chertow","year":"2006","journal-title":"Nephrol Dial Transplant."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0910","unstructured":"European Medicines Agency. Assessment report for: Iron containing intravenous (IV) medicinal products [consultado 20 May 2017]. Disponible en:. http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Referrals_document\/IV_iron_31\/WC500150771.pdf"},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0915","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/annonc\/mds338","article-title":"Clinical experience with ferric carboxymaltose in the treatment of cancer and chemotherapy-associated anaemia","volume":"24","author":"Steinmetz","year":"2013","journal-title":"Ann Oncol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0920","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00520-015-2728-3","article-title":"Clinical use of ferric carboxymaltose in patients with solid tumours or haematological malignancies in France","volume":"24","author":"Toledano","year":"2016","journal-title":"Support Care Cancer."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0925","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s10620-008-0708-x","article-title":"Risk factors for gastrointestinal ulcer disease in the US population","volume":"55","author":"Garrow","year":"2010","journal-title":"Dig Dis Sci."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0930","doi-asserted-by":"crossref","first-page":"e1482","DOI":"10.1097\/MD.0000000000001482","article-title":"Different risk of common gastrointestinal disease between groups undergoing hemodialysis or peritoneal dialysis or with non-end stage renal disease: A nationwide population-based cohort study","volume":"94","author":"Lee","year":"2015","journal-title":"Medicine (Baltimore)."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0935","doi-asserted-by":"crossref","first-page":"e010439","DOI":"10.1136\/bmjopen-2015-010439","article-title":"Upper gastrointestinal bleeding as a risk factor for dialysis and all-cause mortality: A cohort study of chronic kidney disease patients in Taiwan","volume":"6","author":"Liang","year":"2016","journal-title":"BMJ Open."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0940","first-page":"279","article-title":"KDIGO clinical practice guideline for anemia in chronic kidney disease","volume":"2","year":"2012","journal-title":"Kidney Inter Suppl."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0945","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1136\/gut.2010.214312","article-title":"Iron sensing and signalling","volume":"61","author":"Evstatiev","year":"2012","journal-title":"Gut."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0950","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1111\/j.1572-0241.2007.01744.x","article-title":"A novel intravenous iron formulation for treatment of anemia in inflammatory bowel disease: The ferric carboxymaltose (FERINJECT) randomized controlled trial","volume":"103","author":"Kulnigg","year":"2008","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0955","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1038\/ajg.2013.335","article-title":"A randomized, open-label, non-inferiority study of intravenous iron isomaltoside 1,000 (Monofer) compared with oral iron for treatment of anemia in IBD (PROCEED)","volume":"108","author":"Reinisch","year":"2013","journal-title":"Am J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0960","first-page":"301","article-title":"[Intravenous iron-dextran: Therapeutic and experimental possibilities]","volume":"100","author":"Ganzoni","year":"1970","journal-title":"Schweiz Med Wochenschr."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0965","unstructured":"Vifor Pharma. Summary of Product Characteristics, Ferinject\u00ae [consultado 20 May 2017]. Disponible en: http:\/\/www.mhra.gov.uk\/home\/groups\/spcpil\/documents\/spcpil\/con1470978881197.pdf"},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0970","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.cgh.2012.10.013","article-title":"Ferric carboxymaltose prevents recurrence of anemia in patients with inflammatory bowel disease","volume":"11","author":"Evstatiev","year":"2013","journal-title":"Clin Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0975","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/apt.12556","article-title":"Randomised clinical trial: Oral vs. intravenous iron after upper gastrointestinal haemorrhage \u2014 a placebo-controlled study","volume":"39","author":"Bager","year":"2014","journal-title":"Aliment Pharmacol Ther."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0980","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1080\/00365520902839667","article-title":"Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: A randomized, controlled, evaluator-blind, multicentre study","volume":"44","author":"Lindgren","year":"2009","journal-title":"Scand J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0985","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.freeradbiomed.2013.09.001","article-title":"The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress","volume":"65","author":"Koskenkorva-Frank","year":"2013","journal-title":"Free Radic Biol Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0990","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1046\/j.1365-2141.1999.01179.x","article-title":"Pharmacokinetics and red cell utilization of iron(III) hydroxide-sucrose complex in anaemic patients: A study using positron emission tomography","volume":"104","author":"Beshara","year":"1999","journal-title":"Br J Haematol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib0995","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1046\/j.1365-2141.2003.03590.x","article-title":"Pharmacokinetics and red cell utilization of 52Fe\/59Fe-labelled iron polymaltose in anaemic patients using positron emission tomography","volume":"120","author":"Beshara","year":"2003","journal-title":"Br J Haematol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1000","first-page":"105","article-title":"Tratamiento con carboximaltosa de hierro en pacientes derivados por la unidad de digestivo [Spanish]","volume":"39","author":"L\u00f3pez-Su\u00e1rez","year":"2016","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1005","first-page":"133","article-title":"Tratamiento de la anemia ferrop\u00e9nica posthemorragia digestiva aguda: ferroterapia oral frente a intravenosa [Spanish]","volume":"39","author":"Ferrer-Barcel\u00f3","year":"2016","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1010","first-page":"159","article-title":"Efficacy and safety of ferric carboxymaltose treatment in patients hospitalized for acute gastrointestinal bleeding not associated with portal hypertension [Spanish]","volume":"40","author":"Torres Vicente","year":"2016","journal-title":"Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1015","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00384-015-2461-x","article-title":"Ferric carboxymaltose reduces transfusions and hospital stay in patients with colon cancer and anemia","volume":"31","author":"Calleja","year":"2016","journal-title":"Int J Colorectal Dis."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1020","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1002\/bjs.6688","article-title":"Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery","volume":"96","author":"Edwards","year":"2009","journal-title":"Br J Surg."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1025","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bja\/aev165","article-title":"\u2018Fit to fly\u2019: Overcoming barriers to preoperative haemoglobin optimization in surgical patients","volume":"115","author":"Mu\u00f1oz","year":"2015","journal-title":"Br J Anaesth."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1030","unstructured":"Canadian Agency for Drugs and Technologies in Health. Ferumoxytol versus other intravenous iron therapies for anemia: A review of the clinical and cost-effectiveness and guidelines \u2013 An Update. PM: 25520994 [consultado 1 Feb 2016]. Disponible en: http:\/\/www.ncbi.nlm.nih.gov\/pubmedhealth\/PMH0071241\/"},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1035","unstructured":"European Medicines Agency. Rienso. Withdrawal of the marketing authorisation in the European Union [consultado 27 Abr 2017]. Disponible en: www.ema.europa.eu\/docs\/en_GB\/document_library\/Public_statement\/2015\/07\/WC500189474.pdf"},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1040","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1016\/S0140-6736(07)60689-8","article-title":"Clinical update: Intravenous iron for anaemia","volume":"369","author":"Auerbach","year":"2007","journal-title":"Lancet."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1045","first-page":"600","article-title":"Adverse events associated with intravenous iron preparations: A comparison of reported rates","volume":"10","author":"Bailie","year":"2012","journal-title":"Clin Adv Hematol Oncol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1050","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.mayocp.2014.10.007","article-title":"The safety of intravenous iron preparations: Systematic review and meta-analysis","volume":"90","author":"Avni","year":"2015","journal-title":"Mayo Clin Proc."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1055","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0140-6736(14)61999-1","article-title":"Restrictive versus liberal blood transfusion for acute upper gastrointestinal bleeding (TRIGGER): A pragmatic, open-label, cluster randomised feasibility trial","volume":"386","author":"Jairath","year":"2015","journal-title":"Lancet."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1060","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/nrgastro.2015.116","article-title":"Gastrointestinal bleeding: Blood transfusion for acute upper gastrointestinal bleeding","volume":"12","author":"Villanueva","year":"2015","journal-title":"Nat Rev Gastroenterol Hepatol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1065","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1211801","article-title":"Transfusion strategies for acute upper gastrointestinal bleeding","volume":"368","author":"Villanueva","year":"2013","journal-title":"N Engl J Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1070","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1111\/trf.13794","article-title":"Ferric carboxymaltose reduces the number of red blood cell units transfused and allows transfusion independence to be obtained in patients with iron deficiency anemia secondary to gastrointestinal chronic blood loss","volume":"56","author":"Salvadori","year":"2016","journal-title":"Transfusion."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1075","unstructured":"American Association of Blood Banks. Five things physicians and patients should question [consultado 3 Ago 2017]. Disponible en: http:\/\/www.choosingwisely.org\/wp-content\/uploads\/2015\/02\/AABB-Choosing-Wisely-List.pdf"},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1080","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1056\/NEJMcp1514257","article-title":"CLINICAL PRACTICE. Upper gastrointestinal bleeding due to a peptic ulcer","volume":"374","author":"Laine","year":"2016","journal-title":"N Engl J Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1085","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1542\/peds.108.3.613","article-title":"Randomized, controlled trial of single versus 3-times-daily ferrous sulfate drops for treatment of anemia","volume":"108","author":"Zlotkin","year":"2001","journal-title":"Pediatrics."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1090","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1053\/j.gastro.2005.12.051","article-title":"Treatment of iron deficiency","volume":"130","author":"Rockey","year":"2006","journal-title":"Gastroenterology."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1095","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.amjmed.2005.01.065","article-title":"Are we giving too much iron? Low-dose iron therapy is effective in octogenarians","volume":"118","author":"Rimon","year":"2005","journal-title":"Am J Med."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1100","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/ajcn\/78.1.145","article-title":"Efficacy and tolerability of low-dose iron supplements during pregnancy: A randomized controlled trial","volume":"78","author":"Makrides","year":"2003","journal-title":"Am J Clin Nutr."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1105","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.amjmed.2008.07.012","article-title":"Individualized treatment for iron-deficiency anemia in adults","volume":"121","author":"Alleyne","year":"2008","journal-title":"Am J Med."},{"issue":"Suppl. 4","key":"10.1016\/j.gastrohep.2017.08.012_bib1110","doi-asserted-by":"crossref","first-page":"813s","DOI":"10.1093\/jn\/132.4.813S","article-title":"Iron supplements: Scientific issues concerning efficacy and implications for research and programs","volume":"132","author":"Allen","year":"2002","journal-title":"J Nutr."},{"issue":"Suppl. 9","key":"10.1016\/j.gastrohep.2017.08.012_bib1115","first-page":"S1","article-title":"Medication compliance: A healthcare problem","volume":"27","author":"Berg","year":"1993","journal-title":"Ann Pharmacother."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1120","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1200\/JCO.2003.07.071","article-title":"Nonadherence to adjuvant tamoxifen therapy in women with primary breast cancer","volume":"21","author":"Partridge","year":"2003","journal-title":"J Clin Oncol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1125","doi-asserted-by":"crossref","first-page":"739","DOI":"10.2165\/00003495-200969060-00007","article-title":"Ferric carboxymaltose: A review of its use in iron-deficiency anaemia","volume":"69","author":"Lyseng-Williamson","year":"2009","journal-title":"Drugs."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1130","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1080\/00365520510023198","article-title":"Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease","volume":"40","author":"Erichsen","year":"2005","journal-title":"Scand J Gastroenterol."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1135","first-page":"91","article-title":"Iron-deficiency anaemia in the Emergency Room: A new opportunity for the use of intravenous iron","volume":"14","author":"Morhaim","year":"2016","journal-title":"Blood Transfus."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1140","first-page":"126","article-title":"A fast-track anaemia clinic in the Emergency Department: Feasibility and efficacy of intravenous iron administration for treating sub-acute iron deficiency anaemia","volume":"14","author":"Quintana-D\u00edaz","year":"2016","journal-title":"Blood Transfus."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1145","first-page":"438","article-title":"A fast-track anaemia clinic in the Emergency Department: Cost-analysis of intravenous iron administration for treating iron-deficiency anaemia","volume":"15","author":"Quintana-D\u00edaz","year":"2017","journal-title":"Blood Transfus."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1150","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1093\/jn\/132.8.2298","article-title":"Low income postpartum women are at risk of iron deficiency","volume":"132","author":"Bodnar","year":"2002","journal-title":"J Nutr."},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1155","unstructured":"World Health Organization. Worldwide prevalence of anaemia 1993-2005 [consultado 20 May 2017]. Disponible en: http:\/\/www.who.int\/nutrition\/publications\/micronutrients\/anaemia_iron_deficiency\/9789241596657\/en"},{"key":"10.1016\/j.gastrohep.2017.08.012_bib1160","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3233\/THC-151074","article-title":"Cost-minimization analysis favours intravenous ferric carboxymaltose over ferric sucrose or oral iron as preoperative treatment in patients with colon cancer and iron deficiency anaemia","volume":"24","author":"Calvet","year":"2016","journal-title":"Technol Health Care."}],"container-title":["Gastroenterolog\u00eda y Hepatolog\u00eda"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0210570517302200?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0210570517302200?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T17:27:08Z","timestamp":1693157228000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0210570517302200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":116,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S0210570517302200"],"URL":"https:\/\/doi.org\/10.1016\/j.gastrohep.2017.08.012","relation":{},"ISSN":["0210-5705"],"issn-type":[{"value":"0210-5705","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preguntas y errores en el diagn\u00f3stico y manejo de la anemia en pacientes con hemorragia digestiva","name":"articletitle","label":"Article Title"},{"value":"Gastroenterolog\u00eda y Hepatolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gastrohep.2017.08.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}